{"id":"https://openalex.org/W1950995263","doi":"https://doi.org/10.7863/jum.1994.13.8.613","title":"Left ventricular echogenic focus in the fetal heart: pathologic correlation.","display_name":"Left ventricular echogenic focus in the fetal heart: pathologic correlation.","publication_year":1994,"publication_date":"1994-08-01","ids":{"openalex":"https://openalex.org/W1950995263","doi":"https://doi.org/10.7863/jum.1994.13.8.613","mag":"1950995263","pmid":"https://pubmed.ncbi.nlm.nih.gov/7933029"},"language":"en","primary_location":{"id":"doi:10.7863/jum.1994.13.8.613","doi":"https://doi.org/10.7863/jum.1994.13.8.613","is_oa":false,"landing_page_url":"https://doi.org/10.7863/jum.1994.13.8.613","pdf_url":null,"source":{"id":"https://openalex.org/S111362775","display_name":"Journal of Ultrasound in Medicine","issn_l":"0278-4297","issn":["0278-4297","1550-9613"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Ultrasound in Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011047705","display_name":"Douglas L. Brown","orcid":"https://orcid.org/0000-0002-7636-9168","observed_orcids":["https://orcid.org/0000-0002-7636-9168"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D L Brown","raw_affiliation_strings":["Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027859165","display_name":"Drucilla Jane Roberts","orcid":"https://orcid.org/0000-0002-9104-6674","observed_orcids":["https://orcid.org/0000-0002-9104-6674"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D J Roberts","raw_affiliation_strings":["Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110903553","display_name":"Wayne A. Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W A Miller","raw_affiliation_strings":["Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4100,"currency":"USD","value_usd":4100},"apc_paid":null,"fwci":2.6367,"has_fulltext":false,"cited_by_count":93,"citation_normalized_percentile":{"value":0.88455719,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"13","issue":"8","first_page":"613","last_page":"616"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.44429999589920044,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.44429999589920044,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":0.17149999737739563,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12552","display_name":"Fetal and Pediatric Neurological Disorders","score":0.1071000024676323,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/echogenic-foci","display_name":"echogenic foci","score":0.7350000143051147},{"id":"https://openalex.org/keywords/fetal-left-ventricle","display_name":"fetal left ventricle","score":0.9089999794960022},{"id":"https://openalex.org/keywords/fetal-echocardiography","display_name":"fetal echocardiography","score":0.7739999890327454},{"id":"https://openalex.org/keywords/down-syndrome","display_name":"Down syndrome","score":0.9440000057220459},{"id":"https://openalex.org/keywords/aneuploidy","display_name":"aneuploidy","score":0.9369999766349792},{"id":"https://openalex.org/keywords/normal-variants","display_name":"normal variants","score":0.5889999866485596},{"id":"https://openalex.org/keywords/histopathological-correlation","display_name":"histopathological correlation","score":0.5199999809265137}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8700424432754517},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.77359938621521},{"id":"https://openalex.org/C206111553","wikidata":"https://www.wikidata.org/wiki/Q3501532","display_name":"Echogenicity","level":3,"score":0.7367969155311584},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.7102794647216797},{"id":"https://openalex.org/C2776229224","wikidata":"https://www.wikidata.org/wiki/Q844903","display_name":"Trisomy","level":2,"score":0.546747624874115},{"id":"https://openalex.org/C2779672484","wikidata":"https://www.wikidata.org/wiki/Q529622","display_name":"Aneuploidy","level":4,"score":0.4801718294620514},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.47894197702407837},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.43520447611808777},{"id":"https://openalex.org/C2777274916","wikidata":"https://www.wikidata.org/wiki/Q1913658","display_name":"Papillary muscle","level":2,"score":0.42243483662605286},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.41458821296691895},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3554617464542389},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.20080256462097168},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.17315083742141724},{"id":"https://openalex.org/C529618451","wikidata":"https://www.wikidata.org/wiki/Q234904","display_name":"Ultrasonography","level":2,"score":0.1261393427848816},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.09677985310554504},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.05123290419578552},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002114","descriptor_name":"Calcinosis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002114","descriptor_name":"Calcinosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005315","descriptor_name":"Fetal Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005315","descriptor_name":"Fetal Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005318","descriptor_name":"Fetal Heart","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005318","descriptor_name":"Fetal Heart","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010210","descriptor_name":"Papillary Muscles","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D010210","descriptor_name":"Papillary Muscles","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016216","descriptor_name":"Ultrasonography, Prenatal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.7863/jum.1994.13.8.613","doi":"https://doi.org/10.7863/jum.1994.13.8.613","is_oa":false,"landing_page_url":"https://doi.org/10.7863/jum.1994.13.8.613","pdf_url":null,"source":{"id":"https://openalex.org/S111362775","display_name":"Journal of Ultrasound in Medicine","issn_l":"0278-4297","issn":["0278-4297","1550-9613"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Ultrasound in Medicine","raw_type":"journal-article"},{"id":"pmid:7933029","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7933029","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":5,"referenced_works":["https://openalex.org/W602617065","https://openalex.org/W1825819759","https://openalex.org/W2105376757","https://openalex.org/W2109344184","https://openalex.org/W2169732700"],"related_works":["https://openalex.org/W2043493789","https://openalex.org/W1974312960","https://openalex.org/W2079487552","https://openalex.org/W2099439118","https://openalex.org/W198416718","https://openalex.org/W2080066615","https://openalex.org/W2118421700","https://openalex.org/W1964963427","https://openalex.org/W2039530832","https://openalex.org/W2002832868"],"abstract_inverted_index":{"Echogenic":[0,81],"foci":[1,33,82],"within":[2,64,83],"the":[3,7,68,75,84,88,111],"left":[4,85,112],"ventricle":[5,86,113],"of":[6,15,31,74,87],"heart":[8,90],"have":[9,34],"been":[10],"found":[11],"in":[12,46,58,110],"a":[13,23,65,118],"minority":[14],"fetuses":[16,41,61,77],"and":[17,28],"generally":[18],"are":[19,98],"believed":[20],"to":[21,100],"be":[22,116],"normal":[24,119],"variant.":[25,120],"The":[26,52],"cause":[27],"exact":[29],"location":[30],"these":[32],"remained":[35],"speculative,":[36],"however.":[37],"We":[38],"identified":[39],"three":[40,60,76],"with":[42,105],"this":[43],"sonographic":[44],"finding":[45,56],"whom":[47],"pathologic":[48],"correlation":[49],"was":[50,62],"available.":[51],"only":[53],"consistent":[54],"histologic":[55],"present":[57],"all":[59],"mineralization":[63],"papillary":[66,92],"muscle;":[67],"chordae":[69],"tendineae":[70],"were":[71],"normal.":[72],"One":[73],"had":[78],"trisomy":[79],"21.":[80],"fetal":[89],"represent":[91],"muscle":[93],"mineralization.":[94],"Until":[95],"more":[96],"data":[97],"available":[99],"investigate":[101],"any":[102],"possible":[103],"association":[104],"aneuploidy,":[106],"an":[107],"echogenic":[108],"focus":[109],"should":[114],"still":[115],"considered":[117]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}