{"id":"https://openalex.org/W1963592986","doi":"https://doi.org/10.1002/abio.370110506","title":"Microorganisms for lipids","display_name":"Microorganisms for lipids","publication_year":1991,"publication_date":"1991-01-01","ids":{"openalex":"https://openalex.org/W1963592986","doi":"https://doi.org/10.1002/abio.370110506","mag":"1963592986"},"language":"en","primary_location":{"id":"doi:10.1002/abio.370110506","doi":"https://doi.org/10.1002/abio.370110506","is_oa":false,"landing_page_url":"https://doi.org/10.1002/abio.370110506","pdf_url":null,"source":{"id":"https://openalex.org/S103360871","display_name":"Acta Biotechnologica","issn_l":"0138-4988","issn":["0138-4988","1521-3846"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Biotechnologica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110003806","display_name":"Colin Ratledge","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I191240316","display_name":"University of Hull","ror":"https://ror.org/04nkhwh30","country_code":"GB","type":"education","lineage":["https://openalex.org/I191240316"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"C. Ratledge","raw_affiliation_strings":["Department of Applied Biology, The University of Hull, Hull HU6 7RX, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Biology, The University of Hull, Hull HU6 7RX, UK","institution_ids":["https://openalex.org/I191240316"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5110003806"],"corresponding_institution_ids":["https://openalex.org/I191240316"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":147,"citation_normalized_percentile":{"value":0.04688283,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"11","issue":"5","first_page":"429","last_page":"438"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.8920999765396118,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.8920999765396118,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.062300000339746475,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14150","display_name":"Biochemical and biochemical processes","score":0.020500000566244125,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microbial-lipid-production","display_name":"microbial lipid production","score":0.8199999928474426},{"id":"https://openalex.org/keywords/single-cell-oil","display_name":"single cell oil","score":0.9620000123977661},{"id":"https://openalex.org/keywords/cocoa-butter-substitute","display_name":"cocoa butter substitute","score":0.8510000109672546},{"id":"https://openalex.org/keywords/yeast-mutants","display_name":"yeast mutants","score":0.7829999923706055},{"id":"https://openalex.org/keywords/lactose-carbon-source","display_name":"lactose carbon source","score":0.75},{"id":"https://openalex.org/keywords/whey","display_name":"whey","score":0.8109999895095825},{"id":"https://openalex.org/keywords/polyunsaturated-fatty-acids","display_name":"polyunsaturated fatty acids","score":0.9520000219345093},{"id":"https://openalex.org/keywords/gamma-linolenic-acid","display_name":"gamma-linolenic acid","score":0.9760000109672546},{"id":"https://openalex.org/keywords/molds","display_name":"molds","score":0.7360000014305115},{"id":"https://openalex.org/keywords/fatty-acid-production","display_name":"fatty acid production","score":0.34599998593330383}],"concepts":[{"id":"https://openalex.org/C19038510","wikidata":"https://www.wikidata.org/wiki/Q2005087","display_name":"Polyunsaturated fatty acid","level":3,"score":0.6695047616958618},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.5477811098098755},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.5355560183525085},{"id":"https://openalex.org/C2780556605","wikidata":"https://www.wikidata.org/wiki/Q94787","display_name":"Sunflower oil","level":2,"score":0.4704122841358185},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.45638635754585266},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38141554594039917},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32659733295440674},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.30683690309524536},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17517507076263428}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/abio.370110506","doi":"https://doi.org/10.1002/abio.370110506","is_oa":false,"landing_page_url":"https://doi.org/10.1002/abio.370110506","pdf_url":null,"source":{"id":"https://openalex.org/S103360871","display_name":"Acta Biotechnologica","issn_l":"0138-4988","issn":["0138-4988","1521-3846"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Biotechnologica","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.9208999872207642},{"id":"https://metadata.un.org/sdg/12","display_name":"Responsible consumption and production","score":0.6000000238418579}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W1531959471","https://openalex.org/W2004829408","https://openalex.org/W2019289353","https://openalex.org/W2084616362","https://openalex.org/W2085008162","https://openalex.org/W4237991168"],"related_works":["https://openalex.org/W2091129308","https://openalex.org/W2153060753","https://openalex.org/W7020888859","https://openalex.org/W3207132128","https://openalex.org/W7105695163","https://openalex.org/W2031042062","https://openalex.org/W2513980082","https://openalex.org/W7135787602","https://openalex.org/W6991408937","https://openalex.org/W7162848978"],"abstract_inverted_index":{"Abstract":[0],"Micro\u2010organisms":[1],"have":[2],"often":[3],"been":[4],"considered":[5,160],"for":[6,248],"the":[7,21,36,102,119,153,176,187,218,233],"production":[8,27,104,120,220],"of":[9,25,28,38,60,105,121,130,175,183,221],"oils":[10,62],"and":[11,48,197,216,235,246],"fats":[12],"as":[13,43,53,116,118,168,170],"an":[14],"alternative":[15],"to":[16,33,74,77,95,134,143,162,200,208,241],"agricultural":[17,26,98],"commodities.":[18],"However,":[19],"with":[20],"continuing":[22],"low":[23],"cost":[24],"oil\u2010seeds,":[29],"biotechnology":[30],"has":[31],"little":[32],"offer":[34],"in":[35,194,231],"way":[37],"competition":[39],"against":[40],"such":[41,52],"items":[42],"soybean":[44],"oil,":[45,47],"groundnut":[46],"even":[49,56],"polyunsaturated":[50,123,209],"oil":[51,55],"sunflower":[54],"though":[57],"good":[58],"facsimiles":[59],"these":[61,85,202],"could":[63],"be":[64,87,163],"produced.":[65],"It":[66],"is":[67,113,141,158,204,226,244],"now":[68,159,227],"clear":[69],"that":[70],"if":[71],"we":[72],"are":[73,92,254],"use":[75],"microorganisms":[76],"produce":[78],"lipids,":[79],"i.e.":[80],"Single":[81],"Cell":[82],"Oil,":[83],"then":[84],"must":[86],"highly":[88,122],"specific":[89],"ones":[90],"which":[91,152,178],"currently":[93],"expensive":[94],"obtain":[96],"from":[97,166],"sources.":[99],"In":[100],"particular,":[101],"possible":[103],"a":[106,136,147,172],"cocoa\u2010butter":[107,137],"substitute":[108],"using":[109,127],"mutated":[110],"yeast":[111,154,177],"cells":[112],"reviewed":[114],"here":[115],"well":[117,169],"fatty":[124,210],"acids":[125],"(PUFAs)":[126],"various":[128,213],"species":[129],"mould.":[131],"With":[132,206],"regard":[133,207],"producing":[135],"equivalent":[138],"fat,":[139],"it":[140],"necessary":[142],"identify":[144],"not":[145],"only":[146],"cheap":[148],"carbon":[149],"source":[150],"on":[151],"may":[155],"grow":[156],"(this":[157],"likely":[161],"lactose":[164],"arising":[165],"whey)":[167],"deriving":[171],"mutant":[173],"strain":[174],"will":[179],"accumulate":[180],"large":[181],"amounts":[182],"stearic":[184],"acid":[185,211],"within":[186],"oil.":[188],"The":[189,195,237],"recent":[190],"work":[191,239],"carried":[192],"out":[193],"Netherlands":[196],"New":[198],"Zealand":[199],"achieve":[201],"goals":[203],"described.":[205],"production,":[212],"prospects":[214],"exist":[215],"indeed,":[217],"commercial":[219],"one":[222],"acid,":[223,225],"gamma\u2010linolenic":[224],"being":[228,251],"produced":[229,252],"commercially":[230],"both":[232],"U.K.":[234],"Japan.":[236],"background":[238],"leading":[240],"this":[242],"product":[243],"described":[245],"opportunities":[247],"other":[249],"PUFAs":[250],"biotechnologically":[253],"discussed.":[255]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}