{"id":"https://openalex.org/W1950375378","doi":"https://doi.org/10.1186/1471-2407-6-175","title":"Effects of polymorphisms in ERCC1, ASE-1 and RAIon the risk of colorectal carcinomas and adenomas: a case control study","display_name":"Effects of polymorphisms in ERCC1, ASE-1 and RAIon the risk of colorectal carcinomas and adenomas: a case control study","publication_year":2006,"publication_date":"2006-07-03","ids":{"openalex":"https://openalex.org/W1950375378","doi":"https://doi.org/10.1186/1471-2407-6-175","mag":"1950375378","pmid":"https://pubmed.ncbi.nlm.nih.gov/16817948","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1533843"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2407-6-175","doi":"https://doi.org/10.1186/1471-2407-6-175","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2407-6-175","pdf_url":"https://bmccancer.biomedcentral.com/counter/pdf/10.1186/1471-2407-6-175","source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmccancer.biomedcentral.com/counter/pdf/10.1186/1471-2407-6-175","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002085848","display_name":"Camilla Furu Skjelbred","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117575","display_name":"Telemark Hospital","ror":"https://ror.org/02fafrk51","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I4210117575","https://openalex.org/I4210123979"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Camilla F Skjelbred","raw_affiliation_strings":["Department of Laboratory Medicine, Section of Medical Genetics, Telemark Hospital, N-3710 Skien, Norway. camilla-furu.skjelbred@sthf.no","Department of Laboratory Medicine, Section of Medical Genetics, Telemark Hospital, N-3710, Skien, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Section of Medical Genetics, Telemark Hospital, N-3710 Skien, Norway. camilla-furu.skjelbred@sthf.no","institution_ids":["https://openalex.org/I4210117575"]},{"raw_affiliation_string":"Department of Laboratory Medicine, Section of Medical Genetics, Telemark Hospital, N-3710, Skien, Norway","institution_ids":["https://openalex.org/I4210117575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066136448","display_name":"Mona S\u00e6b\u00f8","orcid":"https://orcid.org/0000-0003-3659-9118","observed_orcids":["https://orcid.org/0000-0003-3659-9118"]},"institutions":[{"id":"https://openalex.org/I4405285001","display_name":"Telemark University College","ror":"https://ror.org/04kh49447","country_code":"NO","type":"education","lineage":["https://openalex.org/I2801380234","https://openalex.org/I4405285001"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Mona S\u00e6b\u00f8","raw_affiliation_strings":["Telemark University College, Faculty of Arts and Sciences, Department of Environmental and Health Studies, Hallvard Eikas plass, N-3800, B\u00f8 i Telemark, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Telemark University College, Faculty of Arts and Sciences, Department of Environmental and Health Studies, Hallvard Eikas plass, N-3800, B\u00f8 i Telemark, Norway","institution_ids":["https://openalex.org/I4405285001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024788650","display_name":"Bj\u00f8rn Andersen Nex\u00f8","orcid":"https://orcid.org/0000-0003-3863-946X","observed_orcids":["https://orcid.org/0000-0003-3863-946X"]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Bj\u00f8rn A Nex\u00f8","raw_affiliation_strings":["Institute of Human Genetics, University of Aarhus, Aarhus, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Human Genetics, University of Aarhus, Aarhus, Denmark","institution_ids":["https://openalex.org/I204337017"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035288469","display_name":"H\u00e5kan Wallin","orcid":"https://orcid.org/0000-0001-7716-0166","observed_orcids":["https://orcid.org/0000-0001-7716-0166"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H\u00e5kan Wallin","raw_affiliation_strings":["National Institute of Occupational Health, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Occupational Health, Copenhagen, Denmark","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111456061","display_name":"Inger\u2010Lise Hansteen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117575","display_name":"Telemark Hospital","ror":"https://ror.org/02fafrk51","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I4210117575","https://openalex.org/I4210123979"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Inger-Lise Hansteen","raw_affiliation_strings":["Department of Laboratory Medicine, Section of Medical Genetics, Telemark Hospital, N-3710, Skien, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Section of Medical Genetics, Telemark Hospital, N-3710, Skien, Norway","institution_ids":["https://openalex.org/I4210117575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016513487","display_name":"Ulla Birgitte Vogel","orcid":"https://orcid.org/0000-0001-6807-1524","observed_orcids":["https://orcid.org/0000-0001-6807-1524"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ulla Vogel","raw_affiliation_strings":["National Institute of Occupational Health, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Occupational Health, Copenhagen, Denmark","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008647467","display_name":"Elin Hegland Kure","orcid":"https://orcid.org/0000-0002-5135-9916","observed_orcids":["https://orcid.org/0000-0002-5135-9916"]},"institutions":[{"id":"https://openalex.org/I1281400175","display_name":"Oslo University Hospital","ror":"https://ror.org/00j9c2840","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I1281400175"]},{"id":"https://openalex.org/I4405285001","display_name":"Telemark University College","ror":"https://ror.org/04kh49447","country_code":"NO","type":"education","lineage":["https://openalex.org/I2801380234","https://openalex.org/I4405285001"]}],"countries":["NO"],"is_corresponding":true,"raw_author_name":"Elin H Kure","raw_affiliation_strings":["Department of Pathology, Ullevaal University Hospital, Oslo, Norway","Telemark University College, Faculty of Arts and Sciences, Department of Environmental and Health Studies, Hallvard Eikas plass, N-3800, B\u00f8 i Telemark, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Ullevaal University Hospital, Oslo, Norway","institution_ids":["https://openalex.org/I1281400175"]},{"raw_affiliation_string":"Telemark University College, Faculty of Arts and Sciences, Department of Environmental and Health Studies, Hallvard Eikas plass, N-3800, B\u00f8 i Telemark, Norway","institution_ids":["https://openalex.org/I4405285001"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5008647467"],"corresponding_institution_ids":["https://openalex.org/I1281400175","https://openalex.org/I4405285001"],"apc_list":{"value":3390,"currency":"USD","value_usd":3390},"apc_paid":{"value":3390,"currency":"USD","value_usd":3390},"fwci":2.1694,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.87058126,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"6","issue":"1","first_page":"175","last_page":"175"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9580000042915344},{"id":"https://openalex.org/keywords/colorectal-adenoma","display_name":"colorectal adenoma","score":0.890999972820282},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9300000071525574},{"id":"https://openalex.org/keywords/ercc1","display_name":"ERCC1","score":0.9829999804496765},{"id":"https://openalex.org/keywords/rai","display_name":"RAI","score":0.9279999732971191},{"id":"https://openalex.org/keywords/haplotypes","display_name":"haplotypes","score":0.7649999856948853},{"id":"https://openalex.org/keywords/dna-repair-genes","display_name":"DNA repair genes","score":0.8399999737739563},{"id":"https://openalex.org/keywords/apoptosis-related-genes","display_name":"apoptosis-related genes","score":0.8989999890327454},{"id":"https://openalex.org/keywords/cancer-susceptibility","display_name":"cancer susceptibility","score":0.718999981880188},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7850000262260437},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.4429999887943268}],"concepts":[{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.6581836938858032},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6489481925964355},{"id":"https://openalex.org/C2776861080","wikidata":"https://www.wikidata.org/wiki/Q2825480","display_name":"Colorectal adenoma","level":4,"score":0.6422269344329834},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6055302619934082},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5851173400878906},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5661869645118713},{"id":"https://openalex.org/C146304588","wikidata":"https://www.wikidata.org/wiki/Q961652","display_name":"Case-control study","level":2,"score":0.4973345100879669},{"id":"https://openalex.org/C2777428134","wikidata":"https://www.wikidata.org/wiki/Q272741","display_name":"Adenoma","level":2,"score":0.43702980875968933},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.38167500495910645},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.28953683376312256}],"mesh":[{"descriptor_ui":"D000236","descriptor_name":"Adenoma","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D000236","descriptor_name":"Adenoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002888","descriptor_name":"Chromosomes, Human, Pair 19","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004720","descriptor_name":"Endonucleases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012318","descriptor_name":"RNA Polymerase I","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047908","descriptor_name":"Intracellular Signaling Peptides and Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":9,"locations":[{"id":"doi:10.1186/1471-2407-6-175","doi":"https://doi.org/10.1186/1471-2407-6-175","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2407-6-175","pdf_url":"https://bmccancer.biomedcentral.com/counter/pdf/10.1186/1471-2407-6-175","source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:338204","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1533843","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:16817948","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16817948","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC cancer","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1533843","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1533843/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:publications/73db3f00-c59c-11db-bee9-02004c4f4f50","doi":null,"is_oa":false,"landing_page_url":"https://pure.au.dk/portal/en/publications/73db3f00-c59c-11db-bee9-02004c4f4f50","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Skjelbred, C F, Saebo, M, Nex\u00f8, B A, Wallin, H, Hansteen, I-L, Vogel, U & Kure, E H 2006, 'Effects of polymorphisms in ERCC1, ASE-1 and RAI in the risk of colorectal carcinomas and adenomas: a case control study', B M C Cancer, vol. 6, pp. 175.","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:openarchive.usn.no:11250/2439249","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11250/2439249","pdf_url":"http://hdl.handle.net/11250/2439249","source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.824.7923","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.824.7923","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://teora.hit.no/bitstream/handle/2282/431/Effects_of_polymorphisms.pdf%3Bjsessionid%3DBCFD280B0DE00FBF5704DA0CEBC377BF?sequence%3D1","raw_type":"text"},{"id":"pmh:oai:brage.bibsys.no:11250/2437978","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11250/2437978","pdf_url":null,"source":{"id":"https://openalex.org/S4306400255","display_name":"BIBSYS Brage (BIBSYS (Norway))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I173212132","host_organization_name":"Vilnius University","host_organization_lineage":["https://openalex.org/I173212132"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal article"},{"id":"pmh:oai:doaj.org/article:55cbe642a4a447cc9476d33b2a747e52","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/55cbe642a4a447cc9476d33b2a747e52","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Cancer, Vol 6, Iss 1, p 175 (2006)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/1471-2407-6-175","doi":"https://doi.org/10.1186/1471-2407-6-175","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2407-6-175","pdf_url":"https://bmccancer.biomedcentral.com/counter/pdf/10.1186/1471-2407-6-175","source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9969000220298767,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320310758","display_name":"Kreftforeningen","ror":"https://ror.org/01925vb10"},{"id":"https://openalex.org/F4320311284","display_name":"EkstraStiftelsen Helse og Rehabilitering (Stiftelsen Dam)","ror":"https://ror.org/02esmmc86"},{"id":"https://openalex.org/F4320324107","display_name":"Ministeriet Sundhed Forebyggelse","ror":"https://ror.org/05kxbax75"},{"id":"https://openalex.org/F4320333059","display_name":"Nutrition Obesity Research Center, University of North Carolina","ror":"https://ror.org/02f0bym65"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1950375378.pdf","grobid_xml":"https://content.openalex.org/works/W1950375378.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1583476286","https://openalex.org/W1907220242","https://openalex.org/W1980297674","https://openalex.org/W1983520152","https://openalex.org/W2010562722","https://openalex.org/W2015649018","https://openalex.org/W2025544961","https://openalex.org/W2041574652","https://openalex.org/W2049699248","https://openalex.org/W2052484806","https://openalex.org/W2068289325","https://openalex.org/W2091723114","https://openalex.org/W2116298638","https://openalex.org/W2118094114","https://openalex.org/W2121245276","https://openalex.org/W2129715759","https://openalex.org/W2130503316","https://openalex.org/W2139743815","https://openalex.org/W2143611358","https://openalex.org/W2146108176","https://openalex.org/W2151807575","https://openalex.org/W2163376926","https://openalex.org/W2166182249","https://openalex.org/W2187539989"],"related_works":["https://openalex.org/W7096512694","https://openalex.org/W1969273279","https://openalex.org/W4404802806","https://openalex.org/W4402552963","https://openalex.org/W2028183708","https://openalex.org/W2040443313","https://openalex.org/W2106883076","https://openalex.org/W2079141438","https://openalex.org/W2617353295","https://openalex.org/W1987129109"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,143,174],"risk":[2,73,112,151,181,213,218,251,270],"of":[3,21,64,74,113,152,155,169,187,195,210,219,223,252,271],"sporadic":[4],"colorectal":[5,48,75,114,220,255,272],"cancer":[6,256,273],"is":[7,69],"mainly":[8],"associated":[9,70,147,249],"with":[10,71,148,250],"lifestyle":[11],"factors":[12,20],"and":[13,67,77,90,109,111,116,125,140,192,274],"may":[14,41,268],"be":[15],"modulated":[16],"by":[17,27,132],"several":[18],"genetic":[19],"low":[22],"penetrance.":[23],"Genetic":[24],"variants":[25],"represented":[26],"single":[28],"nucleotide":[29],"polymorphisms":[30,98,247],"in":[31,36,45,99,118,277],"genes":[32,63,106],"encoding":[33],"key":[34],"players":[35],"the":[37,58,95,100,105,211,233,245,265],"adenoma":[38,275],"carcinoma":[39],"sequence":[40],"contribute":[42],"to":[43,47,55,93,229],"variation":[44],"susceptibility":[46],"cancer.":[49],"In":[50],"this":[51],"study,":[52],"we":[53,260],"aimed":[54],"evaluate":[56],"whether":[57],"recently":[59],"identified":[60],"haplotype":[61,214],"encompassing":[62,104],"DNA":[65],"repair":[66],"apoptosis,":[68],"increased":[72,150,217],"adenomas":[76,89,115,185,253],"carcinomas.":[78],"METHODS:":[79],"We":[80,240],"used":[81],"a":[82,119,178],"case-control":[83],"study":[84],"design":[85],"(156":[86],"carcinomas,":[87],"981":[88],"399":[91],"controls)":[92],"test":[94],"association":[96],"between":[97],"chromosomal":[101,266],"region":[102,267],"19q13.2-3,":[103],"ERCC1,":[107],"ASE-1":[108,144],"RAI,":[110],"carcinomas":[117,193],"Norwegian":[120],"cohort.":[121],"Odds":[122],"ratio":[123],"(OR)":[124],"95%":[126,189,197],"confidence":[127],"interval":[128],"(CI)":[129],"were":[130,207,248],"estimated":[131],"binary":[133],"logistic":[134],"regression":[135],"model":[136],"adjusting":[137],"for":[138,183],"age":[139],"gender.":[141],"RESULTS:":[142],"polymorphism":[145,176],"was":[146,163,235],"an":[149,216],"adenomas,":[153],"OR":[154,168,222],"1.39":[156],"(95%":[157,171,225],"CI":[158,172,190,198,226],"1.06-1.81),":[159],"which":[160],"upon":[161],"stratification":[162],"apparent":[164],"among":[165,200,257],"women":[166],"only,":[167],"1.66":[170],"1.15-2.39).":[173],"RAI":[175],"showed":[177],"trend":[179],"towards":[180],"reduction":[182],"both":[184],"(OR":[186,194],"0.70,":[188],"0.49-1.01)":[191],"0.49,":[196],"0.21-1.13)":[199],"women,":[201],"although":[202,232],"not":[203,236],"significant.":[204,238],"Women":[205],"who":[206],"homozygous":[208],"carriers":[209],"high":[212],"had":[215],"cancer,":[221],"2.19":[224],"0.95-5.04)":[227],"compared":[228],"all":[230],"non-carriers":[231],"estimate":[234],"statistically":[237],"CONCLUSION:":[239],"found":[241,261],"no":[242],"evidence":[243],"that":[244,264],"studied":[246],"or":[254],"men,":[258],"but":[259],"weak":[262],"indications":[263],"influence":[269],"development":[276],"women.":[278]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}