{"id":"https://openalex.org/W1965009089","doi":"https://doi.org/10.4088/pcc.v09n0301","title":"Characteristics and Course of Panic Disorder and Panic Disorder With Agoraphobia in Primary Care Patients","display_name":"Characteristics and Course of Panic Disorder and Panic Disorder With Agoraphobia in Primary Care Patients","publication_year":2007,"publication_date":"2007-06-15","ids":{"openalex":"https://openalex.org/W1965009089","doi":"https://doi.org/10.4088/pcc.v09n0301","mag":"1965009089","pmid":"https://pubmed.ncbi.nlm.nih.gov/17632648","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1911170"},"language":"en","primary_location":{"id":"doi:10.4088/pcc.v09n0301","doi":"https://doi.org/10.4088/pcc.v09n0301","is_oa":false,"landing_page_url":"https://doi.org/10.4088/pcc.v09n0301","pdf_url":null,"source":{"id":"https://openalex.org/S4210174730","display_name":"The Primary Care Companion to The Journal of Clinical Psychiatry","issn_l":"1523-5998","issn":["1523-5998","1537-6699","1555-211X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4322614534","host_organization_name":"Physicians Postgraduate Press, Inc.","host_organization_lineage":["https://openalex.org/P4322614534"],"host_organization_lineage_names":["Physicians Postgraduate Press, Inc."],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Primary Care Companion to The Journal of Clinical Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1911170","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111835862","display_name":"Jennifer Francis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I148314036","display_name":"Uniformed Services University of the Health Sciences","ror":"https://ror.org/04r3kq386","country_code":"US","type":"education","lineage":["https://openalex.org/I148314036"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer L. Francis","raw_affiliation_strings":["Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. jfrancis@usuhs.mil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. jfrancis@usuhs.mil","institution_ids":["https://openalex.org/I148314036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114862320","display_name":"Risa B. Wiesberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Risa B. Wiesberg","raw_affiliation_strings":["Brown University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brown University","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067960576","display_name":"INGRID R. DYCK","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ingrid R. Dyck","raw_affiliation_strings":["Brown University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brown University","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047943489","display_name":"Larry Culpepper","orcid":"https://orcid.org/0000-0002-7655-0477","observed_orcids":["https://orcid.org/0000-0002-7655-0477"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Larry Culpepper","raw_affiliation_strings":["Boston University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101802553","display_name":"Kevin W Smith","orcid":"https://orcid.org/0000-0002-7474-194X","observed_orcids":["https://orcid.org/0000-0002-7474-194X","https://orcid.org/0000-0002-9858-7713","https://orcid.org/0000-0003-4273-5999"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin Smith","raw_affiliation_strings":["Brown University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brown University","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046502349","display_name":"Maria Orlando Edelen","orcid":"https://orcid.org/0000-0002-1381-1465","observed_orcids":["https://orcid.org/0000-0002-1381-1465"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria Orlando Edelen","raw_affiliation_strings":["Brown University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brown University","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011774503","display_name":"Martin B Keller","orcid":"https://orcid.org/0000-0001-8977-6769","observed_orcids":["https://orcid.org/0000-0001-8977-6769"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin B. Keller","raw_affiliation_strings":["Brown University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brown University","institution_ids":["https://openalex.org/I27804330"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.801,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.74422777,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"09","issue":"03","first_page":"173","last_page":"179"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10272","display_name":"Mental Health Treatment and Access","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11093","display_name":"Personality Disorders and Psychopathology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/panic-disorder","display_name":"panic disorder","score":0.9980000257492065},{"id":"https://openalex.org/keywords/panic-disorder-with-agoraphobia","display_name":"panic disorder with agoraphobia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/clinical-course","display_name":"clinical course","score":0.7799999713897705},{"id":"https://openalex.org/keywords/recovery","display_name":"recovery","score":0.703000009059906},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.8130000233650208},{"id":"https://openalex.org/keywords/primary-care-patients","display_name":"primary care patients","score":0.7609999775886536},{"id":"https://openalex.org/keywords/major-depressive-disorder-comorbidity","display_name":"major depressive disorder comorbidity","score":0.9670000076293945},{"id":"https://openalex.org/keywords/psychosocial-interventions","display_name":"psychosocial interventions","score":0.9350000023841858},{"id":"https://openalex.org/keywords/treatment-bias","display_name":"treatment bias","score":0.6359999775886536},{"id":"https://openalex.org/keywords/global-assessment-of-functioning","display_name":"Global Assessment of Functioning","score":0.8080000281333923},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C2778678127","wikidata":"https://www.wikidata.org/wiki/Q174589","display_name":"Agoraphobia","level":4,"score":0.8827091455459595},{"id":"https://openalex.org/C2777529043","wikidata":"https://www.wikidata.org/wiki/Q741713","display_name":"Panic disorder","level":3,"score":0.8182358145713806},{"id":"https://openalex.org/C2984752397","wikidata":"https://www.wikidata.org/wiki/Q3259956","display_name":"Primary care","level":2,"score":0.6472203135490417},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5875495672225952},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.49020916223526},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.47661176323890686},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.27533596754074097},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.08405011892318726},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.4088/pcc.v09n0301","doi":"https://doi.org/10.4088/pcc.v09n0301","is_oa":false,"landing_page_url":"https://doi.org/10.4088/pcc.v09n0301","pdf_url":null,"source":{"id":"https://openalex.org/S4210174730","display_name":"The Primary Care Companion to The Journal of Clinical Psychiatry","issn_l":"1523-5998","issn":["1523-5998","1537-6699","1555-211X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4322614534","host_organization_name":"Physicians Postgraduate Press, Inc.","host_organization_lineage":["https://openalex.org/P4322614534"],"host_organization_lineage_names":["Physicians Postgraduate Press, Inc."],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Primary Care Companion to The Journal of Clinical Psychiatry","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:1191580","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1911170","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1911170","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1911170","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Prim Care Companion J Clin Psychiatry","raw_type":"Text"},{"id":"pmid:17632648","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17632648","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Primary care companion to the Journal of clinical psychiatry","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1191580","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1911170","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G3433488917","display_name":"Cognitive-behavioral Treatment of Anxiety/ Primary Care","funder_award_id":"K23MH069595","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"},{"id":"https://openalex.org/F4320307758","display_name":"Eli Lilly and Company","ror":"https://ror.org/01qat3289"},{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F4320307770","display_name":"AstraZeneca","ror":"https://ror.org/04r9x1a08"},{"id":"https://openalex.org/F4320307773","display_name":"GlaxoSmithKline","ror":"https://ror.org/01xsqw823"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W22895721","https://openalex.org/W40693701","https://openalex.org/W76376755","https://openalex.org/W107179074","https://openalex.org/W114654052","https://openalex.org/W1950704454","https://openalex.org/W1966460145","https://openalex.org/W1970077340","https://openalex.org/W1970952733","https://openalex.org/W1979264575","https://openalex.org/W1989845952","https://openalex.org/W2009773419","https://openalex.org/W2010024466","https://openalex.org/W2020344785","https://openalex.org/W2039245919","https://openalex.org/W2040445313","https://openalex.org/W2050456939","https://openalex.org/W2054395037","https://openalex.org/W2054953086","https://openalex.org/W2068632312","https://openalex.org/W2069078380","https://openalex.org/W2078721451","https://openalex.org/W2095500593","https://openalex.org/W2104142788","https://openalex.org/W2110100266","https://openalex.org/W2118225566","https://openalex.org/W2122910838","https://openalex.org/W2125171931","https://openalex.org/W2125457472","https://openalex.org/W2129336638","https://openalex.org/W2150127819","https://openalex.org/W2156254681","https://openalex.org/W2159061031","https://openalex.org/W2170921774","https://openalex.org/W2318179961","https://openalex.org/W2326713659","https://openalex.org/W2397491241","https://openalex.org/W2472195961","https://openalex.org/W2735928575","https://openalex.org/W4400406196"],"related_works":["https://openalex.org/W2031513547","https://openalex.org/W1986898180","https://openalex.org/W2033458079","https://openalex.org/W2113504544","https://openalex.org/W1970077340","https://openalex.org/W2406094304","https://openalex.org/W2077445998","https://openalex.org/W1992766292","https://openalex.org/W1505268445","https://openalex.org/W2111723397"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"examine":[2],"the":[3,36,107,123,210,236,251],"course":[4,223,252],"of":[5,109,149,189,224,239,253,264],"panic":[6,10,159],"disorder":[7,11,100,142,174],"(PD)":[8],"and":[9,33,50,56,59,67,79,155,170,178,196,204,241,260],"with":[12,77,83,86,103,202,218,228],"agoraphobia":[13],"(PDA)":[14],"in":[15,119,186,243,267],"235":[16],"primary":[17,29,244],"care":[18,30,216],"patients":[19,74,102,217],"during":[20],"a":[21,221,231],"3-year":[22,110],"period.":[23],"METHOD:":[24],"Patients":[25,85],"were":[26,43,75,81,88,127,164],"recruited":[27],"from":[28,98,132,168],"waiting":[31],"rooms":[32],"diagnosed":[34,76,82],"using":[35],"Structured":[37],"Clinical":[38],"Interview":[39],"for":[40,53,258,261],"DSM-IV.":[41],"They":[42],"reassessed":[44],"at":[45,106,158],"6":[46],"months,":[47],"1":[48],"year,":[49],"annually":[51],"thereafter":[52],"diagnosis,":[54],"treatment,":[55],"other":[57],"clinical":[58],"demographic":[60],"variables.":[61],"Recruitment":[62],"occurred":[63],"between":[64,122,193],"July":[65],"1997":[66],"May":[68],"2001.":[69],"RESULTS:":[70],"At":[71,137],"intake,":[72,138],"85":[73],"PD":[78,87,133,229,240],"150":[80],"PDA.":[84,190],"significantly":[89],"more":[90,128,232],"likely":[91,129,207],"to":[92,130,166,209,247,250],"achieve":[93],"recovery":[94,167,198],"(probability":[95],"estimate,":[96],"0.75)":[97],"their":[99],"than":[101],"PDA":[104,219,242],"(0.22)":[105],"end":[108],"follow-up":[111],"(p":[112,134,143,152,161,175,181],"<":[113],".0001).":[114],"There":[115],"was":[116],"no":[117],"difference":[118],"recurrence":[120],"rates":[121],"2":[124],"disorders.":[125],"Women":[126],"recover":[131],"=":[135,144,153,162,176,182],".001).":[136],"comorbid":[139,171],"generalized":[140],"anxiety":[141],".004),":[145],"higher":[146],"Global":[147],"Assessment":[148],"Functioning":[150],"score":[151],".0003),":[154],"older":[156],"age":[157],"onset":[160],".05)":[163,177],"related":[165],"PDA,":[169],"major":[172],"depressive":[173],"psychosocial":[179,194],"treatment":[180,195,211,265],".002)":[183],"predicted":[184],"remaining":[185],"an":[187],"episode":[188],"The":[191],"relationship":[192],"poor":[197],"must":[199],"be":[200],"interpreted":[201],"caution":[203],"is":[205,256],"most":[206],"due":[208],"bias":[212],"effect.":[213],"CONCLUSION:":[214],"Primary":[215],"have":[220,230],"chronic":[222],"illness,":[225],"whereas":[226],"those":[227],"relapsing":[233],"course.":[234],"Given":[235],"significant":[237],"burden":[238],"care,":[245],"attention":[246],"factors":[248],"relevant":[249],"these":[254],"disorders":[255],"important":[257],"recognition":[259],"continued":[262],"improvement":[263],"interventions":[266],"this":[268],"setting.":[269]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}