{"id":"https://openalex.org/W1929614903","doi":null,"title":"Evaluation of antidepressant effect of ethanolic extract of Rosa damascena using forced swimming test","display_name":"Evaluation of antidepressant effect of ethanolic extract of Rosa damascena using forced swimming test","publication_year":2011,"publication_date":"2011-12-01","ids":{"openalex":"https://openalex.org/W1929614903","mag":"1929614903"},"language":"en","primary_location":{"id":"pmh:oai:doaj.org/article:c99b87a9a47b4e598e5512cd677bd9a9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c99b87a9a47b4e598e5512cd677bd9a9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Avicenna Journal of Phytomedicine, Vol 2, Iss 1, Pp 46-51 (2011)","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doaj.org/article/c99b87a9a47b4e598e5512cd677bd9a9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065788070","display_name":"Karim Dolati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165560825","display_name":"Mashhad University of Medical Sciences","ror":"https://ror.org/04sfka033","country_code":"IR","type":"education","lineage":["https://openalex.org/I165560825"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Karim Dolati","raw_affiliation_strings":["Pharmacological Research Center of Medicinal Plants and Department of Pharmacology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I. R. Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacological Research Center of Medicinal Plants and Department of Pharmacology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I. R. Iran","institution_ids":["https://openalex.org/I165560825"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017311650","display_name":"Hassan Rakhshandeh","orcid":"https://orcid.org/0000-0002-2118-1096","observed_orcids":["https://orcid.org/0000-0002-2118-1096"]},"institutions":[{"id":"https://openalex.org/I165560825","display_name":"Mashhad University of Medical Sciences","ror":"https://ror.org/04sfka033","country_code":"IR","type":"education","lineage":["https://openalex.org/I165560825"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Hassan Rakhshandeh","raw_affiliation_strings":["Pharmacological Research Center of Medicinal Plants and Department of Pharmacology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I. R. Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacological Research Center of Medicinal Plants and Department of Pharmacology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I. R. Iran","institution_ids":["https://openalex.org/I165560825"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085116378","display_name":"Mohammad Naser Shafei","orcid":"https://orcid.org/0000-0001-5148-9895","observed_orcids":["https://orcid.org/0000-0001-5148-9895"]},"institutions":[{"id":"https://openalex.org/I165560825","display_name":"Mashhad University of Medical Sciences","ror":"https://ror.org/04sfka033","country_code":"IR","type":"education","lineage":["https://openalex.org/I165560825"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Naser Shafei","raw_affiliation_strings":["Neuroscience Research Center and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I. R. Iran","Neuroscience Research Center and Department of Physiology, School of Medicine, Mashhad#N#University of Medical Sciences, Mashhad, I. R. Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroscience Research Center and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I. R. Iran","institution_ids":["https://openalex.org/I165560825"]},{"raw_affiliation_string":"Neuroscience Research Center and Department of Physiology, School of Medicine, Mashhad#N#University of Medical Sciences, Mashhad, I. R. Iran","institution_ids":["https://openalex.org/I165560825"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I165560825"],"apc_list":null,"apc_paid":null,"fwci":1.9915,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.88041927,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13090","display_name":"Medicinal Plant Extracts Effects","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13090","display_name":"Medicinal Plant Extracts Effects","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13651","display_name":"Medicinal Plants and Bioactive Compounds","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12891","display_name":"Medicinal Plants and Neuroprotection","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rosa-damascena","display_name":"Rosa damascena","score":1.0},{"id":"https://openalex.org/keywords/ethanol-extract","display_name":"ethanol extract","score":0.7820000052452087},{"id":"https://openalex.org/keywords/antidepressant-effects","display_name":"antidepressant effects","score":0.9810000061988831},{"id":"https://openalex.org/keywords/forced-swim-test","display_name":"forced swim test","score":0.9729999899864197},{"id":"https://openalex.org/keywords/immobility-time","display_name":"immobility time","score":0.9399999976158142},{"id":"https://openalex.org/keywords/imipramine","display_name":"imipramine","score":0.8510000109672546},{"id":"https://openalex.org/keywords/central-nervous-system-depression","display_name":"central nervous system depression","score":0.9139999747276306},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.8019999861717224},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.9610000252723694}],"concepts":[{"id":"https://openalex.org/C2775907625","wikidata":"https://www.wikidata.org/wiki/Q578904","display_name":"Rosa \u00d7 damascena","level":3,"score":0.9586582183837891},{"id":"https://openalex.org/C136569192","wikidata":"https://www.wikidata.org/wiki/Q4880745","display_name":"Behavioural despair test","level":4,"score":0.7273548245429993},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.6606187224388123},{"id":"https://openalex.org/C2779177272","wikidata":"https://www.wikidata.org/wiki/Q76560","display_name":"Antidepressant","level":3,"score":0.3693804144859314},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31252366304397583},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.2978976368904114},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14213338494300842},{"id":"https://openalex.org/C2777278459","wikidata":"https://www.wikidata.org/wiki/Q170885","display_name":"Essential oil","level":2,"score":0.08889251947402954},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.0},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:doaj.org/article:c99b87a9a47b4e598e5512cd677bd9a9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c99b87a9a47b4e598e5512cd677bd9a9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Avicenna Journal of Phytomedicine, Vol 2, Iss 1, Pp 46-51 (2011)","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:doaj.org/article:c99b87a9a47b4e598e5512cd677bd9a9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c99b87a9a47b4e598e5512cd677bd9a9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Avicenna Journal of Phytomedicine, Vol 2, Iss 1, Pp 46-51 (2011)","raw_type":"article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1965027767","https://openalex.org/W1966601183","https://openalex.org/W1970213404","https://openalex.org/W1988704615","https://openalex.org/W1990646467","https://openalex.org/W2045035877","https://openalex.org/W2045990712","https://openalex.org/W2089299823","https://openalex.org/W2092843998","https://openalex.org/W2096906953","https://openalex.org/W2103997793","https://openalex.org/W2111464609","https://openalex.org/W2111730487","https://openalex.org/W2149068465","https://openalex.org/W2172060096","https://openalex.org/W2183103147","https://openalex.org/W2185528689","https://openalex.org/W2197078876","https://openalex.org/W2249455400","https://openalex.org/W2266162021","https://openalex.org/W2302736891","https://openalex.org/W2513475888","https://openalex.org/W2589770645","https://openalex.org/W2591258244"],"related_works":["https://openalex.org/W2096906953","https://openalex.org/W2523230601","https://openalex.org/W4404008927","https://openalex.org/W6980620025","https://openalex.org/W7132921313","https://openalex.org/W2266162021","https://openalex.org/W2182590018","https://openalex.org/W2419117669","https://openalex.org/W1615835300","https://openalex.org/W2249455400"],"abstract_inverted_index":{"Objective:":[0],"Rosa":[1],"damascena":[2,39],"mill":[3],"L":[4],"(R.":[5],"damascena)":[6],"is":[7,159],"a":[8],"medicinal":[9],"plant":[10],"mostly":[11],"known":[12],"in":[13,81,135],"the":[14,82,105],"world":[15],"for":[16],"its":[17],"perfume.":[18],"It":[19],"also":[20],"has":[21],"beneficial":[22],"effects":[23],"on":[24],"stress,":[25],"tension":[26],"and":[27,48,56,74,79,100,114,121],"depression.":[28],"In":[29,154],"this":[30,136,151],"experiment":[31],"antidepressant":[32,133,145,157],"effect":[33,134,152,158,164],"of":[34,37,89,92,111,165,168],"ethanolic":[35,52,126,140,166],"extract":[36,53,93,112,127,141,167],"R.":[38,169],"by":[40,161],"forced":[41],"swimming":[42,75,99,123],"test":[43],"(FST)":[44],"was":[45],"evaluated.":[46],"Material":[47],"Methods:":[49],"Animals":[50],"received":[51],"(15,":[54],"60":[55],"90":[57,115],"mg/kg,":[58],"i.p),":[59],"imipramine":[60],"(15mg/kg,":[61],"i.p;":[62],"positive":[63],"control),":[64],"or":[65],"saline":[66],"(negative":[67],"control).":[68],"Thirty":[69],"min":[70],"post-":[71],"injection,":[72],"immobility":[73,101,119],"times":[76,102],"were":[77],"measured":[78],"compared":[80,103],"different":[83],"studied":[84],"groups.":[85],"Results:":[86],"Intraperitoneal":[87],"injection":[88],"lower":[90],"concentration":[91],"(15":[94],"mg/kg)":[95,116],"did":[96,142],"not":[97,143],"change":[98],"to":[104],"control":[106],"group.":[107],"The":[108],"higher":[109],"concentrations":[110],"(60":[113],"significantly":[117],"increased":[118],"time":[120],"decreased":[122],"time.":[124],"Therefore":[125],"at":[128],"tested":[129],"doses":[130],"had":[131],"no":[132],"study.":[137],"Conclusion:":[138],"Although":[139],"have":[144],"effect,":[146],"we":[147],"cannot":[148],"rule":[149],"out":[150],"altogether.":[153],"our":[155],"opinion,":[156],"masked":[160],"CNS":[162],"depression":[163],"damascena.":[170]},"counts_by_year":[{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}