{"id":"https://openalex.org/W192989192","doi":"https://doi.org/10.18926/amo/31818","title":"Human intestinal spirochetosis accompanied by human immunodeficiency virus infection: a case report.","display_name":"Human intestinal spirochetosis accompanied by human immunodeficiency virus infection: a case report.","publication_year":2009,"publication_date":"2009-08-01","ids":{"openalex":"https://openalex.org/W192989192","doi":"https://doi.org/10.18926/amo/31818","mag":"192989192","pmid":"https://pubmed.ncbi.nlm.nih.gov/19727207"},"language":"en","primary_location":{"id":"pmid:19727207","doi":"https://doi.org/10.18926/amo/31818","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19727207","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta medica Okayama","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ousar.lib.okayama-u.ac.jp/31818","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025260836","display_name":"Masaaki Higashiyama","orcid":"https://orcid.org/0000-0002-3206-4055","observed_orcids":["https://orcid.org/0000-0002-3206-4055"]},"institutions":[{"id":"https://openalex.org/I4405283087","display_name":"Japan Self-Defense Forces Hospital Yokosuka","ror":"https://ror.org/00ztkvj70","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405273344","https://openalex.org/I4405283087"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaaki Higashiyama","raw_affiliation_strings":["Division of Medicine, Japan Self Defense Forces Hospital Yokosuka, Yokosuka, Kanagawa 237-0071, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medicine, Japan Self Defense Forces Hospital Yokosuka, Yokosuka, Kanagawa 237-0071, Japan","institution_ids":["https://openalex.org/I4405283087"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101494253","display_name":"Sho Ogata","orcid":"https://orcid.org/0000-0002-2206-8482","observed_orcids":["https://orcid.org/0000-0002-2206-8482"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sho Ogata","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113557426","display_name":"Yoshikazu Adachi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yoshikazu Adachi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009631334","display_name":"Junichiro Nishiyama","orcid":"https://orcid.org/0000-0002-0704-7827","observed_orcids":["https://orcid.org/0000-0002-0704-7827"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Junichiro Nishiyama","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077470314","display_name":"Ichiyo Ohara","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ichiyo Ohara","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075542212","display_name":"Meri Okamura","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Meri Okamura","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067871082","display_name":"Koji Matsuzaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Koji Matsuzaki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015327328","display_name":"Yasushi Okusa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yasushi Okusa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009961423","display_name":"Kimiya Sato","orcid":"https://orcid.org/0000-0002-8534-8852","observed_orcids":["https://orcid.org/0000-0002-8534-8852"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kimiya Sato","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074657080","display_name":"Ryota Hokari","orcid":"https://orcid.org/0000-0002-8511-2540","observed_orcids":["https://orcid.org/0000-0002-8511-2540"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ryota Hokari","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110478815","display_name":"Soichiro Miura","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Soichiro Miura","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.5612,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.809605,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"63","issue":"4","first_page":"217","last_page":"21"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13791","display_name":"Veterinary medicine and infectious diseases","score":0.8252000212669373,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13791","display_name":"Veterinary medicine and infectious diseases","score":0.8252000212669373,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11086","display_name":"Parasitic Infections and Diagnostics","score":0.0632999986410141,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11899","display_name":"Brucella: diagnosis, epidemiology, treatment","score":0.015699999406933784,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intestinal-spirochetosis","display_name":"intestinal spirochetosis","score":0.9160000085830688},{"id":"https://openalex.org/keywords/brachyspira-aalborgi","display_name":"Brachyspira aalborgi","score":0.9900000095367432},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.8149999976158142},{"id":"https://openalex.org/keywords/coinfection","display_name":"co-infection","score":0.7609999775886536},{"id":"https://openalex.org/keywords/syphilis","display_name":"syphilis","score":0.8220000267028809},{"id":"https://openalex.org/keywords/entamoeba-histolytica","display_name":"Entamoeba histolytica","score":0.7770000100135803},{"id":"https://openalex.org/keywords/colonic-biopsy","display_name":"colonic biopsy","score":0.800000011920929},{"id":"https://openalex.org/keywords/16s-rrna-gene-pcr","display_name":"16S rRNA PCR","score":0.8309999704360962},{"id":"https://openalex.org/keywords/serological-diagnosis","display_name":"serological diagnosis","score":0.49799999594688416}],"concepts":[{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.6923172473907471},{"id":"https://openalex.org/C2776983459","wikidata":"https://www.wikidata.org/wiki/Q41083","display_name":"Syphilis","level":3,"score":0.6376473307609558},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5831794738769531},{"id":"https://openalex.org/C2778435480","wikidata":"https://www.wikidata.org/wiki/Q840387","display_name":"Colonoscopy","level":4,"score":0.5393836498260498},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.4552149176597595},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.44055670499801636},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.4356393814086914},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.37957626581192017},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37409308552742004},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.37321972846984863},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3556693494319916},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.35437285900115967},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26238924264907837},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.11002391576766968},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.07330003380775452},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007410","descriptor_name":"Intestinal Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013145","descriptor_name":"Spirochaetales Infections","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D017400","descriptor_name":"Brachyspira","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true}],"locations_count":4,"locations":[{"id":"pmid:19727207","doi":"https://doi.org/10.18926/amo/31818","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19727207","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta medica Okayama","raw_type":"Case Reports"},{"id":"pmh:oai:EPrintsOUDIR.lib.okayama-u.ac.jp:31818","doi":"https://doi.org/10.18926/amo/31818","is_oa":false,"landing_page_url":"https://ousar.lib.okayama-u.ac.jp/31818","pdf_url":null,"source":{"id":"https://openalex.org/S4377196325","display_name":"Okayama University Scientific Achievement Repository (Okayama University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I163770644","host_organization_name":"Okayama University","host_organization_lineage":["https://openalex.org/I163770644"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta Medica Okayama","raw_type":"Journal Article"},{"id":"pmh:oai:irdb.nii.ac.jp:01081:0000647233","doi":"https://doi.org/10.18926/amo/31818","is_oa":true,"landing_page_url":"https://ousar.lib.okayama-u.ac.jp/31818","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta Medica Okayama","raw_type":"journal article"},{"id":"mag:192989192","doi":"https://doi.org/10.18926/amo/31818","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19727207","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:irdb.nii.ac.jp:01081:0000647233","doi":"https://doi.org/10.18926/amo/31818","is_oa":true,"landing_page_url":"https://ousar.lib.okayama-u.ac.jp/31818","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta Medica Okayama","raw_type":"journal article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W29586013","https://openalex.org/W177447356","https://openalex.org/W1506970368","https://openalex.org/W1897792699","https://openalex.org/W2013026761","https://openalex.org/W2025991144","https://openalex.org/W2033832975","https://openalex.org/W2044558153","https://openalex.org/W2044792528","https://openalex.org/W2079145024","https://openalex.org/W2115240195","https://openalex.org/W2124897848"],"related_works":["https://openalex.org/W2066824275","https://openalex.org/W2978939105","https://openalex.org/W4387751309","https://openalex.org/W2921578743","https://openalex.org/W2887563413","https://openalex.org/W4316078133","https://openalex.org/W2156769043","https://openalex.org/W4316078175","https://openalex.org/W4403725546","https://openalex.org/W4285025823"],"abstract_inverted_index":{"We":[0],"present":[1,57],"a":[2,51,84],"middle-aged,":[3],"heterosexual":[4],"Japanese":[5],"man":[6],"with":[7,135],"mixed":[8],"infections":[9],"including":[10],"human":[11,21,59,136],"intestinal":[12,60,80,137],"spirochetosis,":[13,138],"which":[14],"led":[15],"us":[16],"to":[17],"the":[18,39,56,79,88,107],"detection":[19],"of":[20,71,78],"immunodeficiency":[22],"virus":[23],"(HIV)":[24],"infection.":[25],"The":[26],"patient":[27],"had":[28],"syphilis":[29],"without":[30],"related":[31],"physical":[32],"or":[33],"neurological":[34],"findings.":[35],"An":[36],"examination":[37,70,77,129],"for":[38,42,87,90,112,130],"serum":[40],"antibody":[41,89],"HIV":[43,91,119,131],"performed":[44],"9":[45],"years":[46],"previously":[47],"was":[48,92,101],"negative.":[49],"In":[50,94],"complete":[52],"medical":[53],"checkup":[54],"at":[55,122],"time,":[58],"spirochetosis":[61],"and":[62,75,106],"unspecified":[63],"entamebic":[64],"cysts":[65],"were":[66],"suggested":[67],"by":[68,97,103],"histological":[69],"colonic":[72],"biopsy":[73],"material":[74],"parasitic":[76],"fluid,":[81],"respectively.":[82],"Moreover,":[83],"serological":[85],"test":[86],"positive.":[93],"specimens":[95],"obtained":[96],"colonoscopy,":[98],"Brachyspira":[99],"aalborgi":[100],"diagnosed":[102],"ultrastructural":[104],"study":[105],"polymerase":[108],"chain":[109],"reaction":[110],"method":[111],"bacterial":[113],"16S":[114],"ribosomal":[115],"deoxyribonucleic":[116],"acid.":[117],"Although":[118],"infection":[120,132],"remains":[121],"low":[123],"prevalence":[124],"in":[125,133],"Japan,":[126],"we":[127],"recommend":[128],"patients":[134],"especially":[139],"when":[140],"other":[141],"co-infections":[142],"are":[143],"apparent.":[144]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}