{"id":"https://openalex.org/W1908788141","doi":"https://doi.org/10.1089/jwh.2013.4479","title":"Selection of Contraceptive Therapy for Patients with Thrombophilia: A Review of the Evidence","display_name":"Selection of Contraceptive Therapy for Patients with Thrombophilia: A Review of the Evidence","publication_year":2014,"publication_date":"2014-02-19","ids":{"openalex":"https://openalex.org/W1908788141","doi":"https://doi.org/10.1089/jwh.2013.4479","mag":"1908788141","pmid":"https://pubmed.ncbi.nlm.nih.gov/24552487"},"language":"en","primary_location":{"id":"doi:10.1089/jwh.2013.4479","doi":"https://doi.org/10.1089/jwh.2013.4479","is_oa":false,"landing_page_url":"https://doi.org/10.1089/jwh.2013.4479","pdf_url":null,"source":{"id":"https://openalex.org/S191117624","display_name":"Journal of Women s Health","issn_l":"1059-7115","issn":["1059-7115","1540-9996","1931-843X","2168-7668"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Women's Health","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045312171","display_name":"Whitney D. Maxwell","orcid":"https://orcid.org/0000-0002-3287-6758","observed_orcids":["https://orcid.org/0000-0002-3287-6758","https://orcid.org/0000-0002-2408-0733"]},"institutions":[{"id":"https://openalex.org/I155781252","display_name":"University of South Carolina","ror":"https://ror.org/02b6qw903","country_code":"US","type":"education","lineage":["https://openalex.org/I155781252"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Whitney D. Maxwell","raw_affiliation_strings":["Department of Clinical Pharmacy and Outcomes Sciences, South Carolina College of Pharmacy, University of South Carolina, Columbia, South Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy and Outcomes Sciences, South Carolina College of Pharmacy, University of South Carolina, Columbia, South Carolina","institution_ids":["https://openalex.org/I155781252"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Merna Jacob","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155781252","display_name":"University of South Carolina","ror":"https://ror.org/02b6qw903","country_code":"US","type":"education","lineage":["https://openalex.org/I155781252"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Merna Jacob","raw_affiliation_strings":["South Carolina College of Pharmacy, University of South Carolina, Columbia, South Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"South Carolina College of Pharmacy, University of South Carolina, Columbia, South Carolina","institution_ids":["https://openalex.org/I155781252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010856300","display_name":"Lisa Beth Spiryda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa B. Spiryda","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Florida, College of Medicine, Gainesville, Florida"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Florida, College of Medicine, Gainesville, Florida","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101653484","display_name":"Charles L. Bennett","orcid":"https://orcid.org/0000-0003-2475-3915","observed_orcids":["https://orcid.org/0000-0003-2475-3915"]},"institutions":[{"id":"https://openalex.org/I155781252","display_name":"University of South Carolina","ror":"https://ror.org/02b6qw903","country_code":"US","type":"education","lineage":["https://openalex.org/I155781252"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles L. Bennett","raw_affiliation_strings":["Department of Clinical Pharmacy and Outcomes Sciences, South Carolina College of Pharmacy, University of South Carolina, Columbia, South Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy and Outcomes Sciences, South Carolina College of Pharmacy, University of South Carolina, Columbia, South Carolina","institution_ids":["https://openalex.org/I155781252"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5045312171"],"corresponding_institution_ids":["https://openalex.org/I155781252"],"apc_list":null,"apc_paid":null,"fwci":0.1169,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.12698413,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"23","issue":"4","first_page":"318","last_page":"326"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.4717000126838684,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.4717000126838684,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.3208000063896179,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10600","display_name":"Reproductive Health and Contraception","score":0.19419999420642853,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thrombophilia","display_name":"thrombophilia","score":0.9959999918937683},{"id":"https://openalex.org/keywords/contraception","display_name":"contraception","score":0.5870000123977661},{"id":"https://openalex.org/keywords/venous-thromboembolism","display_name":"venous thromboembolism","score":0.9890000224113464},{"id":"https://openalex.org/keywords/combined-hormonal-contraception","display_name":"combined hormonal contraceptives","score":0.8209999799728394},{"id":"https://openalex.org/keywords/thrombotic-risk","display_name":"thrombosis risk","score":0.8080000281333923},{"id":"https://openalex.org/keywords/contraceptive-counseling","display_name":"contraceptive counseling","score":0.8690000176429749},{"id":"https://openalex.org/keywords/women-s-health","display_name":"women's health","score":0.39399999380111694}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9031260013580322},{"id":"https://openalex.org/C2780842393","wikidata":"https://www.wikidata.org/wiki/Q1570013","display_name":"Thrombophilia","level":3,"score":0.8803399801254272},{"id":"https://openalex.org/C2776172332","wikidata":"https://www.wikidata.org/wiki/Q7292449","display_name":"Hormonal contraception","level":5,"score":0.6697177886962891},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5839340686798096},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.5435724854469299},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.5235464572906494},{"id":"https://openalex.org/C518429986","wikidata":"https://www.wikidata.org/wiki/Q964401","display_name":"Fertility","level":3,"score":0.4242158532142639},{"id":"https://openalex.org/C2779076696","wikidata":"https://www.wikidata.org/wiki/Q1280670","display_name":"Family planning","level":4,"score":0.40655961632728577},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.31183090806007385},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1277581751346588},{"id":"https://openalex.org/C2986817661","wikidata":"https://www.wikidata.org/wiki/Q185698","display_name":"Research methodology","level":3,"score":0.06663566827774048},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003267","descriptor_name":"Contraception","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003278","descriptor_name":"Contraceptives, Oral, Hormonal","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D005165","descriptor_name":"Factor V","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019851","descriptor_name":"Thrombophilia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D054556","descriptor_name":"Venous Thromboembolism","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D054556","descriptor_name":"Venous Thromboembolism","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1089/jwh.2013.4479","doi":"https://doi.org/10.1089/jwh.2013.4479","is_oa":false,"landing_page_url":"https://doi.org/10.1089/jwh.2013.4479","pdf_url":null,"source":{"id":"https://openalex.org/S191117624","display_name":"Journal of Women s Health","issn_l":"1059-7115","issn":["1059-7115","1540-9996","1931-843X","2168-7668"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Women's Health","raw_type":"journal-article"},{"id":"pmid:24552487","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24552487","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of women's health (2002)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320314102","display_name":"South Carolina Center of Economic Excellence","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":78,"referenced_works":["https://openalex.org/W1540638259","https://openalex.org/W1548764206","https://openalex.org/W1584327144","https://openalex.org/W1607345336","https://openalex.org/W1834120352","https://openalex.org/W1891126000","https://openalex.org/W1919006336","https://openalex.org/W1966306892","https://openalex.org/W1967108695","https://openalex.org/W1985802022","https://openalex.org/W1986999852","https://openalex.org/W1989441410","https://openalex.org/W1990107586","https://openalex.org/W1997402802","https://openalex.org/W1999011481","https://openalex.org/W1999361503","https://openalex.org/W2002183497","https://openalex.org/W2002497857","https://openalex.org/W2010275186","https://openalex.org/W2016492461","https://openalex.org/W2019818341","https://openalex.org/W2023929943","https://openalex.org/W2025942899","https://openalex.org/W2027492515","https://openalex.org/W2038526384","https://openalex.org/W2039130059","https://openalex.org/W2039780016","https://openalex.org/W2041919675","https://openalex.org/W2043161810","https://openalex.org/W2043306284","https://openalex.org/W2044341259","https://openalex.org/W2046837674","https://openalex.org/W2054330426","https://openalex.org/W2058683934","https://openalex.org/W2061920971","https://openalex.org/W2064736463","https://openalex.org/W2071562548","https://openalex.org/W2073571473","https://openalex.org/W2076705357","https://openalex.org/W2081165872","https://openalex.org/W2084532855","https://openalex.org/W2086594833","https://openalex.org/W2098920585","https://openalex.org/W2100219711","https://openalex.org/W2100560126","https://openalex.org/W2101727819","https://openalex.org/W2104062454","https://openalex.org/W2104086174","https://openalex.org/W2104315137","https://openalex.org/W2115436778","https://openalex.org/W2124583955","https://openalex.org/W2124623256","https://openalex.org/W2127941969","https://openalex.org/W2128022832","https://openalex.org/W2131099415","https://openalex.org/W2132819365","https://openalex.org/W2136972207","https://openalex.org/W2138612542","https://openalex.org/W2142757660","https://openalex.org/W2143881211","https://openalex.org/W2147348413","https://openalex.org/W2147383560","https://openalex.org/W2147556011","https://openalex.org/W2151060265","https://openalex.org/W2151495168","https://openalex.org/W2153137569","https://openalex.org/W2153677157","https://openalex.org/W2158347304","https://openalex.org/W2163747366","https://openalex.org/W2167745220","https://openalex.org/W2169143572","https://openalex.org/W2173715092","https://openalex.org/W2339659421","https://openalex.org/W3021852519","https://openalex.org/W3188476032","https://openalex.org/W4211246758","https://openalex.org/W4233187059","https://openalex.org/W4236335263"],"related_works":["https://openalex.org/W4410218616","https://openalex.org/W4405108905","https://openalex.org/W7162639492","https://openalex.org/W2337148459","https://openalex.org/W111580850","https://openalex.org/W2089131154","https://openalex.org/W2158347304","https://openalex.org/W2159591939","https://openalex.org/W2914919587","https://openalex.org/W2058683934"],"abstract_inverted_index":{"BACKGROUND:":[0],"Awareness":[1],"of":[2,5,31,48,65,88,110,167],"the":[3,16,66,108,113,165],"contributions":[4],"thrombophilia":[6,111,129],"to":[7,61,97,162],"thrombosis-related":[8],"morbidity":[9],"and":[10,81,112],"mortality":[11],"has":[12],"been":[13,35],"growing":[14,44],"in":[15,24,71,100,102,123,142,152,170],"last":[17],"few":[18],"decades.":[19],"Thrombophilia":[20],"is":[21],"especially":[22],"concerning":[23],"females":[25],"seeking":[26],"contraception":[27,33,50,151],"because":[28],"some":[29],"types":[30],"hormonal":[32,90],"have":[34],"associated":[36],"with":[37,73,104,128,154],"venous":[38],"thromboembolism":[39],"(VTE).":[40],"Clinicians":[41],"face":[42],"a":[43,63,95],"need":[45],"for":[46,52,83,150],"awareness":[47],"evidence-based":[49],"selection":[51,80],"this":[53,84,143,171],"population.":[54,85,144,172],"METHODS:":[55],"PubMed":[56],"literature":[57,67],"searches":[58],"were":[59,130],"conducted":[60],"provide":[62,136],"review":[64,76],"describing":[68,120],"contraceptive":[69,79,91,125],"use":[70,93,169],"patients":[72,153],"thrombophilia.":[74],"This":[75],"also":[77],"describes":[78],"counseling":[82],"RESULTS:":[86],"Studies":[87],"combined":[89],"(CHC)":[92],"demonstrate":[94],"2-":[96],"50-fold":[98],"increase":[99],"VTE":[101,121,140],"individuals":[103],"thrombophilia,":[105],"depending":[106],"on":[107],"type":[109],"reference":[114],"group":[115],"identified.":[116],"Two":[117],"small":[118],"studies":[119,158],"incidence":[122],"progesterone-only":[124],"(POC)":[126],"users":[127],"identified":[131],"but":[132,157],"they":[133],"did":[134],"not":[135],"conclusive":[137],"information":[138],"regarding":[139],"risk":[141],"CONCLUSIONS:":[145],"POC":[146,168],"may":[147],"be":[148,160],"recommended":[149],"most":[155],"thrombophilias,":[156],"should":[159],"undertaken":[161],"further":[163],"define":[164],"safety":[166]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}