{"id":"https://openalex.org/W1964580716","doi":"https://doi.org/10.4254/wjh.v7.i2.276","title":"Post-transplantation hepatocellular carcinoma recurrence: Patterns and relation between vascularity and differentiation degree","display_name":"Post-transplantation hepatocellular carcinoma recurrence: Patterns and relation between vascularity and differentiation degree","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W1964580716","doi":"https://doi.org/10.4254/wjh.v7.i2.276","mag":"1964580716","pmid":"https://pubmed.ncbi.nlm.nih.gov/25729483","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4342610"},"language":"en","primary_location":{"id":"doi:10.4254/wjh.v7.i2.276","doi":"https://doi.org/10.4254/wjh.v7.i2.276","is_oa":true,"landing_page_url":"https://doi.org/10.4254/wjh.v7.i2.276","pdf_url":"https://www.wjgnet.com/1948-5182/full/v7/i2/276.htm","source":{"id":"https://openalex.org/S156266972","display_name":"World Journal of Hepatology","issn_l":"1948-5182","issn":["1948-5182"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315735","host_organization_name":"Baishideng Publishing Group","host_organization_lineage":["https://openalex.org/P4310315735"],"host_organization_lineage_names":["Baishideng Publishing Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Hepatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.wjgnet.com/1948-5182/full/v7/i2/276.htm","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004060360","display_name":"Annarita Pecchi","orcid":"https://orcid.org/0000-0001-8142-3256","observed_orcids":["https://orcid.org/0000-0001-8142-3256"]},"institutions":[{"id":"https://openalex.org/I4210109058","display_name":"Azienda Ospedaliero-Universitaria di Modena","ror":"https://ror.org/01hmmsr16","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210109058"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Annarita Pecchi","raw_affiliation_strings":["Annarita Pecchi, Giulia Besutti, Mario De Santis, Pietro Torricelli, Dipartimento di Diagnostica per Immagini, Azienda Ospedaliero-Universitaria Policlinico di Modena, 41124 Modena, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Annarita Pecchi, Giulia Besutti, Mario De Santis, Pietro Torricelli, Dipartimento di Diagnostica per Immagini, Azienda Ospedaliero-Universitaria Policlinico di Modena, 41124 Modena, Italy","institution_ids":["https://openalex.org/I4210109058"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5004060360"],"corresponding_institution_ids":["https://openalex.org/I4210109058"],"apc_list":null,"apc_paid":null,"fwci":1.6753,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.83750696,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"7","issue":"2","first_page":"276","last_page":"276"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.9929999709129333},{"id":"https://openalex.org/keywords/liver-transplantation","display_name":"liver transplantation","score":0.8870000243186951},{"id":"https://openalex.org/keywords/tumor-vascularity","display_name":"tumor vascularity","score":0.9660000205039978},{"id":"https://openalex.org/keywords/tumor-grade","display_name":"tumor grade","score":0.7390000224113464},{"id":"https://openalex.org/keywords/hypervascular-tumor","display_name":"hypervascular tumor","score":0.7289999723434448},{"id":"https://openalex.org/keywords/hypovascular-tumor","display_name":"hypovascular tumor","score":0.8809999823570251},{"id":"https://openalex.org/keywords/intrahepatic-recurrence","display_name":"intrahepatic recurrence","score":0.7390000224113464},{"id":"https://openalex.org/keywords/extrahepatic-recurrence","display_name":"extrahepatic recurrence","score":0.9729999899864197},{"id":"https://openalex.org/keywords/recurrence-patterns","display_name":"recurrence patterns","score":0.6620000004768372},{"id":"https://openalex.org/keywords/histopathological-grade","display_name":"histopathological grade","score":0.47600001096725464},{"id":"https://openalex.org/keywords/dynamic-contrast-enhanced-imaging","display_name":"dynamic contrast-enhanced imaging","score":0.5720000267028809},{"id":"https://openalex.org/keywords/time-to-recurrence","display_name":"time to recurrence","score":0.4779999852180481},{"id":"https://openalex.org/keywords/recurrence-rate","display_name":"recurrence rate","score":0.41999998688697815},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.6079999804496765}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.935865044593811},{"id":"https://openalex.org/C178596483","wikidata":"https://www.wikidata.org/wiki/Q7916472","display_name":"Vascularity","level":2,"score":0.9046039581298828},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.8440999984741211},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.6952212452888489},{"id":"https://openalex.org/C2779609443","wikidata":"https://www.wikidata.org/wiki/Q1368191","display_name":"Liver transplantation","level":3,"score":0.6670752167701721},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6232631206512451},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5904891490936279},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5069558620452881},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.49636346101760864},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3683788478374481},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2569514513015747}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.4254/wjh.v7.i2.276","doi":"https://doi.org/10.4254/wjh.v7.i2.276","is_oa":true,"landing_page_url":"https://doi.org/10.4254/wjh.v7.i2.276","pdf_url":"https://www.wjgnet.com/1948-5182/full/v7/i2/276.htm","source":{"id":"https://openalex.org/S156266972","display_name":"World Journal of Hepatology","issn_l":"1948-5182","issn":["1948-5182"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315735","host_organization_name":"Baishideng Publishing Group","host_organization_lineage":["https://openalex.org/P4310315735"],"host_organization_lineage_names":["Baishideng Publishing Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Hepatology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3305961","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4342610","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4342610","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4342610","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World J Hepatol","raw_type":"Text"},{"id":"pmid:25729483","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25729483","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World journal of hepatology","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unimore.it:11380/1141604","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11380/1141604","pdf_url":"https://iris.unimore.it/bitstream/11380/1141604/2/1141604.pdf","source":{"id":"https://openalex.org/S4306400718","display_name":"IRIS UNIMORE (University of Modena and Reggio Emilia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I122346577","host_organization_name":"University of Modena and Reggio Emilia","host_organization_lineage":["https://openalex.org/I122346577"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:3150032634","doi":null,"is_oa":true,"landing_page_url":"http://www.cqvip.com/QK/71422X/201502/664257906.html","pdf_url":null,"source":{"id":"https://openalex.org/S156266972","display_name":"World Journal of Hepatology","issn_l":"1948-5182","issn":["1948-5182"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315735","host_organization_name":"Baishideng Publishing Group","host_organization_lineage":["https://openalex.org/P4310315735"],"host_organization_lineage_names":["Baishideng Publishing Group"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u4e16\u754c\u809d\u75c5\u5b66\u6742\u5fd7\uff1a\u82f1\u6587\u7248\uff08\u7535\u5b50\u7248\uff09","raw_type":null}],"best_oa_location":{"id":"doi:10.4254/wjh.v7.i2.276","doi":"https://doi.org/10.4254/wjh.v7.i2.276","is_oa":true,"landing_page_url":"https://doi.org/10.4254/wjh.v7.i2.276","pdf_url":"https://www.wjgnet.com/1948-5182/full/v7/i2/276.htm","source":{"id":"https://openalex.org/S156266972","display_name":"World Journal of Hepatology","issn_l":"1948-5182","issn":["1948-5182"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315735","host_organization_name":"Baishideng Publishing Group","host_organization_lineage":["https://openalex.org/P4310315735"],"host_organization_lineage_names":["Baishideng Publishing Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Hepatology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1964580716.pdf","grobid_xml":"https://content.openalex.org/works/W1964580716.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1971085576","https://openalex.org/W1973670709","https://openalex.org/W1976082980","https://openalex.org/W1985922618","https://openalex.org/W1997621788","https://openalex.org/W2005883921","https://openalex.org/W2008086929","https://openalex.org/W2016399542","https://openalex.org/W2021805276","https://openalex.org/W2034194162","https://openalex.org/W2054191909","https://openalex.org/W2056082672","https://openalex.org/W2068153949","https://openalex.org/W2075030663","https://openalex.org/W2080044996","https://openalex.org/W2103310685","https://openalex.org/W2122337982","https://openalex.org/W2147735490","https://openalex.org/W2157921636","https://openalex.org/W2163486683","https://openalex.org/W2167460551","https://openalex.org/W2312913562","https://openalex.org/W2315027248","https://openalex.org/W2597872842"],"related_works":["https://openalex.org/W182547294","https://openalex.org/W2501538652","https://openalex.org/W4292608275","https://openalex.org/W1985497196","https://openalex.org/W4307553490","https://openalex.org/W7215591038","https://openalex.org/W2745318257","https://openalex.org/W2028975947","https://openalex.org/W2484596965","https://openalex.org/W2083124691"],"abstract_inverted_index":{"AIM:":[0],"To":[1],"evaluate":[2],"the":[3,83,106,171,190,194,200,211,216,235,244,267,314,317,349,354,400,403],"relationship":[4],"between":[5,96,189,202,282,348,378,388,399],"hepatocellular":[6],"carcinoma":[7],"(HCC)":[8],"vascularity":[9,284],"and":[10,15,69,100,113,126,136,149,152,155,170,186,193,199,204,229,260,285,331,334,353,380,391,402],"grade;":[11],"to":[12,370],"describe":[13],"patterns":[14],"vascular/histopathological":[16],"variations":[17,181,206],"of":[18,74,82,120,129,180,222,240,316,365,395],"post-transplantation":[19],"recurrence.":[20,121],"METHODS:":[21],"This":[22],"retrospective":[23],"study":[24],"included":[25],"165":[26],"patients":[27,218,237,275,301,309,324,329,338,341],"(143":[28],"men,":[29],"22":[30],"women;":[31],"median":[32],"age":[33],"56.8":[34],"years,":[35],"range":[36],"28-70.4":[37],"years)":[38],"transplanted":[39],"for":[40,118,273],"HCC":[41,63,91,351,357,389],"who":[42,302],"had":[43,227,249,303,342,362],"a":[44,304,343,363],"follow-up":[45,111],"period":[46],"longer":[47],"than":[48],"2":[49,145],"mo.":[50],"Pre-transplantation":[51],"dynamic":[52],"computed":[53],"tomography":[54],"or":[55,143,168],"magnetic":[56],"resonance":[57],"examinations":[58],"were":[59,86,116,132,164],"retrospectively":[60],"reviewed,":[61,87],"classifying":[62,134],"imaging":[64,97,114,127,183,203,220,283,346,379],"enhancement":[65,184],"pattern":[66,99,185],"into":[67],"hypervascular":[68,167,228,305],"hypovascular":[70,169,232],"based":[71,139,158],"on":[72,140,159],"presence":[73,179],"wash-in":[75],"during":[76],"arterial":[77],"phase.":[78],"All":[79,110,161,297],"pathologic":[80],"reports":[81],"explanted":[84,245],"livers":[85],"collecting":[88],"data":[89,115],"about":[90],"differentiation":[92,172,268],"degree.":[93],"The":[94,178],"association":[95,201,279,375],"vascular":[98],"pathological":[101,187,286],"grade":[102,188,250,254,258,263,287,390],"was":[103,124,174,197,207,270,280,294,320,376,386],"estimated":[104,208],"using":[105,210],"Fisher":[107],"exact":[108],"test.":[109,213],"clinical":[112],"reviewed":[117],"evidence":[119,221,239],"Recurrence":[122],"rate":[123,293],"calculated":[125],"features":[128],"recurrent":[130,356],"tumor":[131,192,242],"collected,":[133],"early":[135],"late":[137,312],"recurrences":[138,157,163,298],"timing":[141],"(<":[142],"\u2265":[144],"years":[146],"after":[147],"transplantation)":[148],"intrahepatic,":[150],"extrahepatic":[151,156,321,335],"both":[153,332],"intrahepatic":[154,162,195,326,333,355],"location.":[160],"classified":[165],"as":[166],"degree":[173,269,394],"collected":[175],"where":[176],"available.":[177],"in":[182,243,300,322,327,336,345],"primary":[191,306,350,401],"recurrence":[196,292,319,404],"evaluated":[198],"histopatholgical":[205],"by":[209],"\u03c7(2)":[212],"RESULTS:":[214],"Of":[215],"163":[217],"with":[219,238],"viable":[223,241],"tumor,":[224],"156":[225],"(95.7%)":[226],"7":[230,328],"(4.3%)":[231],"HCC.":[233],"Among":[234],"125":[236],"liver,":[246],"19":[247],"(15.2%)":[248],"1,":[251],"56":[252],"(44.8%)":[253],"2,":[255],"40":[256],"(32%)":[257],"3":[259,337],"4":[261,264],"(3.2%)":[262],"HCC,":[265],"while":[266,359],"not":[271,408],"assessable":[272],"6":[274],"(4.8%).":[276],"A":[277,384],"significant":[278],"found":[281,377,387],"(P":[288],"=":[289],"0.035).":[290],"Post-transplantation":[291],"14.55%":[295],"(24/165).":[296],"occurred":[299],"tumor.":[307],"Three":[308],"(12.5%)":[310],"experienced":[311],"recurrence;":[313],"location":[315],"first":[318],"14":[323],"(58.3%),":[325],"(29.2%)":[330],"(12.5%).":[339],"Two":[340],"variation":[344,364],"characteristics":[347,367],"(hypervascular)":[352],"(hypovascular),":[358],"1":[360],"patient":[361],"histopathological":[366,381],"(from":[368],"moderate":[369],"poor":[371],"differentiation),":[372],"however":[373],"no":[374],"variations.":[382],"CONCLUSION:":[383],"correlation":[385],"vascularity;":[392],"some":[393],"variability":[396],"may":[397],"exist":[398],"imaging/histopathological":[405],"characteristics,":[406],"apparently":[407],"correlated.":[409]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}