{"id":"https://openalex.org/W1964569622","doi":"https://doi.org/10.1007/bf01875426","title":"Mechanisms of cation permeation across apical cell membrane ofNecturus gallbladder: Effects of luminal pH and divalent cations on K+ and Na+ permeability","display_name":"Mechanisms of cation permeation across apical cell membrane ofNecturus gallbladder: Effects of luminal pH and divalent cations on K+ and Na+ permeability","publication_year":1981,"publication_date":"1981-10-01","ids":{"openalex":"https://openalex.org/W1964569622","doi":"https://doi.org/10.1007/bf01875426","mag":"1964569622","pmid":"https://pubmed.ncbi.nlm.nih.gov/7241581"},"language":"en","primary_location":{"id":"doi:10.1007/bf01875426","doi":"https://doi.org/10.1007/bf01875426","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf01875426","pdf_url":null,"source":{"id":"https://openalex.org/S967762373","display_name":"The Journal of Membrane Biology","issn_l":"0022-2631","issn":["0022-2631","1432-1424"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Membrane Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005104920","display_name":"Luis Reuss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luis Reuss","raw_affiliation_strings":["Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, 63110, St. Louis, Missouri","Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, St. Louis,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, 63110, St. Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, St. Louis,","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111675997","display_name":"Laurence Y. Cheung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurence Y. Cheung","raw_affiliation_strings":["Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, 63110, St. Louis, Missouri","Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, St. Louis,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, 63110, St. Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, St. Louis,","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065782570","display_name":"Timothy P. Grady","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy P. Grady","raw_affiliation_strings":["Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, 63110, St. Louis, Missouri","Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, St. Louis,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, 63110, St. Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Physiology and Biophysics and Department of Surgery, Washington University School of Medicine, St. Louis,","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":null,"fwci":4.0577,"has_fulltext":false,"cited_by_count":64,"citation_normalized_percentile":{"value":0.94706566,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"59","issue":"3","first_page":"211","last_page":"224"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.7304999828338623,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.7304999828338623,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.26269999146461487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11480","display_name":"Connexins and lens biology","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cation-permeability","display_name":"cation permeability","score":0.7730000019073486},{"id":"https://openalex.org/keywords/apical-membrane","display_name":"apical membrane","score":0.9089999794960022},{"id":"https://openalex.org/keywords/luminal-ph","display_name":"luminal pH","score":0.9570000171661377},{"id":"https://openalex.org/keywords/divalent-cations","display_name":"divalent cations","score":0.9020000100135803},{"id":"https://openalex.org/keywords/potassium-permeability","display_name":"potassium permeability","score":0.9750000238418579},{"id":"https://openalex.org/keywords/sodium-permeability","display_name":"sodium permeability","score":0.9990000128746033},{"id":"https://openalex.org/keywords/membrane-depolarization","display_name":"membrane depolarization","score":0.8809999823570251},{"id":"https://openalex.org/keywords/membrane-hyperpolarization","display_name":"membrane hyperpolarization","score":0.796999990940094},{"id":"https://openalex.org/keywords/transepithelial-electrical-resistance","display_name":"transepithelial electrical resistance","score":0.8510000109672546},{"id":"https://openalex.org/keywords/membrane-potential","display_name":"membrane potential","score":0.4490000009536743},{"id":"https://openalex.org/keywords/barium","display_name":"barium","score":0.6010000109672546},{"id":"https://openalex.org/keywords/strontium","display_name":"strontium","score":1.0},{"id":"https://openalex.org/keywords/magnesium","display_name":"magnesium","score":0.4659999907016754},{"id":"https://openalex.org/keywords/calcium","display_name":"calcium","score":0.9990000128746033},{"id":"https://openalex.org/keywords/potassium-secretion","display_name":"potassium secretion","score":0.5080000162124634},{"id":"https://openalex.org/keywords/renal-tubules","display_name":"renal tubules","score":0.8889999985694885},{"id":"https://openalex.org/keywords/potassium-channels","display_name":"potassium channels","score":0.5569999814033508}],"concepts":[{"id":"https://openalex.org/C74884574","wikidata":"https://www.wikidata.org/wiki/Q171407","display_name":"Divalent","level":2,"score":0.8700242042541504},{"id":"https://openalex.org/C50670333","wikidata":"https://www.wikidata.org/wiki/Q907651","display_name":"Permeation","level":3,"score":0.7504931092262268},{"id":"https://openalex.org/C120882062","wikidata":"https://www.wikidata.org/wiki/Q28352","display_name":"Permeability (electromagnetism)","level":3,"score":0.6473785638809204},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6113110184669495},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5356649160385132},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.5025243759155273},{"id":"https://openalex.org/C2994297994","wikidata":"https://www.wikidata.org/wiki/Q866317","display_name":"Cell permeability","level":2,"score":0.43522652983665466},{"id":"https://openalex.org/C2777148285","wikidata":"https://www.wikidata.org/wiki/Q64386","display_name":"Gallbladder","level":2,"score":0.4267193377017975},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.33466506004333496},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2652806043624878},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14220011234283447},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12702035903930664},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.06770223379135132},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06370440125465393}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002412","descriptor_name":"Cations","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002413","descriptor_name":"Cations, Divalent","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002463","descriptor_name":"Cell Membrane Permeability","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004553","descriptor_name":"Electric Conductivity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005704","descriptor_name":"Gallbladder","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008564","descriptor_name":"Membrane Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009337","descriptor_name":"Necturus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009994","descriptor_name":"Osmolar Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011188","descriptor_name":"Potassium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012964","descriptor_name":"Sodium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf01875426","doi":"https://doi.org/10.1007/bf01875426","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf01875426","pdf_url":null,"source":{"id":"https://openalex.org/S967762373","display_name":"The Journal of Membrane Biology","issn_l":"0022-2631","issn":["0022-2631","1432-1424"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Membrane Biology","raw_type":"journal-article"},{"id":"pmid:7241581","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7241581","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of membrane biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1554740034","https://openalex.org/W1968085309","https://openalex.org/W1973828738","https://openalex.org/W1982456678","https://openalex.org/W1983829684","https://openalex.org/W1999786119","https://openalex.org/W2003003393","https://openalex.org/W2012906347","https://openalex.org/W2013503683","https://openalex.org/W2029046717","https://openalex.org/W2045084108","https://openalex.org/W2052553582","https://openalex.org/W2060688140","https://openalex.org/W2062507442","https://openalex.org/W2063324203","https://openalex.org/W2073176501","https://openalex.org/W2076764566","https://openalex.org/W2077438161","https://openalex.org/W2120003464","https://openalex.org/W2126914983","https://openalex.org/W2138067074","https://openalex.org/W2159828330","https://openalex.org/W2239171240","https://openalex.org/W2341191003","https://openalex.org/W2431602000","https://openalex.org/W2887216180","https://openalex.org/W2887759052","https://openalex.org/W3185889544"],"related_works":["https://openalex.org/W2190530020","https://openalex.org/W1977329530","https://openalex.org/W2058551605","https://openalex.org/W1995508882","https://openalex.org/W2029046717","https://openalex.org/W7096365559","https://openalex.org/W2414480570","https://openalex.org/W2000795113","https://openalex.org/W1554740034","https://openalex.org/W2063494381"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}