{"id":"https://openalex.org/W193014646","doi":null,"title":"[The clinical relationship between symptoms and the final diagnosis in general practice, determined by means of posterior probabilities calculated on the basis of the Transition Project].","display_name":"[The clinical relationship between symptoms and the final diagnosis in general practice, determined by means of posterior probabilities calculated on the basis of the Transition Project].","publication_year":2005,"publication_date":"2005-11-12","ids":{"openalex":"https://openalex.org/W193014646","mag":"193014646","pmid":"https://pubmed.ncbi.nlm.nih.gov/16320668"},"language":"nl","primary_location":{"id":"pmid:16320668","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16320668","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nederlands tijdschrift voor geneeskunde","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108351441","display_name":"H Lamberts","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"H Lamberts","raw_affiliation_strings":["Academisch Medisch Centrum/Universiteit van Amsterdam, divisie Klinische Methoden & Public Health, afd. Huisartsgeneeskunde, Amsterdam. henk.lamberts@planet.nl"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academisch Medisch Centrum/Universiteit van Amsterdam, divisie Klinische Methoden & Public Health, afd. Huisartsgeneeskunde, Amsterdam. henk.lamberts@planet.nl","institution_ids":["https://openalex.org/I2802928900","https://openalex.org/I887064364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108534603","display_name":"S. Oskam","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S K Oskam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5051133666","display_name":"Inge M Okkes","orcid":"https://orcid.org/0000-0002-2322-4256","observed_orcids":["https://orcid.org/0000-0002-2322-4256"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I M Okkes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0344,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.81372158,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"149","issue":"46","first_page":"2566","last_page":"72"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11590","display_name":"Primary Care and Health Outcomes","score":0.7372999787330627,"subfield":{"id":"https://openalex.org/subfields/2714","display_name":"Family Practice"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11590","display_name":"Primary Care and Health Outcomes","score":0.7372999787330627,"subfield":{"id":"https://openalex.org/subfields/2714","display_name":"Family Practice"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12246","display_name":"Chronic Disease Management Strategies","score":0.12330000102519989,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12574","display_name":"Clinical Reasoning and Diagnostic Skills","score":0.0771000012755394,"subfield":{"id":"https://openalex.org/subfields/2714","display_name":"Family Practice"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/posterior-probability","display_name":"posterior probability","score":0.8330000042915344},{"id":"https://openalex.org/keywords/transition-project","display_name":"transition projects","score":0.7620000243186951},{"id":"https://openalex.org/keywords/general-practice","display_name":"general practice","score":0.7459999918937683},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.781000018119812},{"id":"https://openalex.org/keywords/odds-ratio","display_name":"odds ratio","score":0.6499999761581421},{"id":"https://openalex.org/keywords/otitis-media","display_name":"otitis media","score":0.8169999718666077},{"id":"https://openalex.org/keywords/otalgia","display_name":"otalgia","score":0.8820000290870667},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.7170000076293945},{"id":"https://openalex.org/keywords/dyspnea","display_name":"dyspnea","score":0.9729999899864197},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.7910000085830688},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9879999756813049},{"id":"https://openalex.org/keywords/ankle-edema","display_name":"ankle edema","score":0.9589999914169312},{"id":"https://openalex.org/keywords/international-classification-of-primary-care","display_name":"International Classification of Primary Care","score":0.7720000147819519},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.414000004529953},{"id":"https://openalex.org/keywords/clinical-decision-support","display_name":"clinical decision support","score":0.578000009059906},{"id":"https://openalex.org/keywords/chronic-illness-care","display_name":"chronic care","score":0.4269999861717224},{"id":"https://openalex.org/keywords/primary-care-databases","display_name":"primary care databases","score":0.30399999022483826}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8363986015319824},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.7230809330940247},{"id":"https://openalex.org/C143095724","wikidata":"https://www.wikidata.org/wiki/Q515895","display_name":"Odds","level":3,"score":0.646375834941864},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.5937449932098389},{"id":"https://openalex.org/C534262118","wikidata":"https://www.wikidata.org/wiki/Q177719","display_name":"Medical diagnosis","level":2,"score":0.5358660817146301},{"id":"https://openalex.org/C2776439223","wikidata":"https://www.wikidata.org/wiki/Q480700","display_name":"Otitis","level":2,"score":0.49019819498062134},{"id":"https://openalex.org/C144494922","wikidata":"https://www.wikidata.org/wiki/Q6547272","display_name":"Likelihood ratios in diagnostic testing","level":3,"score":0.42294007539749146},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.36899083852767944},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.25505727529525757},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.2445116639137268},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23678860068321228},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.11647504568099976},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.1071525514125824}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005194","descriptor_name":"Family Practice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010818","descriptor_name":"Practice Patterns, Physicians'","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017677","descriptor_name":"Age Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017678","descriptor_name":"Sex Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038801","descriptor_name":"International Classification of Diseases","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:16320668","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16320668","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nederlands tijdschrift voor geneeskunde","raw_type":"Comparative Study"},{"id":"mag:193014646","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16320668","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2122560123","https://openalex.org/W7096313542","https://openalex.org/W4387092892","https://openalex.org/W2022339522","https://openalex.org/W2054629726","https://openalex.org/W2068505457","https://openalex.org/W7162793874","https://openalex.org/W1823309505","https://openalex.org/W2172577020","https://openalex.org/W2419420613"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"determine":[2,142,429],"how,":[3],"with":[4,89,220,243,337,342],"the":[5,8,11,27,31,54,64,70,73,77,86,97,104,114,122,125,144,147,150,172,187,201,206,213,223,249,255,262,272,282,293,297,308,324,330,333,363,377,380,383,413,416,419,430],"aid":[6],"of":[7,10,30,34,53,57,72,92,100,106,116,124,128,131,181,253,258,284,296,379,407,415,418,433],"database":[9,84,331,417],"Transition":[12,78,420],"Project":[13,79,421],"(www.transitionproject.nl),":[14],"one":[15],"can":[16,289],"calculate":[17],"posterior":[18,98,151,166,192,215,273,287,381,410],"probabilities":[19,167,288,411],"for":[20,67,85,171,238,292,304,335,344,389,425],"general":[21,46,74,298,426],"practice":[22],"that":[23,159,332,343],"provide":[24,290],"insight":[25],"into":[26],"clinical":[28,294,431],"significance":[29],"simultaneous":[32,126],"occurrence":[33,127],"two":[35,43],"events":[36],"(a":[37],"symptom":[38,110,250],"and":[39,69,149,183,191,286,359,399,409],"a":[40,83,90,101,107,135,154,162,301,368],"diagnosis,":[41],"or":[42,109,158],"diseases)":[44],"in":[45,76,82,95,103,113,121,134,177,205,240,261,307],"practice.":[47],"DESIGN:":[48],"Descriptive.":[49],"METHOD:":[50],"The":[51,235,405],"use":[52],"'International":[55],"classification":[56],"primary":[58],"care'":[59],"(ICPC)":[60],"to":[61,141,323,428],"code":[62],"both":[63],"patient's":[65],"reason":[66],"encounter":[68],"diagnosis":[71,102,202],"practitioner":[75],"has":[80],"resulted":[81],"period":[87],"1985-2002":[88],"total":[91],"201,127":[93],"patient-years,":[94],"which":[96],"probability":[99,152,216,257,274],"presence":[105],"complaint":[108],"is":[111,138,161,367],"available":[112],"form":[115],"an":[117,316],"odds":[118,236,385],"ratio.":[119],"Also":[120],"case":[123],"2":[129],"episodes":[130],"care":[132,334],"(comorbidity)":[133],"patient":[136],"it":[137,160,423],"now":[139],"possible":[140,424],"whether":[143,365],"ratio":[145,237],"between":[146],"prior":[148,190,256,285,408],"indicates":[153],"clinically":[155,369],"relevant":[156,370],"relationship":[157,371],"chance":[163],"finding.":[164],"Such":[165],"have":[168],"been":[169],"calculated":[170],"conditions":[173],"otitis":[174],"media,":[175],"hypertension":[176,239],"diabetes":[178,244,349],"mellitus,":[179,350],"shortness":[180],"breath":[182],"heart":[184,259,305,338,353],"failure.":[185],"In":[186,279],"calculation":[188,406],"ofthe":[189],"probabilities,":[193],"only":[194,373],"'certain'":[195],"diagnoses":[196],"were":[197,387],"used.":[198],"RESULTS:":[199],"For":[200],"'otitis":[203],"media'":[204],"age":[207,263,309],"group":[208,264,310],"0-4":[209],"years,":[210,312],"otalgia":[211],"had":[212],"highest":[214,384],"(odds":[217,228],"ratio:":[218,229],"15.77),":[219],"discharge":[221],"from":[222,329],"ear":[224],"taking":[225],"second":[226],"place":[227],"8.59).":[230],"'Fever'":[231],"contributed":[232,321],"almost":[233],"nothing.":[234],"45-74-year-old":[241],"women":[242],"mellitus":[245],"was":[246,251,267,275,327],"3.42.":[247],"When":[248],"'shortness":[252],"breath',":[254],"failure":[260,306,339],"45-64":[265],"years":[266],"relatively":[268,276],"low":[269],"(2.0)":[270],"but":[271],"high":[277],"(24.2).":[278],"this":[280],"way,":[281],"combination":[283],"support":[291],"work":[295],"practitioner.":[299],"As":[300],"predictive":[302],"variable":[303],"65-74":[311],"'ankle":[313],"oedema'":[314],"played":[315],"important":[317],"role":[318],"while":[319],"'fatigue'":[320],"nothing":[322],"diagnosis.":[325],"It":[326],"apparent":[328],"patients":[336],"often":[340],"coincided":[341],"chronic":[345,355],"diseases":[346],"such":[347],"as":[348],"hypertension,":[351],"ischaemic":[352],"disease,":[354],"obstructive":[356,395],"pulmonary":[357,396],"disease":[358],"atrial":[360],"fibrillation.":[361],"But":[362],"question":[364],"there":[366],"could":[372],"be":[374],"answered":[375],"on":[376,412],"basis":[378,414],"probabilities:":[382],"ratio's":[386],"found":[388],"'atrial":[390],"fibrillation/atrial":[391],"flutter'":[392],"(32.5),":[393],"'chronic":[394,400],"disease'":[397],"(22.5)":[398],"skin":[401],"ulcer'":[402],"(20.2).":[403],"CONCLUSION:":[404],"makes":[422],"practitioners":[427],"relevance":[432],"their":[434],"observations.":[435]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}