{"id":"https://openalex.org/W1963702983","doi":"https://doi.org/10.1016/s0003-4975(97)00297-x","title":"The Brain Uses Mostly Dissolved Oxygen During Profoundly Hypothermic Cardiopulmonary Bypass","display_name":"The Brain Uses Mostly Dissolved Oxygen During Profoundly Hypothermic Cardiopulmonary Bypass","publication_year":1997,"publication_date":"1997-06-01","ids":{"openalex":"https://openalex.org/W1963702983","doi":"https://doi.org/10.1016/s0003-4975(97)00297-x","mag":"1963702983","pmid":"https://pubmed.ncbi.nlm.nih.gov/9205174"},"language":"en","primary_location":{"id":"doi:10.1016/s0003-4975(97)00297-x","doi":"https://doi.org/10.1016/s0003-4975(97)00297-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0003-4975(97)00297-x","pdf_url":null,"source":{"id":"https://openalex.org/S144860794","display_name":"The Annals of Thoracic Surgery","issn_l":"0003-4975","issn":["0003-4975","1552-6259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of Thoracic Surgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015901694","display_name":"Franklin Dexter","orcid":"https://orcid.org/0000-0001-5897-2484","observed_orcids":["https://orcid.org/0000-0001-5897-2484"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Franklin Dexter","raw_affiliation_strings":["Department of Anesthesia, University of Iowa, Iowa City 52242, USA","Department of Anesthesia, University of Iowa, Iowa City, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesia, University of Iowa, Iowa City 52242, USA","institution_ids":["https://openalex.org/I126307644"]},{"raw_affiliation_string":"Department of Anesthesia, University of Iowa, Iowa City, Iowa, USA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104043099","display_name":"Frank H. Kern","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frank H Kern","raw_affiliation_strings":["Department of Anesthesia, University of Iowa, Iowa City, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesia, University of Iowa, Iowa City, Iowa, USA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042976496","display_name":"Bradley J. Hindman","orcid":"https://orcid.org/0000-0003-2242-7980","observed_orcids":["https://orcid.org/0000-0003-2242-7980"]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bradley J Hindman","raw_affiliation_strings":["Department of Anesthesia, University of Iowa, Iowa City, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesia, University of Iowa, Iowa City, Iowa, USA","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007096882","display_name":"William J. Greeley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William J Greeley","raw_affiliation_strings":["Department of Anesthesia, University of Iowa, Iowa City, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesia, University of Iowa, Iowa City, Iowa, USA","institution_ids":["https://openalex.org/I126307644"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5015901694"],"corresponding_institution_ids":["https://openalex.org/I126307644"],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":1.916,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.84783774,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"63","issue":"6","first_page":"1725","last_page":"1729"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.006800000090152025,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiopulmonary-bypass","display_name":"cardiopulmonary bypass","score":0.925000011920929},{"id":"https://openalex.org/keywords/hypothermic-perfusion","display_name":"hypothermic perfusion","score":0.6510000228881836},{"id":"https://openalex.org/keywords/cerebral-oxygen-delivery","display_name":"cerebral oxygen delivery","score":0.777999997138977},{"id":"https://openalex.org/keywords/cerebral-metabolic-rate-for-oxygen","display_name":"cerebral oxygen consumption","score":0.7850000262260437},{"id":"https://openalex.org/keywords/dissolved-oxygen","display_name":"dissolved oxygen","score":0.9470000267028809},{"id":"https://openalex.org/keywords/hemoglobin-oxygen-affinity","display_name":"hemoglobin oxygen affinity","score":0.8330000042915344},{"id":"https://openalex.org/keywords/hemodilution","display_name":"hemodilution","score":0.9049999713897705},{"id":"https://openalex.org/keywords/arterial-oxygen-partial-pressure","display_name":"arterial oxygen partial pressure","score":0.9739999771118164},{"id":"https://openalex.org/keywords/congenital-heart-disease","display_name":"congenital heart disease","score":0.7910000085830688},{"id":"https://openalex.org/keywords/pediatric-cardiac-surgery","display_name":"pediatric cardiac surgery","score":0.7310000061988831},{"id":"https://openalex.org/keywords/cerebral-venous-oxygen-saturation","display_name":"cerebral venous oxygen saturation","score":0.7860000133514404}],"concepts":[{"id":"https://openalex.org/C2778881276","wikidata":"https://www.wikidata.org/wiki/Q552304","display_name":"Cardiopulmonary bypass","level":2,"score":0.8444147706031799},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.7356462478637695},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6842442154884338},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6588222980499268},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.5939276218414307},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.5299376249313354},{"id":"https://openalex.org/C2777390192","wikidata":"https://www.wikidata.org/wiki/Q1036696","display_name":"Hypothermia","level":2,"score":0.5072066783905029},{"id":"https://openalex.org/C68463220","wikidata":"https://www.wikidata.org/wiki/Q27165","display_name":"Partial pressure","level":3,"score":0.4975772202014923},{"id":"https://openalex.org/C195677412","wikidata":"https://www.wikidata.org/wiki/Q4780928","display_name":"Apparent oxygen utilisation","level":3,"score":0.4460085332393646},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.37378519773483276},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3663601279258728},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.16129904985427856},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002315","descriptor_name":"Cardiopulmonary Bypass","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002550","descriptor_name":"Cerebral Veins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007036","descriptor_name":"Hypothermia, Induced","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0003-4975(97)00297-x","doi":"https://doi.org/10.1016/s0003-4975(97)00297-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0003-4975(97)00297-x","pdf_url":null,"source":{"id":"https://openalex.org/S144860794","display_name":"The Annals of Thoracic Surgery","issn_l":"0003-4975","issn":["0003-4975","1552-6259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of Thoracic Surgery","raw_type":"journal-article"},{"id":"pmid:9205174","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9205174","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of thoracic surgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.5099999904632568,"display_name":"Clean water and sanitation","id":"https://metadata.un.org/sdg/6"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1966293657","https://openalex.org/W1975193198","https://openalex.org/W1979562196","https://openalex.org/W1992246524","https://openalex.org/W2000362729","https://openalex.org/W2046827269","https://openalex.org/W2057303543","https://openalex.org/W2072421091","https://openalex.org/W2155485147","https://openalex.org/W2340455827","https://openalex.org/W2407608200","https://openalex.org/W2410787921"],"related_works":["https://openalex.org/W2127953206","https://openalex.org/W3152188234","https://openalex.org/W2348814749","https://openalex.org/W1982040098","https://openalex.org/W2275101712","https://openalex.org/W1988936086","https://openalex.org/W2381907560","https://openalex.org/W108017464","https://openalex.org/W4360755607","https://openalex.org/W2939468263"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}