{"id":"https://openalex.org/W1963554986","doi":"https://doi.org/10.1016/s0022-3468(97)90307-9","title":"The incidence of renal anomalies at full term in fetal rats is synergistically increased by estradiol (but not testosterone) supplementation on day 18 of alcoholic gestation","display_name":"The incidence of renal anomalies at full term in fetal rats is synergistically increased by estradiol (but not testosterone) supplementation on day 18 of alcoholic gestation","publication_year":1997,"publication_date":"1997-09-01","ids":{"openalex":"https://openalex.org/W1963554986","doi":"https://doi.org/10.1016/s0022-3468(97)90307-9","mag":"1963554986","pmid":"https://pubmed.ncbi.nlm.nih.gov/9314248"},"language":"en","primary_location":{"id":"doi:10.1016/s0022-3468(97)90307-9","doi":"https://doi.org/10.1016/s0022-3468(97)90307-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0022-3468(97)90307-9","pdf_url":null,"source":{"id":"https://openalex.org/S39924113","display_name":"Journal of Pediatric Surgery","issn_l":"0022-3468","issn":["0022-3468","1531-5037"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111702131","display_name":"Christopher J. Calvano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405260259","display_name":"Albany Medical College","ror":"https://ror.org/03g66yt05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405259726","https://openalex.org/I4405260259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher J Calvano","raw_affiliation_strings":["Department of Pharmacology, Albany Medical College, NY 12208, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Albany Medical College, NY 12208, USA","institution_ids":["https://openalex.org/I4405260259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014560751","display_name":"R. LeFevre","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405260259","display_name":"Albany Medical College","ror":"https://ror.org/03g66yt05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405259726","https://openalex.org/I4405260259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rene LeFevre","raw_affiliation_strings":["Division of Urology, Albany Medical College, Albany, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Urology, Albany Medical College, Albany, NY, USA","institution_ids":["https://openalex.org/I4405260259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111830275","display_name":"Russell F. Mankes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405260259","display_name":"Albany Medical College","ror":"https://ror.org/03g66yt05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405259726","https://openalex.org/I4405260259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Russell F Mankes","raw_affiliation_strings":["Division of Urology, Albany Medical College, Albany, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Urology, Albany Medical College, Albany, NY, USA","institution_ids":["https://openalex.org/I4405260259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014487667","display_name":"Pramod P. Reddy","orcid":"https://orcid.org/0000-0002-2554-9054","observed_orcids":["https://orcid.org/0000-0002-2554-9054"]},"institutions":[{"id":"https://openalex.org/I4405260259","display_name":"Albany Medical College","ror":"https://ror.org/03g66yt05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405259726","https://openalex.org/I4405260259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pramod P Reddy","raw_affiliation_strings":["Division of Urology, Albany Medical College, Albany, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Urology, Albany Medical College, Albany, NY, USA","institution_ids":["https://openalex.org/I4405260259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112761357","display_name":"Michael E. Moran","orcid":"https://orcid.org/0000-0002-3882-4414","observed_orcids":["https://orcid.org/0000-0002-3882-4414"]},"institutions":[{"id":"https://openalex.org/I4405260259","display_name":"Albany Medical College","ror":"https://ror.org/03g66yt05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405259726","https://openalex.org/I4405260259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael E Moran","raw_affiliation_strings":["Division of Urology, Albany Medical College, Albany, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Urology, Albany Medical College, Albany, NY, USA","institution_ids":["https://openalex.org/I4405260259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090553721","display_name":"Richard M. Hoar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405260259","display_name":"Albany Medical College","ror":"https://ror.org/03g66yt05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405259726","https://openalex.org/I4405260259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard M Hoar","raw_affiliation_strings":["Division of Urology, Albany Medical College, Albany, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Urology, Albany Medical College, Albany, NY, USA","institution_ids":["https://openalex.org/I4405260259"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111874369","display_name":"James Mandell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405260259","display_name":"Albany Medical College","ror":"https://ror.org/03g66yt05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405259726","https://openalex.org/I4405260259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Mandell","raw_affiliation_strings":["Division of Urology, Albany Medical College, Albany, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Urology, Albany Medical College, Albany, NY, USA","institution_ids":["https://openalex.org/I4405260259"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4405260259"],"apc_list":{"value":4430,"currency":"USD","value_usd":4430},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"32","issue":"9","first_page":"1302","last_page":"1306"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11174","display_name":"Pediatric Urology and Nephrology Studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11815","display_name":"Urological Disorders and Treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fetal-alcohol-syndrome","display_name":"fetal alcohol syndrome","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hydronephrosis","display_name":"hydronephrosis","score":0.8730000257492065},{"id":"https://openalex.org/keywords/renal-anomalies","display_name":"renal anomalies","score":0.9539999961853027},{"id":"https://openalex.org/keywords/estradiol-supplementation","display_name":"estradiol supplementation","score":0.8059999942779541},{"id":"https://openalex.org/keywords/testosterone-supplementation","display_name":"testosterone supplementation","score":0.9079999923706055},{"id":"https://openalex.org/keywords/fetal-kidney-development","display_name":"fetal kidney development","score":0.7329999804496765},{"id":"https://openalex.org/keywords/rat-model","display_name":"rat model","score":0.414000004529953}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7923693656921387},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7767359018325806},{"id":"https://openalex.org/C2781040948","wikidata":"https://www.wikidata.org/wiki/Q730877","display_name":"Hydronephrosis","level":3,"score":0.7255035638809204},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6956662535667419},{"id":"https://openalex.org/C2777601104","wikidata":"https://www.wikidata.org/wiki/Q400277","display_name":"Fetal alcohol syndrome","level":3,"score":0.6947633624076843},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.5657666921615601},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.5633549690246582},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.5627235770225525},{"id":"https://openalex.org/C112672928","wikidata":"https://www.wikidata.org/wiki/Q239526","display_name":"Offspring","level":3,"score":0.5481276512145996},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.4877682328224182},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.43550431728363037},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.39892542362213135},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.16777920722961426},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15565213561058044},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004958","descriptor_name":"Estradiol","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D004958","descriptor_name":"Estradiol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006869","descriptor_name":"Hydronephrosis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006869","descriptor_name":"Hydronephrosis","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006869","descriptor_name":"Hydronephrosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063647","descriptor_name":"Fetal Alcohol Spectrum Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0022-3468(97)90307-9","doi":"https://doi.org/10.1016/s0022-3468(97)90307-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0022-3468(97)90307-9","pdf_url":null,"source":{"id":"https://openalex.org/S39924113","display_name":"Journal of Pediatric Surgery","issn_l":"0022-3468","issn":["0022-3468","1531-5037"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Surgery","raw_type":"journal-article"},{"id":"pmid:9314248","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9314248","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pediatric surgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W591646619","https://openalex.org/W1598435453","https://openalex.org/W1970625167","https://openalex.org/W1991145696","https://openalex.org/W2008026041","https://openalex.org/W2014261237","https://openalex.org/W2019978032","https://openalex.org/W2039123692","https://openalex.org/W2046522372","https://openalex.org/W2052487631","https://openalex.org/W2052603928","https://openalex.org/W2067434554","https://openalex.org/W2069176167","https://openalex.org/W2070351756","https://openalex.org/W2072359681","https://openalex.org/W2079002596","https://openalex.org/W2088253805","https://openalex.org/W2094385109","https://openalex.org/W2100506748","https://openalex.org/W2104788447","https://openalex.org/W2403029138","https://openalex.org/W4251169452","https://openalex.org/W4251451199"],"related_works":["https://openalex.org/W2132948948","https://openalex.org/W2010398761","https://openalex.org/W1996749048","https://openalex.org/W1987877869","https://openalex.org/W2009901907","https://openalex.org/W2077260452","https://openalex.org/W1990732470","https://openalex.org/W2039123692","https://openalex.org/W2432960403","https://openalex.org/W2335198367"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}