{"id":"https://openalex.org/W1963533675","doi":"https://doi.org/10.1016/s0303-7207(01)00401-4","title":"Suppression of estrogen-dependent MMP-9 expression by Edpm5, a genetic locus for pituitary tumor growth in rat","display_name":"Suppression of estrogen-dependent MMP-9 expression by Edpm5, a genetic locus for pituitary tumor growth in rat","publication_year":2001,"publication_date":"2001-05-01","ids":{"openalex":"https://openalex.org/W1963533675","doi":"https://doi.org/10.1016/s0303-7207(01)00401-4","mag":"1963533675","pmid":"https://pubmed.ncbi.nlm.nih.gov/11369454"},"language":"en","primary_location":{"id":"doi:10.1016/s0303-7207(01)00401-4","doi":"https://doi.org/10.1016/s0303-7207(01)00401-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0303-7207(01)00401-4","pdf_url":null,"source":{"id":"https://openalex.org/S191044671","display_name":"Molecular and Cellular Endocrinology","issn_l":"0303-7207","issn":["0303-7207","1872-8057"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027469634","display_name":"Russell V Sclafani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177721651","display_name":"Oakland University","ror":"https://ror.org/01ythxj32","country_code":"US","type":"education","lineage":["https://openalex.org/I177721651"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Russell V Sclafani","raw_affiliation_strings":["Department of Biological Sciences, Oakland University, 2200 N, Squirrel Rd, Rochester, MI 48309-4401, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Oakland University, 2200 N, Squirrel Rd, Rochester, MI 48309-4401, USA","institution_ids":["https://openalex.org/I177721651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028320780","display_name":"Douglas L. Wendell","orcid":"https://orcid.org/0000-0001-6884-2229","observed_orcids":["https://orcid.org/0000-0001-6884-2229"]},"institutions":[{"id":"https://openalex.org/I177721651","display_name":"Oakland University","ror":"https://ror.org/01ythxj32","country_code":"US","type":"education","lineage":["https://openalex.org/I177721651"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Douglas L Wendell","raw_affiliation_strings":["Department of Biological Sciences, Oakland University, 2200 N, Squirrel Rd, Rochester, MI 48309-4401, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Oakland University, 2200 N, Squirrel Rd, Rochester, MI 48309-4401, USA","institution_ids":["https://openalex.org/I177721651"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5028320780"],"corresponding_institution_ids":["https://openalex.org/I177721651"],"apc_list":{"value":3510,"currency":"USD","value_usd":3510},"apc_paid":null,"fwci":0.5459,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.65014568,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"176","issue":"1-2","first_page":"145","last_page":"153"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.7656000256538391,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.7656000256538391,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.18359999358654022,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.014999999664723873,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mmp-9","display_name":"MMP-9","score":0.8220000267028809},{"id":"https://openalex.org/keywords/gelatinase","display_name":"gelatinase","score":0.7879999876022339},{"id":"https://openalex.org/keywords/estrogen","display_name":"estrogen","score":0.5099999904632568},{"id":"https://openalex.org/keywords/genetic-loci","display_name":"genetic loci","score":0.42899999022483826},{"id":"https://openalex.org/keywords/quantitative-trait-loci","display_name":"quantitative trait loci","score":0.8420000076293945},{"id":"https://openalex.org/keywords/chromosome-5","display_name":"chromosome 5","score":0.7120000123977661},{"id":"https://openalex.org/keywords/fischer-344-rats","display_name":"F344 rats","score":0.7559999823570251},{"id":"https://openalex.org/keywords/mmp-2","display_name":"MMP-2","score":0.6190000176429749},{"id":"https://openalex.org/keywords/backcrossing","display_name":"backcrossing","score":0.421999990940094}],"concepts":[{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7810701131820679},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7479727864265442},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.7111086845397949},{"id":"https://openalex.org/C72472911","wikidata":"https://www.wikidata.org/wiki/Q2004691","display_name":"Backcrossing","level":3,"score":0.677004337310791},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5644720196723938},{"id":"https://openalex.org/C2781449511","wikidata":"https://www.wikidata.org/wiki/Q864296","display_name":"Pituitary tumors","level":2,"score":0.4241478443145752},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2563888430595398},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.164986252784729},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12110379338264465}],"mesh":[{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004054","descriptor_name":"Diethylstilbestrol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004790","descriptor_name":"Enzyme Induction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004968","descriptor_name":"Estrogens, Non-Steroidal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009928","descriptor_name":"Organ Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010911","descriptor_name":"Pituitary Neoplasms","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D010911","descriptor_name":"Pituitary Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010911","descriptor_name":"Pituitary Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011914","descriptor_name":"Rats, Inbred BN","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011916","descriptor_name":"Rats, Inbred F344","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014599","descriptor_name":"Uterus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014599","descriptor_name":"Uterus","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D014599","descriptor_name":"Uterus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019655","descriptor_name":"Quantitative Trait, Heritable","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020780","descriptor_name":"Matrix Metalloproteinase 9","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D020780","descriptor_name":"Matrix Metalloproteinase 9","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0303-7207(01)00401-4","doi":"https://doi.org/10.1016/s0303-7207(01)00401-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0303-7207(01)00401-4","pdf_url":null,"source":{"id":"https://openalex.org/S191044671","display_name":"Molecular and Cellular Endocrinology","issn_l":"0303-7207","issn":["0303-7207","1872-8057"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Endocrinology","raw_type":"journal-article"},{"id":"pmid:11369454","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11369454","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and cellular endocrinology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.800000011920929,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2241243946","display_name":null,"funder_award_id":"CA71911","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6372340522","display_name":"ESTROGEN-DEPENDENT TUMOR GROWTH AND ANGIOGENESIS","funder_award_id":"5r01ca071911-04","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306082","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W13672921","https://openalex.org/W20949652","https://openalex.org/W1546619202","https://openalex.org/W1588950918","https://openalex.org/W1596270980","https://openalex.org/W1606060992","https://openalex.org/W1619454078","https://openalex.org/W1669342624","https://openalex.org/W1730313527","https://openalex.org/W1800142641","https://openalex.org/W1898415897","https://openalex.org/W1903004489","https://openalex.org/W1964855331","https://openalex.org/W1974018871","https://openalex.org/W1975480650","https://openalex.org/W1976741643","https://openalex.org/W1982365221","https://openalex.org/W1987121453","https://openalex.org/W1991849633","https://openalex.org/W2000953895","https://openalex.org/W2004879090","https://openalex.org/W2011723510","https://openalex.org/W2015809080","https://openalex.org/W2019109370","https://openalex.org/W2029746280","https://openalex.org/W2031993236","https://openalex.org/W2037548154","https://openalex.org/W2038188134","https://openalex.org/W2044214876","https://openalex.org/W2047513027","https://openalex.org/W2061399443","https://openalex.org/W2061744749","https://openalex.org/W2070513969","https://openalex.org/W2071781069","https://openalex.org/W2116505241","https://openalex.org/W2138519685","https://openalex.org/W2147748309","https://openalex.org/W2148191159","https://openalex.org/W2150365936","https://openalex.org/W2153102861","https://openalex.org/W2154675483","https://openalex.org/W2161892290","https://openalex.org/W2163285329","https://openalex.org/W2291887525","https://openalex.org/W2321698502","https://openalex.org/W2331271174","https://openalex.org/W4233353183","https://openalex.org/W4254568502","https://openalex.org/W4313310030"],"related_works":["https://openalex.org/W2029746280","https://openalex.org/W2004879090","https://openalex.org/W2122077278","https://openalex.org/W2091931881","https://openalex.org/W2020236150","https://openalex.org/W269201656","https://openalex.org/W2121648298","https://openalex.org/W1970471136","https://openalex.org/W2564669260","https://openalex.org/W1839418992"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}