{"id":"https://openalex.org/W1912900577","doi":"https://doi.org/10.1002/jor.22831","title":"Tripeptide\u2013copper complex GHK\u2010Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction","display_name":"Tripeptide\u2013copper complex GHK\u2010Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction","publication_year":2015,"publication_date":"2015-03-02","ids":{"openalex":"https://openalex.org/W1912900577","doi":"https://doi.org/10.1002/jor.22831","mag":"1912900577","pmid":"https://pubmed.ncbi.nlm.nih.gov/25731775"},"language":"en","primary_location":{"id":"doi:10.1002/jor.22831","doi":"https://doi.org/10.1002/jor.22831","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jor.22831","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jor.22831","source":{"id":"https://openalex.org/S12558119","display_name":"Journal of Orthopaedic Research\u00ae","issn_l":"0736-0266","issn":["0736-0266","1554-527X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jor.22831","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108059448","display_name":"Sai\u2010Chuen Fu","orcid":"https://orcid.org/0000-0001-5865-6801","observed_orcids":["https://orcid.org/0000-0001-5865-6801"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4405270569","display_name":"Lui Che Woo Institute of Innovative Medicine","ror":"https://ror.org/00y8ke806","country_code":"HK","type":"other","lineage":["https://openalex.org/I4405270569"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Sai\u2010Chuen Fu","raw_affiliation_strings":["Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","Lui Che Woo Institute of Innovative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Lui Che Woo Institute of Innovative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4405270569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078633743","display_name":"Yau\u2010Chuk Cheuk","orcid":"https://orcid.org/0000-0003-1023-1243","observed_orcids":["https://orcid.org/0000-0003-1023-1243"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4405270569","display_name":"Lui Che Woo Institute of Innovative Medicine","ror":"https://ror.org/00y8ke806","country_code":"HK","type":"other","lineage":["https://openalex.org/I4405270569"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Yau\u2010Chuk Cheuk","raw_affiliation_strings":["Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","Lui Che Woo Institute of Innovative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Lui Che Woo Institute of Innovative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4405270569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075750709","display_name":"Wai Yin Vivien Chiu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4405270569","display_name":"Lui Che Woo Institute of Innovative Medicine","ror":"https://ror.org/00y8ke806","country_code":"HK","type":"other","lineage":["https://openalex.org/I4405270569"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Wai\u2010Yin Vivien Chiu","raw_affiliation_strings":["Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","Lui Che Woo Institute of Innovative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Lui Che Woo Institute of Innovative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4405270569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027232625","display_name":"Patrick Shu\u2010Hang Yung","orcid":"https://orcid.org/0000-0002-7214-5503","observed_orcids":["https://orcid.org/0000-0002-7214-5503"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4405270569","display_name":"Lui Che Woo Institute of Innovative Medicine","ror":"https://ror.org/00y8ke806","country_code":"HK","type":"other","lineage":["https://openalex.org/I4405270569"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Shu\u2010Hang Yung","raw_affiliation_strings":["Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","Lui Che Woo Institute of Innovative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Lui Che Woo Institute of Innovative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4405270569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111962062","display_name":"Christer Gustav Rolf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["HK","SE"],"is_corresponding":false,"raw_author_name":"Christer G. Rolf","raw_affiliation_strings":["Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","Division of Orthopedics and Biotechnology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Division of Orthopedics and Biotechnology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111888644","display_name":"Kai-Ming Chan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4405270569","display_name":"Lui Che Woo Institute of Innovative Medicine","ror":"https://ror.org/00y8ke806","country_code":"HK","type":"other","lineage":["https://openalex.org/I4405270569"]}],"countries":["HK"],"is_corresponding":true,"raw_author_name":"Kai\u2010Ming Chan","raw_affiliation_strings":["Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","Lui Che Woo Institute of Innovative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Lui Che Woo Institute of Innovative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4405270569"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5111888644"],"corresponding_institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4405270569"],"apc_list":{"value":3970,"currency":"USD","value_usd":3970},"apc_paid":null,"fwci":1.6062,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.81461248,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"33","issue":"7","first_page":"1024","last_page":"1033"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10442","display_name":"Knee injuries and reconstruction techniques","score":0.8471999764442444,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10442","display_name":"Knee injuries and reconstruction techniques","score":0.8471999764442444,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11068","display_name":"Tendon Structure and Treatment","score":0.10499999672174454,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.019099999219179153,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ghk-cu","display_name":"GHK-Cu","score":0.9670000076293945},{"id":"https://openalex.org/keywords/anterior-cruciate-ligament-reconstruction","display_name":"anterior cruciate ligament reconstruction","score":0.9980000257492065},{"id":"https://openalex.org/keywords/graft-healing","display_name":"graft healing","score":0.9739999771118164},{"id":"https://openalex.org/keywords/graft-failure","display_name":"graft failure","score":0.8809999823570251},{"id":"https://openalex.org/keywords/tissue-remodeling","display_name":"tissue remodeling","score":0.6769999861717224},{"id":"https://openalex.org/keywords/intra-articular-injection","display_name":"intra-articular injection","score":0.9120000004768372},{"id":"https://openalex.org/keywords/knee-laxity","display_name":"knee laxity","score":0.9070000052452087},{"id":"https://openalex.org/keywords/graft-stiffness","display_name":"graft stiffness","score":0.8899999856948853},{"id":"https://openalex.org/keywords/rat-model","display_name":"rat model","score":0.46799999475479126}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7732648253440857},{"id":"https://openalex.org/C2777397205","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Saline","level":2,"score":0.7017040848731995},{"id":"https://openalex.org/C2780887989","wikidata":"https://www.wikidata.org/wiki/Q4771338","display_name":"Anterior cruciate ligament reconstruction","level":3,"score":0.5475755929946899},{"id":"https://openalex.org/C2778434673","wikidata":"https://www.wikidata.org/wiki/Q611127","display_name":"Anterior cruciate ligament","level":2,"score":0.5241173505783081},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.46729758381843567},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.35659635066986084},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22326922416687012}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005684","descriptor_name":"Gait","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007270","descriptor_name":"Injections, Intra-Articular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007593","descriptor_name":"Joint Instability","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019737","descriptor_name":"Transplants","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D019737","descriptor_name":"Transplants","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D059549","descriptor_name":"Anterior Cruciate Ligament Reconstruction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/jor.22831","doi":"https://doi.org/10.1002/jor.22831","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jor.22831","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jor.22831","source":{"id":"https://openalex.org/S12558119","display_name":"Journal of Orthopaedic Research\u00ae","issn_l":"0736-0266","issn":["0736-0266","1554-527X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Research","raw_type":"journal-article"},{"id":"pmid:25731775","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25731775","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of orthopaedic research : official publication of the Orthopaedic Research Society","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/jor.22831","doi":"https://doi.org/10.1002/jor.22831","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jor.22831","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jor.22831","source":{"id":"https://openalex.org/S12558119","display_name":"Journal of Orthopaedic Research\u00ae","issn_l":"0736-0266","issn":["0736-0266","1554-527X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322942","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1912900577.pdf","grobid_xml":"https://content.openalex.org/works/W1912900577.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1608695502","https://openalex.org/W1939057043","https://openalex.org/W1963784303","https://openalex.org/W1967187506","https://openalex.org/W1969695080","https://openalex.org/W1988686189","https://openalex.org/W1988934161","https://openalex.org/W1997614336","https://openalex.org/W2006095611","https://openalex.org/W2011085726","https://openalex.org/W2027981213","https://openalex.org/W2041732279","https://openalex.org/W2042519841","https://openalex.org/W2048604783","https://openalex.org/W2050838512","https://openalex.org/W2051142727","https://openalex.org/W2051512896","https://openalex.org/W2052616514","https://openalex.org/W2056297889","https://openalex.org/W2084686703","https://openalex.org/W2091151986","https://openalex.org/W2111022082","https://openalex.org/W2115112344","https://openalex.org/W2134799343","https://openalex.org/W2137188329","https://openalex.org/W2165659940","https://openalex.org/W2409360393","https://openalex.org/W4235282624"],"related_works":["https://openalex.org/W3033033016","https://openalex.org/W2050838512","https://openalex.org/W3160339452","https://openalex.org/W1969695080","https://openalex.org/W2244928437","https://openalex.org/W1978845322","https://openalex.org/W2016228233","https://openalex.org/W4200390405","https://openalex.org/W2555219817","https://openalex.org/W1985079205"],"abstract_inverted_index":{"After":[0],"anterior":[1],"cruciate":[2],"ligament":[3],"reconstruction":[4],"(ACLR),":[5],"the":[6,10,122,142,200],"biological":[7],"healing":[8,41,194],"of":[9,31],"graft":[11,20,40,99,139,193],"is":[12,27],"a":[13,28,71,112,187],"rate-limiting":[14],"step":[15],"which":[16],"can":[17,38],"contribute":[18],"to":[19,51,121],"failure.":[21],"The":[22,138],"tripeptide-copper":[23],"complex":[24,140],"glycyl-L-histidyl-L-lysine-Cu(II)":[25],"(GHK-Cu)":[26],"well-known":[29],"activator":[30],"tissue":[32],"remodeling.":[33],"We":[34],"investigated":[35],"whether":[36],"GHK-Cu":[37,57,108,145,191],"improve":[39],"following":[42,195],"ACLR.":[43],"Seventy-two":[44],"rats":[45],"underwent":[46],"unilateral":[47],"ACLR":[48,196],"were":[49,65,93],"randomized":[50],"saline,":[52],"0.3":[53,143],"or":[54,87],"3":[55],"mg/ml":[56,144],"groups":[58,109],"(n":[59],"=":[60,126,158],"24).":[61],"Post-operational":[62],"intra-articular":[63],"injections":[64],"given":[66],"from":[67],"week":[68],"2,":[69],"once":[70],"week,":[72],"for":[73,95],"4":[74],"weeks.":[75],"Gait":[76],"analysis":[77],"was":[78,130,162],"performed":[79],"pre-injury":[80],"and":[81,102,171],"at":[82,134,153],"harvesting":[83],"time.":[84],"At":[85,104],"6":[86,105,154],"12":[88,135],"weeks":[89,106,136,155],"post-operation,":[90],"knee":[91,96,117],"specimens":[92],"harvested":[94],"laxity":[97,118],"test,":[98,101],"pull-out":[100,182],"histology.":[103],"post-ACLR,":[107],"resulted":[110],"in":[111,116,141,166,197],"smaller":[113],"side-to-side":[114],"difference":[115,133,165],"as":[119,206],"compared":[120],"saline":[123,151],"group":[124,146,152],"(p":[125,157],"0.009),":[127],"but":[128,160,199],"there":[129,161],"no":[131,163],"significant":[132,164],"post-operation.":[137],"had":[147],"higher":[148],"stiffness":[149],"than":[150],"post-operation":[156],"0.026),":[159],"ultimate":[167],"load,":[168],"gait":[169],"parameters,":[170],"histological":[172],"scores":[173],"among":[174],"treatment":[175,207],"groups.":[176],"All":[177],"grafts":[178],"failed":[179],"mid-substance":[180],"during":[181],"test.":[183],"Intra-articular":[184],"supplementation":[185],"with":[186],"bioactive":[188],"small":[189],"molecule":[190],"improved":[192],"rat,":[198],"beneficial":[201],"effects":[202],"could":[203],"not":[204],"last":[205],"discontinued.":[208]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}