{"id":"https://openalex.org/W1964567249","doi":"https://doi.org/10.1038/nature10195","title":"Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein","display_name":"Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein","publication_year":2011,"publication_date":"2011-06-01","ids":{"openalex":"https://openalex.org/W1964567249","doi":"https://doi.org/10.1038/nature10195","mag":"1964567249","pmid":"https://pubmed.ncbi.nlm.nih.gov/21720370","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3179858"},"language":"en","primary_location":{"id":"doi:10.1038/nature10195","doi":"https://doi.org/10.1038/nature10195","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nature10195","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3179858","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089559564","display_name":"Kasia Hrecka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kasia Hrecka","raw_affiliation_strings":["Department of Molecular Biology and Microbiology, Case School of Medicine, Cleveland, Ohio 44106, USA","Department of Molecular Biology and Microbiology, Case School of Medicine, Cleveland, 44106, Ohio, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology and Microbiology, Case School of Medicine, Cleveland, Ohio 44106, USA","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Department of Molecular Biology and Microbiology, Case School of Medicine, Cleveland, 44106, Ohio, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034665741","display_name":"Caili Hao","orcid":"https://orcid.org/0009-0006-6743-6222","observed_orcids":["https://orcid.org/0009-0006-6743-6222"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caili Hao","raw_affiliation_strings":["Department of Molecular Biology and Microbiology, Case School of Medicine, Cleveland, 44106, Ohio, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology and Microbiology, Case School of Medicine, Cleveland, 44106, Ohio, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019869268","display_name":"Magda Gierszewska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Magda Gierszewska","raw_affiliation_strings":["Cold Spring Harbor Laboratory, Cold Spring Harbor, 11724, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, Cold Spring Harbor, 11724, New York, USA","institution_ids":["https://openalex.org/I2750212522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086228456","display_name":"Selene K. Swanson","orcid":"https://orcid.org/0000-0002-2461-2744","observed_orcids":["https://orcid.org/0000-0002-2461-2744"]},"institutions":[{"id":"https://openalex.org/I114131015","display_name":"Stowers Institute for Medical Research","ror":"https://ror.org/04bgfm609","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I114131015"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Selene K. Swanson","raw_affiliation_strings":["Stowers Institute for Medical Research, Kansas City, 64110, Missouri, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stowers Institute for Medical Research, Kansas City, 64110, Missouri, USA","institution_ids":["https://openalex.org/I114131015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021385293","display_name":"Ma\u0142gorzata K\u0119sik-Brodacka","orcid":"https://orcid.org/0000-0003-1363-7986","observed_orcids":["https://orcid.org/0000-0003-1363-7986"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Malgorzata Kesik-Brodacka","raw_affiliation_strings":["Department of Molecular Biology and Microbiology, Case School of Medicine, Cleveland, 44106, Ohio, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology and Microbiology, Case School of Medicine, Cleveland, 44106, Ohio, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Smita Srivastava","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Smita Srivastava","raw_affiliation_strings":["Cold Spring Harbor Laboratory, Cold Spring Harbor, 11724, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, Cold Spring Harbor, 11724, New York, USA","institution_ids":["https://openalex.org/I2750212522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079392980","display_name":"Laurence A. Florens","orcid":"https://orcid.org/0000-0002-9310-6650","observed_orcids":["https://orcid.org/0000-0002-9310-6650"]},"institutions":[{"id":"https://openalex.org/I114131015","display_name":"Stowers Institute for Medical Research","ror":"https://ror.org/04bgfm609","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I114131015"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurence Florens","raw_affiliation_strings":["Stowers Institute for Medical Research, Kansas City, 64110, Missouri, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stowers Institute for Medical Research, Kansas City, 64110, Missouri, USA","institution_ids":["https://openalex.org/I114131015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034566006","display_name":"Michael P. Washburn","orcid":"https://orcid.org/0000-0001-7568-2585","observed_orcids":["https://orcid.org/0000-0001-7568-2585"]},"institutions":[{"id":"https://openalex.org/I114131015","display_name":"Stowers Institute for Medical Research","ror":"https://ror.org/04bgfm609","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I114131015"]},{"id":"https://openalex.org/I4210128618","display_name":"University of Kansas Medical Center","ror":"https://ror.org/036c9yv20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210128618"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael P. Washburn","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, 66160, Kansas, USA","Stowers Institute for Medical Research, Kansas City, 64110, Missouri, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, 66160, Kansas, USA","institution_ids":["https://openalex.org/I4210128618"]},{"raw_affiliation_string":"Stowers Institute for Medical Research, Kansas City, 64110, Missouri, USA","institution_ids":["https://openalex.org/I114131015"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070943483","display_name":"Jacek Skowro\u0144ski","orcid":"https://orcid.org/0000-0001-7417-0764","observed_orcids":["https://orcid.org/0000-0001-7417-0764"]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jacek Skowronski","raw_affiliation_strings":["Cold Spring Harbor Laboratory, Cold Spring Harbor, 11724, New York, USA","Department of Molecular Biology and Microbiology, Case School of Medicine, Cleveland, 44106, Ohio, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, Cold Spring Harbor, 11724, New York, USA","institution_ids":["https://openalex.org/I2750212522"]},{"raw_affiliation_string":"Department of Molecular Biology and Microbiology, Case School of Medicine, Cleveland, 44106, Ohio, USA","institution_ids":["https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5070943483"],"corresponding_institution_ids":["https://openalex.org/I2750212522","https://openalex.org/I58956616"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":48.2547,"has_fulltext":false,"cited_by_count":1199,"citation_normalized_percentile":{"value":0.99957301,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"474","issue":"7353","first_page":"658","last_page":"661"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-1","display_name":"HIV-1","score":0.8529999852180481},{"id":"https://openalex.org/keywords/vpx","display_name":"Vpx","score":0.9649999737739563},{"id":"https://openalex.org/keywords/samhd1","display_name":"SAMHD1","score":1.0},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.8360000252723694},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.9940000176429749},{"id":"https://openalex.org/keywords/restriction-factors","display_name":"host restriction factors","score":0.7179999947547913},{"id":"https://openalex.org/keywords/proteasomal-degradation","display_name":"proteasomal degradation","score":0.7990000247955322},{"id":"https://openalex.org/keywords/aicardi-goutieres-syndrome","display_name":"Aicardi-Gouti\u00e8res syndrome","score":0.8980000019073486},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.6489999890327454},{"id":"https://openalex.org/keywords/interferon-response","display_name":"interferon response","score":0.7080000042915344},{"id":"https://openalex.org/keywords/retrovirus-infection","display_name":"retroviral infection","score":0.5849999785423279},{"id":"https://openalex.org/keywords/hiv-2","display_name":"HIV-2","score":0.8130000233650208},{"id":"https://openalex.org/keywords/simian-immunodeficiency-virus","display_name":"simian immunodeficiency virus","score":0.8629999756813049}],"concepts":[{"id":"https://openalex.org/C2776315342","wikidata":"https://www.wikidata.org/wiki/Q21105865","display_name":"SAMHD1","level":5,"score":0.9750052690505981},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.7753583788871765},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.709749698638916},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.6103031039237976},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6019482612609863},{"id":"https://openalex.org/C134459356","wikidata":"https://www.wikidata.org/wiki/Q4274835","display_name":"Ubiquitin ligase","level":4,"score":0.5534749031066895},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5228546261787415},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.48240387439727783},{"id":"https://openalex.org/C25602115","wikidata":"https://www.wikidata.org/wiki/Q407111","display_name":"Ubiquitin","level":3,"score":0.4722009599208832},{"id":"https://openalex.org/C2777995582","wikidata":"https://www.wikidata.org/wiki/Q1890246","display_name":"Simian immunodeficiency virus","level":3,"score":0.45616063475608826},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.4425183832645416},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3253463804721832},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.30828216671943665},{"id":"https://openalex.org/C156719811","wikidata":"https://www.wikidata.org/wiki/Q28774","display_name":"Reverse transcriptase","level":4,"score":0.24934369325637817},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.24703449010849},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11561498045921326},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0924597680568695}],"mesh":[{"descriptor_ui":"D000076106","descriptor_name":"SAM Domain and HD Domain-Containing Protein 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D009687","descriptor_name":"Nuclear Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D017346","descriptor_name":"Protein Serine-Threonine Kinases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020559","descriptor_name":"Monomeric GTP-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D044767","descriptor_name":"Ubiquitin-Protein Ligases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D046988","descriptor_name":"Proteasome Endopeptidase Complex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D054334","descriptor_name":"Viral Regulatory and Accessory Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D057809","descriptor_name":"HEK293 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1038/nature10195","doi":"https://doi.org/10.1038/nature10195","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nature10195","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},{"id":"pmid:21720370","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21720370","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2251764","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3179858","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3179858","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3179858","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nature","raw_type":"Text"},{"id":"pmh:oai:repository.cshl.edu:15649","doi":null,"is_oa":false,"landing_page_url":"https://repository.cshl.edu/id/eprint/15649/","pdf_url":null,"source":{"id":"https://openalex.org/S4306402288","display_name":"Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Paper"},{"id":"pmh:oai:RePEc:nat:nature:v:474:y:2011:i:7353:d:10.1038_nature10195","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/nature10195","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2251764","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3179858","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8199999928474426}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6793128001","display_name":"Regulators and mediators of TRIM5 function","funder_award_id":"R21AI084694","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8086559934","display_name":"MOLECULAR BIOLOGY OF LENTIVIRAL VPR AND VPX PROTEINS","funder_award_id":"R01AI077459","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1517131856","https://openalex.org/W1577222354","https://openalex.org/W1969888906","https://openalex.org/W1972585314","https://openalex.org/W1982410222","https://openalex.org/W1985585046","https://openalex.org/W2009320893","https://openalex.org/W2009761723","https://openalex.org/W2012285063","https://openalex.org/W2017760549","https://openalex.org/W2019039109","https://openalex.org/W2026218505","https://openalex.org/W2031875199","https://openalex.org/W2050598058","https://openalex.org/W2060371587","https://openalex.org/W2068349374","https://openalex.org/W2078138443","https://openalex.org/W2100892474","https://openalex.org/W2111969980","https://openalex.org/W2117785982","https://openalex.org/W2126947051","https://openalex.org/W2132333091","https://openalex.org/W2136400402","https://openalex.org/W2138933731","https://openalex.org/W2155838330","https://openalex.org/W2164722422","https://openalex.org/W2167317609","https://openalex.org/W2318127668","https://openalex.org/W2330865564","https://openalex.org/W2413189460"],"related_works":["https://openalex.org/W2069554621","https://openalex.org/W2075864586","https://openalex.org/W2136306649","https://openalex.org/W2003282007","https://openalex.org/W2045628835","https://openalex.org/W7097815331","https://openalex.org/W2085318117","https://openalex.org/W6941489028","https://openalex.org/W3116599082","https://openalex.org/W2101381491"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":30},{"year":2025,"cited_by_count":51},{"year":2024,"cited_by_count":54},{"year":2023,"cited_by_count":47},{"year":2022,"cited_by_count":61},{"year":2021,"cited_by_count":58},{"year":2020,"cited_by_count":66},{"year":2019,"cited_by_count":82},{"year":2018,"cited_by_count":88},{"year":2017,"cited_by_count":87},{"year":2016,"cited_by_count":91},{"year":2015,"cited_by_count":101},{"year":2014,"cited_by_count":125},{"year":2013,"cited_by_count":125},{"year":2012,"cited_by_count":109}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}