{"id":"https://openalex.org/W1965391982","doi":"https://doi.org/10.1358/dot.1998.34.7.484111","title":"Diagnosis and treatment of irritable bowel syndrome","display_name":"Diagnosis and treatment of irritable bowel syndrome","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W1965391982","doi":"https://doi.org/10.1358/dot.1998.34.7.484111","mag":"1965391982","pmid":"https://pubmed.ncbi.nlm.nih.gov/14988758"},"language":"en","primary_location":{"id":"doi:10.1358/dot.1998.34.7.484111","doi":"https://doi.org/10.1358/dot.1998.34.7.484111","is_oa":false,"landing_page_url":"https://doi.org/10.1358/dot.1998.34.7.484111","pdf_url":null,"source":{"id":"https://openalex.org/S202615048","display_name":"Drugs of today","issn_l":"0025-7656","issn":["0025-7656","1699-3993","1699-4019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4360969288","host_organization_name":"Prous Science","host_organization_lineage":["https://openalex.org/P4360969288"],"host_organization_lineage_names":["Prous Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drugs of Today","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103514732","display_name":"Chris B. Dalton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dalton, C.B.","raw_affiliation_strings":["Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7080, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7080, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022123400","display_name":"Douglas A. Drossman","orcid":"https://orcid.org/0000-0002-8178-0453","observed_orcids":["https://orcid.org/0000-0002-8178-0453"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Drossman, D.A.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.2688,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.87012522,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"34","issue":"7","first_page":"585","last_page":"585"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13289","display_name":"Infant Health and Development","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3611","display_name":"Pharmacy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10418","display_name":"Pelvic floor disorders treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/irritable-bowel-syndrome","display_name":"irritable bowel syndrome","score":1.0},{"id":"https://openalex.org/keywords/rome-criteria","display_name":"Rome criteria","score":0.925000011920929},{"id":"https://openalex.org/keywords/abdominal-pain","display_name":"abdominal pain","score":0.7879999876022339},{"id":"https://openalex.org/keywords/bowel-dysfunction","display_name":"bowel dysfunction","score":0.9950000047683716},{"id":"https://openalex.org/keywords/visceral-sensitivity","display_name":"visceral sensitivity","score":0.6290000081062317},{"id":"https://openalex.org/keywords/intestinal-motility","display_name":"intestinal motility","score":0.9200000166893005},{"id":"https://openalex.org/keywords/psychosocial-factors","display_name":"psychosocial factors","score":0.8610000014305115},{"id":"https://openalex.org/keywords/pathophysiology","display_name":"pathophysiology","score":0.6909999847412109},{"id":"https://openalex.org/keywords/ibs-treatment","display_name":"IBS treatment","score":0.6309999823570251},{"id":"https://openalex.org/keywords/behavioral-therapy","display_name":"behavior therapy","score":0.7089999914169312},{"id":"https://openalex.org/keywords/drug-therapy","display_name":"pharmacotherapy","score":0.699999988079071},{"id":"https://openalex.org/keywords/physician-patient-relationship","display_name":"physician-patient relationship","score":0.9319999814033508}],"concepts":[{"id":"https://openalex.org/C2778271842","wikidata":"https://www.wikidata.org/wiki/Q838966","display_name":"Irritable bowel syndrome","level":2,"score":0.9389364123344421},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9295767545700073},{"id":"https://openalex.org/C150966472","wikidata":"https://www.wikidata.org/wiki/Q3410145","display_name":"Psychosocial","level":2,"score":0.8151916265487671},{"id":"https://openalex.org/C2780955771","wikidata":"https://www.wikidata.org/wiki/Q183425","display_name":"Abdominal pain","level":2,"score":0.5826784372329712},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.500154972076416},{"id":"https://openalex.org/C2778188384","wikidata":"https://www.wikidata.org/wiki/Q5508825","display_name":"Functional gastrointestinal disorder","level":3,"score":0.4582618176937103},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.43579787015914917},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.4243919551372528},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3804408311843872},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.35607028007507324},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.34189099073410034}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1358/dot.1998.34.7.484111","doi":"https://doi.org/10.1358/dot.1998.34.7.484111","is_oa":false,"landing_page_url":"https://doi.org/10.1358/dot.1998.34.7.484111","pdf_url":null,"source":{"id":"https://openalex.org/S202615048","display_name":"Drugs of today","issn_l":"0025-7656","issn":["0025-7656","1699-3993","1699-4019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4360969288","host_organization_name":"Prous Science","host_organization_lineage":["https://openalex.org/P4360969288"],"host_organization_lineage_names":["Prous Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drugs of Today","raw_type":"journal-article"},{"id":"pmid:14988758","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14988758","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drugs of today (Barcelona, Spain : 1998)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.979200005531311,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3167877987","https://openalex.org/W2119217934","https://openalex.org/W2784553524","https://openalex.org/W2904392209","https://openalex.org/W1998382533","https://openalex.org/W2338576216","https://openalex.org/W1977913410","https://openalex.org/W2043462457","https://openalex.org/W2086182738","https://openalex.org/W1997204578"],"abstract_inverted_index":{"Irritable":[0],"bowel":[1,16],"syndrome":[2],"(IBS)":[3],"is":[4,19,33,68,120],"a":[5,94],"common":[6],"medical":[7],"disorder":[8],"characterized":[9],"by":[10,44,122],"symptoms":[11,134],"of":[12,39,55,59,125,132,138],"abdominal":[13],"pain":[14],"and":[15,24,52,63,86,102,112,116,130,135],"dysfunction.":[17],"It":[18],"associated":[20],"with":[21],"significant":[22],"disability":[23],"health":[25],"care":[26],"costs.":[27],"A":[28],"practical":[29],"approach":[30,118],"to":[31,48,71,81],"diagnosis":[32],"the":[34,49,56,73,99,123,126,128,133,136],"symptom-based":[35],"Rome":[36],"criteria.":[37],"Management":[38],"patients":[40],"has":[41],"been":[42],"helped":[43],"recent":[45],"findings":[46],"relating":[47],"epidemiology,":[50],"pathophysiology":[51],"psychosocial":[53],"contributions":[54],"disorder.":[57],"Dysregulation":[58],"intestinal":[60,84],"motor,":[61],"sensory":[62],"central":[64],"nervous":[65],"system":[66],"function":[67],"currently":[69],"believed":[70],"be":[72],"basis":[74],"for":[75],"IBS":[76],"symptoms.":[77],"Symptoms":[78],"are":[79,92],"due":[80],"both":[82],"abnormal":[83],"motility":[85],"enhanced":[87],"visceral":[88],"sensitivity.":[89],"Psychosocial":[90],"factors":[91],"not":[93],"cause":[95],"but":[96],"can":[97],"affect":[98],"illness":[100],"experience":[101],"clinical":[103],"outcome.":[104],"Finally,":[105],"treatment":[106],"involves":[107],"an":[108,113],"effective":[109],"physician-patient":[110],"relationship":[111],"integrated":[114],"pharmacologic":[115],"behavioral":[117],"that":[119],"determined":[121],"needs":[124],"patient,":[127],"type":[129],"severity":[131],"degree":[137],"disability.":[139]},"counts_by_year":[{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}