{"id":"https://openalex.org/W1964458683","doi":"https://doi.org/10.1186/1471-2172-14-47","title":"Lupus-like oral mucosal lesions in mercury-induced autoimmune response in Brown Norway rats","display_name":"Lupus-like oral mucosal lesions in mercury-induced autoimmune response in Brown Norway rats","publication_year":2013,"publication_date":"2013-10-03","ids":{"openalex":"https://openalex.org/W1964458683","doi":"https://doi.org/10.1186/1471-2172-14-47","mag":"1964458683","pmid":"https://pubmed.ncbi.nlm.nih.gov/24089704","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3852543"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2172-14-47","doi":"https://doi.org/10.1186/1471-2172-14-47","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2172-14-47","pdf_url":"https://bmcimmunol.biomedcentral.com/counter/pdf/10.1186/1471-2172-14-47","source":{"id":"https://openalex.org/S127311448","display_name":"BMC Immunology","issn_l":"1471-2172","issn":["1471-2172"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcimmunol.biomedcentral.com/counter/pdf/10.1186/1471-2172-14-47","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016023343","display_name":"Kei Seno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I81810807","display_name":"Fukuoka Dental College","ror":"https://ror.org/04zkc6t29","country_code":"JP","type":"education","lineage":["https://openalex.org/I81810807"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kei Seno","raw_affiliation_strings":["Department of Morphological Biology, Division of Pathology, Fukuoka Dental College, 2-15-1 Tamura, Fukuoka, Japan. johno@college.fdcnet.ac.jp","Department of General Dentistry, Division of General Dentistry, Fukuoka Dental College, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Morphological Biology, Division of Pathology, Fukuoka Dental College, 2-15-1 Tamura, Fukuoka, Japan. johno@college.fdcnet.ac.jp","institution_ids":["https://openalex.org/I81810807"]},{"raw_affiliation_string":"Department of General Dentistry, Division of General Dentistry, Fukuoka Dental College, Fukuoka, Japan","institution_ids":["https://openalex.org/I81810807"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023883587","display_name":"Jun Ohno","orcid":"https://orcid.org/0000-0002-7790-1603","observed_orcids":["https://orcid.org/0000-0002-7790-1603"]},"institutions":[{"id":"https://openalex.org/I81810807","display_name":"Fukuoka Dental College","ror":"https://ror.org/04zkc6t29","country_code":"JP","type":"education","lineage":["https://openalex.org/I81810807"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Jun Ohno","raw_affiliation_strings":["Department of Morphological Biology, Division of Pathology, Fukuoka Dental College, 2-15-1, Tamura, Fukuoka, Japan","Department of Morphological Biology, Division of Pathology, Fukuoka Dental College, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Morphological Biology, Division of Pathology, Fukuoka Dental College, 2-15-1, Tamura, Fukuoka, Japan","institution_ids":["https://openalex.org/I81810807"]},{"raw_affiliation_string":"Department of Morphological Biology, Division of Pathology, Fukuoka Dental College, Fukuoka, Japan","institution_ids":["https://openalex.org/I81810807"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nobutaka Ota","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I81810807","display_name":"Fukuoka Dental College","ror":"https://ror.org/04zkc6t29","country_code":"JP","type":"education","lineage":["https://openalex.org/I81810807"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobutaka Ota","raw_affiliation_strings":["Department of Oral and Maxillofacial Surgery, Division of Oral Oncology, Fukuoka Dental College, 2-15-1, Tamura, Fukuoka, Japan","Department of Oral and Maxillofacial Surgery, Division of Oral Oncology, Fukuoka Dental College, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Surgery, Division of Oral Oncology, Fukuoka Dental College, 2-15-1, Tamura, Fukuoka, Japan","institution_ids":["https://openalex.org/I81810807"]},{"raw_affiliation_string":"Department of Oral and Maxillofacial Surgery, Division of Oral Oncology, Fukuoka Dental College, Fukuoka, Japan","institution_ids":["https://openalex.org/I81810807"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069393572","display_name":"Takao Hirofuji","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I81810807","display_name":"Fukuoka Dental College","ror":"https://ror.org/04zkc6t29","country_code":"JP","type":"education","lineage":["https://openalex.org/I81810807"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takao Hirofuji","raw_affiliation_strings":["Department of General Dentistry, Division of General Dentistry, Fukuoka Dental College, 2-15-1, Tamura, Fukuoka, Japan","Department of General Dentistry, Division of General Dentistry, Fukuoka Dental College, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Dentistry, Division of General Dentistry, Fukuoka Dental College, 2-15-1, Tamura, Fukuoka, Japan","institution_ids":["https://openalex.org/I81810807"]},{"raw_affiliation_string":"Department of General Dentistry, Division of General Dentistry, Fukuoka Dental College, Fukuoka, Japan","institution_ids":["https://openalex.org/I81810807"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111367002","display_name":"Kunihisa Taniguchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I81810807","display_name":"Fukuoka Dental College","ror":"https://ror.org/04zkc6t29","country_code":"JP","type":"education","lineage":["https://openalex.org/I81810807"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kunihisa Taniguchi","raw_affiliation_strings":["Department of Morphological Biology, Division of Pathology, Fukuoka Dental College, 2-15-1, Tamura, Fukuoka, Japan","Department of Morphological Biology, Division of Pathology, Fukuoka Dental College, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Morphological Biology, Division of Pathology, Fukuoka Dental College, 2-15-1, Tamura, Fukuoka, Japan","institution_ids":["https://openalex.org/I81810807"]},{"raw_affiliation_string":"Department of Morphological Biology, Division of Pathology, Fukuoka Dental College, Fukuoka, Japan","institution_ids":["https://openalex.org/I81810807"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5023883587"],"corresponding_institution_ids":["https://openalex.org/I81810807"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":{"value":3090,"currency":"USD","value_usd":3090},"fwci":0.6475,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.68318881,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"14","issue":"1","first_page":"47","last_page":"47"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11452","display_name":"Oral Health Pathology and Treatment","score":0.025299999862909317,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mercury-induced-autoimmunity","display_name":"mercury-induced autoimmunity","score":0.9449999928474426},{"id":"https://openalex.org/keywords/brown-norway-rats","display_name":"Brown Norway rats","score":0.7549999952316284},{"id":"https://openalex.org/keywords/oral-mucosa","display_name":"oral mucosa","score":0.7820000052452087},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.777999997138977},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.8949999809265137},{"id":"https://openalex.org/keywords/t-cell-infiltration","display_name":"T cell infiltration","score":0.8519999980926514},{"id":"https://openalex.org/keywords/il-4","display_name":"IL-4","score":0.953000009059906},{"id":"https://openalex.org/keywords/th2-response","display_name":"Th2 immune response","score":0.9089999794960022},{"id":"https://openalex.org/keywords/immune-complex-deposits","display_name":"immune complex deposits","score":0.8379999995231628},{"id":"https://openalex.org/keywords/lupus-band-test","display_name":"lupus band test","score":0.8500000238418579}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6182176470756531},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5647073984146118},{"id":"https://openalex.org/C153400128","wikidata":"https://www.wikidata.org/wiki/Q3150731","display_name":"Infiltration (HVAC)","level":2,"score":0.5541856288909912},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5434697866439819},{"id":"https://openalex.org/C2780130043","wikidata":"https://www.wikidata.org/wiki/Q192360","display_name":"Autoimmunity","level":3,"score":0.518550455570221},{"id":"https://openalex.org/C2779409057","wikidata":"https://www.wikidata.org/wiki/Q1776131","display_name":"Oral mucosa","level":2,"score":0.4966619610786438},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.48858746886253357},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42218005657196045},{"id":"https://openalex.org/C2776912625","wikidata":"https://www.wikidata.org/wiki/Q1485","display_name":"Systemic lupus erythematosus","level":3,"score":0.4143151044845581},{"id":"https://openalex.org/C2780648854","wikidata":"https://www.wikidata.org/wiki/Q2745824","display_name":"Immunopathology","level":2,"score":0.4140453040599823},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.40974128246307373},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.20371711254119873},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007279","descriptor_name":"Injections, Subcutaneous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008628","descriptor_name":"Mercury","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009061","descriptor_name":"Mouth Mucosa","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009061","descriptor_name":"Mouth Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009061","descriptor_name":"Mouth Mucosa","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011914","descriptor_name":"Rats, Inbred BN","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014059","descriptor_name":"Tongue","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014059","descriptor_name":"Tongue","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014059","descriptor_name":"Tongue","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015551","descriptor_name":"Autoimmunity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015551","descriptor_name":"Autoimmunity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015847","descriptor_name":"Interleukin-4","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015847","descriptor_name":"Interleukin-4","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018956","descriptor_name":"CD5 Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018956","descriptor_name":"CD5 Antigens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2172-14-47","doi":"https://doi.org/10.1186/1471-2172-14-47","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2172-14-47","pdf_url":"https://bmcimmunol.biomedcentral.com/counter/pdf/10.1186/1471-2172-14-47","source":{"id":"https://openalex.org/S127311448","display_name":"BMC Immunology","issn_l":"1471-2172","issn":["1471-2172"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Immunology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2838562","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3852543","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:24089704","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24089704","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC immunology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3852543","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3852543/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Immunol","raw_type":"Text"},{"id":"pmh:oai:irdb.nii.ac.jp:01414:0002617757","doi":null,"is_oa":true,"landing_page_url":"https://fdc.repo.nii.ac.jp/records/50","pdf_url":"https://fdc.repo.nii.ac.jp/record/50/files/%E7%94%B2%E7%AC%AC273%E5%8F%B7_%E8%AB%96%E6%96%87(%E7%80%A8%E9%87%8E).pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoral thesis"}],"best_oa_location":{"id":"doi:10.1186/1471-2172-14-47","doi":"https://doi.org/10.1186/1471-2172-14-47","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2172-14-47","pdf_url":"https://bmcimmunol.biomedcentral.com/counter/pdf/10.1186/1471-2172-14-47","source":{"id":"https://openalex.org/S127311448","display_name":"BMC Immunology","issn_l":"1471-2172","issn":["1471-2172"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4133338442","display_name":"Autophagy-mediated cell death in cancer initiating cells of oral squamous cell carcinoma","funder_award_id":"25670802","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6452169172","display_name":"Effect of Lactobacillus species on the general health and periodontal disease of the elderly requiring care","funder_award_id":"23593078","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7203423678","display_name":"Pathogenesis of T cell-mediated immune disorders in oral mucosa","funder_award_id":"24390422","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7701351841","display_name":"\u53e3\u8154\u764c\u30ea\u30f3\u30d1\u7bc0\u8ee2\u79fb\u3067\u306e\u816b\u760d\u7d30\u80de\u30fb\u30ea\u30f3\u30d1\u7ba1\u306e\u76f8\u4e92\u4f5c\u7528\u6a5f\u5e8f\u3068\u305d\u306e\u6291\u5236\u3078\u306e\u30a2\u30d7\u30ed\u30fc\u30c1","funder_award_id":"24592856","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1964458683.pdf","grobid_xml":"https://content.openalex.org/works/W1964458683.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W10420781","https://openalex.org/W1209482520","https://openalex.org/W1459783841","https://openalex.org/W1564328851","https://openalex.org/W1963852643","https://openalex.org/W1965476731","https://openalex.org/W1965719800","https://openalex.org/W1968883463","https://openalex.org/W1972922050","https://openalex.org/W1976531092","https://openalex.org/W1979082964","https://openalex.org/W2001825901","https://openalex.org/W2004100941","https://openalex.org/W2005830693","https://openalex.org/W2010006410","https://openalex.org/W2010127916","https://openalex.org/W2017023636","https://openalex.org/W2022164897","https://openalex.org/W2024108088","https://openalex.org/W2027164905","https://openalex.org/W2029853233","https://openalex.org/W2031501484","https://openalex.org/W2038394756","https://openalex.org/W2045289862","https://openalex.org/W2047877511","https://openalex.org/W2069092857","https://openalex.org/W2076222887","https://openalex.org/W2095048360","https://openalex.org/W2095565628","https://openalex.org/W2120118612","https://openalex.org/W2133281539","https://openalex.org/W2141086538","https://openalex.org/W2168384861","https://openalex.org/W2257004324","https://openalex.org/W2301852713","https://openalex.org/W2409835988"],"related_works":["https://openalex.org/W1968883463","https://openalex.org/W2038394756","https://openalex.org/W2047349061","https://openalex.org/W1974636808","https://openalex.org/W2005830693","https://openalex.org/W590074569","https://openalex.org/W2409835988","https://openalex.org/W7095605912","https://openalex.org/W7098203808","https://openalex.org/W2004984498"],"abstract_inverted_index":{"BACKGROUND:":[0],"Administration":[1],"of":[2,18,51,59,81,86,131,133,141,153,162,169,175,187,193,221,248,252],"mercury":[3,77],"at":[4,78,103],"nontoxic":[5],"doses":[6],"induces":[7],"systemic":[8,61],"autoimmune":[9,241],"disease":[10],"in":[11,40,56,181,198,225,230,245],"Brown":[12,64],"Norway":[13,65],"(BN)":[14],"rats.":[15,43],"The":[16],"pathogenesis":[17,247],"lupus-like":[19,52,250],"oral":[20,32,53,189,227,254],"mucosal":[21,54,118],"lesion":[22],"by":[23,108],"mercury-induced":[24,60,249],"autoimmunity":[25],"is":[26,34],"still":[27],"unclear,":[28],"even":[29],"though":[30],"the":[31,49,129,182,188,226,246,253],"mucosa":[33],"observed":[35,180,224],"to":[36,123,232],"be":[37,209],"commonly":[38],"affected":[39],"mercury-treated":[41],"BN":[42],"In":[44],"this":[45],"study,":[46],"we":[47],"investigated":[48],"immunopathology":[50],"lesions":[55,119,200,251],"a":[57,79],"model":[58],"autoimmunity.":[62],"METHODS:":[63],"male":[66],"rats":[67],"were":[68,101,120],"injected":[69],"subcutaneously":[70],"with":[71],"either":[72],"phosphate-buffered":[73],"saline":[74],"(control)":[75],"or":[76],"dose":[80],"1.0":[82],"mg":[83],"per":[84],"kilogram":[85],"body":[87],"weight":[88],"on":[89,128],"days":[90],"0,":[91],"3,":[92],"5,":[93],"and":[94,98,111,148,157,171,177,217],"7.":[95],"Blood,":[96],"kidney,":[97],"tongue":[99],"samples":[100],"taken":[102],"various":[104],"timepoints":[105],"for":[106,211],"evaluation":[107],"immunohistochemistry,":[109],"RT-PCR,":[110],"lupus":[112],"band":[113],"test":[114],"(LBT).":[115],"RESULTS:":[116],"Oral":[117],"classified":[121],"according":[122],"three":[124],"consecutive":[125],"temporal":[126],"phases":[127],"basis":[130],"infiltration":[132,140,161,168,174],"immunocompetent":[134],"cells":[135,146,165],"as":[136],"follows:":[137],"(phase":[138,150,158,201],"I)":[139],"MHC":[142],"class":[143],"II+":[144],"dendritic":[145],"(DC)":[147],"macrophages;":[149],"II)":[151],"addition":[152,231],"ED1+":[154],"macrophage":[155],"infiltrates;":[156],"III)":[159],"focal":[160],"pan":[163],"T":[164],"following":[166],"increased":[167],"DC":[170,176],"macrophages.":[172],"Dense":[173],"macrophages":[178],"was":[179,196,223],"basement":[183],"membrane":[184],"(BM)":[185],"zone":[186],"epithelium.":[190],"Tissue":[191],"expression":[192],"IL-4":[194,207],"mRNA":[195],"detected":[197],"early":[199],"I),":[202],"suggesting":[203],"that":[204],"locally":[205],"produced":[206],"may":[208],"responsible":[210],"Th2-mediated":[212],"immune":[213,236],"response.":[214],"A":[215],"linear":[216],"continuous":[218],"smooth":[219],"pattern":[220],"fluorescence":[222],"epithelial":[228],"BM":[229],"renal":[233],"glomeruli,":[234],"indicating":[235],"complex":[237],"deposits.":[238],"CONCLUSIONS:":[239],"Local":[240],"responses":[242],"are":[243],"involved":[244],"mucosa.":[255]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}