{"id":"https://openalex.org/W1964978604","doi":"https://doi.org/10.1016/j.gene.2011.10.017","title":"Effects of the calcium-sensing receptor A986S polymorphism on serum calcium and parathyroid hormone levels in healthy individuals: A meta-analysis","display_name":"Effects of the calcium-sensing receptor A986S polymorphism on serum calcium and parathyroid hormone levels in healthy individuals: A meta-analysis","publication_year":2011,"publication_date":"2011-10-18","ids":{"openalex":"https://openalex.org/W1964978604","doi":"https://doi.org/10.1016/j.gene.2011.10.017","mag":"1964978604","pmid":"https://pubmed.ncbi.nlm.nih.gov/22024717"},"language":"en","primary_location":{"id":"doi:10.1016/j.gene.2011.10.017","doi":"https://doi.org/10.1016/j.gene.2011.10.017","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.gene.2011.10.017","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064289105","display_name":"Yonghan He","orcid":"https://orcid.org/0000-0003-4409-4590","observed_orcids":["https://orcid.org/0000-0003-4409-4590"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yonghan He","raw_affiliation_strings":["Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023978408","display_name":"Liyuan Han","orcid":"https://orcid.org/0000-0001-9532-5622","observed_orcids":["https://orcid.org/0000-0001-9532-5622","https://orcid.org/0000-0002-3329-3212"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liyuan Han","raw_affiliation_strings":["Department of Social Medicine, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Social Medicine, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100320305","display_name":"Wen Li","orcid":"https://orcid.org/0000-0002-6807-479X","observed_orcids":["https://orcid.org/0000-0002-6807-479X","https://orcid.org/0000-0003-2402-6769"]},"institutions":[{"id":"https://openalex.org/I4210160452","display_name":"Third People's Hospital of Yunnan Province","ror":"https://ror.org/0555qme52","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160452"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wen Li","raw_affiliation_strings":["Department of Endocrinology, The Third People's Hospital of Yunnan Province, 292 Beijing Road, Guandu District, Kunming, Yunnan 650011, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, The Third People's Hospital of Yunnan Province, 292 Beijing Road, Guandu District, Kunming, Yunnan 650011, PR China","institution_ids":["https://openalex.org/I4210160452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058650746","display_name":"Xiang Shu","orcid":"https://orcid.org/0000-0002-4129-9403","observed_orcids":["https://orcid.org/0000-0002-4129-9403"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiang Shu","raw_affiliation_strings":["Department of Epidemiology, School of Public Health, University of Texas at Houston, 1200 Pressler St., TX 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, University of Texas at Houston, 1200 Pressler St., TX 77030, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chen Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen Zhao","raw_affiliation_strings":["Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ying He","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying He","raw_affiliation_strings":["Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009963211","display_name":"Mingxin Bi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingxin Bi","raw_affiliation_strings":["Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100601701","display_name":"Ying Li","orcid":"https://orcid.org/0000-0002-7595-2474","observed_orcids":["https://orcid.org/0000-0002-7595-2474"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ying Li","raw_affiliation_strings":["Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030009823","display_name":"Changhao Sun","orcid":"https://orcid.org/0000-0001-9416-7044","observed_orcids":["https://orcid.org/0000-0001-9416-7044","https://orcid.org/0000-0002-7651-2083"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Changhao Sun","raw_affiliation_strings":["Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, 150081, PR China","institution_ids":["https://openalex.org/I156144747"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5030009823","https://openalex.org/A5100601701"],"corresponding_institution_ids":["https://openalex.org/I156144747"],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":null,"fwci":0.2562,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.23300971,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"491","issue":"2","first_page":"110","last_page":"115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calcium-sensing-receptor","display_name":"calcium-sensing receptor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/serum-calcium","display_name":"serum calcium","score":0.8579999804496765},{"id":"https://openalex.org/keywords/ionized-calcium","display_name":"ionized calcium","score":0.9869999885559082},{"id":"https://openalex.org/keywords/parathyroid-hormone","display_name":"parathyroid hormone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/calcium-homeostasis","display_name":"calcium homeostasis","score":0.9879999756813049},{"id":"https://openalex.org/keywords/genetic-association","display_name":"genetic association","score":0.7149999737739563},{"id":"https://openalex.org/keywords/healthy-individuals","display_name":"healthy individuals","score":0.6259999871253967},{"id":"https://openalex.org/keywords/genotypes","display_name":"genotypes","score":0.6539999842643738}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9108825922012329},{"id":"https://openalex.org/C142590548","wikidata":"https://www.wikidata.org/wiki/Q417801","display_name":"Calcium-sensing receptor","level":4,"score":0.8684351444244385},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.7671700119972229},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.7171368598937988},{"id":"https://openalex.org/C149737253","wikidata":"https://www.wikidata.org/wiki/Q3240252","display_name":"Polymorphism (computer science)","level":4,"score":0.6004274487495422},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5738906264305115},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5424412488937378},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5286339521408081},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.4835667312145233},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.48315590620040894},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2903878092765808},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21727964282035828},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.1349608302116394},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010281","descriptor_name":"Parathyroid Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044169","descriptor_name":"Receptors, Calcium-Sensing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.gene.2011.10.017","doi":"https://doi.org/10.1016/j.gene.2011.10.017","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.gene.2011.10.017","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},{"id":"pmid:22024717","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22024717","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.75,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W279604917","https://openalex.org/W1967046314","https://openalex.org/W1973882005","https://openalex.org/W1975367389","https://openalex.org/W1988537358","https://openalex.org/W1993799188","https://openalex.org/W1996116102","https://openalex.org/W2005675355","https://openalex.org/W2009441758","https://openalex.org/W2027600559","https://openalex.org/W2051708905","https://openalex.org/W2051733746","https://openalex.org/W2070426370","https://openalex.org/W2078643685","https://openalex.org/W2102531115","https://openalex.org/W2106856165","https://openalex.org/W2117403606","https://openalex.org/W2122514015","https://openalex.org/W2126930838","https://openalex.org/W2137070340","https://openalex.org/W2145930493","https://openalex.org/W2153942663","https://openalex.org/W2155360150","https://openalex.org/W2157138210","https://openalex.org/W2157823046","https://openalex.org/W2162462842","https://openalex.org/W2162545344","https://openalex.org/W2163675908","https://openalex.org/W2316186137","https://openalex.org/W2326971455","https://openalex.org/W2374559408","https://openalex.org/W4229920882"],"related_works":["https://openalex.org/W2005675355","https://openalex.org/W2051708905","https://openalex.org/W2019246352","https://openalex.org/W2117403606","https://openalex.org/W2054836407","https://openalex.org/W3030421128","https://openalex.org/W2074351728","https://openalex.org/W4312650326","https://openalex.org/W2307785090","https://openalex.org/W3129002148"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}