{"id":"https://openalex.org/W1964784393","doi":"https://doi.org/10.1159/000108994","title":"Pure Subcortical Arteriosclerotic Encephalopathy (Binswanger\u2019s Disease): A Clinicopathologic Study","display_name":"Pure Subcortical Arteriosclerotic Encephalopathy (Binswanger\u2019s Disease): A Clinicopathologic Study","publication_year":1992,"publication_date":"1992-04-08","ids":{"openalex":"https://openalex.org/W1964784393","doi":"https://doi.org/10.1159/000108994","mag":"1964784393"},"language":"en","primary_location":{"id":"doi:10.1159/000108994","doi":"https://doi.org/10.1159/000108994","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000108994","pdf_url":null,"source":{"id":"https://openalex.org/S43436036","display_name":"Cerebrovascular Diseases","issn_l":"1015-9770","issn":["1015-9770","1421-9786"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cerebrovascular Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047700818","display_name":"Kent A. Fredriksson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Fredriksson","raw_affiliation_strings":["Neurology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111789565","display_name":"A. Brun","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Brun","raw_affiliation_strings":["Pathology, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology, and","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109317396","display_name":"Lars Gustafson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"L. Gustafson","raw_affiliation_strings":["Psychogeriatrics, University of Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychogeriatrics, University of Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9312,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.85099264,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":"82","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13648","display_name":"Cerebrovascular and genetic disorders","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13648","display_name":"Cerebrovascular and genetic disorders","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/binswanger-disease","display_name":"Binswanger disease","score":0.7870000004768372},{"id":"https://openalex.org/keywords/subcortical-arteriosclerotic-encephalopathy","display_name":"subcortical arteriosclerotic encephalopathy","score":0.9729999899864197},{"id":"https://openalex.org/keywords/lacunar-infarction","display_name":"lacunar infarction","score":0.7129999995231628},{"id":"https://openalex.org/keywords/chronic-hypertension","display_name":"chronic hypertension","score":0.7269999980926514},{"id":"https://openalex.org/keywords/cerebral-blood-flow-reduction","display_name":"cerebral blood flow reduction","score":0.8009999990463257},{"id":"https://openalex.org/keywords/dementia","display_name":"dementia","score":0.847000002861023},{"id":"https://openalex.org/keywords/gait-disturbance","display_name":"gait disturbance","score":0.593999981880188},{"id":"https://openalex.org/keywords/pseudobulbar-palsy","display_name":"pseudobulbar palsy","score":0.9210000038146973},{"id":"https://openalex.org/keywords/urinary-incontinence","display_name":"urinary incontinence","score":0.9789999723434448},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.48100000619888306},{"id":"https://openalex.org/keywords/clinicopathological-correlation","display_name":"clinicopathological correlation","score":0.9049999713897705}],"concepts":[{"id":"https://openalex.org/C2779710473","wikidata":"https://www.wikidata.org/wiki/Q1815985","display_name":"Pseudobulbar palsy","level":2,"score":0.8607262372970581},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8431199789047241},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.6380940675735474},{"id":"https://openalex.org/C2779949217","wikidata":"https://www.wikidata.org/wiki/Q4138746","display_name":"Hypertensive encephalopathy","level":3,"score":0.6308561563491821},{"id":"https://openalex.org/C2778621155","wikidata":"https://www.wikidata.org/wiki/Q576349","display_name":"Encephalopathy","level":2,"score":0.4958361089229584},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.49331918358802795},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.4308604896068573},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.40930265188217163},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3713567852973938},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.3205113410949707},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2897927463054657}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1159/000108994","doi":"https://doi.org/10.1159/000108994","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000108994","pdf_url":null,"source":{"id":"https://openalex.org/S43436036","display_name":"Cerebrovascular Diseases","issn_l":"1015-9770","issn":["1015-9770","1421-9786"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cerebrovascular Diseases","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2089502153","https://openalex.org/W2396169761","https://openalex.org/W2302454856","https://openalex.org/W1979335911","https://openalex.org/W7052654","https://openalex.org/W2395018397","https://openalex.org/W1987493965","https://openalex.org/W2460221012","https://openalex.org/W2034050211","https://openalex.org/W2412614768"],"abstract_inverted_index":{"We":[0,109],"studied":[1],"14":[2],"cases":[3,31],"of":[4,37,93,114],"pure":[5,101],"subcortical":[6,129],"arteriosclerotic":[7,130],"encephalopathy":[8],"selected":[9],"from":[10,33],"the":[11,22,65],"autopsy":[12],"files":[13],"(c.f.":[14],"part":[15],"2)":[16],"in":[17,64,73,122],"order":[18],"to":[19,128],"single":[20],"out":[21],"characteristic":[23],"clinical":[24],"features":[25],"(average":[26],"age:":[27],"80.9":[28],"years).":[29],"Nine":[30],"were":[32],"a":[34,60],"prospective":[35],"study":[36],"dementia.":[38],"The":[39,46],"longest":[40],"observation":[41],"time":[42],"was":[43],"18":[44],"years.":[45],"main":[47],"findings":[48],"were:":[49],"(i)":[50],"previous":[51],"chronic":[52],"hypertension,":[53],"variable":[54],"and":[55,59,91,107,116],"declining":[56],"blood":[57,75],"pressure":[58],"high":[61],"ischemic":[62],"score":[63],"late":[66],"symptomatic":[67],"phase;":[68],"(ii)":[69],"bilateral":[70],"multifocal":[71],"decreases":[72],"cerebral":[74],"flow;":[76],"(iii)":[77],"gradually":[78],"progressive,":[79],"fluctuating":[80],"mental":[81],"changes":[82],"(forgetfulness,":[83],"abulia,":[84],"emotional":[85],"lability,":[86],"impaired":[87],"higher":[88],"cortical":[89],"functions)":[90],"disorders":[92,113],"motility":[94,117],"(small-stepped":[95],"gait,":[96],"pseudobulbar":[97],"palsy,":[98],"urinary":[99],"incontinence),":[100],"motor":[102],"strokes,":[103],"with":[104,119],"later":[105],"dementia":[106],"immobility.":[108],"conclude":[110],"that":[111],"insidious":[112],"mentation":[115],"combined":[118],"lacunar":[120],"strokes":[121],"elderly":[123],"individuals":[124],"are":[125],"diagnostic":[126],"clues":[127],"encephalopathy.":[131]},"counts_by_year":[{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}