{"id":"https://openalex.org/W1927701703","doi":null,"title":"Corticosteroids can reverse severe imatinib-induced hepatotoxicity.","display_name":"Corticosteroids can reverse severe imatinib-induced hepatotoxicity.","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W1927701703","mag":"1927701703","pmid":"https://pubmed.ncbi.nlm.nih.gov/16434374"},"language":"en","primary_location":{"id":"pmid:16434374","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16434374","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haematologica","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2318/32002","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079082437","display_name":"Per T Ljungman","orcid":"https://orcid.org/0000-0002-8281-3245","observed_orcids":["https://orcid.org/0000-0002-8281-3245"]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT","SE"],"is_corresponding":false,"raw_author_name":"Per Ljungman","raw_affiliation_strings":["Hematology Center, Karolinska University Hospital, SE-14186 Stockholm, Sweden. Per.Ljungman@medhs.ki.se","Divisione di Ematologia dell'Universit\u00e0 degli Studi di Torino, Molinette Hospital, Turin, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology Center, Karolinska University Hospital, SE-14186 Stockholm, Sweden. Per.Ljungman@medhs.ki.se","institution_ids":["https://openalex.org/I1335113835"]},{"raw_affiliation_string":"Divisione di Ematologia dell'Universit\u00e0 degli Studi di Torino, Molinette Hospital, Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lena Perez-Bercoff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lena Perez-Bercoff","raw_affiliation_strings":["University of Turin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Turin","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jerker Jonsson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Jerker Jonsson","raw_affiliation_strings":["University of Turin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Turin","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Gayane Avetisyan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gayane Avetisyan","raw_affiliation_strings":["University of Turin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Turin","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Elda Sparrelid","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elda Sparrelid","raw_affiliation_strings":["University of Turin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Turin","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065745451","display_name":"JOHAN ASCHAN","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Johan Aschan","raw_affiliation_strings":["University of Turin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Turin","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lisbeth Barkholt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lisbeth Barkholt","raw_affiliation_strings":["University of Turin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Turin","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kajsa Larsson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Kajsa Larsson","raw_affiliation_strings":["University of Turin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Turin","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jacek Winiarski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2803066834","display_name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico","ror":"https://ror.org/016zn0y21","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I189158943","https://openalex.org/I2803066834","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Jacek Winiarski","raw_affiliation_strings":["Fondazione IRCCS C\u00e1 Granda-Ospedale Maggiore Policlinico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione IRCCS C\u00e1 Granda-Ospedale Maggiore Policlinico","institution_ids":["https://openalex.org/I2803066834"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhibing Yun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Zhibing Yun","raw_affiliation_strings":["University of Turin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Turin","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003097876","display_name":"Olle T.H. Ringd\u00e9n","orcid":"https://orcid.org/0000-0002-6092-1536","observed_orcids":["https://orcid.org/0000-0002-6092-1536"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Olle Ringd\u00e9n","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":10.7896,"has_fulltext":true,"cited_by_count":245,"citation_normalized_percentile":{"value":0.98848921,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"91","issue":"1","first_page":"78","last_page":"83"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.6586999893188477,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.6586999893188477,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.2549000084400177,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.03020000085234642,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/imatinib","display_name":"imatinib","score":0.7149999737739563},{"id":"https://openalex.org/keywords/hepatotoxicity","display_name":"hepatotoxicity","score":0.9589999914169312},{"id":"https://openalex.org/keywords/corticosteroids","display_name":"corticosteroids","score":0.9589999914169312},{"id":"https://openalex.org/keywords/cytomegalovirus-disease","display_name":"cytomegalovirus disease","score":0.8429999947547913},{"id":"https://openalex.org/keywords/allogeneic-stem-cell-transplantation","display_name":"allogeneic stem cell transplantation","score":0.9660000205039978},{"id":"https://openalex.org/keywords/preemptive-antiviral-therapy","display_name":"preemptive antiviral therapy","score":0.859000027179718},{"id":"https://openalex.org/keywords/acute-graft-versus-host-disease","display_name":"acute graft-versus-host disease","score":0.9020000100135803},{"id":"https://openalex.org/keywords/cytomegalovirus-serostatus","display_name":"CMV serostatus","score":0.7360000014305115},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.6949999928474426}],"concepts":[{"id":"https://openalex.org/C2777583451","wikidata":"https://www.wikidata.org/wiki/Q177094","display_name":"Imatinib","level":3,"score":0.9082319736480713},{"id":"https://openalex.org/C2778715236","wikidata":"https://www.wikidata.org/wiki/Q55622662","display_name":"Discontinuation","level":2,"score":0.9057594537734985},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8580516576766968},{"id":"https://openalex.org/C2778720950","wikidata":"https://www.wikidata.org/wiki/Q424972","display_name":"Prednisone","level":2,"score":0.7497351765632629},{"id":"https://openalex.org/C2776804153","wikidata":"https://www.wikidata.org/wiki/Q210420","display_name":"Corticosteroid","level":2,"score":0.6483430862426758},{"id":"https://openalex.org/C2780372218","wikidata":"https://www.wikidata.org/wiki/Q417222","display_name":"Methylprednisolone","level":2,"score":0.5962175726890564},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.5822477340698242},{"id":"https://openalex.org/C2776960273","wikidata":"https://www.wikidata.org/wiki/Q729735","display_name":"Chronic myelogenous leukemia","level":3,"score":0.4996218681335449},{"id":"https://openalex.org/C2993709057","wikidata":"https://www.wikidata.org/wiki/Q1349821","display_name":"Liver toxicity","level":3,"score":0.4736569821834564},{"id":"https://openalex.org/C3019892230","wikidata":"https://www.wikidata.org/wiki/Q177094","display_name":"Imatinib mesylate","level":4,"score":0.4501382112503052},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.40319642424583435},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38750946521759033},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3845703601837158},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.32224327325820923},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.2151186168193817},{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003586","descriptor_name":"Cytomegalovirus Infections","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009894","descriptor_name":"Opportunistic Infections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011292","descriptor_name":"Premedication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014184","descriptor_name":"Transplantation, Homologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018380","descriptor_name":"Hematopoietic Stem Cell Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"pmid:16434374","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16434374","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haematologica","raw_type":"Journal Article"},{"id":"pmid:16785130","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16785130","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haematologica","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unito.it:2318/32002","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2318/32002","pdf_url":"http://hdl.handle.net/2318/32002","source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:boa.unimib.it:10281/15066","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10281/15066","pdf_url":null,"source":{"id":"https://openalex.org/S4306401259","display_name":"BOA (University of Milano-Bicocca)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I66752286","host_organization_name":"University of Milano-Bicocca","host_organization_lineage":["https://openalex.org/I66752286"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:5d505ea83147458c84e8bb95fd789751","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/5d505ea83147458c84e8bb95fd789751","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Haematologica, Vol 91, Iss 1 (2006)","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:815481c64607450cb979fc86f23b5883","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/815481c64607450cb979fc86f23b5883","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Haematologica, Vol 91, Iss 6_Suppl (2006)","raw_type":"article"},{"id":"mag:1927701703","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16785130","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:iris.unito.it:2318/32002","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2318/32002","pdf_url":"http://hdl.handle.net/2318/32002","source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1927701703.pdf","grobid_xml":"https://content.openalex.org/works/W1927701703.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W66769540","https://openalex.org/W1492949707","https://openalex.org/W1564109452","https://openalex.org/W1568041502","https://openalex.org/W1955863325","https://openalex.org/W1967773734","https://openalex.org/W1978288530","https://openalex.org/W1981792827","https://openalex.org/W2013103929","https://openalex.org/W2019248811","https://openalex.org/W2026318747","https://openalex.org/W2030154801","https://openalex.org/W2048316650","https://openalex.org/W2064796142","https://openalex.org/W2072986862","https://openalex.org/W2076919967","https://openalex.org/W2080607847","https://openalex.org/W2083141369","https://openalex.org/W2090071556","https://openalex.org/W2096233660","https://openalex.org/W2102012621","https://openalex.org/W2112067138","https://openalex.org/W2112300621","https://openalex.org/W2119627739","https://openalex.org/W2136013587","https://openalex.org/W2164143794","https://openalex.org/W2168902747","https://openalex.org/W2169086958","https://openalex.org/W2171889269","https://openalex.org/W2268091496","https://openalex.org/W2315851568","https://openalex.org/W2395504431","https://openalex.org/W2411118847"],"related_works":["https://openalex.org/W7099831045","https://openalex.org/W2276136877","https://openalex.org/W4405037757","https://openalex.org/W2495567319","https://openalex.org/W1978481681","https://openalex.org/W2192795845","https://openalex.org/W2331638532","https://openalex.org/W2338966449","https://openalex.org/W4385227063","https://openalex.org/W2047744247"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1,37,219],"OBJECTIVES:":[2],"Cytomegalovirus":[3],"(CMV)":[4],"disease":[5,109,133,139,161],"remains":[6],"an":[7,230],"important":[8,231],"complication":[9],"of":[10,33,54,72,91,107,191,199,215,236],"allogeneic":[11],"stem":[12],"cell":[13],"transplantation":[14],"(SCT).":[15],"We":[16,39],"studied":[17,40],"viral":[18,24,79,102,124,202,224],"load":[19,25,125,203,225],"kinetics":[20],"and":[21,26,85,94,115,165,196],"correlated":[22],"the":[23,31,73,92,101,197],"other":[27],"transplant":[28],"factors":[29,179,211],"with":[30],"development":[32,214,235],"CMV":[34,46,50,55,65,108,132,138,181,216,237],"disease.":[35,182,217,238],"DESIGN":[36],"METHODS:":[38],"162":[41,74],"consecutive":[42],"patients":[43,129,136,184],"who":[44,130,185],"were":[45,81,126,176,208],"seropositive":[47,51],"or":[48],"had":[49],"donors.":[52],"Quantification":[53],"DNA":[56,66],"was":[57,68,110],"performed":[58],"by":[59],"real-time":[60],"polymerase":[61],"chain":[62],"reaction.":[63],"RESULTS:":[64],"detected":[67,69],"in":[70,128,135,155,201,223],"105":[71],"patients.":[75],"The":[76,88,104,122],"mean":[77],"peak":[78,123],"loads":[80],"similar":[82],"at":[83,112,117],"first":[84,205],"subsequent":[86,213],"reactivations.":[87],"serologic":[89],"status":[90],"donors":[93],"recipients":[95],"prior":[96],"to":[97,172],"SCT":[98],"significantly":[99],"influenced":[100],"load.":[103],"cumulative":[105],"incidence":[106],"1.8%":[111],"100":[113],"days":[114,119],"6.3%":[116],"365":[118],"after":[120],"SCT.":[121],"higher":[127],"developed":[131],"than":[134,188],"without":[137],"(log10":[140],"3.5;":[141],"SE":[142,149],"+/-":[143,150],"0.26/200,000":[144],"cells":[145],"vs.":[146],"log10":[147],"2.7;":[148],"0.09/200,000":[151],"cells;":[152],"p=0.02).":[153],"However,":[154],"multivariate":[156],"analysis,":[157],"only":[158],"acute":[159,194],"graft-versus-host":[160],"(GVHD)":[162],"grade":[163],"II-IV":[164],"a":[166,169,173],"graft":[167],"from":[168],"CMV-negative":[170],"donor":[171],"CMV-positive":[174],"patient":[175],"significant":[177,209],"risk":[178,210],"for":[180,212,233],"In":[183],"required":[186],"more":[187],"one":[189],"course":[190],"pre-emptive":[192,206,227],"therapy,":[193],"GVHD":[195],"rate":[198],"decrease":[200,222],"during":[204,226],"therapy":[207,228],"INTERPRETATION":[218],"CONCLUSIONS:":[220],"A":[221],"is":[229],"factor":[232],"later":[234]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":18},{"year":2019,"cited_by_count":15},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":19},{"year":2015,"cited_by_count":17},{"year":2014,"cited_by_count":14},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":11}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2016-06-24T00:00:00"}