{"id":"https://openalex.org/W194753855","doi":"https://doi.org/10.1177/002203459207100s18","title":"Importance of Model Parameters in the Assessment of Intra-oral Remineralization","display_name":"Importance of Model Parameters in the Assessment of Intra-oral Remineralization","publication_year":1992,"publication_date":"1992-04-01","ids":{"openalex":"https://openalex.org/W194753855","doi":"https://doi.org/10.1177/002203459207100s18","mag":"194753855","pmid":"https://pubmed.ncbi.nlm.nih.gov/1592979"},"language":"en","primary_location":{"id":"doi:10.1177/002203459207100s18","doi":"https://doi.org/10.1177/002203459207100s18","is_oa":false,"landing_page_url":"https://doi.org/10.1177/002203459207100s18","pdf_url":null,"source":{"id":"https://openalex.org/S62865007","display_name":"Journal of Dental Research","issn_l":"0022-0345","issn":["0022-0345","1544-0591"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dental Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110134976","display_name":"Jacob M. ten Cate","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2898155008","display_name":"Academic Center for Dentistry Amsterdam","ror":"https://ror.org/04x5wnb75","country_code":"NL","type":"education","lineage":["https://openalex.org/I2898155008"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J.M. Ten Cate","raw_affiliation_strings":["Department of Cariology and Endodontology, Academic Centre for Dentistry Amsterdam, Louwesweg 1, 1066 EA Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cariology and Endodontology, Academic Centre for Dentistry Amsterdam, Louwesweg 1, 1066 EA Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2898155008"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073512751","display_name":"Y.M. Van De Plassche-Simons","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2898155008","display_name":"Academic Center for Dentistry Amsterdam","ror":"https://ror.org/04x5wnb75","country_code":"NL","type":"education","lineage":["https://openalex.org/I2898155008"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Y.M. Van De Plassche-Simons","raw_affiliation_strings":["Department of Cariology and Endodontology, Academic Centre for Dentistry, Amsterdam, Louwesweg 1, 1066 EA Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cariology and Endodontology, Academic Centre for Dentistry, Amsterdam, Louwesweg 1, 1066 EA Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2898155008"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113691027","display_name":"Augustinus J. P. van Strijp","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2898155008","display_name":"Academic Center for Dentistry Amsterdam","ror":"https://ror.org/04x5wnb75","country_code":"NL","type":"education","lineage":["https://openalex.org/I2898155008"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"A.J.P. Van Strijp","raw_affiliation_strings":["Department of Cariology and Endodontology, Academic Centre for Dentistry, Amsterdam, Louwesweg 1, 1066 EA Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cariology and Endodontology, Academic Centre for Dentistry, Amsterdam, Louwesweg 1, 1066 EA Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2898155008"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2898155008"],"apc_list":{"value":4400,"currency":"USD","value_usd":4400},"apc_paid":null,"fwci":3.9083,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.91366642,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"71","issue":"3_suppl","first_page":"879","last_page":"883"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11958","display_name":"Dental Erosion and Treatment","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/3505","display_name":"Orthodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dental-caries-prevention","display_name":"dental caries prevention","score":0.6579999923706055},{"id":"https://openalex.org/keywords/model-parameters","display_name":"model parameters","score":0.6610000133514404},{"id":"https://openalex.org/keywords/dental-plaque-accumulation","display_name":"plaque accumulation","score":0.7990000247955322},{"id":"https://openalex.org/keywords/fluoride-uptake","display_name":"fluoride uptake","score":0.7179999947547913},{"id":"https://openalex.org/keywords/mineral-absorption","display_name":"mineral absorption","score":0.7260000109672546},{"id":"https://openalex.org/keywords/experimental-design","display_name":"experimental design","score":0.7910000085830688}],"concepts":[{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.7017226219177246},{"id":"https://openalex.org/C156887251","wikidata":"https://www.wikidata.org/wiki/Q2386424","display_name":"Enamel paint","level":2,"score":0.689574122428894},{"id":"https://openalex.org/C2986629439","wikidata":"https://www.wikidata.org/wiki/Q9635","display_name":"Oral cavity","level":2,"score":0.6058575510978699},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.43993932008743286},{"id":"https://openalex.org/C112758219","wikidata":"https://www.wikidata.org/wiki/Q16038819","display_name":"Duration (music)","level":2,"score":0.4299226999282837},{"id":"https://openalex.org/C65409693","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Statistical significance","level":2,"score":0.4135664403438568},{"id":"https://openalex.org/C2777267654","wikidata":"https://www.wikidata.org/wiki/Q3519023","display_name":"Test (biology)","level":2,"score":0.41016387939453125},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.3686884641647339},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3334222435951233},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3267582058906555},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1301036775112152},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12279784679412842},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1011945903301239},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003731","descriptor_name":"Dental Caries","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014089","descriptor_name":"Tooth Remineralization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1177/002203459207100s18","doi":"https://doi.org/10.1177/002203459207100s18","is_oa":false,"landing_page_url":"https://doi.org/10.1177/002203459207100s18","pdf_url":null,"source":{"id":"https://openalex.org/S62865007","display_name":"Journal of Dental Research","issn_l":"0022-0345","issn":["0022-0345","1544-0591"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dental Research","raw_type":"journal-article"},{"id":"pmid:1592979","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1592979","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of dental research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W130693375","https://openalex.org/W199382352","https://openalex.org/W344499898","https://openalex.org/W1978945040","https://openalex.org/W1992423657","https://openalex.org/W1995326615","https://openalex.org/W2009000855","https://openalex.org/W2009132920","https://openalex.org/W2011209897","https://openalex.org/W2019708461","https://openalex.org/W2024397369","https://openalex.org/W2024801916","https://openalex.org/W2028593656","https://openalex.org/W2033404205","https://openalex.org/W2035841257","https://openalex.org/W2045238015","https://openalex.org/W2048202344","https://openalex.org/W2054148468","https://openalex.org/W2059534600","https://openalex.org/W2068786782","https://openalex.org/W2074537729","https://openalex.org/W2075221438","https://openalex.org/W2076885760","https://openalex.org/W2077739955","https://openalex.org/W2080974325","https://openalex.org/W2084153105","https://openalex.org/W2092340129","https://openalex.org/W2118844657","https://openalex.org/W2121480750","https://openalex.org/W2144872059","https://openalex.org/W2148383983","https://openalex.org/W2163160504","https://openalex.org/W2397222548","https://openalex.org/W2404128340","https://openalex.org/W2404757867","https://openalex.org/W2411981403"],"related_works":["https://openalex.org/W313460121","https://openalex.org/W1911905659","https://openalex.org/W117017466","https://openalex.org/W170109898","https://openalex.org/W1819018378","https://openalex.org/W197183891","https://openalex.org/W2153392694","https://openalex.org/W3664312","https://openalex.org/W4249973273","https://openalex.org/W95854813"],"abstract_inverted_index":{"Since":[0],"the":[1,4,16,38,44,60,63,69,76,85,98,109,116,119,122,134,144,159,163,178,181],"introduction":[2],"of":[3,43,47,62,71,87,92,100,118,124,146,172,177,180],"Intra-oral":[5],"Cariogenicity":[6],"Test":[7],"by":[8,156],"Koulourides":[9],"et":[10],"al.":[11],"(1974),":[12],"many":[13,64],"groups":[14],"around":[15],"world":[17],"have":[18],"been":[19,56],"developing":[20],"and":[21,142],"using":[22],"intra-oral":[23],"models":[24],"to":[25,33,58,105,111,130,168],"test":[26],"new":[27],"caries-preventive":[28],"products,":[29],"as":[30,32],"well":[31],"study":[34],"physiological":[35],"processes":[36],"in":[37,175],"oral":[39],"cavity.":[40],"In":[41],"spite":[42],"large":[45],"numbers":[46],"papers":[48],"reporting":[49],"these":[50,72,169],"methods,":[51],"very":[52],"little":[53],"research":[54],"has":[55],"done":[57],"determine":[59],"importance":[61,174],"variable":[65],"parameters":[66,170],"which":[67],"influence":[68],"performance":[70],"models.":[73],"Among":[74],"these,":[75],"following":[77],"can":[78],"be":[79,131],"identified:":[80],"(a)":[81],"panelist":[82],"criteria,":[83],"(b)":[84],"use":[86,99],"sound":[88],"vs.":[89],"pre-demineralized":[90],"enamel":[91],"human":[93],"or":[94,102,149],"bovine":[95],"origin,":[96],"(c)":[97],"gauze":[101],"a":[103],"recess":[104],"accumulate":[106],"plaque,":[107],"(d)":[108],"method":[110],"create":[112],"incipient":[113],"lesions,":[114],"(e)":[115],"duration":[117],"experiment,":[120],"(f)":[121],"number":[123],"panelists":[125],"required":[126],"for":[127,137],"statistical":[128],"significance":[129],"obtained,":[132],"(g)":[133],"assessment":[135],"techniques":[136],"mineral":[138],"and/or":[139],"fluoride":[140],"uptake/loss,":[141],"(h)":[143],"choice":[145],"contralateral,":[147],"'cross-over',":[148],"'monadic'":[150],"experimental":[151],"designs.":[152],"Our":[153],"results,":[154],"supported":[155],"data":[157],"from":[158],"literature,":[160],"indicate":[161],"that":[162],"choices":[164],"made":[165],"with":[166],"respect":[167],"are":[171],"paramount":[173],"determination":[176],"outcome":[179],"respective":[182],"study.":[183]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}