{"id":"https://openalex.org/W194006948","doi":null,"title":"BEYOND PEROXISOME: ABCD2 MODIFIES PPAR\u03b1 SIGNALING AND IDENTIFIES A SUBCLASS OF PEROXISOMES IN MOUSE ADIPOSE TISSUE","display_name":"BEYOND PEROXISOME: ABCD2 MODIFIES PPAR\u03b1 SIGNALING AND IDENTIFIES A SUBCLASS OF PEROXISOMES IN MOUSE ADIPOSE TISSUE","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W194006948","mag":"194006948"},"language":"en","primary_location":{"id":"pmh:oai:uknowledge.uky.edu:pharmacy_etds-1038","doi":null,"is_oa":true,"landing_page_url":"https://uknowledge.uky.edu/pharmacy_etds/41","pdf_url":"https://uknowledge.uky.edu/pharmacy_etds/41","source":{"id":"https://openalex.org/S4306402623","display_name":"UKnowledge (University of Kentucky)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I143302722","host_organization_name":"University of Kentucky","host_organization_lineage":["https://openalex.org/I143302722"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Theses and Dissertations--Pharmacy","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://uknowledge.uky.edu/pharmacy_etds/41","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100450538","display_name":"Xiaoxi Liu","orcid":"https://orcid.org/0000-0002-1933-8613","observed_orcids":["https://orcid.org/0000-0002-1933-8613","https://orcid.org/0009-0001-2614-7356"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Xiaoxi Liu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1933-8613","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5100450538"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00747824,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abcd2","display_name":"ABCD2","score":0.9950000047683716},{"id":"https://openalex.org/keywords/peroxisomes","display_name":"peroxisomes","score":0.7110000252723694},{"id":"https://openalex.org/keywords/microperoxisomes","display_name":"microperoxisomes","score":0.9190000295639038},{"id":"https://openalex.org/keywords/pparalpha-signaling","display_name":"PPAR\u03b1 signaling","score":0.9819999933242798},{"id":"https://openalex.org/keywords/fenofibrate","display_name":"fenofibrate","score":0.9779999852180481},{"id":"https://openalex.org/keywords/adipose-tissue","display_name":"adipose tissue","score":0.7820000052452087},{"id":"https://openalex.org/keywords/3t3-l1-adipocytes","display_name":"3T3-L1 adipocytes","score":0.8500000238418579},{"id":"https://openalex.org/keywords/diet-induced-obesity","display_name":"diet-induced obesity","score":0.9670000076293945},{"id":"https://openalex.org/keywords/hypertriglyceridemia","display_name":"hypertriglyceridemia","score":0.9909999966621399},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pex19","display_name":"PEX19","score":0.8840000033378601},{"id":"https://openalex.org/keywords/mitochondrial-association","display_name":"mitochondrial association","score":0.597000002861023},{"id":"https://openalex.org/keywords/endoplasmic-reticulum","display_name":"endoplasmic reticulum","score":0.8889999985694885},{"id":"https://openalex.org/keywords/subcellular-localization","display_name":"subcellular localization","score":0.6110000014305115}],"concepts":[{"id":"https://openalex.org/C127078168","wikidata":"https://www.wikidata.org/wiki/Q138639","display_name":"Peroxisome","level":3,"score":0.7261272072792053},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.7180144786834717},{"id":"https://openalex.org/C2776933373","wikidata":"https://www.wikidata.org/wiki/Q424744","display_name":"Fibrate","level":3,"score":0.6728755831718445},{"id":"https://openalex.org/C2778110834","wikidata":"https://www.wikidata.org/wiki/Q419724","display_name":"Fenofibrate","level":2,"score":0.6271605491638184},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5788869261741638},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5598839521408081},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4883589446544647},{"id":"https://openalex.org/C2776919658","wikidata":"https://www.wikidata.org/wiki/Q1467339","display_name":"Hypertriglyceridemia","level":4,"score":0.4633972942829132},{"id":"https://openalex.org/C44353895","wikidata":"https://www.wikidata.org/wiki/Q6556772","display_name":"Lipotoxicity","level":4,"score":0.4535568058490753},{"id":"https://openalex.org/C187345961","wikidata":"https://www.wikidata.org/wiki/Q419629","display_name":"Peroxisome proliferator-activated receptor","level":3,"score":0.45103156566619873},{"id":"https://openalex.org/C2777150068","wikidata":"https://www.wikidata.org/wiki/Q366964","display_name":"Adrenoleukodystrophy","level":4,"score":0.42790114879608154},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.27436864376068115},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.2604653239250183},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1795158088207245},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.1584976613521576},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.13017961382865906},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.06884041428565979}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:uknowledge.uky.edu:pharmacy_etds-1038","doi":null,"is_oa":true,"landing_page_url":"https://uknowledge.uky.edu/pharmacy_etds/41","pdf_url":"https://uknowledge.uky.edu/pharmacy_etds/41","source":{"id":"https://openalex.org/S4306402623","display_name":"UKnowledge (University of Kentucky)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I143302722","host_organization_name":"University of Kentucky","host_organization_lineage":["https://openalex.org/I143302722"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Theses and Dissertations--Pharmacy","raw_type":"text"},{"id":"mag:194006948","doi":null,"is_oa":false,"landing_page_url":"https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1038&context=pharmacy_etds","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:uknowledge.uky.edu:pharmacy_etds-1038","doi":null,"is_oa":true,"landing_page_url":"https://uknowledge.uky.edu/pharmacy_etds/41","pdf_url":"https://uknowledge.uky.edu/pharmacy_etds/41","source":{"id":"https://openalex.org/S4306402623","display_name":"UKnowledge (University of Kentucky)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I143302722","host_organization_name":"University of Kentucky","host_organization_lineage":["https://openalex.org/I143302722"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Theses and Dissertations--Pharmacy","raw_type":"text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W194006948.pdf","grobid_xml":"https://content.openalex.org/works/W194006948.grobid-xml"},"referenced_works_count":292,"referenced_works":["https://openalex.org/W30521292","https://openalex.org/W108510859","https://openalex.org/W121808767","https://openalex.org/W166610720","https://openalex.org/W288715965","https://openalex.org/W1499068934","https://openalex.org/W1533335653","https://openalex.org/W1544291394","https://openalex.org/W1545873547","https://openalex.org/W1546952499","https://openalex.org/W1588499193","https://openalex.org/W1596505093","https://openalex.org/W1608005125","https://openalex.org/W1671834350","https://openalex.org/W1672804368","https://openalex.org/W1675830194","https://openalex.org/W1786851531","https://openalex.org/W1827278273","https://openalex.org/W1843523988","https://openalex.org/W1854481398","https://openalex.org/W1870589536","https://openalex.org/W1961916049","https://openalex.org/W1963739832","https://openalex.org/W1963990984","https://openalex.org/W1964049730","https://openalex.org/W1964865129","https://openalex.org/W1966355534","https://openalex.org/W1967304387","https://openalex.org/W1968251331","https://openalex.org/W1968665346","https://openalex.org/W1970316586","https://openalex.org/W1971912406","https://openalex.org/W1972248992","https://openalex.org/W1972589545","https://openalex.org/W1974212760","https://openalex.org/W1975962309","https://openalex.org/W1977868067","https://openalex.org/W1977949786","https://openalex.org/W1978125779","https://openalex.org/W1978368157","https://openalex.org/W1979181144","https://openalex.org/W1979761686","https://openalex.org/W1980049085","https://openalex.org/W1983498453","https://openalex.org/W1985735647","https://openalex.org/W1986449189","https://openalex.org/W1986865985","https://openalex.org/W1987601583","https://openalex.org/W1988723645","https://openalex.org/W1988870963","https://openalex.org/W1989016558","https://openalex.org/W1991334358","https://openalex.org/W1991932125","https://openalex.org/W1998434356","https://openalex.org/W1998699321","https://openalex.org/W2000135935","https://openalex.org/W2000797253","https://openalex.org/W2001657480","https://openalex.org/W2002285852","https://openalex.org/W2003380115","https://openalex.org/W2006688731","https://openalex.org/W2007886762","https://openalex.org/W2008688211","https://openalex.org/W2008962463","https://openalex.org/W2009917506","https://openalex.org/W2011983428","https://openalex.org/W2012693121","https://openalex.org/W2012898950","https://openalex.org/W2013874605","https://openalex.org/W2014259643","https://openalex.org/W2015708524","https://openalex.org/W2015764278","https://openalex.org/W2016070194","https://openalex.org/W2020892886","https://openalex.org/W2021758696","https://openalex.org/W2022048961","https://openalex.org/W2022174018","https://openalex.org/W2024217191","https://openalex.org/W2024526192","https://openalex.org/W2024596503","https://openalex.org/W2025104020","https://openalex.org/W2026306987","https://openalex.org/W2029957148","https://openalex.org/W2032101761","https://openalex.org/W2032849264","https://openalex.org/W2033862533","https://openalex.org/W2033912719","https://openalex.org/W2035216298","https://openalex.org/W2035232572","https://openalex.org/W2036290445","https://openalex.org/W2036413464","https://openalex.org/W2037167329","https://openalex.org/W2038120135","https://openalex.org/W2039231850","https://openalex.org/W2039333506","https://openalex.org/W2042618169","https://openalex.org/W2043106623","https://openalex.org/W2043763182","https://openalex.org/W2046268728","https://openalex.org/W2046378557","https://openalex.org/W2046759275","https://openalex.org/W2047982128","https://openalex.org/W2048577023","https://openalex.org/W2050895281","https://openalex.org/W2051051060","https://openalex.org/W2051287539","https://openalex.org/W2051698507","https://openalex.org/W2054270551","https://openalex.org/W2054290330","https://openalex.org/W2054356183","https://openalex.org/W2054851194","https://openalex.org/W2056195685","https://openalex.org/W2056937635","https://openalex.org/W2057515381","https://openalex.org/W2060637135","https://openalex.org/W2061013234","https://openalex.org/W2061361921","https://openalex.org/W2061713465","https://openalex.org/W2061925808","https://openalex.org/W2063051075","https://openalex.org/W2063896117","https://openalex.org/W2064609154","https://openalex.org/W2064715676","https://openalex.org/W2065060753","https://openalex.org/W2065133286","https://openalex.org/W2065982049","https://openalex.org/W2066092624","https://openalex.org/W2068711980","https://openalex.org/W2069532898","https://openalex.org/W2070253438","https://openalex.org/W2070616232","https://openalex.org/W2072608022","https://openalex.org/W2075171810","https://openalex.org/W2076973731","https://openalex.org/W2077338443","https://openalex.org/W2078535741","https://openalex.org/W2078721766","https://openalex.org/W2079075112","https://openalex.org/W2081152882","https://openalex.org/W2084600602","https://openalex.org/W2085135498","https://openalex.org/W2085792867","https://openalex.org/W2085919583","https://openalex.org/W2086102771","https://openalex.org/W2086910750","https://openalex.org/W2087566616","https://openalex.org/W2087647782","https://openalex.org/W2088321655","https://openalex.org/W2089286420","https://openalex.org/W2089453915","https://openalex.org/W2090600090","https://openalex.org/W2091649205","https://openalex.org/W2091759162","https://openalex.org/W2091994022","https://openalex.org/W2093894290","https://openalex.org/W2094229974","https://openalex.org/W2095236486","https://openalex.org/W2097511872","https://openalex.org/W2097592029","https://openalex.org/W2097794068","https://openalex.org/W2098029318","https://openalex.org/W2099862428","https://openalex.org/W2099910150","https://openalex.org/W2101201102","https://openalex.org/W2101641567","https://openalex.org/W2102071276","https://openalex.org/W2102106861","https://openalex.org/W2102312517","https://openalex.org/W2102313291","https://openalex.org/W2102897116","https://openalex.org/W2102979586","https://openalex.org/W2103116278","https://openalex.org/W2104564418","https://openalex.org/W2105072567","https://openalex.org/W2105362864","https://openalex.org/W2105422846","https://openalex.org/W2108312372","https://openalex.org/W2108462699","https://openalex.org/W2109692501","https://openalex.org/W2110442637","https://openalex.org/W2111038792","https://openalex.org/W2111369450","https://openalex.org/W2111385165","https://openalex.org/W2112375566","https://openalex.org/W2113328569","https://openalex.org/W2113652219","https://openalex.org/W2113824754","https://openalex.org/W2113868760","https://openalex.org/W2114944602","https://openalex.org/W2115027228","https://openalex.org/W2116351973","https://openalex.org/W2117763395","https://openalex.org/W2118582266","https://openalex.org/W2118639034","https://openalex.org/W2119016586","https://openalex.org/W2120282127","https://openalex.org/W2120289695","https://openalex.org/W2120949271","https://openalex.org/W2123106337","https://openalex.org/W2123585146","https://openalex.org/W2123936150","https://openalex.org/W2124230153","https://openalex.org/W2125807056","https://openalex.org/W2126498542","https://openalex.org/W2127019764","https://openalex.org/W2127104460","https://openalex.org/W2127162288","https://openalex.org/W2127283831","https://openalex.org/W2127924963","https://openalex.org/W2129775201","https://openalex.org/W2129950813","https://openalex.org/W2130120054","https://openalex.org/W2130421055","https://openalex.org/W2130796329","https://openalex.org/W2130815938","https://openalex.org/W2130850001","https://openalex.org/W2131541226","https://openalex.org/W2132198142","https://openalex.org/W2132242617","https://openalex.org/W2132681961","https://openalex.org/W2132762612","https://openalex.org/W2133773424","https://openalex.org/W2133824204","https://openalex.org/W2134293572","https://openalex.org/W2134920653","https://openalex.org/W2135125559","https://openalex.org/W2135684554","https://openalex.org/W2135804102","https://openalex.org/W2136054920","https://openalex.org/W2137842897","https://openalex.org/W2138810477","https://openalex.org/W2138878645","https://openalex.org/W2139002144","https://openalex.org/W2139692118","https://openalex.org/W2140038597","https://openalex.org/W2140111840","https://openalex.org/W2141901389","https://openalex.org/W2142179136","https://openalex.org/W2143716053","https://openalex.org/W2144354010","https://openalex.org/W2144590229","https://openalex.org/W2145270527","https://openalex.org/W2145419446","https://openalex.org/W2145642828","https://openalex.org/W2145666707","https://openalex.org/W2145734899","https://openalex.org/W2146788074","https://openalex.org/W2147465183","https://openalex.org/W2147955643","https://openalex.org/W2151499811","https://openalex.org/W2154969010","https://openalex.org/W2155235961","https://openalex.org/W2156281856","https://openalex.org/W2158969881","https://openalex.org/W2159270178","https://openalex.org/W2159482845","https://openalex.org/W2160697532","https://openalex.org/W2161184363","https://openalex.org/W2161620018","https://openalex.org/W2162558399","https://openalex.org/W2164153195","https://openalex.org/W2164314657","https://openalex.org/W2164324917","https://openalex.org/W2166370133","https://openalex.org/W2166834443","https://openalex.org/W2168761911","https://openalex.org/W2169198250","https://openalex.org/W2169224393","https://openalex.org/W2170397513","https://openalex.org/W2171631681","https://openalex.org/W2173681478","https://openalex.org/W2186918019","https://openalex.org/W2198678228","https://openalex.org/W2231081458","https://openalex.org/W2255238810","https://openalex.org/W2293412032","https://openalex.org/W2313677450","https://openalex.org/W2319725616","https://openalex.org/W2327238535","https://openalex.org/W2327573495","https://openalex.org/W2328529137","https://openalex.org/W2335922553","https://openalex.org/W2337109902","https://openalex.org/W2341665659","https://openalex.org/W2342825661","https://openalex.org/W2400712338","https://openalex.org/W2411757152","https://openalex.org/W2413107236","https://openalex.org/W2413417214","https://openalex.org/W2436485827","https://openalex.org/W2725187802","https://openalex.org/W4240687645"],"related_works":["https://openalex.org/W2319725616","https://openalex.org/W1532505468","https://openalex.org/W2169198250","https://openalex.org/W1997737160","https://openalex.org/W2059179695","https://openalex.org/W2144354010","https://openalex.org/W2023806016","https://openalex.org/W1996584884","https://openalex.org/W2948394799","https://openalex.org/W2606430072"],"abstract_inverted_index":{"ABCD2":[0],"(D2)":[1],"has":[2,36,189],"been":[3,37,191],"proposed":[4,175],"as":[5,40,176],"a":[6,32,41,55,121,177,204,238,242,253,303],"peroxisomal":[7,178],"long-chain":[8],"acyl-CoA":[9],"transporter":[10],"that":[11,35,99,148,157,298,308],"is":[12,27,54,300],"essential":[13],"for":[14,69],"very":[15],"long":[16],"chain":[17],"fatty":[18],"acid":[19],"metabolism.":[20],"In":[21],"the":[22,46,112,130,166,180,227,247,267,274,281,285,320],"livers":[23],"of":[24,48,57,74,78,95,101,114,118,124,132,168,183,199,223,229,237,244,252,266,276,280,287,306],"mice,":[25],"D2":[26,53,62,75,102,115,144,149,230,255,282,299],"highly":[28],"induced":[29],"by":[30,143],"fenofibrate,":[31],"PPAR\u03b1":[33,86],"ligand":[34],"widely":[38],"used":[39],"lipid":[42,83],"lowering":[43],"agent":[44],"in":[45,120,186,262],"treatment":[47,128],"hypertriglyceridemia.":[49],"To":[50],"determine":[51],"if":[52],"modifier":[56],"fibrate":[58,107],"responses,":[59],"wild-type":[60],"and":[61,135,217,241,250,256,294,313,319],"deficient":[63],"mice":[64],"were":[65,141],"treated":[66],"with":[67,82,193,207,235,317],"fenofibrate":[68],"14":[70],"days.":[71],"The":[72],"absence":[73],"altered":[76],"expression":[77],"gene":[79],"clusters":[80],"associated":[81,289],"metabolism,":[84],"including":[85,214],"signaling.":[87],"Using":[88],"3T3-L1":[89],"adipocytes,":[90],"which":[91],"express":[92],"high":[93],"levels":[94],"D2,":[96,184,208],"we":[97],"confirmed":[98,226,273],"knock-down":[100],"modified":[103],"genomic":[104,152],"responses":[105,153],"to":[106,154,164,302],"treatment.":[108],"We":[109,146,296],"next":[110],"evaluated":[111],"impact":[113],"on":[116,170,232],"effects":[117,140,159,167],"fibrates":[119,169],"mouse":[122,200,263],"model":[123],"dietinduced":[125],"obesity.":[126],"Fenofibrate":[127],"opposed":[129],"development":[131],"obesity,":[133],"hypertriglyceridemia,":[134],"insulin":[136],"resistance.":[137],"However,":[138],"these":[139,158],"unaffected":[142],"genotype.":[145],"concluded":[147],"can":[150],"modulate":[151],"fibrates,":[155],"but":[156,209],"are":[160],"not":[161,190],"sufficiently":[162],"robust":[163],"alter":[165],"diet-induced":[171],"obesity":[172],"phenotypes.":[173],"Although":[174],"transporter,":[179],"intracellular":[181],"localization":[182],"especially":[185],"adipose":[187,201,271],"tissue,":[188],"validated":[192],"direct":[194],"experimental":[195],"evidence.":[196],"Sequential":[197],"centrifugation":[198],"homogenates":[202],"generated":[203],"fraction":[205,225],"enriched":[206],"lacked":[210],"well-known":[211],"peroxisome":[212,311],"markers":[213],"catalase,":[215],"PEX19,":[216],"ABCD3":[218],"(D3).":[219],"Electron":[220],"microscopic":[221],"imaging":[222],"this":[224],"presence":[228,286],"protein":[231],"an":[233],"organelle":[234],"evidence":[236],"dense":[239],"matrix":[240],"diameter":[243],"~200":[245],"nm,":[246],"typical":[248],"structure":[249],"size":[251],"microperoxisome.":[254],"PEX19":[257],"antibodies":[258],"recognized":[259],"distinct":[260,304],"structures":[261],"adipose.":[264],"Immunoisolation":[265],"D2-containing":[268],"compartment":[269,283],"from":[270],"tissue":[272],"scarcity":[275],"PEX19.":[277],"Proteomic":[278],"profiling":[279],"revealed":[284],"proteins":[288,312],"peroxisome,":[290],"endoplasmic":[291],"reticulum":[292],"(ER),":[293],"mitochondria.":[295],"conclude":[297],"localized":[301],"subclass":[305],"peroxisomes":[307],"lack":[309],"many":[310],"may":[314],"physically":[315],"associate":[316],"mitochondria":[318],"ER.":[321]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}