{"id":"https://openalex.org/W1913680946","doi":null,"title":"Generation and characterization of a monoclonal antibody with specificity for Mycoplasma arginini.","display_name":"Generation and characterization of a monoclonal antibody with specificity for Mycoplasma arginini.","publication_year":2007,"publication_date":"2007-12-01","ids":{"openalex":"https://openalex.org/W1913680946","mag":"1913680946","pmid":"https://pubmed.ncbi.nlm.nih.gov/18176539"},"language":"en","primary_location":{"id":"pmid:18176539","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18176539","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of microbiology (Seoul, Korea)","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045191700","display_name":"Yeon Sung Son","orcid":"https://orcid.org/0009-0009-8296-0841","observed_orcids":["https://orcid.org/0009-0009-8296-0841"]},"institutions":[{"id":"https://openalex.org/I73616290","display_name":"Korea Research Institute of Bioscience and Biotechnology","ror":"https://ror.org/03ep23f07","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210144908","https://openalex.org/I4387152098","https://openalex.org/I73616290"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yeon Sung Son","raw_affiliation_strings":["Therapeutic Antibody Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejon, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Therapeutic Antibody Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejon, Republic of Korea","institution_ids":["https://openalex.org/I73616290"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108436049","display_name":"Hyo Jeong Hong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hyo Jeong Hong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.08912201,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"45","issue":"6","first_page":"547","last_page":"52"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9193999767303467,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9193999767303467,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.009399999864399433,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/monoclonal-antibodies","display_name":"monoclonal antibodies","score":0.875},{"id":"https://openalex.org/keywords/mycoplasma-arginini","display_name":"Mycoplasma arginini","score":0.9959999918937683},{"id":"https://openalex.org/keywords/human-embryonic-stem-cells","display_name":"human embryonic stem cells","score":0.9480000138282776},{"id":"https://openalex.org/keywords/cell-surface-markers","display_name":"cell surface markers","score":0.5989999771118164},{"id":"https://openalex.org/keywords/mycoplasma-infection","display_name":"mycoplasma infection","score":0.7480000257492065},{"id":"https://openalex.org/keywords/self-renewal","display_name":"self-renewal","score":0.7229999899864197},{"id":"https://openalex.org/keywords/pluripotency","display_name":"pluripotency","score":0.9850000143051147},{"id":"https://openalex.org/keywords/antibody-characterization","display_name":"antibody characterization","score":0.37299999594688416}],"concepts":[{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.7555656433105469},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.7074315547943115},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6236092448234558},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6137208938598633},{"id":"https://openalex.org/C204628709","wikidata":"https://www.wikidata.org/wiki/Q864854","display_name":"Biotinylation","level":2,"score":0.5135972499847412},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.44469475746154785},{"id":"https://openalex.org/C2778838687","wikidata":"https://www.wikidata.org/wiki/Q210975","display_name":"Mycoplasma","level":2,"score":0.4250863492488861},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.4148465394973755},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11791619658470154},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.11660036444664001},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0979529321193695},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000918","descriptor_name":"Antibody Specificity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009174","descriptor_name":"Mycoplasma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019921","descriptor_name":"Biotinylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039904","descriptor_name":"Pluripotent Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D039904","descriptor_name":"Pluripotent Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D047468","descriptor_name":"Immunoprecipitation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053595","descriptor_name":"Embryonic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D053595","descriptor_name":"Embryonic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:18176539","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18176539","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of microbiology (Seoul, Korea)","raw_type":"Journal Article"},{"id":"pmh:oai:http://repository.kribb.re.kr:8080/:201005/8210","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/201005/8210","pdf_url":null,"source":{"id":"https://openalex.org/S4406922719","display_name":"KRIBB Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"/dspace/upload/original/7355.pdf","raw_type":"Article"},{"id":"pmh:oai:https://repository.kribb.re.kr:201005/8210","doi":null,"is_oa":false,"landing_page_url":"https://repository.kribb.re.kr/handle/201005/8210","pdf_url":null,"source":{"id":"https://openalex.org/S4406922719","display_name":"KRIBB Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"/dspace/upload/original/7355.pdf","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1518310590","https://openalex.org/W1979112028","https://openalex.org/W2033284482","https://openalex.org/W2046241907","https://openalex.org/W2086943348","https://openalex.org/W2091790925","https://openalex.org/W2094557730","https://openalex.org/W2101650913","https://openalex.org/W2136780582","https://openalex.org/W2138442302","https://openalex.org/W2155062057","https://openalex.org/W2158343596","https://openalex.org/W2219890800"],"related_works":["https://openalex.org/W2067574976","https://openalex.org/W1992264594","https://openalex.org/W133718522","https://openalex.org/W2093646730","https://openalex.org/W195627623","https://openalex.org/W2081123962","https://openalex.org/W1981810661","https://openalex.org/W1966427975","https://openalex.org/W7098913459","https://openalex.org/W1979112028"],"abstract_inverted_index":{"Previously,":[0],"we":[1],"generated":[2],"monoclonal":[3],"antibodies":[4],"(MAbs)":[5],"that":[6,90,105,123],"bound":[7,40],"to":[8,20,41,51,93,118,126],"the":[9,42,71,79,103,116,121],"surface":[10,24,43],"of":[11,44,73,78,84,97,102,112],"human":[12],"embryonic":[13,56,139],"stem":[14],"cells":[15,58],"(hESCs)":[16],"in":[17,59,110],"an":[18],"attempt":[19],"discover":[21],"new":[22],"hESC-specific":[23],"markers.":[25],"In":[26],"this":[27],"study,":[28],"MAb":[29,39],"47-235":[30,91,108,127],"(IgG1,":[31],"kappa)":[32],"was":[33],"selected":[34],"for":[35],"further":[36],"characterization.":[37],"The":[38,63],"undifferentiated":[45],"hESCs":[46,104,122],"but":[47],"did":[48],"not":[49],"bind":[50],"mouse":[52,55],"ESCs":[53],"or":[54],"fibroblast":[57],"flow":[60],"cytometric":[61],"analysis.":[62],"antibody":[64],"immunoprecipitated":[65],"a":[66],"47":[67],"kDa":[68],"protein":[69,80,96],"from":[70],"lysates":[72],"cell":[74],"surface-biotinylated":[75],"hESCs.":[76],"Identification":[77],"by":[81],"quadrupole":[82],"time":[83],"flight":[85],"tandem":[86],"mass":[87],"spectrometry":[88],"revealed":[89],"binds":[92],"Ag":[94],"243-5":[95],"Mycoplasma":[98],"arginini.":[99],"BM-Cyclin":[100],"treatment":[101],"reacted":[106],"with":[107],"resulted":[109],"loss":[111],"mycoplasma":[113],"DNA":[114],"and":[115,130,132],"reactivity":[117],"47-235.":[119],"Nevertheless,":[120],"were":[124],"reactive":[125],"maintained":[128],"self-renewal":[129],"pluripotency":[131],"thus":[133],"could":[134],"be":[135],"differentiated":[136],"into":[137],"three":[138],"germ":[140],"layers.":[141]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}