{"id":"https://openalex.org/W1963740141","doi":"https://doi.org/10.1136/bmj.299.6691.123","title":"Acute cerebral oedema induced by methotrexate: Authors' reply","display_name":"Acute cerebral oedema induced by methotrexate: Authors' reply","publication_year":1989,"publication_date":"1989-07-08","ids":{"openalex":"https://openalex.org/W1963740141","doi":"https://doi.org/10.1136/bmj.299.6691.123","mag":"1963740141","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1837108"},"language":"en","primary_location":{"id":"doi:10.1136/bmj.299.6691.123","doi":"https://doi.org/10.1136/bmj.299.6691.123","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.299.6691.123","pdf_url":"https://www.bmj.com/content/bmj/299/6691/123.4.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},"volume":null,"type":"letter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.bmj.com/content/bmj/299/6691/123.4.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Russell Lane","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Russell Lane","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111860163","display_name":"P. Hughes","orcid":"https://orcid.org/0000-0002-7443-4990","observed_orcids":["https://orcid.org/0000-0002-7443-4990"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P J Hughes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"299","issue":"6691","first_page":"123.4","last_page":"123"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":0.2915000021457672,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":0.2915000021457672,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":0.22179999947547913,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11929","display_name":"Cerebral Venous Sinus Thrombosis","score":0.0632999986410141,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/methotrexate","display_name":"methotrexate","score":0.9589999914169312},{"id":"https://openalex.org/keywords/drug-induced-brain-injury","display_name":"drug-induced brain injury","score":0.5770000219345093},{"id":"https://openalex.org/keywords/intracerebral-hematoma","display_name":"intracerebral hematoma","score":0.9789999723434448},{"id":"https://openalex.org/keywords/hemorrhage","display_name":"hemorrhage","score":0.550000011920929},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.4309999942779541},{"id":"https://openalex.org/keywords/aneurysm","display_name":"aneurysm","score":0.8989999890327454}],"concepts":[{"id":"https://openalex.org/C2781059491","wikidata":"https://www.wikidata.org/wiki/Q422232","display_name":"Methotrexate","level":2,"score":0.5424221158027649},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.49381646513938904},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3521234393119812},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24744272232055664}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1136/bmj.299.6691.123","doi":"https://doi.org/10.1136/bmj.299.6691.123","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.299.6691.123","pdf_url":"https://www.bmj.com/content/bmj/299/6691/123.4.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:433391","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1837108","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1837108","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1837108/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1136/bmj.299.6691.123","doi":"https://doi.org/10.1136/bmj.299.6691.123","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmj.299.6691.123","pdf_url":"https://www.bmj.com/content/bmj/299/6691/123.4.full.pdf","source":{"id":"https://openalex.org/S4393911389","display_name":"BMJ","issn_l":"0007-1447","issn":["0007-1447","0267-0623","1468-5833"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1963740141.pdf","grobid_xml":"https://content.openalex.org/works/W1963740141.grobid-xml"},"referenced_works_count":4,"referenced_works":["https://openalex.org/W1991656994","https://openalex.org/W1995361337","https://openalex.org/W2011108266","https://openalex.org/W2038880185"],"related_works":["https://openalex.org/W2080515006","https://openalex.org/W1977609068","https://openalex.org/W1992703619","https://openalex.org/W2002091940","https://openalex.org/W2019472206","https://openalex.org/W2045668572","https://openalex.org/W2002943549","https://openalex.org/W4389404686","https://openalex.org/W2397453152","https://openalex.org/W2077965986"],"abstract_inverted_index":{"haematoma":[0,13,76],"as":[1],"incidental.There":[2],"was":[3,14],"no":[4],"computed":[5],"tomogram":[6],"before":[7],"treatment,":[8],"the":[9,12,22,29,44,91],"aetiology":[10],"of":[11,19,21,36,55,93],"not":[15,26,42],"discussed,":[16],"and":[17,41,69],"results":[18],"examination":[20],"cerebrospinal":[23],"fluid":[24],"were":[25],"given.In":[27],"addition,":[28],"second":[30],"reference":[31],"is":[32,73],"in":[33,43,88],"supplement":[34],"1":[35],"Cancer":[37],"7reatment":[38],"Reports":[39],"1981":[40],"main":[45],"journal.Rather":[46],"than":[47],"postulate":[48],"a":[49,86],"second,":[50],"previously":[51],"un-":[52],"reported":[53],"cause":[54],"this":[56],"patient's":[57],"neurological":[58],"con-":[59],"dition":[60],"it":[61],"would":[62,96],"be":[63,99],"simpler":[64],"to":[65],"follow":[66],"Occam's":[67],"razor":[68],"explain":[70],"that":[71],"which":[72,89],"obvious.The":[74],"intracerebral":[75],"may":[77],"have":[78],"resulted":[79],"from":[80],"hypertension,":[81],"aneurysm,":[82],"or":[83],"haemorrhage":[84],"into":[85],"deposit,":[87],"case":[90],"administration":[92],"metho-":[94],"trexate":[95],"then":[97],"probably":[98],"incidental.":[100]},"counts_by_year":[],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}