{"id":"https://openalex.org/W19528859","doi":null,"title":"Asparagus racemosus Willd (Liliaceae) ameliorates early diabetic nephropathy in STZ induced diabetic rats.","display_name":"Asparagus racemosus Willd (Liliaceae) ameliorates early diabetic nephropathy in STZ induced diabetic rats.","publication_year":2012,"publication_date":"2012-07-01","ids":{"openalex":"https://openalex.org/W19528859","mag":"19528859","pmid":"https://pubmed.ncbi.nlm.nih.gov/22822526"},"language":"en","primary_location":{"id":"pmid:22822526","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22822526","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian journal of experimental biology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067594897","display_name":"Rahul Somania","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rahul Somania","raw_affiliation_strings":["Department of Pharmacology, Smt. Kashibai Navale College of Pharmacy, Pune 411 048, India. rahulsomani2001@yahoo.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Smt. Kashibai Navale College of Pharmacy, Pune 411 048, India. rahulsomani2001@yahoo.com","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111777437","display_name":"Abhay Kumar Singhai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Abhay Kumar Singhai","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005954773","display_name":"Prashant P. Shivgunde","orcid":"https://orcid.org/0000-0001-9812-8405","observed_orcids":["https://orcid.org/0000-0001-9812-8405"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Prashant Shivgunde","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5078673250","display_name":"Dilpesh P. Jain","orcid":"https://orcid.org/0000-0003-1590-4902","observed_orcids":["https://orcid.org/0000-0003-1590-4902"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dilpesh Jain","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4714,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.88144096,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"50","issue":"7","first_page":"469","last_page":"75"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.8051999807357788,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.8051999807357788,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.10189999639987946,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12298","display_name":"Phytochemicals and Medicinal Plants","score":0.04470000043511391,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asparagus-racemosus","display_name":"Asparagus racemosus","score":1.0},{"id":"https://openalex.org/keywords/diabetic-nephropathy","display_name":"diabetic nephropathy","score":0.9890000224113464},{"id":"https://openalex.org/keywords/streptozotocin-induced-diabetes","display_name":"streptozotocin-induced diabetes","score":0.9959999918937683},{"id":"https://openalex.org/keywords/ethanolic-plant-extract","display_name":"ethanolic plant extract","score":0.9520000219345093},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.6430000066757202},{"id":"https://openalex.org/keywords/microalbuminuria","display_name":"microalbuminuria","score":0.9459999799728394},{"id":"https://openalex.org/keywords/renal-hypertrophy","display_name":"renal hypertrophy","score":0.8309999704360962},{"id":"https://openalex.org/keywords/hyperfiltration","display_name":"hyperfiltration","score":0.8560000061988831},{"id":"https://openalex.org/keywords/basement-membrane-thickening","display_name":"basement membrane thickening","score":0.7739999890327454},{"id":"https://openalex.org/keywords/mesangial-proliferation","display_name":"mesangial cell proliferation","score":0.9810000061988831},{"id":"https://openalex.org/keywords/plasma-glucose","display_name":"plasma glucose","score":0.550000011920929},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.7699999809265137}],"concepts":[{"id":"https://openalex.org/C2778223594","wikidata":"https://www.wikidata.org/wiki/Q4807702","display_name":"Asparagus racemosus","level":3,"score":0.9242846965789795},{"id":"https://openalex.org/C2779922275","wikidata":"https://www.wikidata.org/wiki/Q1129105","display_name":"Diabetic nephropathy","level":3,"score":0.7395446300506592},{"id":"https://openalex.org/C2779280383","wikidata":"https://www.wikidata.org/wiki/Q257331","display_name":"Streptozotocin","level":3,"score":0.695116400718689},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6320970058441162},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5730258822441101},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5635440349578857},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5592263340950012},{"id":"https://openalex.org/C2781203188","wikidata":"https://www.wikidata.org/wiki/Q1676817","display_name":"Microalbuminuria","level":3,"score":0.45744654536247253},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.4455629885196686},{"id":"https://openalex.org/C2909763481","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Renal Hypertrophy","level":4,"score":0.4330364465713501},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.2412494719028473},{"id":"https://openalex.org/C2779158651","wikidata":"https://www.wikidata.org/wiki/Q188840","display_name":"Medicinal plants","level":2,"score":0.15520861744880676}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003921","descriptor_name":"Diabetes Mellitus, Experimental","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003928","descriptor_name":"Diabetic Nephropathies","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D013311","descriptor_name":"Streptozocin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D027761","descriptor_name":"Asparagus Plant","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:22822526","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22822526","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian journal of experimental biology","raw_type":"Journal Article"},{"id":"mag:19528859","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22822526","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1566830427","https://openalex.org/W1659912652","https://openalex.org/W1775749144","https://openalex.org/W1909254787","https://openalex.org/W1968446955","https://openalex.org/W1970585602","https://openalex.org/W1975609579","https://openalex.org/W1983310681","https://openalex.org/W1986639245","https://openalex.org/W1995428435","https://openalex.org/W1998505427","https://openalex.org/W2000519471","https://openalex.org/W2002389866","https://openalex.org/W2009302654","https://openalex.org/W2010451625","https://openalex.org/W2011801069","https://openalex.org/W2031484324","https://openalex.org/W2042868822","https://openalex.org/W2047241964","https://openalex.org/W2060230815","https://openalex.org/W2067826679","https://openalex.org/W2070580300","https://openalex.org/W2079837239","https://openalex.org/W2086321305","https://openalex.org/W2086786184","https://openalex.org/W2099088285","https://openalex.org/W2118313918","https://openalex.org/W2118393060","https://openalex.org/W2119063449","https://openalex.org/W2120739966","https://openalex.org/W2121509432","https://openalex.org/W2146328747","https://openalex.org/W2146911942","https://openalex.org/W2153631564","https://openalex.org/W2266929960","https://openalex.org/W2275246769","https://openalex.org/W2396968486","https://openalex.org/W2404450421","https://openalex.org/W2415969407","https://openalex.org/W4254523290"],"related_works":["https://openalex.org/W2181953783","https://openalex.org/W6893473554","https://openalex.org/W2659008555","https://openalex.org/W2503665243","https://openalex.org/W4281260118","https://openalex.org/W2937406983","https://openalex.org/W2802923126","https://openalex.org/W1982113154","https://openalex.org/W3163945843","https://openalex.org/W2142185775"],"abstract_inverted_index":{"Diabetic":[0],"nephropathy":[1,65],"is":[2],"a":[3,81],"major":[4],"\"microvascular\"":[5],"complication":[6],"of":[7,13,42,55,76,84,95,166,179],"diabetes,":[8],"differs":[9],"from":[10,24],"other":[11],"causes":[12],"chronic":[14],"kidney":[15],"diseases":[16],"in":[17,66,126,152,161,176],"its":[18],"predictability,":[19],"with":[20,73,99],"well-defined":[21],"functional":[22],"progression":[23],"hyperfiltration":[25],"to":[26,28,30,38,61],"micro-":[27],"macroalbuminuria":[29],"renal":[31,128],"failure.":[32],"The":[33,93],"present":[34],"study":[35,168],"was":[36,59,97],"undertaken":[37],"investigate":[39],"the":[40,127,177],"effect":[41,175],"Asparagus":[43,77],"racemosus":[44,78,104,172],"Willd":[45],"(Liliaceae)":[46],"on":[47],"streptozotocin-induced":[48],"early":[49,63],"diabetic":[50,64,100,153,180],"nephropathy.":[51],"Single":[52],"i.p":[53],"injection":[54],"streptozotocin":[56],"(55":[57],"mg/kg)":[58],"administered":[60],"induce":[62],"Wistar":[67],"rats":[68],"and":[69,86,115,123,144],"thereafter":[70],"treated":[71,163],"orally":[72],"ethanolic":[74],"extract":[75,96],"(EEAR)":[79],"at":[80],"dose":[82],"level":[83],"100":[85],"250":[87],"mg/kg":[88],"daily":[89],"for":[90],"4":[91],"weeks.":[92],"efficacy":[94],"compared":[98],"control":[101],"rats.":[102],"A.":[103,171],"treatment":[105,178],"significantly":[106],"decreased":[107],"plasma":[108],"glucose,":[109],"creatinine,":[110],"urea":[111],"nitrogen,":[112],"total":[113],"cholesterol":[114],"triglyceride":[116],"levels.":[117],"Renal":[118],"hypertrophy,":[119],"polyuria,":[120],"hyperfiltration,":[121],"microalbuminuria":[122],"abnormal":[124],"changes":[125,158],"tissue":[129],"as":[130,132],"well":[131],"oxidative":[133],"stress":[134],"were":[135,150,159],"effectively":[136],"attenuated":[137],"by":[138],"EEAR":[139,162],"treatment.":[140],"Basement":[141],"membrane":[142],"thickening":[143],"mesangial":[145],"proliferation":[146],"formation":[147],"without":[148],"nodules":[149],"seen":[151],"rats,":[154],"whereas":[155],"these":[156],"structural":[157],"reduced":[160],"groups.":[164],"Results":[165],"this":[167],"suggested":[169],"that":[170],"has":[173],"beneficial":[174]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}