{"id":"https://openalex.org/W1902964951","doi":null,"title":"Distribution and phylogeny of the bacterial translational GTPases and the Mqsr/YgiT regulatory system","display_name":"Distribution and phylogeny of the bacterial translational GTPases and the Mqsr/YgiT regulatory system","publication_year":2013,"publication_date":"2013-08-30","ids":{"openalex":"https://openalex.org/W1902964951","mag":"1902964951"},"language":"en","primary_location":{"id":"pmh:oai:dspace.ut.ee:10062/32571","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10062/32571","pdf_url":null,"source":{"id":"https://openalex.org/S4306401412","display_name":"DSpace repository (University of Tartu)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I56085075","host_organization_name":"University of Tartu","host_organization_lineage":["https://openalex.org/I56085075"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083990946","display_name":"T\u00f5nu Margus","orcid":"https://orcid.org/0000-0003-4966-1291","observed_orcids":["https://orcid.org/0000-0003-4966-1291"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"T\u00f5nu Margus","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4966-1291","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5083990946"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.801800012588501,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.801800012588501,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.17239999771118164,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.01600000075995922,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/translational-gtpases","display_name":"translational GTPases","score":0.902999997138977},{"id":"https://openalex.org/keywords/toxin-antitoxin-systems","display_name":"toxin-antitoxin systems","score":0.9440000057220459},{"id":"https://openalex.org/keywords/bacterial-ribosome","display_name":"bacterial ribosome","score":0.5270000100135803},{"id":"https://openalex.org/keywords/gene-family-evolution","display_name":"gene family evolution","score":0.6359999775886536},{"id":"https://openalex.org/keywords/gene-duplication","display_name":"gene duplication","score":0.621999979019165},{"id":"https://openalex.org/keywords/functional-innovation","display_name":"functional innovation","score":0.8429999947547913},{"id":"https://openalex.org/keywords/phylogenetic-analysis","display_name":"phylogenetic analysis","score":0.550000011920929},{"id":"https://openalex.org/keywords/ribosome-associated-proteins","display_name":"ribosome-associated proteins","score":0.4259999990463257},{"id":"https://openalex.org/keywords/ribosome-associated-gtpase","display_name":"ribosome-associated GTPase","score":0.5289999842643738}],"concepts":[{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.6575390696525574},{"id":"https://openalex.org/C207332259","wikidata":"https://www.wikidata.org/wiki/Q769143","display_name":"GTPase","level":2,"score":0.5861182808876038},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5296131372451782},{"id":"https://openalex.org/C110121322","wikidata":"https://www.wikidata.org/wiki/Q865811","display_name":"Distribution (mathematics)","level":2,"score":0.5114880800247192},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47657299041748047},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.4279102683067322},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.27291589975357056},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1747080385684967},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.07856306433677673},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:dspace.ut.ee:10062/32571","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10062/32571","pdf_url":null,"source":{"id":"https://openalex.org/S4306401412","display_name":"DSpace repository (University of Tartu)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I56085075","host_organization_name":"University of Tartu","host_organization_lineage":["https://openalex.org/I56085075"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:1902964951","doi":null,"is_oa":false,"landing_page_url":"https://dspace.ut.ee/bitstream/10062/32571/1/margus_t6nu.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7095358494","https://openalex.org/W1939105798","https://openalex.org/W2021230200","https://openalex.org/W7097023512","https://openalex.org/W2527619150","https://openalex.org/W2524238351","https://openalex.org/W7100648914","https://openalex.org/W2525815396","https://openalex.org/W7065809861","https://openalex.org/W7120274115"],"abstract_inverted_index":{"Valgud":[0],"on":[1,10,60,83,108,113,128,169,182,250,256,278,294,319,349,432,451],"raku":[2,118],"ehituskivideks":[3],"ja":[4,67,99,116,139,143,176,246,259,268,305,340,360,393,401,417,437],"eluks":[5],"vajalike":[6],"reaktsioonide":[7],"katal\u00fc\u00fcsijateks.":[8],"Bioinformaatika":[9],"meid":[11],"varustanud":[12],"v\u00f5imsate":[13],"j\u00e4rjestuste":[14,402],"anal\u00fc\u00fcsi":[15],"vahenditega.":[16],"J\u00e4rjestuse":[17],"sarnasuse":[18],"alusel":[19],"grupeeruvad":[20],"valgud":[21,39],"perekondadeks.":[22],"Valguperekonna":[23],"moodustavad":[24],"homoloogsed":[25],"j\u00e4rjestused":[26],"ehk":[27],"siis":[28],"j\u00e4rjestused,":[29],"mis":[30,318,370],"p\u00e4rinevad":[31,50],"samast":[32],"eellasj\u00e4rjestusest.":[33],"Tihti":[34,53],"omavad":[35],"samasse":[36],"perekonda":[37],"kuuluvad":[38],"ka":[40,212,257],"sama":[41],"v\u00f5i":[42,58,62],"\u00fcksteisele":[43],"l\u00e4hedast":[44],"funktsiooni.":[45],"Meie":[46],"teadmised":[47],"valkude":[48],"funktsioonidest":[49],"\u00fcksikutelt":[51],"mudelorganismidelt.":[52],"huvitab":[54],"teadlasi":[55],"kui":[56,427],"universaalne":[57],"spetsiifiline":[59],"\u00fcks":[61],"teine":[63,269,422],"kirjeldatud":[64],"funktsioon.":[65],"Kuidas":[66],"millal":[68],"evolutsiooni":[69,142],"k\u00e4igus":[70],"tekib":[71],"olemasolevast":[72],"materjalist":[73],"uute":[74],"omadustega":[75],"(uue":[76],"funktsiooniga)":[77],"valk":[78],"l\u00e4bi":[79],"geeniduplikatsiooni?":[80],"Kui":[81],"tihti":[82],"sellised":[84],"s\u00fcndmused":[85],"evolutsioonilises":[86],"ajaskaalas":[87],"aset":[88],"leidud?":[89],"\\nOma":[90],"t\u00f6\u00f6s":[91],"olen":[92],"ma":[93],"anal\u00fc\u00fcsinud":[94],"bakterite":[95,206],"translatsioonilisi":[96],"GTPaase":[97],"(trGTPaas)":[98],"mqsR/ygiT":[100],"toksiin-antitoksiin":[101],"(TA)":[102],"s\u00fcsteemi":[103],"valke.":[104,123],"\u00dchiseks":[105],"nime\u00ac\u00actajaks":[106],"m\u00f5lemale":[107],"valgus\u00fcnteesi":[109,185],"aparaat":[110],"\u2013":[111,156,218],"m\u00f5lemad":[112],"seotud":[114,138],"ribosoomiga":[115],"sealtkaudu":[117],"v\u00f5imega":[119],"s\u00f5ltuvalt":[120],"vajadusele":[121],"toota":[122],"\\nK\u00fcsimused,":[124],"mida":[125],"selles":[126],"kontekstis":[127],"k\u00fcsitud,":[129],"saab":[130],"laias":[131],"laastus":[132],"jagada":[133,239],"kaheks:":[134],"a)":[135],"valguperekonna":[136,141],"esindatusega":[137],"b)":[140],"funktsionaalse":[144],"innovatsiooniga":[145],"seotud.":[146],"Translatsiooniliste":[147],"GTPaaside":[148],"puhul":[149],"bakterites":[150,170],"saame":[151],"r\u00e4\u00e4kida":[152],"\u00fcheksast":[153,157,166],"erinevast":[154,158],"perekonnast":[155,168],"funktsioonide":[159],"komplektist.":[160],"T\u00e4isgenoomidele":[161],"p\u00f5hinev":[162],"anal\u00fc\u00fcs":[163,210,230,283,403],"n\u00e4itas,":[164],"et":[165,180,233,261],"trGTPaaside":[167],"konserveerunud":[171,321],"neli:":[172],"IF2,":[173],"EF-Tu,":[174],"EFG":[175,214,227,236,242,247,253,275,288,310,323,326,425,433,444],"LepA(EF4).":[177],"Vaatamata":[178],"sellele,":[179],"RF3\u2019e":[181],"omistatud":[183],"klassikalise":[184],"mudeli":[186],"valguses":[187],"kanooniline":[188],"roll":[189,435],"translatsiooni":[190],"l\u00f5petamisel,":[191],"puudus":[192],"RF3":[193],"geen":[194],"ligikaudu":[195],"40%":[196],"anal\u00fc\u00fcsitud":[197],"bakteri":[198],"genoomides.":[199],"Samas":[200],"aga":[201,279],"ebaselge":[202],"funktsiooniga":[203],"LepA":[204],"osutus":[205],"spetsiifiliseks":[207],"trGTPaasiks.":[208],"\\nEelnev":[209],"t\u00f5i":[211,231],"v\u00e4lja":[213],"paraloogide":[215],"laia":[216],"esinemise":[217],"paljud":[219],"bakteri\u00acgenoomid":[220],"sisaldasid":[221],"2\u20133":[222],"\u00fcksteisest":[223],"k\u00fcllaltki":[224],"erinevat":[225],"(divergeerunud)":[226],"geeni.":[228],"L\u00e4hem":[229],"v\u00e4lja,":[232],"kogu":[234],"varieeruvuse":[235],"perekonnas":[237],"v\u00f5ib":[238,313],"neljaks":[240],"alamperekonnaks:":[241],"I,":[243,445],"spdEFG1,":[244],"spdEFG2":[245],"II.":[248],"Eksperimentaalselt":[249],"h\u00e4sti":[251],"iseloomustatud":[252],"I.":[254],"Uuritud":[255],"spdEFG\u2019sid":[258],"leitud,":[260],"esimene":[262],"neist":[263],"omab":[264],"translokaasi":[265],"aktiivsust":[266],"translatsioonil":[267],"osaleb":[270],"ribosoomide":[271],"rets\u00fckleerimisel.":[272],"Laialt":[273],"levinud":[274],"II":[276,311,324,339,385,398,426,434],"alamperekond":[277],"halvasti":[280],"uuritud.":[281],"F\u00fclogeneetiline":[282],"v\u00f5imaldab":[284,376],"p\u00fcstitada":[285],"h\u00fcpoteesi":[286],"nelja":[287],"alamperekonna":[289,399],"iidsest":[290],"p\u00e4ritolust,":[291],"st.":[292],"nad":[293],"tekkinud":[295],"ajalises":[296],"skaalas":[297],"enne":[298],"(v\u00f5i":[299],"samaaegselt)":[300],"eukar\u00fcootse":[301],"rakuvormi":[302],"lahknemist":[303],"arhedest":[304],"bakteritest.":[306],"Funktsionaalse":[307],"innovatsiooni":[308],"kandjaks":[309],"valgus":[312],"pidada":[314],"eelk\u00f5ige":[315],"12":[316],"positsiooni,":[317],"spetsiifiliselt":[320],"just":[322],"alamperekonnal.":[325],"II\u2019e":[327],"iseloomulikus":[328],"k\u00f5rge":[329],"divergentsuse":[330],"taustal":[331],"t\u00f5usevad":[332],"need":[333],"positsioonid":[334],"esile":[335],"GTPaasi":[336,345],"dom\u00e4\u00e4nis,":[337,346],"dom\u00e4\u00e4nis":[338],"neljandas":[341],"dom\u00e4\u00e4nis.":[342],"Konserveerunud":[343,382],"muutused":[344,383],"millest":[347],"osad":[348],"GTP\u2019d":[350],"siduvas":[351],"G1":[352],"motiivis,":[353],"v\u00f5imaldavad":[354],"teha":[355],"j\u00e4reldusi":[356],"muutunud":[357,388],"GTP":[358],"sidumise":[359],"h\u00fcdrol\u00fc\u00fcsi":[361],"tingimuste":[362],"kohta.":[363],"Suurenenud":[364],"laeng":[365],"neljanda":[366],"dom\u00e4\u00e4ni":[367],"lingu":[368],"otsas,":[369],"E.":[371],"coli":[372],"EFG\u2019l":[373],"siseneb":[374],"A-saiti,":[375],"spekuleerida":[377],"muutuse":[378],"\u00fcle":[379],"translokatsiooni":[380],"keskkonnas.":[381],"dom\u00e4\u00e4n":[384,391,394],"piirkonnas":[386],"viitavad":[387],"interaktsioonile":[389],"ribosoomi,":[390],"I":[392],"III":[395],"vahel.":[396],"\\nEFG":[397],"f\u00fclogeneetiline":[400],"n\u00e4itab":[404],"selgelt":[405],"h\u00f5imkonna/klassi":[406,428],"spetsiifiliste":[407],"alam-alamgruppide":[408],"olemasolu.":[409],"Need":[410],"alam-alamgrupid":[411],"erinevad":[412],"teineteisest":[413],"G2":[414],"motiivi":[415],"konserveeruvuse":[416],"insertsioonide/deletsioonide":[418],"mustri":[419],"alusel.":[420],"See":[421],"tase":[423],"kirjeldab":[424],"spetsiifilist":[429],"faktorit.":[430],"\\nMis":[431],"tegelikult":[436],"kuidas":[438],"ning":[439],"millistes":[440],"tingimustes":[441],"ta":[442],"komplementeerib":[443],"ootab":[446],"alles":[447],"vastuseid.":[448],"Antud":[449],"t\u00f6\u00f6":[450],"loonud":[452],"raamistiku":[453],"tulevaste":[454],"eksperimentide":[455],"tarvis.":[456]},"counts_by_year":[{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}