{"id":"https://openalex.org/W1965547925","doi":"https://doi.org/10.1210/jcem-18-2-208","title":"STUDY OF THE NORYMBERSKI METHODS FOR DETERMINATION OF 17-KETOGENIC STEROIDS (17-HYDROXYCORTICOSTEROIDS) IN URINE","display_name":"STUDY OF THE NORYMBERSKI METHODS FOR DETERMINATION OF 17-KETOGENIC STEROIDS (17-HYDROXYCORTICOSTEROIDS) IN URINE","publication_year":1958,"publication_date":"1958-02-01","ids":{"openalex":"https://openalex.org/W1965547925","doi":"https://doi.org/10.1210/jcem-18-2-208","mag":"1965547925","pmid":"https://pubmed.ncbi.nlm.nih.gov/13502449"},"language":"en","primary_location":{"id":"doi:10.1210/jcem-18-2-208","doi":"https://doi.org/10.1210/jcem-18-2-208","is_oa":false,"landing_page_url":"https://doi.org/10.1210/jcem-18-2-208","pdf_url":null,"source":{"id":"https://openalex.org/S205775358","display_name":"The Journal of Clinical Endocrinology & Metabolism","issn_l":"0021-972X","issn":["0021-972X","1945-7197"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Clinical Endocrinology & Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009032915","display_name":"Charles Sobel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"CHARLES SOBEL","raw_affiliation_strings":["Bio-Science Research Foundation Los Angeles, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-Science Research Foundation Los Angeles, California","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109918645","display_name":"Orville J. Golub","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"ORVILLE J. GOLUB","raw_affiliation_strings":["Bio-Science Research Foundation Los Angeles, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-Science Research Foundation Los Angeles, California","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110307644","display_name":"Richard J. Henry","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"RICHARD J. HENRY","raw_affiliation_strings":["Bio-Science Research Foundation Los Angeles, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-Science Research Foundation Los Angeles, California","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038464884","display_name":"Stanley Jacobs","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. L. JACOBS","raw_affiliation_strings":["Bio-Science Research Foundation Los Angeles, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-Science Research Foundation Los Angeles, California","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103634112","display_name":"GOPAL K. BASU","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"GOPAL K. BASU","raw_affiliation_strings":["Bio-Science Research Foundation Los Angeles, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-Science Research Foundation Los Angeles, California","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":null,"fwci":12.4721,"has_fulltext":false,"cited_by_count":95,"citation_normalized_percentile":{"value":0.98890905,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":"2","first_page":"208","last_page":"221"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.027499999850988388,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/17-ketogenic-steroids","display_name":"17-ketogenic steroids","score":0.9049999713897705},{"id":"https://openalex.org/keywords/17-hydroxycorticosteroids","display_name":"17-hydroxycorticosteroids","score":0.9909999966621399},{"id":"https://openalex.org/keywords/zimmermann-reaction","display_name":"Zimmermann reaction","score":0.9679999947547913},{"id":"https://openalex.org/keywords/borohydride-reduction","display_name":"borohydride reduction","score":0.9570000171661377},{"id":"https://openalex.org/keywords/method-precision","display_name":"method precision","score":0.4970000088214874}],"concepts":[{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.7180521488189697},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7155967950820923},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.6248892545700073},{"id":"https://openalex.org/C2778931688","wikidata":"https://www.wikidata.org/wiki/Q56703505","display_name":"Borohydride","level":3,"score":0.5733364224433899},{"id":"https://openalex.org/C40875361","wikidata":"https://www.wikidata.org/wiki/Q2356542","display_name":"Reagent","level":2,"score":0.4909811317920685},{"id":"https://openalex.org/C2778587478","wikidata":"https://www.wikidata.org/wiki/Q1070684","display_name":"Ketogenic diet","level":3,"score":0.4389493465423584},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3731454312801361},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35536104440689087},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1663406491279602},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.13448035717010498},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12344759702682495},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.06312209367752075},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000305","descriptor_name":"Adrenal Cortex Hormones","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D001826","descriptor_name":"Body Fluids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015065","descriptor_name":"17-Hydroxycorticosteroids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1210/jcem-18-2-208","doi":"https://doi.org/10.1210/jcem-18-2-208","is_oa":false,"landing_page_url":"https://doi.org/10.1210/jcem-18-2-208","pdf_url":null,"source":{"id":"https://openalex.org/S205775358","display_name":"The Journal of Clinical Endocrinology & Metabolism","issn_l":"0021-972X","issn":["0021-972X","1945-7197"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Clinical Endocrinology & Metabolism","raw_type":"journal-article"},{"id":"pmid:13502449","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/13502449","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical endocrinology and metabolism","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2039371745","https://openalex.org/W2085302200","https://openalex.org/W1968821620","https://openalex.org/W2122058157","https://openalex.org/W2108489368","https://openalex.org/W1989210042","https://openalex.org/W2019992006","https://openalex.org/W2046383206","https://openalex.org/W2419064261","https://openalex.org/W2266187924"],"abstract_inverted_index":{"Modified":[0],"methods":[1,71],"for":[2,37,39,58,72],"the":[3,18,45,70,90,93],"determination":[4],"of":[5,28,32,44,61,69,82,86],"17-ketogenic":[6,75,94],"steroids":[7,76,95],"by":[8,63],"direct":[9],"and":[10,26,35,51,74,92],"indirect":[11],"procedures":[12],"are":[13,65],"presented.":[14,66],"Several":[15],"factors":[16],"in":[17],"Zimmermann":[19],"reaction":[20,48],"were":[21],"studied":[22,50],"experimentally;":[23],"namely,":[24],"time":[25],"temperature":[27,103],"color":[29],"development,":[30],"composition":[31],"reagents,":[33],"specificity":[34],"method":[36],"correcting":[38],"background":[40],"absorbance.":[41],"The":[42,67],"stoichiometry":[43],"bismuthate":[46],"oxidation":[47],"was":[49,77],"shown":[52],"to":[53,97],"effect":[54],"satisfactory":[55],"recoveries.":[56],"Conditions":[57],"quantitative":[59],"reduction":[60],"17-ketosteroids":[62,73,91],"borohydride":[64],"precision":[68],"determined.":[78],"From":[79],"a":[80,83],"study":[81],"limited":[84],"number":[85],"urine":[87],"samples,":[88],"both":[89],"appear":[96],"be":[98],"relatively":[99],"stable":[100],"at":[101],"room":[102],"without":[104],"added":[105],"preservative.":[106]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}