{"id":"https://openalex.org/W1964352014","doi":"https://doi.org/10.1016/j.jcma.2013.11.008","title":"Preoperative chemoradiotherapy with oxaliplatin and tegafur-uracil in locally advanced rectal cancer: Pathologic complete response rate and preliminary results of overall and disease-free survival in a single institute in Taiwan","display_name":"Preoperative chemoradiotherapy with oxaliplatin and tegafur-uracil in locally advanced rectal cancer: Pathologic complete response rate and preliminary results of overall and disease-free survival in a single institute in Taiwan","publication_year":2014,"publication_date":"2014-01-04","ids":{"openalex":"https://openalex.org/W1964352014","doi":"https://doi.org/10.1016/j.jcma.2013.11.008","mag":"1964352014","pmid":"https://pubmed.ncbi.nlm.nih.gov/24398439"},"language":"en","primary_location":{"id":"doi:10.1016/j.jcma.2013.11.008","doi":"https://doi.org/10.1016/j.jcma.2013.11.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jcma.2013.11.008","pdf_url":null,"source":{"id":"https://openalex.org/S187201833","display_name":"Journal of the Chinese Medical Association","issn_l":"1726-4901","issn":["1726-4901","1728-7731"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Chinese Medical Association","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111970778","display_name":"Jeffrey Y.C. Chao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]},{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jeffrey Yung-Chuan Chao","raw_affiliation_strings":["Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; Institute of Clinical Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; Institute of Clinical Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I4210091773","https://openalex.org/I4387156312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005673231","display_name":"Hwei\u2010Ming Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hwei-Ming Wang","raw_affiliation_strings":["Section of Colon and Rectal Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Colon and Rectal Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I4210091773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069275152","display_name":"Feng\u2010Fan Chiang","orcid":"https://orcid.org/0000-0002-5071-3370","observed_orcids":["https://orcid.org/0000-0002-5071-3370"]},"institutions":[{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Feng-Fan Chiang","raw_affiliation_strings":["Section of Colon and Rectal Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Colon and Rectal Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I4210091773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028325045","display_name":"Jing-Chin Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]},{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jing-Chin Lin","raw_affiliation_strings":["Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC","Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I4210091773"]},{"raw_affiliation_string":"Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I4210091773","https://openalex.org/I4387156312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102263811","display_name":"Chen-Fa Chang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chen-Fa Chang","raw_affiliation_strings":["Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I4210091773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010783501","display_name":"Jia\u2010Fu Lin","orcid":"https://orcid.org/0000-0001-5387-1967","observed_orcids":["https://orcid.org/0000-0001-5387-1967"]},"institutions":[{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]},{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jia-Fu Lin","raw_affiliation_strings":["Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC","Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I4210091773"]},{"raw_affiliation_string":"Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I4210091773","https://openalex.org/I4387156312"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023062132","display_name":"Hui\u2010Ling Yeh","orcid":"https://orcid.org/0000-0003-1810-7079","observed_orcids":["https://orcid.org/0000-0003-1810-7079","https://orcid.org/0000-0002-2530-9341"]},"institutions":[{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Hui-Ling Yeh","raw_affiliation_strings":["Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC. Electronic address: hlyeh@vghtc.gov.tw","Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC. Electronic address: hlyeh@vghtc.gov.tw","institution_ids":["https://openalex.org/I4210091773"]},{"raw_affiliation_string":"Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I4210091773"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5023062132"],"corresponding_institution_ids":["https://openalex.org/I4210091773"],"apc_list":null,"apc_paid":null,"fwci":1.1467,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.77456304,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"77","issue":"3","first_page":"128","last_page":"132"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13110","display_name":"Colorectal and Anal Carcinomas","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/locally-advanced-rectal-cancer","display_name":"locally advanced rectal cancer","score":0.925000011920929},{"id":"https://openalex.org/keywords/neoadjuvant-chemoradiotherapy","display_name":"neoadjuvant chemoradiotherapy","score":0.9279999732971191},{"id":"https://openalex.org/keywords/oxaliplatin","display_name":"oxaliplatin","score":0.9710000157356262},{"id":"https://openalex.org/keywords/tegafur-uracil","display_name":"tegafur-uracil","score":1.0},{"id":"https://openalex.org/keywords/pathological-complete-response","display_name":"pathological complete response","score":0.9290000200271606},{"id":"https://openalex.org/keywords/neoadjuvant-therapy","display_name":"neoadjuvant therapy","score":0.8519999980926514},{"id":"https://openalex.org/keywords/diarrhea-toxicity","display_name":"diarrhea toxicity","score":0.7170000076293945},{"id":"https://openalex.org/keywords/local-control","display_name":"local control","score":0.6320000290870667},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.9819999933242798},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9620000123977661},{"id":"https://openalex.org/keywords/asian-patients","display_name":"Asian patients","score":0.5630000233650208}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9734468460083008},{"id":"https://openalex.org/C2780962732","wikidata":"https://www.wikidata.org/wiki/Q422327","display_name":"Oxaliplatin","level":4,"score":0.737725019454956},{"id":"https://openalex.org/C2777299880","wikidata":"https://www.wikidata.org/wiki/Q413370","display_name":"Tegafur","level":3,"score":0.7242934107780457},{"id":"https://openalex.org/C2778424827","wikidata":"https://www.wikidata.org/wiki/Q5090613","display_name":"Chemoradiotherapy","level":3,"score":0.6846662759780884},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.656347930431366},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6552530527114868},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5640994310379028},{"id":"https://openalex.org/C3019096185","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Complete response","level":3,"score":0.5129560828208923},{"id":"https://openalex.org/C3019894029","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Overall survival","level":2,"score":0.449106901884079},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4411030411720276},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.30886369943618774},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.22290638089179993}],"mesh":[{"descriptor_ui":"D000077150","descriptor_name":"Oxaliplatin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005641","descriptor_name":"Tegafur","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009944","descriptor_name":"Organoplatinum Compounds","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D013624","descriptor_name":"Taiwan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014498","descriptor_name":"Uracil","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020360","descriptor_name":"Neoadjuvant Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057234","descriptor_name":"Preoperative Period","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059248","descriptor_name":"Chemoradiotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jcma.2013.11.008","doi":"https://doi.org/10.1016/j.jcma.2013.11.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jcma.2013.11.008","pdf_url":null,"source":{"id":"https://openalex.org/S187201833","display_name":"Journal of the Chinese Medical Association","issn_l":"1726-4901","issn":["1726-4901","1728-7731"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Chinese Medical Association","raw_type":"journal-article"},{"id":"pmid:24398439","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24398439","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Chinese Medical Association : JCMA","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W427958308","https://openalex.org/W2007296899","https://openalex.org/W2015769498","https://openalex.org/W2016554744","https://openalex.org/W2023623711","https://openalex.org/W2027441417","https://openalex.org/W2043108956","https://openalex.org/W2097158913","https://openalex.org/W2113353705","https://openalex.org/W2121368761","https://openalex.org/W2123377696","https://openalex.org/W2123712900","https://openalex.org/W2124695217","https://openalex.org/W2125452425","https://openalex.org/W2128403792","https://openalex.org/W2156741131","https://openalex.org/W2159700133","https://openalex.org/W2256339062"],"related_works":["https://openalex.org/W2388319304","https://openalex.org/W2619766448","https://openalex.org/W4408956624","https://openalex.org/W1967509913","https://openalex.org/W1531388876","https://openalex.org/W2123712900","https://openalex.org/W1911303594","https://openalex.org/W2386618248","https://openalex.org/W2520774285","https://openalex.org/W2044427013"],"abstract_inverted_index":{"BACKGROUND:":[0],"We":[1],"conducted":[2],"a":[3,172],"Phase":[4],"II":[5],"study":[6,185],"of":[7,32,75,83,130,175,219],"biweekly":[8],"oxaliplatin":[9,255],"plus":[10],"oral":[11],"tegafur-uracil":[12,109,257],"in":[13,25,36,55,71,80,223,265],"the":[14,30,72,117,131,140,156,184,195,211],"preoperative":[15,132,176],"chemoradiotherapy":[16,253],"(CRT)":[17],"for":[18,90,99],"locally":[19,269],"advanced":[20,270],"resectable":[21],"mid-to-lower":[22,271],"rectal":[23,65,272],"cancer":[24,66],"our":[26,266],"hospital,":[27],"to":[28,52,138,154,166],"evaluate":[29],"feasibility":[31],"this":[33,147],"drug":[34],"combination":[35],"tumor":[37],"pathologic":[38,141],"response,":[39],"acute":[40],"toxicity,":[41],"local":[42,160,181],"control,":[43,161],"disease-free":[44],"survival":[45,48],"(DFS),":[46],"overall":[47],"(OS),":[49],"and":[50,108,164,194,243,248,256,260],"time":[51,165],"distant":[53],"metastasis":[54],"an":[56,262],"Asian":[57],"cohort.":[58],"METHODS:":[59],"Twenty":[60],"patients":[61,170,267],"with":[62,254,268],"histopathologically":[63],"confirmed":[64],"(Stage":[67],"II-III)":[68],"were":[69,227,246],"enrolled":[70],"study.":[73],"Radiotherapy":[74],"50":[76],"Gy":[77],"was":[78,96,112,124,137,153,179,191,200,206,215,258],"delivered":[79],"25":[81],"fractions":[82],"2":[84,106,222],"Gy,":[85],"one":[86],"fraction/day,":[87],"five":[88],"fractions/week,":[89],"5":[91],"weeks.":[92],"Oxaliplatin":[93],"55":[94],"mg/m(2)":[95,111],"administered":[97],"intravenously":[98],"60":[100],"minutes":[101],"on":[102],"Day":[103],"1":[104],"every":[105],"weeks,":[107],"350":[110],"given":[113],"orally":[114],"everyday":[115],"during":[116,183],"whole":[118],"radiotherapy":[119],"course,":[120],"including":[121],"holidays.":[122],"Surgery":[123],"scheduled":[125],"6":[126],"weeks":[127],"after":[128,146],"completion":[129],"chemoradiotherapy.":[133,149,177],"The":[134,150,187,203,240],"primary":[135],"endpoint":[136,152],"determine":[139,155],"complete":[142,173,188],"response":[143],"(pCR)":[144],"rate":[145,190,199,205],"neoadjuvant":[148],"secondary":[151],"treatment-related":[157,238],"toxicity":[158,214],"profile,":[159],"DFS,":[162],"OS,":[163],"metastasis.":[167],"RESULTS:":[168],"All":[169],"underwent":[171],"course":[174],"There":[178,226],"no":[180,228],"recurrence":[182],"period.":[186],"resection":[189,197],"20/20":[192],"(100%)":[193],"close":[196],"margin":[198],"3/20":[201],"(15%).":[202],"pCR":[204,264],"8/20":[207],"(40%).":[208],"During":[209],"chemoradiotherapy,":[210],"most":[212],"frequent":[213],"diarrhea":[216],"9/20":[217],"(45%":[218],"patients,":[220],"grade":[221,229],"3/20,":[224],"15%).":[225],"3":[230],"or":[231,234,237],"higher":[232],"hematologic":[233],"non-hematologic":[235],"events":[236],"deaths.":[239],"3-year":[241],"OS":[242],"DFS":[244],"rates":[245],"94.1%":[247],"78.6%,":[249],"respectively.":[250],"CONCLUSION:":[251],"Preoperative":[252],"well-tolerated":[259],"achieved":[261],"excellent":[263],"cancer.":[273]},"counts_by_year":[{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}