{"id":"https://openalex.org/W196352044","doi":"https://doi.org/10.1007/978-1-59745-285-4_42","title":"Primate Models for the Assisted Reproductive Technologies and Embryonic Stem Cell Biology","display_name":"Primate Models for the Assisted Reproductive Technologies and Embryonic Stem Cell Biology","publication_year":2008,"publication_date":"2008-03-06","ids":{"openalex":"https://openalex.org/W196352044","doi":"https://doi.org/10.1007/978-1-59745-285-4_42","mag":"196352044"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-59745-285-4_42","doi":"https://doi.org/10.1007/978-1-59745-285-4_42","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-59745-285-4_42","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sourcebook of Models for Biomedical Research","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W620870677","display_name":"Sourcebook of Models for Biomedical Research"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069135894","display_name":"Don P. Wolf","orcid":"https://orcid.org/0000-0001-6900-2045","observed_orcids":["https://orcid.org/0000-0001-6900-2045"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Don P. Wolf","raw_affiliation_strings":["Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR","institution_ids":["https://openalex.org/I102507086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037802716","display_name":"Shoukhrat M. Mitalipov","orcid":"https://orcid.org/0000-0003-0937-6146","observed_orcids":["https://orcid.org/0000-0003-0937-6146"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shoukhrat Mitalipov","raw_affiliation_strings":["Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR","institution_ids":["https://openalex.org/I102507086"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029364940","display_name":"James Byrne","orcid":"https://orcid.org/0000-0002-2232-292X","observed_orcids":["https://orcid.org/0000-0002-2232-292X"]},"institutions":[{"id":"https://openalex.org/I102507086","display_name":"Oregon National Primate Research Center","ror":"https://ror.org/05fcfqq67","country_code":"US","type":"facility","lineage":["https://openalex.org/I102507086"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James A. Byrne","raw_affiliation_strings":["Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR","institution_ids":["https://openalex.org/I102507086"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I102507086"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.04756469,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"397","last_page":"404"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.040800001472234726,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.013000000268220901,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nonhuman-primates","display_name":"non-human primates","score":0.9789999723434448},{"id":"https://openalex.org/keywords/assisted-reproductive-technology","display_name":"assisted reproduction","score":0.9490000009536743},{"id":"https://openalex.org/keywords/embryonic-stem-cells","display_name":"embryonic stem cells","score":0.9700000286102295},{"id":"https://openalex.org/keywords/somatic-cell-nuclear-transfer","display_name":"somatic cell nuclear transfer","score":0.968999981880188},{"id":"https://openalex.org/keywords/therapeutic-cloning","display_name":"therapeutic cloning","score":0.8619999885559082},{"id":"https://openalex.org/keywords/infertility","display_name":"infertility","score":0.5440000295639038},{"id":"https://openalex.org/keywords/contraceptive-development","display_name":"contraceptive development","score":0.7429999709129333},{"id":"https://openalex.org/keywords/hiv-vaccine-development","display_name":"HIV vaccine development","score":0.8080000281333923},{"id":"https://openalex.org/keywords/gene-targeting","display_name":"gene targeting","score":0.5509999990463257},{"id":"https://openalex.org/keywords/neurodegenerative-disease-models","display_name":"neurodegenerative disease models","score":0.9070000052452087},{"id":"https://openalex.org/keywords/rhesus-macaques","display_name":"rhesus monkeys","score":0.9160000085830688},{"id":"https://openalex.org/keywords/cynomolgus-macaques","display_name":"cynomolgus macaques","score":0.9980000257492065},{"id":"https://openalex.org/keywords/baboons","display_name":"baboons","score":0.9290000200271606},{"id":"https://openalex.org/keywords/old-world-monkeys","display_name":"Old World monkeys","score":0.7670000195503235},{"id":"https://openalex.org/keywords/animal-models","display_name":"animal models","score":0.4300000071525574}],"concepts":[{"id":"https://openalex.org/C202438428","wikidata":"https://www.wikidata.org/wiki/Q1939923","display_name":"Somatic cell nuclear transfer","level":5,"score":0.907760739326477},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7374483346939087},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.6395496129989624},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.579940676689148},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5554696321487427},{"id":"https://openalex.org/C134305767","wikidata":"https://www.wikidata.org/wiki/Q725508","display_name":"Somatic cell","level":3,"score":0.49683430790901184},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.4331579804420471},{"id":"https://openalex.org/C2777688143","wikidata":"https://www.wikidata.org/wiki/Q179399","display_name":"Infertility","level":3,"score":0.4105573296546936},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3685608506202698},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3365476131439209},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.28181350231170654},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1866162121295929},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.17154639959335327},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.15996503829956055},{"id":"https://openalex.org/C2778177303","wikidata":"https://www.wikidata.org/wiki/Q227717","display_name":"Blastocyst","level":4,"score":0.10702186822891235},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-59745-285-4_42","doi":"https://doi.org/10.1007/978-1-59745-285-4_42","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-59745-285-4_42","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sourcebook of Models for Biomedical Research","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":114,"referenced_works":["https://openalex.org/W30641381","https://openalex.org/W55178933","https://openalex.org/W225971440","https://openalex.org/W407737309","https://openalex.org/W565240797","https://openalex.org/W579436695","https://openalex.org/W638998111","https://openalex.org/W1483929886","https://openalex.org/W1584367137","https://openalex.org/W1593777176","https://openalex.org/W1599568627","https://openalex.org/W1601995899","https://openalex.org/W1972044718","https://openalex.org/W1976063335","https://openalex.org/W1977680286","https://openalex.org/W1979426146","https://openalex.org/W1980568133","https://openalex.org/W1982960471","https://openalex.org/W1991099871","https://openalex.org/W2005708269","https://openalex.org/W2006134329","https://openalex.org/W2009771793","https://openalex.org/W2015141378","https://openalex.org/W2016193646","https://openalex.org/W2018650543","https://openalex.org/W2020532383","https://openalex.org/W2021127328","https://openalex.org/W2022214898","https://openalex.org/W2024784264","https://openalex.org/W2025795063","https://openalex.org/W2032607956","https://openalex.org/W2033509824","https://openalex.org/W2039188344","https://openalex.org/W2041695960","https://openalex.org/W2043173210","https://openalex.org/W2045652849","https://openalex.org/W2045899482","https://openalex.org/W2046454221","https://openalex.org/W2048465868","https://openalex.org/W2050384573","https://openalex.org/W2053251564","https://openalex.org/W2054259989","https://openalex.org/W2059759528","https://openalex.org/W2063914392","https://openalex.org/W2067209270","https://openalex.org/W2068099602","https://openalex.org/W2069009153","https://openalex.org/W2071342278","https://openalex.org/W2072773727","https://openalex.org/W2073179302","https://openalex.org/W2075114334","https://openalex.org/W2076134489","https://openalex.org/W2081180110","https://openalex.org/W2082532506","https://openalex.org/W2083449820","https://openalex.org/W2083763893","https://openalex.org/W2085403618","https://openalex.org/W2086446960","https://openalex.org/W2086943348","https://openalex.org/W2086968682","https://openalex.org/W2091652308","https://openalex.org/W2096402693","https://openalex.org/W2097595052","https://openalex.org/W2101879593","https://openalex.org/W2102974928","https://openalex.org/W2106246155","https://openalex.org/W2109744103","https://openalex.org/W2110795217","https://openalex.org/W2121110826","https://openalex.org/W2122694737","https://openalex.org/W2125286104","https://openalex.org/W2126561768","https://openalex.org/W2129400498","https://openalex.org/W2130388431","https://openalex.org/W2133501984","https://openalex.org/W2136235061","https://openalex.org/W2140181784","https://openalex.org/W2141977208","https://openalex.org/W2142223860","https://openalex.org/W2145336293","https://openalex.org/W2146658962","https://openalex.org/W2157087132","https://openalex.org/W2157196533","https://openalex.org/W2157614773","https://openalex.org/W2159066033","https://openalex.org/W2163192130","https://openalex.org/W2163719762","https://openalex.org/W2164469054","https://openalex.org/W2168519381","https://openalex.org/W2170928461","https://openalex.org/W2218216224","https://openalex.org/W2269901536","https://openalex.org/W2309379472","https://openalex.org/W2345796415","https://openalex.org/W2402931260","https://openalex.org/W2404777357","https://openalex.org/W2408899914","https://openalex.org/W2409254376","https://openalex.org/W2410740457","https://openalex.org/W2411477663","https://openalex.org/W2411628291","https://openalex.org/W2412139092","https://openalex.org/W2412351560","https://openalex.org/W2414735082","https://openalex.org/W2414985157","https://openalex.org/W2416974316","https://openalex.org/W2417247722","https://openalex.org/W2418130164","https://openalex.org/W2465562151","https://openalex.org/W2470872152","https://openalex.org/W2473120836","https://openalex.org/W2493610840","https://openalex.org/W3022537861","https://openalex.org/W4230250704"],"related_works":["https://openalex.org/W2219618913","https://openalex.org/W3033926588","https://openalex.org/W2412351560","https://openalex.org/W4410108158","https://openalex.org/W1562515060","https://openalex.org/W2588765419","https://openalex.org/W2087629484","https://openalex.org/W1972136882","https://openalex.org/W2136235061","https://openalex.org/W1996253505"],"abstract_inverted_index":{"Nonhuman":[0],"primates":[1],"(NHPs)":[2],"represent":[3],"clinically":[4],"relevant":[5,27,99],"animal":[6],"models":[7,25,127],"used":[8,64,81],"in":[9,65,82,96,119,137,142,166],"studies":[10,159],"on":[11],"the":[12,20,34,66,83,102,113,139],"etiology":[13,35],"and":[14,36,40,78,118,141,154,157],"treatment":[15,37],"of":[16,22,38,46,51,68,85,105,115,128],"human":[17],"diseases.":[18,132],"In":[19],"context":[21],"reproduction,":[23],"NHP":[24,135],"are":[26,63],"to":[28,43,100,111,124],"research":[29],"interests":[30],"as":[31,33],"diverse":[32],"infertility":[39],"contraceptive":[41],"development":[42,77],"an":[44],"evaluation":[45],"cell":[47,91],"or":[48,107],"tissue-based":[49],"therapies":[50],"disease":[52],"employing":[53],"embryonic":[54,144],"stem":[55,145],"cell-derived":[56],"phenotypes.":[57],"The":[58],"assisted":[59],"reproductive":[60],"technologies":[61],"(ARTs)":[62],"production":[67,84],"animals":[69,88],"carrying":[70],"desired":[71],"MHC":[72],"alleles":[73],"for":[74],"HIV":[75],"vaccine":[76],"could":[79],"be":[80,164],"genetically":[86,129],"identical":[87],"by":[89],"somatic":[90],"nuclear":[92],"transfer":[93],"(SCNT).":[94],"SCNT":[95],"turn":[97],"is":[98],"rescuing":[101],"unique":[103],"genetics":[104],"aging":[106],"even":[108],"deceased":[109],"animals,":[110],"testing":[112],"efficacy":[114],"therapeutic":[116],"cloning,":[117],"combination":[120],"with":[121,160],"gene":[122],"targeting,":[123],"creating":[125],"monkey":[126],"based,":[130],"neurodegenerative":[131],"Since":[133],"most":[134],"experience":[136],"applying":[138],"ARTs":[140],"deriving":[143],"cells":[146],"(ESCs)":[147],"involves":[148],"Old":[149],"World":[150],"monkeys,":[151],"principally":[152],"rhesus":[153],"cynomolgus":[155],"macaques":[156],"baboons,":[158],"these":[161],"species":[162],"will":[163],"featured":[165],"this":[167],"chapter.":[168]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}
