{"id":"https://openalex.org/W1965541888","doi":"https://doi.org/10.1016/0047-6374(94)90103-1","title":"Elastin degradation in the aorta of Watanabe hereditary hyperlipidemic rabbits","display_name":"Elastin degradation in the aorta of Watanabe hereditary hyperlipidemic rabbits","publication_year":1994,"publication_date":"1994-05-01","ids":{"openalex":"https://openalex.org/W1965541888","doi":"https://doi.org/10.1016/0047-6374(94)90103-1","mag":"1965541888","pmid":"https://pubmed.ncbi.nlm.nih.gov/7934202"},"language":"en","primary_location":{"id":"doi:10.1016/0047-6374(94)90103-1","doi":"https://doi.org/10.1016/0047-6374(94)90103-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0047-6374(94)90103-1","pdf_url":null,"source":{"id":"https://openalex.org/S6761461","display_name":"Mechanisms of Ageing and Development","issn_l":"0047-6374","issn":["0047-6374","1872-6216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mechanisms of Ageing and Development","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072519336","display_name":"Kathie M. Dalessandri","orcid":"https://orcid.org/0000-0002-7666-7317","observed_orcids":["https://orcid.org/0000-0002-7666-7317"]},"institutions":[{"id":"https://openalex.org/I204866599","display_name":"VA Palo Alto Health Care System","ror":"https://ror.org/00nr17z89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I204866599","https://openalex.org/I2799886695","https://openalex.org/I4210125474"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kathie M. Dalessandri","raw_affiliation_strings":["Department of Surgery (112), Palo Alto VA Hospital, CA 94304","Department of Surgery (112), Palo Alto VA Hospital, Palo Alto, CA 94304, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery (112), Palo Alto VA Hospital, CA 94304","institution_ids":["https://openalex.org/I204866599"]},{"raw_affiliation_string":"Department of Surgery (112), Palo Alto VA Hospital, Palo Alto, CA 94304, USA","institution_ids":["https://openalex.org/I204866599"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027006986","display_name":"Pamela H. Eisele","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pamela Eisele","raw_affiliation_strings":["Animal Resources Service, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal Resources Service, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045892751","display_name":"Toniel S. Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Toniel S. Wong","raw_affiliation_strings":["Department of Nutrition, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091729556","display_name":"Jackie Parker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jackie Parker","raw_affiliation_strings":["Animal Resources Service, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal Resources Service, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015043500","display_name":"Robert B. Rucker","orcid":"https://orcid.org/0000-0002-7804-0278","observed_orcids":["https://orcid.org/0000-0002-7804-0278"]},"institutions":[{"id":"https://openalex.org/I204866599","display_name":"VA Palo Alto Health Care System","ror":"https://ror.org/00nr17z89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I204866599","https://openalex.org/I2799886695","https://openalex.org/I4210125474"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert B. Rucker","raw_affiliation_strings":["Department of Nutrition, University of California, Davis, CA 95616, USA","Department of Surgery (112), Palo Alto VA Hospital, Palo Alto, CA 94304, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Department of Surgery (112), Palo Alto VA Hospital, Palo Alto, CA 94304, USA","institution_ids":["https://openalex.org/I204866599"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5015043500"],"corresponding_institution_ids":["https://openalex.org/I204866599","https://openalex.org/I84218800"],"apc_list":{"value":4780,"currency":"USD","value_usd":4780},"apc_paid":null,"fwci":0.278,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.50057197,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"74","issue":"1-2","first_page":"117","last_page":"120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.39010000228881836,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.39010000228881836,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12924","display_name":"Dermatological and Skeletal Disorders","score":0.3783999979496002,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11310","display_name":"Connective tissue disorders research","score":0.06650000065565109,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/elastin-degradation","display_name":"elastin degradation","score":0.9829999804496765},{"id":"https://openalex.org/keywords/elastolysis","display_name":"elastolysis","score":0.703000009059906},{"id":"https://openalex.org/keywords/familial-hyperlipidemia","display_name":"familial hyperlipidemia","score":0.8529999852180481},{"id":"https://openalex.org/keywords/thoracic-aorta","display_name":"thoracic aorta","score":0.8460000157356262},{"id":"https://openalex.org/keywords/lysyl-oxidase","display_name":"lysyl oxidase","score":0.9399999976158142},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.5630000233650208}],"concepts":[{"id":"https://openalex.org/C2779869378","wikidata":"https://www.wikidata.org/wiki/Q409747","display_name":"Elastin","level":2,"score":0.933516263961792},{"id":"https://openalex.org/C2779091943","wikidata":"https://www.wikidata.org/wiki/Q1079120","display_name":"Hyperlipidemia","level":3,"score":0.6419709920883179},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6265147924423218},{"id":"https://openalex.org/C2779980429","wikidata":"https://www.wikidata.org/wiki/Q101004","display_name":"Aorta","level":2,"score":0.5946365594863892},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5809845924377441},{"id":"https://openalex.org/C2776864027","wikidata":"https://www.wikidata.org/wiki/Q615993","display_name":"Thoracic aorta","level":3,"score":0.5668420195579529},{"id":"https://openalex.org/C193143273","wikidata":"https://www.wikidata.org/wiki/Q419389","display_name":"Lysyl oxidase","level":3,"score":0.4354560375213623},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4030718207359314},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3635520040988922},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2756648659706116},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.18943703174591064},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1614973545074463},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.1540614366531372}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004549","descriptor_name":"Elastin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008249","descriptor_name":"Protein-Lysine 6-Oxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012995","descriptor_name":"Solubility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0047-6374(94)90103-1","doi":"https://doi.org/10.1016/0047-6374(94)90103-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0047-6374(94)90103-1","pdf_url":null,"source":{"id":"https://openalex.org/S6761461","display_name":"Mechanisms of Ageing and Development","issn_l":"0047-6374","issn":["0047-6374","1872-6216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mechanisms of Ageing and Development","raw_type":"journal-article"},{"id":"pmid:7934202","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7934202","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mechanisms of ageing and development","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1915025757","https://openalex.org/W1978582021","https://openalex.org/W2005767515","https://openalex.org/W2017526797","https://openalex.org/W2067776836","https://openalex.org/W2084073097","https://openalex.org/W2094464913","https://openalex.org/W2132944850","https://openalex.org/W2151624907","https://openalex.org/W2411982894","https://openalex.org/W2415259858"],"related_works":["https://openalex.org/W2132944850","https://openalex.org/W2786753398","https://openalex.org/W2411982894","https://openalex.org/W2048562587","https://openalex.org/W2390531262","https://openalex.org/W2784077719","https://openalex.org/W7001996212","https://openalex.org/W2005993526","https://openalex.org/W2021404036","https://openalex.org/W1979878255"],"abstract_inverted_index":null,"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}