{"id":"https://openalex.org/W1922639452","doi":null,"title":"Expression of the Rhizopus oryzae lipase in Pichia pastoris under the control of the FLD1 promoter","display_name":"Expression of the Rhizopus oryzae lipase in Pichia pastoris under the control of the FLD1 promoter","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W1922639452","mag":"1922639452"},"language":"en","primary_location":{"id":"pmh:oai:ddd.uab.cat:37600","doi":null,"is_oa":true,"landing_page_url":"https://ddd.uab.cat/record/37600","pdf_url":"https://ddd.uab.cat/pub/tesis/2006/tdx-0412107-155334/drr1de1.pdf","source":{"id":"https://openalex.org/S4306400380","display_name":"Dip\u00f2sit Digital de Documents de la UAB (Universitat Aut\u00f2noma de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I123044942","host_organization_name":"Universitat Aut\u00f2noma de Barcelona","host_organization_lineage":["https://openalex.org/I123044942"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Tesi doctoral"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ddd.uab.cat/pub/tesis/2006/tdx-0412107-155334/drr1de1.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025472654","display_name":"David Resina","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"David Resina Rodr\u00edguez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5025472654"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9702000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9702000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.026200000196695328,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rhizopus-oryzae-lipase","display_name":"Rhizopus oryzae lipase","score":0.9909999966621399},{"id":"https://openalex.org/keywords/recombinant-protein-expression","display_name":"recombinant protein expression","score":0.8119999766349792},{"id":"https://openalex.org/keywords/komagataella-phaffii","display_name":"Pichia pastoris","score":0.9890000224113464},{"id":"https://openalex.org/keywords/semi-continuous-culture","display_name":"semi-continuous culture","score":0.7139999866485596},{"id":"https://openalex.org/keywords/specific-growth-rate","display_name":"specific growth rate","score":0.621999979019165},{"id":"https://openalex.org/keywords/unfolded-protein-response","display_name":"unfolded protein response","score":0.8059999942779541},{"id":"https://openalex.org/keywords/bip","display_name":"BiP","score":0.7820000052452087}],"concepts":[{"id":"https://openalex.org/C2781372317","wikidata":"https://www.wikidata.org/wiki/Q148697","display_name":"Pichia pastoris","level":4,"score":0.9646722078323364},{"id":"https://openalex.org/C2778541762","wikidata":"https://www.wikidata.org/wiki/Q3024179","display_name":"Rhizopus oryzae","level":3,"score":0.9325164556503296},{"id":"https://openalex.org/C2779697368","wikidata":"https://www.wikidata.org/wiki/Q380967","display_name":"Lipase","level":3,"score":0.8966031074523926},{"id":"https://openalex.org/C2778753027","wikidata":"https://www.wikidata.org/wiki/Q134258","display_name":"Rhizopus","level":3,"score":0.5662602782249451},{"id":"https://openalex.org/C2779703480","wikidata":"https://www.wikidata.org/wiki/Q125153","display_name":"Pichia","level":5,"score":0.48642683029174805},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38385602831840515},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.3651495575904846},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.30246955156326294},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.24328097701072693},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23220029473304749},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22615310549736023},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.17667174339294434},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.15032514929771423}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:ddd.uab.cat:37600","doi":null,"is_oa":true,"landing_page_url":"https://ddd.uab.cat/record/37600","pdf_url":"https://ddd.uab.cat/pub/tesis/2006/tdx-0412107-155334/drr1de1.pdf","source":{"id":"https://openalex.org/S4306400380","display_name":"Dip\u00f2sit Digital de Documents de la UAB (Universitat Aut\u00f2noma de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I123044942","host_organization_name":"Universitat Aut\u00f2noma de Barcelona","host_organization_lineage":["https://openalex.org/I123044942"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Tesi doctoral"},{"id":"pmh:oai:www.tdx.cat:10803/5308","doi":null,"is_oa":true,"landing_page_url":"http://www.tdx.cat/TDX-0412107-155334","pdf_url":"http://www.tdx.cat/TDX-0412107-155334","source":{"id":"https://openalex.org/S4306401111","display_name":"Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:dnet:tdr_________::2ca3a4d2bb0269ff1e11aaca3c320fa0","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10803/5308","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:dnet:uabarcelona_::e09579fd1e3f6cab1b89625c619755f2","doi":null,"is_oa":false,"landing_page_url":"http://ddd.uab.cat/record/37600","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:1922639452","doi":null,"is_oa":false,"landing_page_url":"https://ddd.uab.cat/pub/tesis/2006/tdx-0412107-155334/drr1de1.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306531624","display_name":"TDX (Tesis Doctorals en Xarxa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":null}],"best_oa_location":{"id":"pmh:oai:ddd.uab.cat:37600","doi":null,"is_oa":true,"landing_page_url":"https://ddd.uab.cat/record/37600","pdf_url":"https://ddd.uab.cat/pub/tesis/2006/tdx-0412107-155334/drr1de1.pdf","source":{"id":"https://openalex.org/S4306400380","display_name":"Dip\u00f2sit Digital de Documents de la UAB (Universitat Aut\u00f2noma de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I123044942","host_organization_name":"Universitat Aut\u00f2noma de Barcelona","host_organization_lineage":["https://openalex.org/I123044942"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Tesi doctoral"},"sustainable_development_goals":[{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.6735000014305115}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1922639452.pdf","grobid_xml":"https://content.openalex.org/works/W1922639452.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W52050120","https://openalex.org/W315837935","https://openalex.org/W1480799853","https://openalex.org/W1519297291","https://openalex.org/W1609148190","https://openalex.org/W1696872742","https://openalex.org/W1969115506","https://openalex.org/W1970228759","https://openalex.org/W1970780221","https://openalex.org/W1972668501","https://openalex.org/W1986376155","https://openalex.org/W1991245779","https://openalex.org/W1994348237","https://openalex.org/W1997002995","https://openalex.org/W2005145242","https://openalex.org/W2005619516","https://openalex.org/W2005784337","https://openalex.org/W2007132819","https://openalex.org/W2014736760","https://openalex.org/W2016708899","https://openalex.org/W2020437934","https://openalex.org/W2024589425","https://openalex.org/W2026349284","https://openalex.org/W2030239671","https://openalex.org/W2031817951","https://openalex.org/W2032988631","https://openalex.org/W2038756774","https://openalex.org/W2048001750","https://openalex.org/W2063554961","https://openalex.org/W2063563712","https://openalex.org/W2071768512","https://openalex.org/W2071890783","https://openalex.org/W2089999523","https://openalex.org/W2098665480","https://openalex.org/W2100057937","https://openalex.org/W2107238882","https://openalex.org/W2108786034","https://openalex.org/W2110069686","https://openalex.org/W2115137627","https://openalex.org/W2116516740","https://openalex.org/W2117753413","https://openalex.org/W2117935503","https://openalex.org/W2118542368","https://openalex.org/W2131510511","https://openalex.org/W2133112227","https://openalex.org/W2134653155","https://openalex.org/W2137056661","https://openalex.org/W2137755719","https://openalex.org/W2147923184","https://openalex.org/W2148009678","https://openalex.org/W2150699248","https://openalex.org/W2152455126","https://openalex.org/W2156283030","https://openalex.org/W2169442097","https://openalex.org/W2170298918"],"related_works":["https://openalex.org/W2097542486","https://openalex.org/W2063070929","https://openalex.org/W2005784337","https://openalex.org/W2156592548","https://openalex.org/W7058180460","https://openalex.org/W1990493339","https://openalex.org/W2157368629","https://openalex.org/W1992047914","https://openalex.org/W2791677896","https://openalex.org/W6983543837"],"abstract_inverted_index":{"Durant":[0],"el":[1,22,51,57,89,353,363,375,392,417,527,531,548,619,628,719],"curs":[2],"d'aquest":[3,446],"treball":[4],"s'han":[5],"realitzat":[6,180],"l'expressi\u00f3":[7,239,597],"de":[8,11,31,36,53,95,100,115,131,143,159,172,189,205,209,220,228,240,247,260,271,284,299,320,327,339,351,357,386,412,437,455,464,476,488,490,493,496,505,509,533,539,572,583,598,608,621,629,643,646,673,683,698,701,709,727],"la":[9,44,54,82,104,186,225,229,248,265,269,289,300,318,395,426,429,438,453,456,513,517,522,534,554,563,601,610,622,630,644,666,677,684,699,722],"lipasa":[10],"Rhizopus":[12],"oryzae":[13],"(ROL)":[14],"sota":[15],"en":[16,21,33,71,73,117,133,317,382,470,473,553,580,638,731],"control":[17,656],"del":[18,79,359,507,616,654,724,733],"promotor":[19,58,90,734],"FLD1":[20,735],"llevat":[23],"Pichia":[24],"pastoris":[25,341,615,729],"i":[26,56,81,138,145,165,222,224,286,322,333,394,530,562,707,721],"s'ha":[27],"desenvolupat":[28],"una":[29,109,129,296,306,402,422,695],"estrat\u00e8gia":[30,130,307],"cultiu":[32,132,179,655],"semi-discontinu":[34,134],"lliure":[35],"metanol.":[37],"En":[38,123,636],"primer":[39],"lloc":[40,125],"es":[41,126,175,195,242,254,330,405,480,500,543,624,662,679,692],"va":[42,62,127,176,196,263,294,304,331,406,441,448,468,481,574,625,663,693],"realitzar":[43,407],"construcci\u00f3":[45],"d'un":[46,668],"vector":[47,61],"d'expressi\u00f3":[48,385,642,726],"que":[49,372,467,596,665],"cont\u00e9":[50],"gen":[52,325,345,376,415,447,508,532,620],"ROL":[55,287,477,599,623],"FLD1.":[59,91],"Aquest":[60,715],"ser":[63,108,442,576,649],"subseq\u00fcentment":[64],"transformat":[65],"a":[66,85,98,119,141,151,155,181,191,200,203,231,336,409,421,425,452,483,588,603,613,704,737],"P.":[67,340,497,614,674,728],"pastoris.":[68,498],"Els":[69,365,537],"cultius":[70,118,154,194,293,368,637],"discontinu":[72,639],"bioreactor":[74],"van":[75,149,243,255,378,501,544,592,648],"revelar":[76],"l'efecte":[77,389],"sin\u00e8rgic":[78],"metanol":[80,116],"metilamina":[83,139],"com":[84,97,140,736],"substrats":[86],"inductors":[87],"sobre":[88,391,559],"A":[92,660],"m\u00e9s,":[93,589,661],"l'\u00fas":[94,114,732],"sorbitol":[96,137],"font":[99],"carboni,":[101],"combinat":[102],"amb":[103,268,362,369,606,627,712],"metilamina,":[105],"ha":[106,717],"resultat":[107],"combinaci\u00f3":[110],"atractiva":[111],"per":[112,233,273,310,348,408,420],"evitar":[113],"altes":[120],"densitats":[121],"cel\u00b7lulars.":[122],"segon":[124],"desenvolupar":[128],"fent":[135,546],"servir":[136,547],"fonts":[142],"carboni":[144],"nitrogen":[146],"respectivament.":[147],"Es":[148,262,303],"dur":[150,482],"terme":[152,484],"tres":[153,193],"diferents":[156],"velocitats":[157],"espec\u00edfiques":[158],"creixement,":[160],"0.005":[161],"h-1,":[162,164],"0.01":[163],"0.02":[166,182],"h-1.":[167,183],"El":[168,279,324,344,414],"nivell":[169,246],"m\u00e9s":[170,460],"alt":[171],"prote\u00efna":[173,535,645,700],"recombinant":[174],"obtenir":[177],"al":[178,218,462,671,681,686,739],"Malgrat":[184],"aix\u00f2":[185],"velocitat":[187,570],"espec\u00edfica":[188,556,571],"producci\u00f3":[190,573],"tots":[192],"disminuir":[197],"despr\u00e9s":[198],"d'arribar":[199],"un":[201,349,380,450,471,577],"m\u00e0xim":[202],"prop":[204],"les":[206,337,370],"30":[207],"hores":[208],"cultiu.":[210],"Per":[211,399,689],"tal":[212,311],"d'analitzar":[213],"els":[214,245,257,275,313,383,432,435,474,503,581,590,640],"potencials":[215],"colls":[216,315],"d'ampolla":[217,316],"proc\u00e9s":[219],"plegament":[221,321,393],"secreci\u00f3,":[223],"possible":[226,297],"activaci\u00f3":[227,298],"resposta":[230,301,602],"estres":[232],"prote\u00efnes":[234],"mal":[235],"plegades":[236],"(UPR)":[237],"durant":[238,288],"ROL,":[241,387],"analitzar":[244,256,274],"xaperona":[249],"BiP,":[250],"indicativa":[251],"d'estres.":[252,302],"Tamb\u00e9":[253,479],"nivells":[258,276,282,384,475,487,504,538,582,641],"intracel\u00b7lulars":[259,283],"ROL.":[261,343,536,659],"utilitzar":[264],"immunofluoresc\u00e8ncia,":[266],"combinada":[267],"citometria":[270],"flux":[272],"d'aquestes":[277],"prote\u00efnes.":[278],"increment":[280,381,472],"dels":[281,292,367,486,557,585],"BiP":[285,524],"fase":[290],"d'inducci\u00f3":[291],"indicar":[295],"proposar":[305],"d'enginyeria":[308],"metab\u00f2lica":[309],"alleujar":[312],"possibles":[314],"via":[319],"secreci\u00f3.":[323,413],"HAC1":[326,346,377],"Saccaromyces":[328],"cerevisiae":[329],"clonar":[332],"expressar":[334],"constitutivament":[335,374],"c\u00e8l\u00b7lules":[338],"co-expressant":[342],"codifica":[347,419],"factor":[350,578],"transcripci\u00f3":[352,489,506,540,584],"qual":[354,418,430],"\u00e9s":[355],"responsable":[356],"l'activaci\u00f3":[358],"gens":[360,492,542,586],"relacionats":[361],"UPR.":[364],"resultats":[366,591],"soques":[371],"expressen":[373],"mostrar":[379],"demostrant":[388],"positiu":[390],"secreci\u00f3":[396],"d'aquesta":[397],"modificaci\u00f3.":[398],"altra":[400,690],"banda,":[401],"segona":[403],"modificaci\u00f3":[404],"millorar":[410],"l'efici\u00e8ncia":[411],"GAS1,":[416],"glycoprote\u00efna":[423],"ancorada":[424],"membrana":[427],"plasm\u00e0tica":[428],"realitza":[431],"unions":[433],"entre":[434],"?-glucans":[436],"paret":[439,457],"cel\u00b7lular":[440],"disruptat.":[443],"La":[444,569],"deleci\u00f3":[445],"provocar":[449],"canvi":[451],"conformaci\u00f3":[454],"cel\u00b7lular,":[458],"fent-la":[459],"permeable":[461],"pas":[463],"prote\u00efnes,":[465],"fet":[466],"resultar":[469,575],"extracel\u00b7lular.":[478,688],"l'estudi":[485],"determinats":[491],"d'inter\u00e8s":[494],"rellevant":[495],"Concretament":[499],"quantificar":[502,545],"l'alcohol":[510],"oxidasa":[511],"(AOX1),":[512],"formaldehid":[514],"deshidrogenase":[515],"(FLD1),":[516],"protein":[518,633],"disulfide":[519],"isomerase":[520],"(PDI),":[521],"proteina":[523],"(gen":[525],"KAR2),":[526],"26S":[528],"rRNA,":[529],"d'aquests":[541],"sandwich":[549],"hybridization":[550],"assay":[551],"basat":[552],"immobilitzaci\u00f3":[555],"mRNAs":[558],"esferes":[560],"magn\u00e8tiques":[561],"seva":[564],"posterior":[565],"detecci\u00f3":[566],"mitjan\u00e7ant":[567],"fluorimetria.":[568],"clau":[579],"analitzats;":[587],"aportar":[593],"noves":[594],"evidencies":[595],"activa":[600],"estres.":[604],"Finalment,":[605],"l'objectiu":[607],"determinar":[609],"localitzaci\u00f3":[611],"intracel\u00b7lular":[612,697],"producte":[617,669],"recombinant,":[618],"fusionar":[626],"green":[631],"fluorescent":[632],"d'Aequorea":[634],"victoria.":[635],"fusi\u00f3":[647,702],"deu":[650],"vegades":[651],"inferiors":[652],"als":[653],"expressant":[657],"solament":[658],"observar":[664,694],"fluoresc\u00e8ncia":[667],"associat":[670],"creixement":[672],"pastoris,":[675],"probablement":[676],"riboflavina,":[678],"superposava":[680],"senyal":[682],"GFP":[685],"medi":[687],"banda":[691],"acumulaci\u00f3":[696],"localitzada":[703],"l'espai":[705],"periplasm\u00e0tic":[706],"dins":[708],"compartiments":[710],"cel\u00b7lulars":[711],"aparen\u00e7a":[713],"vacuolar.":[714],"estudi":[716],"perm\u00e8s":[718],"desenvolupament":[720],"millora":[723],"sistema":[725],"basant-se":[730],"alternativa":[738],"cl\u00e0ssic":[740],"AOX1.":[741]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}