{"id":"https://openalex.org/W1921988695","doi":"https://doi.org/10.1002/jsfa.6893","title":"Development of new reference material neohesperidin for quality control of dietary supplements","display_name":"Development of new reference material neohesperidin for quality control of dietary supplements","publication_year":2014,"publication_date":"2014-08-29","ids":{"openalex":"https://openalex.org/W1921988695","doi":"https://doi.org/10.1002/jsfa.6893","mag":"1921988695","pmid":"https://pubmed.ncbi.nlm.nih.gov/25170574"},"language":"en","primary_location":{"id":"doi:10.1002/jsfa.6893","doi":"https://doi.org/10.1002/jsfa.6893","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jsfa.6893","pdf_url":null,"source":{"id":"https://openalex.org/S206298197","display_name":"Journal of the Science of Food and Agriculture","issn_l":"0022-5142","issn":["0022-5142","1097-0010"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Science of Food and Agriculture","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054169053","display_name":"Ningbo Gong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ningbo Gong","raw_affiliation_strings":["Beijing Key Laboratory of Polymorphic Drugs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Polymorphic Drugs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050 China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091598985","display_name":"Baoxi Zhang","orcid":"https://orcid.org/0000-0001-7462-7592","observed_orcids":["https://orcid.org/0000-0001-7462-7592"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Baoxi Zhang","raw_affiliation_strings":["Beijing Key Laboratory of Polymorphic Drugs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Polymorphic Drugs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050 China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009377338","display_name":"Dezhi Yang","orcid":"https://orcid.org/0000-0002-3159-4126","observed_orcids":["https://orcid.org/0000-0002-3159-4126"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dezhi Yang","raw_affiliation_strings":["Beijing Key Laboratory of Polymorphic Drugs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Polymorphic Drugs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050 China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037760138","display_name":"Zhaolin Gao","orcid":"https://orcid.org/0000-0002-1647-4898","observed_orcids":["https://orcid.org/0000-0002-1647-4898"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhaolin Gao","raw_affiliation_strings":["Shandong Key laboratory of Polymorphic Drugs, Tengzhou, Shandong, 277500 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Key laboratory of Polymorphic Drugs, Tengzhou, Shandong, 277500 China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033681865","display_name":"Guanhua Du","orcid":"https://orcid.org/0000-0002-6896-0847","observed_orcids":["https://orcid.org/0000-0002-6896-0847"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guanhua Du","raw_affiliation_strings":["Beijing Key Laboratory of Drug Targets and Screening Research, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Drug Targets and Screening Research, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050 China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"last","author":{"id":null,"display_name":"Yang Lu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yang Lu","raw_affiliation_strings":["Beijing Key Laboratory of Polymorphic Drugs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050 China","Shandong Key laboratory of Polymorphic Drugs, Tengzhou, Shandong, 277500 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Polymorphic Drugs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050 China","institution_ids":["https://openalex.org/I200296433"]},{"raw_affiliation_string":"Shandong Key laboratory of Polymorphic Drugs, Tengzhou, Shandong, 277500 China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5033681865"],"corresponding_institution_ids":["https://openalex.org/I200296433"],"apc_list":{"value":4620,"currency":"USD","value_usd":4620},"apc_paid":null,"fwci":0.3252,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.68989186,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"95","issue":"9","first_page":"1885","last_page":"1891"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11890","display_name":"Scientific Measurement and Uncertainty Evaluation","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11890","display_name":"Scientific Measurement and Uncertainty Evaluation","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14127","display_name":"Food and Agricultural Sciences","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neohesperidin","display_name":"neohesperidin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/certified-reference-materials","display_name":"certified reference materials","score":0.9890000224113464},{"id":"https://openalex.org/keywords/dietary-supplements","display_name":"dietary supplements","score":0.8859999775886536},{"id":"https://openalex.org/keywords/quality-control","display_name":"quality control","score":0.9549999833106995},{"id":"https://openalex.org/keywords/flavanone-glycosides","display_name":"flavanone glycosides","score":0.9179999828338623},{"id":"https://openalex.org/keywords/citrus","display_name":"citrus","score":0.5120000243186951},{"id":"https://openalex.org/keywords/measurement-traceability","display_name":"measurement traceability","score":0.9129999876022339},{"id":"https://openalex.org/keywords/value-assignment","display_name":"value assignment","score":0.6110000014305115},{"id":"https://openalex.org/keywords/uncertainty-estimation","display_name":"uncertainty estimation","score":0.7540000081062317},{"id":"https://openalex.org/keywords/homogeneity-and-stability","display_name":"homogeneity and stability","score":0.8569999933242798},{"id":"https://openalex.org/keywords/coulometric-titration","display_name":"coulometric titration","score":0.9079999923706055},{"id":"https://openalex.org/keywords/mass-balance-method","display_name":"mass balance method","score":0.6919999718666077},{"id":"https://openalex.org/keywords/differential-scanning-calorimetry","display_name":"differential scanning calorimetry","score":0.875}],"concepts":[{"id":"https://openalex.org/C100859065","wikidata":"https://www.wikidata.org/wiki/Q906323","display_name":"Certified reference materials","level":3,"score":0.5752741694450378},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3770849108695984},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3352035880088806},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3350543975830078},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.2277216613292694},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.21488991379737854},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002138","descriptor_name":"Calibration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002152","descriptor_name":"Calorimetry, Differential Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005513","descriptor_name":"Food Inspection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006569","descriptor_name":"Hesperidin","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D006569","descriptor_name":"Hesperidin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006569","descriptor_name":"Hesperidin","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D006569","descriptor_name":"Hesperidin","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D006569","descriptor_name":"Hesperidin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011786","descriptor_name":"Quality Control","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013056","descriptor_name":"Spectrophotometry, Ultraviolet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017186","descriptor_name":"Titrimetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D035501","descriptor_name":"Uncertainty","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/jsfa.6893","doi":"https://doi.org/10.1002/jsfa.6893","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jsfa.6893","pdf_url":null,"source":{"id":"https://openalex.org/S206298197","display_name":"Journal of the Science of Food and Agriculture","issn_l":"0022-5142","issn":["0022-5142","1097-0010"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Science of Food and Agriculture","raw_type":"journal-article"},{"id":"pmid:25170574","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25170574","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the science of food and agriculture","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.40450000762939453,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1561394207","https://openalex.org/W1729853508","https://openalex.org/W1968359564","https://openalex.org/W2003312668","https://openalex.org/W2007172678","https://openalex.org/W2014996170","https://openalex.org/W2020146124","https://openalex.org/W2023841487","https://openalex.org/W2033381837","https://openalex.org/W2040211336","https://openalex.org/W2043878467","https://openalex.org/W2064275766","https://openalex.org/W2067413874","https://openalex.org/W2079355261","https://openalex.org/W2084180762","https://openalex.org/W2092538251","https://openalex.org/W2093712908","https://openalex.org/W2164562908","https://openalex.org/W2182975373","https://openalex.org/W2725197866"],"related_works":["https://openalex.org/W2082855662","https://openalex.org/W2075137268","https://openalex.org/W2796638281","https://openalex.org/W2064939945","https://openalex.org/W3037796974","https://openalex.org/W4411682392","https://openalex.org/W2093617597","https://openalex.org/W4408429113","https://openalex.org/W2990861813","https://openalex.org/W2040971708"],"abstract_inverted_index":{"BACKGROUND:":[0],"Neohesperidin":[1],"is":[2,15,122],"an":[3,127],"important":[4],"natural":[5],"flavanone":[6],"glycoside":[7],"distributed":[8],"in":[9,25,36],"several":[10],"citrus":[11],"species.":[12],"This":[13,72],"compound":[14],"widely":[16],"used":[17,164],"as":[18,176,178],"a":[19,89,150],"raw":[20],"material":[21,93,139],"for":[22,31,46,113,146],"food":[23,27],"additives":[24],"the":[26,42,52,56,75,171],"industry.":[28],"The":[29,116,137,157],"request":[30],"certified":[32,91,117],"reference":[33,92,138],"materials":[34],"(CRMs)":[35],"dietary":[37,183],"supplements":[38],"was":[39,49,142],"stipulated":[40],"by":[41,51],"National":[43],"Administrative":[44],"Committee":[45],"CRMs":[47],"and":[48,58,63,80,85,102,111,144,169,188],"underpinned":[50],"need":[53],"to":[54,64,107,165],"improve":[55,170],"accuracy":[57,172],"comparability":[59],"of":[60,68,88,94,119,130,153,160,173,181],"measurement":[61,174],"data":[62,175],"establish":[65],"metrological":[66],"traceability":[67],"analytical":[69,167],"results.":[70],"RESULTS:":[71],"paper":[73],"reports":[74],"sample":[76],"preparation":[77],"methodology,":[78],"homogeneity":[79],"stability":[81],"studies,":[82],"value":[83,118],"assignment":[84],"uncertainty":[86,129],"estimation":[87],"new":[90,158],"neohesperidin":[95,120,161],"(GBW09522).":[96],"Differential":[97],"scanning":[98],"calorimetry,":[99],"coulometric":[100],"titration":[101],"mass":[103],"balance":[104],"methods":[105,168],"proved":[106],"be":[108,163],"sufficiently":[109],"reliable":[110],"accurate":[112],"certification":[114],"purposes.":[115],"CRM":[121,159],"994":[123],"g":[124,132],"kg(-1)":[125,133],"with":[126],"expanded":[128],"4":[131],"(k":[134],"=":[135],"2).":[136],"described":[140],"above":[141],"homogeneous":[143],"stable":[145],"12":[147],"months":[148],"at":[149],"storage":[151],"temperature":[152],"25":[154],"\u00b0C.":[155],"CONCLUSION:":[156],"can":[162],"validate":[166],"well":[177],"quality":[179],"control":[180],"neohesperidin-related":[182],"supplements,":[184],"foods,":[185],"traditional":[186],"herbs":[187],"pharmaceutical":[189],"formulations.":[190]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}