{"id":"https://openalex.org/W1933800266","doi":"https://doi.org/10.1128/mcb.5.12.3634-3639.1985","title":"Structure of the Rat \u03b11-Acid Glycoprotein Gene","display_name":"Structure of the Rat \u03b11-Acid Glycoprotein Gene","publication_year":1985,"publication_date":"1985-12-01","ids":{"openalex":"https://openalex.org/W1933800266","doi":"https://doi.org/10.1128/mcb.5.12.3634-3639.1985","mag":"1933800266","pmid":"https://pubmed.ncbi.nlm.nih.gov/2943986","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/369197"},"language":"en","primary_location":{"id":"doi:10.1128/mcb.5.12.3634-3639.1985","doi":"https://doi.org/10.1128/mcb.5.12.3634-3639.1985","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mcb.5.12.3634-3639.1985","pdf_url":null,"source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/369197","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003967916","display_name":"Yucheng Liao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yu-Cheng J. Liao","raw_affiliation_strings":["Department of Pathology, School of Medicine, University of California, San Francisco, California 94143"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Medicine, University of California, San Francisco, California 94143","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088766033","display_name":"John M. Taylor","orcid":"https://orcid.org/0000-0002-4275-077X","observed_orcids":["https://orcid.org/0000-0002-4275-077X"]},"institutions":[{"id":"https://openalex.org/I1295908608","display_name":"San Francisco General Hospital","ror":"https://ror.org/05j8x4n38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295908608"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John M. Taylor","raw_affiliation_strings":["Gladstone Foundation, San Francisco General Hospital, San Francisco, California 94140"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gladstone Foundation, San Francisco General Hospital, San Francisco, California 94140","institution_ids":["https://openalex.org/I1295908608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060971800","display_name":"James L. Vannice","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183934855","display_name":"Genentech","ror":"https://ror.org/04gndp242","country_code":"US","type":"company","lineage":["https://openalex.org/I118019719","https://openalex.org/I129302853","https://openalex.org/I183934855"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James L. Vannice","raw_affiliation_strings":["Department of Molecular Biology, Genentech Inc., South San Francisco, California 94080"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Genentech Inc., South San Francisco, California 94080","institution_ids":["https://openalex.org/I183934855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083391540","display_name":"Gary A. Clawson","orcid":"https://orcid.org/0000-0002-4832-9193","observed_orcids":["https://orcid.org/0000-0002-4832-9193"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary A. Clawson","raw_affiliation_strings":["Department of Pathology, School of Medicine, University of California, San Francisco, California 94143"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Medicine, University of California, San Francisco, California 94143","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108365256","display_name":"Edward A. Smuckler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edward A. Smuckler","raw_affiliation_strings":["Department of Pathology, School of Medicine, University of California, San Francisco, California 94143"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Medicine, University of California, San Francisco, California 94143","institution_ids":["https://openalex.org/I180670191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.5127,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.82172204,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":"12","first_page":"3634","last_page":"3639"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.948199987411499,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.948199987411499,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.014399999752640724,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpha-1-acid-glycoprotein","display_name":"alpha-1-acid glycoprotein","score":0.9629999995231628},{"id":"https://openalex.org/keywords/gene-structure","display_name":"gene structure","score":0.8090000152587891},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.7390000224113464},{"id":"https://openalex.org/keywords/nucleotide-sequence","display_name":"nucleotide sequence","score":0.859000027179718},{"id":"https://openalex.org/keywords/exons","display_name":"exons","score":0.652999997138977},{"id":"https://openalex.org/keywords/tata-box","display_name":"TATA box","score":0.9879999756813049},{"id":"https://openalex.org/keywords/polyadenylation-signal","display_name":"polyadenylation signal","score":0.8790000081062317},{"id":"https://openalex.org/keywords/transcription-start-site","display_name":"transcription start sites","score":0.8450000286102295},{"id":"https://openalex.org/keywords/glucocorticoid-receptor-binding-site","display_name":"glucocorticoid receptor binding site","score":0.9330000281333923}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8528802394866943},{"id":"https://openalex.org/C65888428","wikidata":"https://www.wikidata.org/wiki/Q1413955","display_name":"TATA box","level":5,"score":0.7175118327140808},{"id":"https://openalex.org/C142575336","wikidata":"https://www.wikidata.org/wiki/Q412148","display_name":"Polyadenylation","level":4,"score":0.6828140020370483},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6509066224098206},{"id":"https://openalex.org/C176990463","wikidata":"https://www.wikidata.org/wiki/Q1854186","display_name":"Start codon","level":4,"score":0.6368488073348999},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6074371337890625},{"id":"https://openalex.org/C185581394","wikidata":"https://www.wikidata.org/wiki/Q145911","display_name":"Base pair","level":3,"score":0.576449990272522},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5213811993598938},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.5106855034828186},{"id":"https://openalex.org/C84148353","wikidata":"https://www.wikidata.org/wiki/Q863908","display_name":"Nucleic acid sequence","level":3,"score":0.4617692530155182},{"id":"https://openalex.org/C179716448","wikidata":"https://www.wikidata.org/wiki/Q2508056","display_name":"CAAT box","level":5,"score":0.4569992125034332},{"id":"https://openalex.org/C91779695","wikidata":"https://www.wikidata.org/wiki/Q3780824","display_name":"Coding region","level":3,"score":0.43264734745025635},{"id":"https://openalex.org/C20580545","wikidata":"https://www.wikidata.org/wiki/Q28354","display_name":"Stop codon","level":3,"score":0.4287432134151459},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.3763381540775299},{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.21623495221138},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.17688462138175964}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009961","descriptor_name":"Orosomucoid","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010582","descriptor_name":"Bacteriophage lambda","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/mcb.5.12.3634-3639.1985","doi":"https://doi.org/10.1128/mcb.5.12.3634-3639.1985","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mcb.5.12.3634-3639.1985","pdf_url":null,"source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:1295042","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/369197","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:369197","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/369197","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Cell Biol","raw_type":"Text"},{"id":"pmid:2943986","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2943986","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and cellular biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1295042","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/369197","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G8052816122","display_name":null,"funder_award_id":"CA-21141","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W193405512","https://openalex.org/W1522050581","https://openalex.org/W1581207403","https://openalex.org/W1969600436","https://openalex.org/W1971356495","https://openalex.org/W1974003378","https://openalex.org/W1976782468","https://openalex.org/W1988432444","https://openalex.org/W1999912636","https://openalex.org/W2017455405","https://openalex.org/W2017830116","https://openalex.org/W2026131405","https://openalex.org/W2053885618","https://openalex.org/W2062248000","https://openalex.org/W2063450941","https://openalex.org/W2063991006","https://openalex.org/W2064092862","https://openalex.org/W2067835109","https://openalex.org/W2068551847","https://openalex.org/W2078038295","https://openalex.org/W2088856105","https://openalex.org/W2134305122","https://openalex.org/W2138270253","https://openalex.org/W2316352740","https://openalex.org/W2435903168","https://openalex.org/W4238112077","https://openalex.org/W4323528101"],"related_works":["https://openalex.org/W3172490603","https://openalex.org/W2460826944","https://openalex.org/W1982060337","https://openalex.org/W1994093021","https://openalex.org/W2089606601","https://openalex.org/W1522050581","https://openalex.org/W1967379854","https://openalex.org/W1551655244","https://openalex.org/W1607210553","https://openalex.org/W2041003192"],"abstract_inverted_index":{"The":[0,72,84],"complete":[1],"nucleotide":[2],"sequence":[3],"of":[4,67],"the":[5,54,65,68,96],"rat":[6],"alpha":[7],"1-acid":[8],"glycoprotein":[9],"gene":[10,32,85],"has":[11],"been":[12],"determined":[13],"from":[14,47,64,81],"an":[15],"isolated":[16],"lambda":[17],"recombinant":[18],"bacteriophage.":[19],"Southern":[20],"blot":[21],"analysis":[22],"and":[23,39,51,94],"DNA":[24],"sequencing":[25],"indicate":[26],"that":[27],"there":[28],"is":[29,40],"only":[30],"one":[31],"per":[33],"genome;":[34],"it":[35],"contains":[36,86],"six":[37],"exons":[38],"located":[41],"within":[42],"a":[43,48],"3,200-base-pair":[44],"fragment":[45],"starting":[46],"TATA":[49,73],"box":[50,74],"extending":[52],"to":[53],"polyadenylation":[55],"signal":[56],"AATAAA.":[57],"Transcription":[58],"starts":[59],"37":[60],"base":[61,78],"pairs":[62,79],"upstream":[63,80],"beginning":[66],"translation":[69],"codon":[70],"ATG.":[71],"(TATAAA)":[75],"lies":[76],"26":[77],"this":[82],"site.":[83],"several":[87],"potential":[88],"glucocorticoid":[89],"receptor-binding":[90],"sites,":[91],"both":[92],"inside":[93],"outside":[95],"structural":[97],"gene.":[98]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}