{"id":"https://openalex.org/W1958192554","doi":"https://doi.org/10.1186/s12870-015-0625-z","title":"Development of marker-free transgenic Jatropha curcas producing curcin-deficient seeds through endosperm-specific RNAi-mediated gene silencing","display_name":"Development of marker-free transgenic Jatropha curcas producing curcin-deficient seeds through endosperm-specific RNAi-mediated gene silencing","publication_year":2015,"publication_date":"2015-10-08","ids":{"openalex":"https://openalex.org/W1958192554","doi":"https://doi.org/10.1186/s12870-015-0625-z","mag":"1958192554","pmid":"https://pubmed.ncbi.nlm.nih.gov/26450182","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4599812"},"language":"en","primary_location":{"id":"doi:10.1186/s12870-015-0625-z","doi":"https://doi.org/10.1186/s12870-015-0625-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12870-015-0625-z","pdf_url":"https://bmcplantbiol.biomedcentral.com/counter/pdf/10.1186/s12870-015-0625-z","source":{"id":"https://openalex.org/S6444338","display_name":"BMC Plant Biology","issn_l":"1471-2229","issn":["1471-2229"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Plant Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcplantbiol.biomedcentral.com/counter/pdf/10.1186/s12870-015-0625-z","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101471357","display_name":"Keyu Gu","orcid":"https://orcid.org/0000-0002-3300-1873","observed_orcids":["https://orcid.org/0000-0002-3300-1873"]},"institutions":[{"id":"https://openalex.org/I162266279","display_name":"Temasek Life Sciences Laboratory","ror":"https://ror.org/0574eex11","country_code":"SG","type":"facility","lineage":["https://openalex.org/I162266279"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Keyu Gu","raw_affiliation_strings":["Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore. keyu@tll.org.sg","Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore. keyu@tll.org.sg","institution_ids":["https://openalex.org/I162266279","https://openalex.org/I165932596"]},{"raw_affiliation_string":"Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore","institution_ids":["https://openalex.org/I162266279","https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100891771","display_name":"Dongsheng Tian","orcid":"https://orcid.org/0009-0008-9471-1087","observed_orcids":["https://orcid.org/0009-0008-9471-1087"]},"institutions":[{"id":"https://openalex.org/I162266279","display_name":"Temasek Life Sciences Laboratory","ror":"https://ror.org/0574eex11","country_code":"SG","type":"facility","lineage":["https://openalex.org/I162266279"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Dongsheng Tian","raw_affiliation_strings":["Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore. tiands@tll.org.sg","Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore. tiands@tll.org.sg","institution_ids":["https://openalex.org/I162266279","https://openalex.org/I165932596"]},{"raw_affiliation_string":"Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore","institution_ids":["https://openalex.org/I162266279","https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003809973","display_name":"Huizhu Mao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I162266279","display_name":"Temasek Life Sciences Laboratory","ror":"https://ror.org/0574eex11","country_code":"SG","type":"facility","lineage":["https://openalex.org/I162266279"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Huizhu Mao","raw_affiliation_strings":["Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore. maohz@tll.org.sg","Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore. maohz@tll.org.sg","institution_ids":["https://openalex.org/I162266279","https://openalex.org/I165932596"]},{"raw_affiliation_string":"Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore","institution_ids":["https://openalex.org/I162266279","https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008630001","display_name":"Lifang Wu","orcid":"https://orcid.org/0000-0002-0589-4803","observed_orcids":["https://orcid.org/0000-0002-0589-4803"]},"institutions":[{"id":"https://openalex.org/I162266279","display_name":"Temasek Life Sciences Laboratory","ror":"https://ror.org/0574eex11","country_code":"SG","type":"facility","lineage":["https://openalex.org/I162266279"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2802624667","display_name":"Hefei Institutes of Physical Science","ror":"https://ror.org/046n57345","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2802624667"]}],"countries":["CN","SG"],"is_corresponding":false,"raw_author_name":"Lifang Wu","raw_affiliation_strings":["Present address: Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, Anhui, China. lfwu@ipp.ac.cn","Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore. lfwu@ipp.ac.cn","Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Present address: Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, Anhui, China. lfwu@ipp.ac.cn","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I2802624667"]},{"raw_affiliation_string":"Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore. lfwu@ipp.ac.cn","institution_ids":["https://openalex.org/I162266279","https://openalex.org/I165932596"]},{"raw_affiliation_string":"Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore","institution_ids":["https://openalex.org/I162266279","https://openalex.org/I165932596"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089758234","display_name":"Zhongchao Yin","orcid":"https://orcid.org/0000-0001-8519-5879","observed_orcids":["https://orcid.org/0000-0001-8519-5879"]},"institutions":[{"id":"https://openalex.org/I162266279","display_name":"Temasek Life Sciences Laboratory","ror":"https://ror.org/0574eex11","country_code":"SG","type":"facility","lineage":["https://openalex.org/I162266279"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Zhongchao Yin","raw_affiliation_strings":["Department of Biological Sciences, National University of Singapore, 14 Science Drive, Singapore, 117543, Republic of Singapore. yinzc@tll.org.sg","School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Republic of Singapore. yinzc@tll.org.sg","Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore. yinzc@tll.org.sg","Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, 14 Science Drive, Singapore, 117543, Republic of Singapore. yinzc@tll.org.sg","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Republic of Singapore. yinzc@tll.org.sg","institution_ids":["https://openalex.org/I172675005"]},{"raw_affiliation_string":"Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore. yinzc@tll.org.sg","institution_ids":["https://openalex.org/I162266279","https://openalex.org/I165932596"]},{"raw_affiliation_string":"Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Republic of Singapore","institution_ids":["https://openalex.org/I162266279","https://openalex.org/I165932596"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5089758234"],"corresponding_institution_ids":["https://openalex.org/I162266279","https://openalex.org/I165932596","https://openalex.org/I172675005"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":{"value":3090,"currency":"USD","value_usd":3090},"fwci":3.7722,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.92074935,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"15","issue":"1","first_page":"242","last_page":"242"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11426","display_name":"Genetically Modified Organisms Research","score":0.3061999976634979,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11426","display_name":"Genetically Modified Organisms Research","score":0.3061999976634979,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12856","display_name":"Transgenic Plants and Applications","score":0.29100000858306885,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10240","display_name":"Plant tissue culture and regeneration","score":0.12430000305175781,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/jatropha-curcas","display_name":"Jatropha curcas","score":1.0},{"id":"https://openalex.org/keywords/curcin","display_name":"curcin","score":0.7680000066757202},{"id":"https://openalex.org/keywords/ribosome-inactivating-proteins","display_name":"ribosome-inactivating proteins","score":0.800000011920929},{"id":"https://openalex.org/keywords/rna-interference","display_name":"RNA interference","score":0.8230000138282776},{"id":"https://openalex.org/keywords/marker-free-transgenic-plants","display_name":"marker-free transgenic plants","score":0.9660000205039978},{"id":"https://openalex.org/keywords/cre-loxp-system","display_name":"Cre-loxP system","score":0.8529999852180481},{"id":"https://openalex.org/keywords/phorbol-ester","display_name":"phorbol ester","score":0.8019999861717224},{"id":"https://openalex.org/keywords/seed-toxicity","display_name":"seed toxicity","score":0.8230000138282776},{"id":"https://openalex.org/keywords/biodiesel-feedstock","display_name":"biodiesel feedstock","score":0.7279999852180481}],"concepts":[{"id":"https://openalex.org/C2777247137","wikidata":"https://www.wikidata.org/wiki/Q74644","display_name":"Jatropha curcas","level":2,"score":0.8936948180198669},{"id":"https://openalex.org/C113442657","wikidata":"https://www.wikidata.org/wiki/Q25624","display_name":"Endosperm","level":2,"score":0.8811171650886536},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.8493562936782837},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8445791006088257},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5842600464820862},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.5601365566253662},{"id":"https://openalex.org/C122172344","wikidata":"https://www.wikidata.org/wiki/Q1503477","display_name":"Genetically modified crops","level":4,"score":0.5189309120178223},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.426744282245636},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4241466522216797},{"id":"https://openalex.org/C177955015","wikidata":"https://www.wikidata.org/wiki/Q5532936","display_name":"Genetically modified rice","level":5,"score":0.4199313521385193},{"id":"https://openalex.org/C2778733479","wikidata":"https://www.wikidata.org/wiki/Q152986","display_name":"Jatropha","level":4,"score":0.4152635335922241},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.30738139152526855},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2511880397796631},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.22707757353782654},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1412149965763092},{"id":"https://openalex.org/C52896960","wikidata":"https://www.wikidata.org/wiki/Q167947","display_name":"Biodiesel","level":3,"score":0.14047059416770935},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009928","descriptor_name":"Organ Specificity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012639","descriptor_name":"Seeds","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015139","descriptor_name":"Blotting, Southern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015152","descriptor_name":"Blotting, Northern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D031286","descriptor_name":"Jatropha","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054789","descriptor_name":"Ribosome Inactivating Proteins, Type 1","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D056625","descriptor_name":"Endosperm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1186/s12870-015-0625-z","doi":"https://doi.org/10.1186/s12870-015-0625-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12870-015-0625-z","pdf_url":"https://bmcplantbiol.biomedcentral.com/counter/pdf/10.1186/s12870-015-0625-z","source":{"id":"https://openalex.org/S6444338","display_name":"BMC Plant Biology","issn_l":"1471-2229","issn":["1471-2229"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Plant Biology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3576449","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4599812","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4599812","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4599812","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Plant Biol","raw_type":"Text"},{"id":"pmid:26450182","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26450182","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC plant biology","raw_type":"Journal Article"},{"id":"pmh:oai:scholarbank.nus.edu.sg:10635/174278","doi":null,"is_oa":false,"landing_page_url":"https://scholarbank.nus.edu.sg/handle/10635/174278","pdf_url":null,"source":{"id":"https://openalex.org/S7407052290","display_name":"National University of Singapore","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Unpaywall 20200831","raw_type":"Article"},{"id":"pmh:oai:dr.ntu.edu.sg:10356/80985","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10220/39033","pdf_url":null,"source":{"id":"https://openalex.org/S4306402609","display_name":"DR-NTU (Nanyang Technological University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I172675005","host_organization_name":"Nanyang Technological University","host_organization_lineage":["https://openalex.org/I172675005"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1186/s12870-015-0625-z","doi":"https://doi.org/10.1186/s12870-015-0625-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12870-015-0625-z","pdf_url":"https://bmcplantbiol.biomedcentral.com/counter/pdf/10.1186/s12870-015-0625-z","source":{"id":"https://openalex.org/S6444338","display_name":"BMC Plant Biology","issn_l":"1471-2229","issn":["1471-2229"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Plant Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.9208999872207642,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320698","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49"},{"id":"https://openalex.org/F4320323603","display_name":"Universidad de la Rep\u00fablica Uruguay","ror":"https://ror.org/030bbe882"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1958192554.pdf","grobid_xml":"https://content.openalex.org/works/W1958192554.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W114250974","https://openalex.org/W1500657464","https://openalex.org/W1975747937","https://openalex.org/W1982047966","https://openalex.org/W1986508375","https://openalex.org/W1986979018","https://openalex.org/W1996934880","https://openalex.org/W2007993460","https://openalex.org/W2021816938","https://openalex.org/W2043129367","https://openalex.org/W2067684322","https://openalex.org/W2073103775","https://openalex.org/W2081942920","https://openalex.org/W2086233890","https://openalex.org/W2086557880","https://openalex.org/W2093280274","https://openalex.org/W2101514630","https://openalex.org/W2109468438","https://openalex.org/W2127204797","https://openalex.org/W2128635872","https://openalex.org/W2133459663","https://openalex.org/W2136861504","https://openalex.org/W2144634347","https://openalex.org/W2152885242","https://openalex.org/W2157343715","https://openalex.org/W2159952426","https://openalex.org/W2160646289","https://openalex.org/W2165883898","https://openalex.org/W2170729665","https://openalex.org/W2171086576","https://openalex.org/W2171820561","https://openalex.org/W2291855029","https://openalex.org/W2397160731","https://openalex.org/W2804007336"],"related_works":["https://openalex.org/W2564128812","https://openalex.org/W2067684322","https://openalex.org/W7162711417","https://openalex.org/W2353753768","https://openalex.org/W2387481302","https://openalex.org/W7120763854","https://openalex.org/W2021816938","https://openalex.org/W2081942920","https://openalex.org/W7164039400","https://openalex.org/W7162707791"],"abstract_inverted_index":{"BACKGROUND:":[0],"Jatropha":[1],"curcas":[2],"L.":[3],"is":[4,13,78,91],"a":[5,103,108,299],"potential":[6],"biofuel":[7],"plant":[8],"and":[9,32,43,46,52,107,118,167,173,186,203,224,267,272,291,309],"its":[10],"seed":[11,41],"oil":[12],"suitable":[14],"for":[15,113,258,301],"biodiesel":[16],"production.":[17],"Despite":[18],"this":[19,296],"promising":[20],"application,":[21],"jatropha":[22,50,69,307],"seeds":[23,188,221,293,308],"contain":[24],"two":[25,147],"major":[26],"toxic":[27],"components,":[28],"namely":[29],"phorbol":[30],"esters":[31],"curcins.":[33],"These":[34],"compounds":[35],"would":[36],"reduce":[37],"commercial":[38],"value":[39],"of":[40,135,139,149,155,163,170,184,201,219,222,232,283,304,314],"cake":[42],"raise":[44],"safety":[45,312],"environment":[47],"concerns":[48,313],"on":[49,321],"plantation":[51],"processing.":[53],"Curcins":[54],"are":[55],"Type":[56],"I":[57],"ribosome":[58],"inactivating":[59],"proteins.":[60],"Several":[61],"curcin":[62],"genes":[63,317],"have":[64],"been":[65],"identified":[66,79],"in":[67,84,94,132,182,198,216,262,280,295,306,318],"the":[68,73,87,129,133,195,210,217,230,233,242,249,259,281,302,311,315,322],"genome.":[70],"Among":[71],"which,":[72],"Curcin":[74,88],"1":[75],"(C1)":[76],"gene":[77,115,131,235,261],"to":[80,120,126],"be":[81],"specifically":[82,127,237],"expressed":[83,93],"endosperm,":[85],"whereas":[86,153],"2A":[89],"(C2A)":[90],"mainly":[92],"young":[95,199],"leaves.":[96],"RESULTS:":[97],"A":[98],"marker-free":[99,122,150,164,288],"RNAi":[100,111,124,151,165,250,256],"construct":[101],"carrying":[102],"\u03b2-estradiol-regulated":[104],"Cre/loxP":[105],"system":[106],"C1":[109,114,130,179,211,234,254,260,270,273],"promoter-driven":[110,255],"cassette":[112,166,257],"was":[116,189,236,265],"made":[117],"used":[119],"generate":[121],"transgenic":[123,140,263,284,289,319],"plants":[125,154,205,264,290,320],"silence":[128],"endosperm":[134,183,218,282],"J.":[136,285],"curcas.":[137,286],"Plants":[138],"line":[141],"L1,":[142],"derived":[143,157],"from":[144,158,248],"T0-1,":[145],"carry":[146],"copies":[148,169],"cassette,":[152],"L35,":[156],"T0-35,":[159],"harbored":[160],"one":[161],"copy":[162],"three":[168],"closely":[171],"linked":[172],"yet":[174],"truncated":[175],"Hpt":[176],"genes.":[177],"The":[178,226,253,287],"protein":[180],"content":[181],"L1":[185,223],"L35":[187],"greatly":[190,276],"reduced":[191],"or":[192,239,278],"undetectable,":[193],"while":[194],"C2A":[196],"proteins":[197,274],"leaves":[200],"T0-1":[202],"T0-35":[204],"were":[206,214,275],"unaffected.":[207],"In":[208],"addition,":[209],"mRNA":[212],"transcripts":[213,271],"undetectable":[215],"T3":[220],"L35.":[225],"results":[227],"demonstrated":[228],"that":[229],"expression":[231],"down-regulated":[238,277],"silenced":[240,279],"by":[241],"double-stranded":[243],"RNA-mediated":[244],"RNA":[245],"interference":[246],"generated":[247],"cassette.":[251],"CONCLUSION:":[252],"functional":[266],"heritable.":[268],"Both":[269],"curcin-deficient":[292],"developed":[294],"study":[297],"provided":[298],"solution":[300],"toxicity":[303],"curcins":[305],"addressed":[310],"marker":[316],"environments.":[323]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}