{"id":"https://openalex.org/W1963955005","doi":"https://doi.org/10.1006/niox.2000.0279","title":"Blood Pressure Changes after Intravenous Administration of Cell-Free Hemoglobin A and Hemoglobin H in the Rat","display_name":"Blood Pressure Changes after Intravenous Administration of Cell-Free Hemoglobin A and Hemoglobin H in the Rat","publication_year":2000,"publication_date":"2000-04-01","ids":{"openalex":"https://openalex.org/W1963955005","doi":"https://doi.org/10.1006/niox.2000.0279","mag":"1963955005","pmid":"https://pubmed.ncbi.nlm.nih.gov/10835294"},"language":"en","primary_location":{"id":"doi:10.1006/niox.2000.0279","doi":"https://doi.org/10.1006/niox.2000.0279","is_oa":false,"landing_page_url":"https://doi.org/10.1006/niox.2000.0279","pdf_url":null,"source":{"id":"https://openalex.org/S152998702","display_name":"Nitric Oxide","issn_l":"1089-8603","issn":["1089-8603","1089-8611"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nitric Oxide","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102466784","display_name":"Poluru L. Reddy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Poluru L. Reddy","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Department of Medicine, Evanston Northwestern Health Care, 2650 Ridge Avenue, Evanston, Illinois, 60201, USA. plreddy@AOL.com","Department of Pathology and Laboratory Medicine, Evanston Northwestern Health Care, 2650 Ridge Avenue, Evanston, Illinois, 60201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Department of Medicine, Evanston Northwestern Health Care, 2650 Ridge Avenue, Evanston, Illinois, 60201, USA. plreddy@AOL.com","institution_ids":[]},{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Evanston Northwestern Health Care, 2650 Ridge Avenue, Evanston, Illinois, 60201","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113513108","display_name":"Lemuel J. Bowie","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lemuel J. Bowie","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Evanston Northwestern Health Care, 2650 Ridge Avenue, Evanston, Illinois, 60201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Evanston Northwestern Health Care, 2650 Ridge Avenue, Evanston, Illinois, 60201","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058946620","display_name":"Hongsi Jiang","orcid":"https://orcid.org/0000-0001-6075-1015","observed_orcids":["https://orcid.org/0000-0001-6075-1015"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hongsi Jiang","raw_affiliation_strings":["Department of Medicine, Evanston Northwestern Health Care, 2650 Ridge Avenue, Evanston, Illinois, 60201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Evanston Northwestern Health Care, 2650 Ridge Avenue, Evanston, Illinois, 60201","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5102466784"],"corresponding_institution_ids":[],"apc_list":{"value":3400,"currency":"USD","value_usd":3400},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.07580645,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"4","issue":"2","first_page":"139","last_page":"146"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.9071999788284302,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.9071999788284302,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.06279999762773514,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.0142000000923872,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hemoglobin-h","display_name":"hemoglobin H","score":0.9610000252723694},{"id":"https://openalex.org/keywords/hemoglobin-a","display_name":"hemoglobin A","score":0.9900000095367432},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.7979999780654907},{"id":"https://openalex.org/keywords/alpha-thalassemia","display_name":"alpha-thalassemia","score":0.9309999942779541},{"id":"https://openalex.org/keywords/nitric-oxide-binding","display_name":"nitric oxide binding","score":0.8009999990463257},{"id":"https://openalex.org/keywords/sulfhydryl-groups","display_name":"sulfhydryl groups","score":0.9129999876022339},{"id":"https://openalex.org/keywords/hypertension-risk","display_name":"hypertension risk","score":0.6919999718666077},{"id":"https://openalex.org/keywords/dose-dependent-effects","display_name":"dose-dependent effects","score":0.5329999923706055},{"id":"https://openalex.org/keywords/chronic-drug-administration","display_name":"chronic drug administration","score":0.6309999823570251}],"concepts":[{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.8324134349822998},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7176345586776733},{"id":"https://openalex.org/C2778886173","wikidata":"https://www.wikidata.org/wiki/Q53832","display_name":"Tetramer","level":3,"score":0.6128331422805786},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5316327810287476},{"id":"https://openalex.org/C2776217839","wikidata":"https://www.wikidata.org/wiki/Q189621","display_name":"Heme","level":3,"score":0.4860985279083252},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47228461503982544},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.45021799206733704},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.4369535446166992},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36932066082954407},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3587654232978821},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20403817296028137},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.059711962938308716}],"mesh":[{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006441","descriptor_name":"Hemoglobin A","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006441","descriptor_name":"Hemoglobin A","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006447","descriptor_name":"Hemoglobin H","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006447","descriptor_name":"Hemoglobin H","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007262","descriptor_name":"Infusions, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1006/niox.2000.0279","doi":"https://doi.org/10.1006/niox.2000.0279","is_oa":false,"landing_page_url":"https://doi.org/10.1006/niox.2000.0279","pdf_url":null,"source":{"id":"https://openalex.org/S152998702","display_name":"Nitric Oxide","issn_l":"1089-8603","issn":["1089-8603","1089-8611"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nitric Oxide","raw_type":"journal-article"},{"id":"pmid:10835294","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10835294","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nitric oxide : biology and chemistry","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W70647308","https://openalex.org/W81729044","https://openalex.org/W195907529","https://openalex.org/W983745218","https://openalex.org/W1580076592","https://openalex.org/W1961421830","https://openalex.org/W1980834994","https://openalex.org/W1999029603","https://openalex.org/W2005205544","https://openalex.org/W2007278863","https://openalex.org/W2019013081","https://openalex.org/W2024008258","https://openalex.org/W2033240573","https://openalex.org/W2040062233","https://openalex.org/W2056612989","https://openalex.org/W2063503589","https://openalex.org/W2095115132","https://openalex.org/W2097571046","https://openalex.org/W2104323723","https://openalex.org/W2118593308","https://openalex.org/W2121762897","https://openalex.org/W2150946421","https://openalex.org/W2171057675","https://openalex.org/W2188058480","https://openalex.org/W2319078929","https://openalex.org/W2396068131","https://openalex.org/W2413113357","https://openalex.org/W2414117714"],"related_works":["https://openalex.org/W2150946421","https://openalex.org/W2034906784","https://openalex.org/W2061458010","https://openalex.org/W1431036767","https://openalex.org/W2047757955","https://openalex.org/W2898842913","https://openalex.org/W2075968019","https://openalex.org/W2171057675","https://openalex.org/W28999859","https://openalex.org/W2003772043"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}