{"id":"https://openalex.org/W1965282002","doi":"https://doi.org/10.1007/s11103-008-9425-2","title":"The A622 gene in Nicotiana glauca (tree tobacco): evidence for a functional role in pyridine alkaloid synthesis","display_name":"The A622 gene in Nicotiana glauca (tree tobacco): evidence for a functional role in pyridine alkaloid synthesis","publication_year":2008,"publication_date":"2008-11-14","ids":{"openalex":"https://openalex.org/W1965282002","doi":"https://doi.org/10.1007/s11103-008-9425-2","mag":"1965282002","pmid":"https://pubmed.ncbi.nlm.nih.gov/19011764"},"language":"en","primary_location":{"id":"doi:10.1007/s11103-008-9425-2","doi":"https://doi.org/10.1007/s11103-008-9425-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11103-008-9425-2","pdf_url":null,"source":{"id":"https://openalex.org/S189846775","display_name":"Plant Molecular Biology","issn_l":"0167-4412","issn":["0167-4412","1573-5028"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Molecular Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084968444","display_name":"Kathleen DeBoer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Kathleen D. DeBoer","raw_affiliation_strings":["School of Biological Sciences, Monash University, Melbourne, VIC, 3800, Australia","Monash university"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences, Monash University, Melbourne, VIC, 3800, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Monash university","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056994767","display_name":"Jessica Lye","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jessica C. Lye","raw_affiliation_strings":["School of Biological Sciences, Monash University, Clayton Campus, Melbourne, VIC, 3800, Australia","Monash university"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences, Monash University, Clayton Campus, Melbourne, VIC, 3800, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Monash university","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039969914","display_name":"Campbell D. Aitken","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Campbell D. Aitken","raw_affiliation_strings":["School of Biological Sciences, Monash University, Clayton Campus, Melbourne, VIC, 3800, Australia","Monash university"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences, Monash University, Clayton Campus, Melbourne, VIC, 3800, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Monash university","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086150293","display_name":"Angela K.-K. Su","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Angela K.-K. Su","raw_affiliation_strings":["School of Biological Sciences, Monash University, Clayton Campus, Melbourne, VIC, 3800, Australia","Monash university"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences, Monash University, Clayton Campus, Melbourne, VIC, 3800, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Monash university","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113974820","display_name":"John D. Hamill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"John D. Hamill","raw_affiliation_strings":["School of Biological Sciences, Monash University, Clayton Campus, Melbourne, VIC, 3800, Australia","Monash university"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological Sciences, Monash University, Clayton Campus, Melbourne, VIC, 3800, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Monash university","institution_ids":["https://openalex.org/I56590836"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5113974820"],"corresponding_institution_ids":["https://openalex.org/I56590836"],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":null,"fwci":1.37,"has_fulltext":false,"cited_by_count":111,"citation_normalized_percentile":{"value":0.78198518,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"69","issue":"3","first_page":"299","last_page":"312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.7416999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.7416999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10240","display_name":"Plant tissue culture and regeneration","score":0.20569999516010284,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11237","display_name":"Plant Gene Expression Analysis","score":0.027499999850988388,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nicotiana-glauca","display_name":"Nicotiana glauca","score":0.9900000095367432},{"id":"https://openalex.org/keywords/anabasine","display_name":"anabasine","score":0.9940000176429749},{"id":"https://openalex.org/keywords/nicotine","display_name":"nicotine","score":0.9760000109672546},{"id":"https://openalex.org/keywords/nornicotine","display_name":"nornicotine","score":0.9679999947547913},{"id":"https://openalex.org/keywords/anatabine","display_name":"anatabine","score":0.9819999933242798},{"id":"https://openalex.org/keywords/rna-interference","display_name":"RNA interference","score":0.8029999732971191},{"id":"https://openalex.org/keywords/hairy-roots","display_name":"hairy roots","score":0.7689999938011169},{"id":"https://openalex.org/keywords/methyl-jasmonate","display_name":"methyl jasmonate","score":0.9120000004768372},{"id":"https://openalex.org/keywords/niacin","display_name":"nicotinic acid","score":0.9800000190734863}],"concepts":[{"id":"https://openalex.org/C2776975794","wikidata":"https://www.wikidata.org/wiki/Q419308","display_name":"Anabasine","level":3,"score":0.9903877973556519},{"id":"https://openalex.org/C2776166849","wikidata":"https://www.wikidata.org/wiki/Q907939","display_name":"Nornicotine","level":3,"score":0.9370402097702026},{"id":"https://openalex.org/C2778803642","wikidata":"https://www.wikidata.org/wiki/Q851829","display_name":"Nicotiana","level":4,"score":0.8818861842155457},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.761309802532196},{"id":"https://openalex.org/C2777942875","wikidata":"https://www.wikidata.org/wiki/Q26840883","display_name":"Methyl jasmonate","level":3,"score":0.6797280311584473},{"id":"https://openalex.org/C2777667214","wikidata":"https://www.wikidata.org/wiki/Q70702","display_name":"Alkaloid","level":2,"score":0.6694735288619995},{"id":"https://openalex.org/C2779547902","wikidata":"https://www.wikidata.org/wiki/Q28086552","display_name":"Nicotine","level":2,"score":0.5540850162506104},{"id":"https://openalex.org/C2781205006","wikidata":"https://www.wikidata.org/wiki/Q181095","display_name":"Nicotiana tabacum","level":3,"score":0.5212379097938538},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.45781034231185913},{"id":"https://openalex.org/C2776315051","wikidata":"https://www.wikidata.org/wiki/Q415713","display_name":"Jasmonate","level":5,"score":0.45178306102752686},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.4497499465942383},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4255329668521881},{"id":"https://openalex.org/C2778761015","wikidata":"https://www.wikidata.org/wiki/Q134172","display_name":"Solanaceae","level":3,"score":0.37850308418273926},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3180663287639618},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.14094790816307068},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.0},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000470","descriptor_name":"Alkaloids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009538","descriptor_name":"Nicotine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011725","descriptor_name":"Pyridines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014026","descriptor_name":"Nicotiana","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014026","descriptor_name":"Nicotiana","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11103-008-9425-2","doi":"https://doi.org/10.1007/s11103-008-9425-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11103-008-9425-2","pdf_url":null,"source":{"id":"https://openalex.org/S189846775","display_name":"Plant Molecular Biology","issn_l":"0167-4412","issn":["0167-4412","1573-5028"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Molecular Biology","raw_type":"journal-article"},{"id":"pmid:19011764","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19011764","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant molecular biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W43317203","https://openalex.org/W113521109","https://openalex.org/W277030014","https://openalex.org/W590276140","https://openalex.org/W1565824301","https://openalex.org/W1586750514","https://openalex.org/W1969690657","https://openalex.org/W1981087987","https://openalex.org/W1984012863","https://openalex.org/W1991914564","https://openalex.org/W1996059264","https://openalex.org/W1998961200","https://openalex.org/W2010630472","https://openalex.org/W2013381874","https://openalex.org/W2020643174","https://openalex.org/W2028903821","https://openalex.org/W2031510903","https://openalex.org/W2034175403","https://openalex.org/W2048898143","https://openalex.org/W2048962715","https://openalex.org/W2063401022","https://openalex.org/W2064831811","https://openalex.org/W2078185134","https://openalex.org/W2081483329","https://openalex.org/W2083928871","https://openalex.org/W2084609402","https://openalex.org/W2085492580","https://openalex.org/W2092986737","https://openalex.org/W2095995981","https://openalex.org/W2107086632","https://openalex.org/W2133626346","https://openalex.org/W2136121985","https://openalex.org/W2143791656","https://openalex.org/W2151934585","https://openalex.org/W2158094397","https://openalex.org/W2164887923","https://openalex.org/W2329793284","https://openalex.org/W3004487543"],"related_works":["https://openalex.org/W6927426700","https://openalex.org/W1975923250","https://openalex.org/W2136362003","https://openalex.org/W1967995859","https://openalex.org/W2062850767","https://openalex.org/W95664222","https://openalex.org/W170930178","https://openalex.org/W3015176171","https://openalex.org/W2032049916","https://openalex.org/W7098472186"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":15}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}