{"id":"https://openalex.org/W1948259362","doi":"https://doi.org/10.1002/psc.2772","title":"Curvature sensing MARCKS\u2010ED peptides bind to membranes in a stereo\u2010independent manner","display_name":"Curvature sensing MARCKS\u2010ED peptides bind to membranes in a stereo\u2010independent manner","publication_year":2015,"publication_date":"2015-04-08","ids":{"openalex":"https://openalex.org/W1948259362","doi":"https://doi.org/10.1002/psc.2772","mag":"1948259362","pmid":"https://pubmed.ncbi.nlm.nih.gov/25851418","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4480065"},"language":"en","primary_location":{"id":"doi:10.1002/psc.2772","doi":"https://doi.org/10.1002/psc.2772","is_oa":false,"landing_page_url":"https://doi.org/10.1002/psc.2772","pdf_url":null,"source":{"id":"https://openalex.org/S184443419","display_name":"Journal of Peptide Science","issn_l":"1075-2617","issn":["1075-2617","1099-1387"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Peptide Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4480065","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101675160","display_name":"Lei Yan","orcid":"https://orcid.org/0000-0001-5259-3379","observed_orcids":["https://orcid.org/0000-0001-5259-3379"]},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Yan","raw_affiliation_strings":["Center of Basic Molecular Science, Department of Chemistry, Tsinghua University, Beijing, 100082, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Basic Molecular Science, Department of Chemistry, Tsinghua University, Beijing, 100082, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008269794","display_name":"Armando Jerome de Jesus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]},{"id":"https://openalex.org/I2802236040","display_name":"University of Colorado System","ror":"https://ror.org/00jc20583","country_code":"US","type":"education","lineage":["https://openalex.org/I2802236040"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Armando Jerome de Jesus","raw_affiliation_strings":["Department of Chemistry and Biochemistry, the BioFrontiers Institute University of Colorado Boulder Boulder CO 80309\u20100596 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, the BioFrontiers Institute University of Colorado Boulder Boulder CO 80309\u20100596 USA","institution_ids":["https://openalex.org/I188538660","https://openalex.org/I2802236040"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ryo Tamura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]},{"id":"https://openalex.org/I2802236040","display_name":"University of Colorado System","ror":"https://ror.org/00jc20583","country_code":"US","type":"education","lineage":["https://openalex.org/I2802236040"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ryo Tamura","raw_affiliation_strings":["Department of Chemistry and Biochemistry, the BioFrontiers Institute University of Colorado Boulder Boulder CO 80309\u20100596 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, the BioFrontiers Institute University of Colorado Boulder Boulder CO 80309\u20100596 USA","institution_ids":["https://openalex.org/I188538660","https://openalex.org/I2802236040"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053547103","display_name":"Victoria Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]},{"id":"https://openalex.org/I2802236040","display_name":"University of Colorado System","ror":"https://ror.org/00jc20583","country_code":"US","type":"education","lineage":["https://openalex.org/I2802236040"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Victoria Li","raw_affiliation_strings":["Department of Chemistry and Biochemistry, the BioFrontiers Institute University of Colorado Boulder Boulder CO 80309\u20100596 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, the BioFrontiers Institute University of Colorado Boulder Boulder CO 80309\u20100596 USA","institution_ids":["https://openalex.org/I188538660","https://openalex.org/I2802236040"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058057676","display_name":"Kui Cheng","orcid":"https://orcid.org/0000-0002-4136-2070","observed_orcids":["https://orcid.org/0000-0002-4136-2070"]},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kui Cheng","raw_affiliation_strings":["Center of Basic Molecular Science, Department of Chemistry, Tsinghua University, Beijing, 100082, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Basic Molecular Science, Department of Chemistry, Tsinghua University, Beijing, 100082, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025581121","display_name":"Hang Hubert Yin","orcid":"https://orcid.org/0000-0002-9762-4818","observed_orcids":["https://orcid.org/0000-0002-9762-4818"]},"institutions":[{"id":"https://openalex.org/I188538660","display_name":"University of Colorado Boulder","ror":"https://ror.org/02ttsq026","country_code":"US","type":"education","lineage":["https://openalex.org/I188538660"]},{"id":"https://openalex.org/I2802236040","display_name":"University of Colorado System","ror":"https://ror.org/00jc20583","country_code":"US","type":"education","lineage":["https://openalex.org/I2802236040"]},{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Hang Yin","raw_affiliation_strings":["Center of Basic Molecular Science, Department of Chemistry Tsinghua University Beijing 100082 China","Department of Chemistry and Biochemistry, the BioFrontiers Institute University of Colorado Boulder Boulder CO 80309\u20100596 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Basic Molecular Science, Department of Chemistry Tsinghua University Beijing 100082 China","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, the BioFrontiers Institute University of Colorado Boulder Boulder CO 80309\u20100596 USA","institution_ids":["https://openalex.org/I188538660","https://openalex.org/I2802236040"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5025581121"],"corresponding_institution_ids":["https://openalex.org/I188538660","https://openalex.org/I2802236040","https://openalex.org/I99065089"],"apc_list":{"value":4030,"currency":"USD","value_usd":4030},"apc_paid":null,"fwci":0.6574,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.65455283,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"21","issue":"7","first_page":"577","last_page":"585"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/membrane-curvature-sensing","display_name":"membrane curvature sensing","score":0.9559999704360962},{"id":"https://openalex.org/keywords/d-amino-acid-peptides","display_name":"D-amino acid peptides","score":0.7870000004768372},{"id":"https://openalex.org/keywords/peptide-membrane-binding","display_name":"peptide-membrane binding","score":0.7829999923706055},{"id":"https://openalex.org/keywords/boat-conformation","display_name":"boat conformation","score":0.6499999761581421},{"id":"https://openalex.org/keywords/circular-dichroism","display_name":"circular dichroism","score":0.8379999995231628},{"id":"https://openalex.org/keywords/fluorescence-enhancement","display_name":"fluorescence enhancement","score":0.6990000009536743},{"id":"https://openalex.org/keywords/marcks","display_name":"MARCKS","score":0.8489999771118164}],"concepts":[{"id":"https://openalex.org/C2780780085","wikidata":"https://www.wikidata.org/wiki/Q18028763","display_name":"MARCKS","level":4,"score":0.9761435985565186},{"id":"https://openalex.org/C2777278457","wikidata":"https://www.wikidata.org/wiki/Q6815124","display_name":"Membrane curvature","level":4,"score":0.7527444362640381},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.5980639457702637},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.564393937587738},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5287786722183228},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.526644229888916},{"id":"https://openalex.org/C77207865","wikidata":"https://www.wikidata.org/wiki/Q25794","display_name":"Myristoylation","level":3,"score":0.5120971202850342},{"id":"https://openalex.org/C195065555","wikidata":"https://www.wikidata.org/wiki/Q214881","display_name":"Curvature","level":2,"score":0.4839347004890442},{"id":"https://openalex.org/C39944091","wikidata":"https://www.wikidata.org/wiki/Q423279","display_name":"Lipid bilayer","level":3,"score":0.3344970941543579},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2916083335876465},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.27385443449020386},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.09246665239334106},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000076250","descriptor_name":"Myristoylated Alanine-Rich C Kinase Substrate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001572","descriptor_name":"Benzofurans","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008051","descriptor_name":"Lipid Bilayers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D010718","descriptor_name":"Phosphatidylserines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013050","descriptor_name":"Spectrometry, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013237","descriptor_name":"Stereoisomerism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047908","descriptor_name":"Intracellular Signaling Peptides and Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/psc.2772","doi":"https://doi.org/10.1002/psc.2772","is_oa":false,"landing_page_url":"https://doi.org/10.1002/psc.2772","pdf_url":null,"source":{"id":"https://openalex.org/S184443419","display_name":"Journal of Peptide Science","issn_l":"1075-2617","issn":["1075-2617","1099-1387"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Peptide Science","raw_type":"journal-article"},{"id":"pmid:25851418","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25851418","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of peptide science : an official publication of the European Peptide Society","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4480065","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4480065","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Pept Sci","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4480065","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4480065","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Pept Sci","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5700174641","display_name":"Exogenous Chemical Probes of TLR-Mediated Neuroinflammation","funder_award_id":"R01GM101279","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6164080798","display_name":"Dissecting Cell Signaling Mediated by Protein-Protein Interactions in Membranes","funder_award_id":"R01GM103843","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7935468820","display_name":"CAREER: Promoting Chemical Biology Education and Research: Understanding Molecular Recognition in Membranes","funder_award_id":"0954819","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":78,"referenced_works":["https://openalex.org/W1949471596","https://openalex.org/W1968823199","https://openalex.org/W1970542943","https://openalex.org/W1973036661","https://openalex.org/W1976499671","https://openalex.org/W1978724459","https://openalex.org/W1982196959","https://openalex.org/W1984250381","https://openalex.org/W1986529651","https://openalex.org/W1986582116","https://openalex.org/W1987131886","https://openalex.org/W1987409881","https://openalex.org/W1989479561","https://openalex.org/W1989855778","https://openalex.org/W1991622669","https://openalex.org/W1991794210","https://openalex.org/W1995112887","https://openalex.org/W1996868880","https://openalex.org/W1997433203","https://openalex.org/W2001551567","https://openalex.org/W2007285240","https://openalex.org/W2007483105","https://openalex.org/W2007767060","https://openalex.org/W2014069822","https://openalex.org/W2014393577","https://openalex.org/W2021858530","https://openalex.org/W2022964566","https://openalex.org/W2027189612","https://openalex.org/W2027408247","https://openalex.org/W2028622306","https://openalex.org/W2030143885","https://openalex.org/W2032240634","https://openalex.org/W2035844407","https://openalex.org/W2038758364","https://openalex.org/W2046189032","https://openalex.org/W2050333027","https://openalex.org/W2054750950","https://openalex.org/W2055154757","https://openalex.org/W2062940933","https://openalex.org/W2066414494","https://openalex.org/W2069774245","https://openalex.org/W2071105928","https://openalex.org/W2071877471","https://openalex.org/W2072167784","https://openalex.org/W2074099524","https://openalex.org/W2074156609","https://openalex.org/W2074999590","https://openalex.org/W2083212567","https://openalex.org/W2086046956","https://openalex.org/W2088877201","https://openalex.org/W2092822354","https://openalex.org/W2100869615","https://openalex.org/W2104571730","https://openalex.org/W2106140689","https://openalex.org/W2106333373","https://openalex.org/W2108586733","https://openalex.org/W2109744052","https://openalex.org/W2111188739","https://openalex.org/W2114628856","https://openalex.org/W2119253842","https://openalex.org/W2121966104","https://openalex.org/W2124336651","https://openalex.org/W2127234404","https://openalex.org/W2131973218","https://openalex.org/W2135752614","https://openalex.org/W2141064727","https://openalex.org/W2142755954","https://openalex.org/W2143580680","https://openalex.org/W2152270594","https://openalex.org/W2156851380","https://openalex.org/W2162166182","https://openalex.org/W2168135619","https://openalex.org/W2168269595","https://openalex.org/W2168326351","https://openalex.org/W2169491358","https://openalex.org/W2170114979","https://openalex.org/W2326873831","https://openalex.org/W4243226078"],"related_works":["https://openalex.org/W2007285240","https://openalex.org/W2001551567","https://openalex.org/W2352886595","https://openalex.org/W4252384679","https://openalex.org/W6929565280","https://openalex.org/W1989326050","https://openalex.org/W6906789746","https://openalex.org/W2960556564","https://openalex.org/W2244940387","https://openalex.org/W1968823199"],"abstract_inverted_index":{"Membrane":[0],"curvature":[1,18,100,189,201],"and":[2,13,26,78,101,134,147,156,168],"lipid":[3,102],"composition":[4],"plays":[5],"a":[6,99,117,194],"critical":[7],"role":[8],"in":[9,15,153],"interchanging":[10],"of":[11,45,127,145,158,165,184],"matter":[12],"energy":[14],"cells.":[16],"Peptide":[17],"sensors":[19],"are":[20,149],"known":[21],"to":[22,56,116,122,174,181,197],"activate":[23],"signaling":[24],"pathways":[25],"promote":[27],"molecular":[28,106],"transport":[29],"across":[30],"cell":[31],"membranes.":[32,176],"Recently,":[33],"the":[34,42,46,68,91,123,154],"25-mer":[35],"MARCKS-ED":[36,186],"peptide,":[37],"which":[38],"is":[39],"derived":[40],"from":[41,114],"effector":[43],"domain":[44],"myristoylated":[47],"alanine-rich":[48],"C":[49],"kinase":[50],"substrate":[51],"protein,":[52],"has":[53,90],"been":[54],"reported":[55],"selectively":[57],"recognize":[58],"highly":[59],"curved":[60,175],"membrane":[61,188,200],"surfaces.":[62],"Our":[63,177],"previous":[64],"studies":[65,178],"indicated":[66],"that":[67,83,110],"naturally":[69],"occurring":[70],"L-MARCKS-ED":[71,135,148,170],"peptide":[72],"could":[73],"simultaneously":[74],"detect":[75],"both":[76,152],"phosphatidylserine":[77],"curvature.":[79],"Here,":[80],"we":[81],"demonstrate":[82],"D-MARCKS-ED,":[84],"composed":[85],"by":[86],"unnatural":[87],"D-amino":[88],"acids,":[89],"same":[92],"activities":[93],"as":[94,98,190,192],"its":[95],"enantiomer,":[96],"L-MARCKS-ED,":[97],"sensor.":[103],"An":[104],"atomistic":[105],"dynamics":[107],"simulation":[108],"suggests":[109],"D-MARCKS-ED":[111],"may":[112,179],"change":[113],"linear":[115],"boat":[118],"conformation":[119],"upon":[120],"binding":[121,139,173],"membrane.":[124],"Comparable":[125],"enhancement":[126],"fluorescence":[128],"intensity":[129],"was":[130],"observed":[131],"between":[132],"D-":[133,146,167],"peptides,":[136],"indicating":[137],"similar":[138,163],"affinities.":[140],"Meanwhile,":[141],"circular":[142],"dichroism":[143],"spectra":[144],"almost":[150],"symmetrical":[151],"presence":[155],"absence":[157],"liposomes.":[159],"These":[160],"results":[161],"suggest":[162],"behavior":[164],"artificial":[166],"natural":[169],"peptides":[171],"when":[172],"contribute":[180],"further":[182],"understanding":[183],"how":[185],"senses":[187],"well":[191],"provide":[193],"new":[195],"direction":[196],"develop":[198],"novel":[199],"probes.":[202]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}