{"id":"https://openalex.org/W1900590072","doi":null,"title":"Lactational Vitamin E Protects Against the Histotoxic Effects of Systemically Administered Vanadium in Neonatal Rats.","display_name":"Lactational Vitamin E Protects Against the Histotoxic Effects of Systemically Administered Vanadium in Neonatal Rats.","publication_year":2014,"publication_date":"2014-12-29","ids":{"openalex":"https://openalex.org/W1900590072","mag":"1900590072","pmid":"https://pubmed.ncbi.nlm.nih.gov/26196578"},"language":"en","primary_location":{"id":"pmh:oai:ojshostng.com:article/1819","doi":null,"is_oa":true,"landing_page_url":"https://ojshostng.com/index.php/index/article/view/1819","pdf_url":null,"source":{"id":"https://openalex.org/S2764994983","display_name":"Nigerian Journal of Physiological Sciences","issn_l":"0794-859X","issn":["0794-859X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jpps-1","medline","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310321518","host_organization_name":"African Journals OnLine","host_organization_lineage":["https://openalex.org/P4310321518"],"host_organization_lineage_names":["African Journals OnLine"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0794-859X","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://ojshostng.com/index.php/index/article/view/1819","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072809757","display_name":"Francis Olaolorun","orcid":"https://orcid.org/0000-0002-2708-1627","observed_orcids":["https://orcid.org/0000-0002-2708-1627"]},"institutions":[{"id":"https://openalex.org/I181631907","display_name":"University of Ibadan","ror":"https://ror.org/03wx2rr30","country_code":"NG","type":"education","lineage":["https://openalex.org/I181631907"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"F A Olaolorun","raw_affiliation_strings":["Department of Veterinary Anatomy, University of Ibadan. jkayodeolopade@yahoo.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Anatomy, University of Ibadan. jkayodeolopade@yahoo.com","institution_ids":["https://openalex.org/I181631907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007991671","display_name":"Adedunsola Adewunmi Obasa","orcid":"https://orcid.org/0009-0001-4840-8190","observed_orcids":["https://orcid.org/0009-0001-4840-8190"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A A Obasa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134832896","display_name":"Hassan A. Balogun","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H A Balogun","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073463586","display_name":"Oluwagbemiga O. Aina","orcid":"https://orcid.org/0000-0002-0795-4785","observed_orcids":["https://orcid.org/0000-0002-0795-4785"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"O O Aina","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5112259945","display_name":"James Olukayode Olopade","orcid":"https://orcid.org/0000-0002-6388-5083","observed_orcids":["https://orcid.org/0000-0002-6388-5083"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J O Olopade","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"29","issue":"2","first_page":"125","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.5785999894142151,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.5785999894142151,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.19760000705718994,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12136","display_name":"Vanadium and Halogenation Chemistry","score":0.125900000333786,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-e","display_name":"vitamin E","score":0.8149999976158142},{"id":"https://openalex.org/keywords/lactation","display_name":"lactation","score":0.7480000257492065},{"id":"https://openalex.org/keywords/vanadium","display_name":"vanadium","score":0.7699999809265137},{"id":"https://openalex.org/keywords/sodium-metavanadate","display_name":"sodium metavanadate","score":0.9869999885559082},{"id":"https://openalex.org/keywords/histotoxicity","display_name":"histotoxicity","score":0.890999972820282},{"id":"https://openalex.org/keywords/neonatal-rats","display_name":"neonatal rats","score":0.7639999985694885},{"id":"https://openalex.org/keywords/testicular-toxicity","display_name":"testicular toxicity","score":0.7540000081062317},{"id":"https://openalex.org/keywords/pulmonary-toxicity","display_name":"pulmonary toxicity","score":0.6169999837875366},{"id":"https://openalex.org/keywords/hepatotoxicity","display_name":"hepatotoxicity","score":0.746999979019165},{"id":"https://openalex.org/keywords/maternal-supplementation","display_name":"maternal supplementation","score":0.5379999876022339},{"id":"https://openalex.org/keywords/occupational-exposure","display_name":"occupational exposure","score":0.48500001430511475},{"id":"https://openalex.org/keywords/environmental-exposure","display_name":"environmental exposure","score":0.5879999995231628},{"id":"https://openalex.org/keywords/antioxidant-defense","display_name":"antioxidant defense","score":0.43299999833106995}],"concepts":[{"id":"https://openalex.org/C21613296","wikidata":"https://www.wikidata.org/wiki/Q4925405","display_name":"Coagulative necrosis","level":2,"score":0.8268696069717407},{"id":"https://openalex.org/C2780159080","wikidata":"https://www.wikidata.org/wiki/Q1400536","display_name":"Intraperitoneal injection","level":2,"score":0.672282338142395},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5698299407958984},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5625529885292053},{"id":"https://openalex.org/C503630168","wikidata":"https://www.wikidata.org/wiki/Q178069","display_name":"Necrosis","level":2,"score":0.5333483219146729},{"id":"https://openalex.org/C2778054371","wikidata":"https://www.wikidata.org/wiki/Q503431","display_name":"Seminiferous tubule","level":4,"score":0.5278398990631104},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5195717811584473},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.4451681673526764},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.43559035658836365},{"id":"https://openalex.org/C2776390293","wikidata":"https://www.wikidata.org/wiki/Q2035485","display_name":"Subcutaneous injection","level":2,"score":0.41265034675598145},{"id":"https://openalex.org/C2779864607","wikidata":"https://www.wikidata.org/wiki/Q19720556","display_name":"Centrilobular necrosis","level":3,"score":0.4103847146034241},{"id":"https://openalex.org/C2781068068","wikidata":"https://www.wikidata.org/wiki/Q195614","display_name":"Sertoli cell","level":3,"score":0.33258405327796936},{"id":"https://openalex.org/C123765429","wikidata":"https://www.wikidata.org/wiki/Q36961","display_name":"Spermatogenesis","level":2,"score":0.24229666590690613}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007774","descriptor_name":"Lactation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007774","descriptor_name":"Lactation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014639","descriptor_name":"Vanadium","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D014639","descriptor_name":"Vanadium","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020011","descriptor_name":"Protective Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020011","descriptor_name":"Protective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmh:oai:ojshostng.com:article/1819","doi":null,"is_oa":true,"landing_page_url":"https://ojshostng.com/index.php/index/article/view/1819","pdf_url":null,"source":{"id":"https://openalex.org/S2764994983","display_name":"Nigerian Journal of Physiological Sciences","issn_l":"0794-859X","issn":["0794-859X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jpps-1","medline","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310321518","host_organization_name":"African Journals OnLine","host_organization_lineage":["https://openalex.org/P4310321518"],"host_organization_lineage_names":["African Journals OnLine"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0794-859X","raw_type":"info:eu-repo/semantics/article"},{"id":"pmid:26196578","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26196578","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria","raw_type":"Journal Article"},{"id":"pmh:cria:bioline:np:np14019","doi":null,"is_oa":false,"landing_page_url":"http://www.bioline.org.br/abstract?id=np14019","pdf_url":null,"source":{"id":"https://openalex.org/S4306402188","display_name":"Bioline International (Bioline International)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nigerian Journal of Physiological Sciences (ISSN: 0794-859X) Vol 29 Num 2","raw_type":"AA"},{"id":"mag:1900590072","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26196578","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:ojshostng.com:article/1819","doi":null,"is_oa":true,"landing_page_url":"https://ojshostng.com/index.php/index/article/view/1819","pdf_url":null,"source":{"id":"https://openalex.org/S2764994983","display_name":"Nigerian Journal of Physiological Sciences","issn_l":"0794-859X","issn":["0794-859X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jpps-1","medline","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310321518","host_organization_name":"African Journals OnLine","host_organization_lineage":["https://openalex.org/P4310321518"],"host_organization_lineage_names":["African Journals OnLine"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0794-859X","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1506149458","https://openalex.org/W1544024125","https://openalex.org/W1734082729","https://openalex.org/W1917582494","https://openalex.org/W1967474456","https://openalex.org/W1992194283","https://openalex.org/W1993181187","https://openalex.org/W2023953390","https://openalex.org/W2036636840","https://openalex.org/W2043388794","https://openalex.org/W2050219676","https://openalex.org/W2054514807","https://openalex.org/W2080174573","https://openalex.org/W2086661658","https://openalex.org/W2086997985","https://openalex.org/W2088010820","https://openalex.org/W2097034899","https://openalex.org/W2123733967","https://openalex.org/W2135976829","https://openalex.org/W2146430036","https://openalex.org/W2161115882","https://openalex.org/W2947532303"],"related_works":["https://openalex.org/W7100434993","https://openalex.org/W2146430036","https://openalex.org/W7039109336","https://openalex.org/W2036636840","https://openalex.org/W2748073124","https://openalex.org/W7100734960","https://openalex.org/W7065190111","https://openalex.org/W7062565646","https://openalex.org/W1994265035","https://openalex.org/W2321883293"],"abstract_inverted_index":{"The":[0,101],"work":[1],"investigated":[2],"the":[3,48,52,89,117,145,150,156,161,170,179,193,206,234],"protective":[4],"role":[5],"of":[6,16,23,41,51,72,85,116,126,137,149,155,169,196],"lactational":[7,188],"vitamin":[8,93,182,189,218],"E":[9,94,183,190,219],"administration":[10],"on":[11],"vanadium-induced":[12],"histotoxicity.":[13],"Three":[14],"groups":[15],"Wistar":[17],"rats,":[18],"with":[19,131,140],"each":[20],"group":[21,57,105],"comprising":[22],"two":[24],"dams":[25],"and":[26,123,128,135,153,166,198,208],"their":[27],"pups,":[28],"were":[29,37,68,81,176],"used":[30],"in":[31,65,133,178,205,217],"this":[32],"study.":[33],"Group":[34,66,78],"I":[35],"pups":[36,80,107],"administered":[38,69,82],"intraperitoneal":[39,70,83],"injection":[40,71,84],"sterile":[42],"water":[43],"at":[44,233],"volumes":[45],"corresponding":[46],"to":[47],"dose":[49],"rate":[50],"vanadium":[53,74,87,180,197],"(sodium":[54],"metavanadate)":[55],"treated":[56],"from":[58,75],"postnatal":[59],"day":[60],"(PND)":[61],"1-14":[62],"while":[63,88,160],"those":[64],"II":[67,106],"3mg/kg":[73,86],"PND":[76],"1-14.":[77],"III":[79],"dam":[90],"received":[91],"oral":[92],"(500":[95],"mg)":[96],"concurrently":[97],"every":[98],"72":[99],"hours.":[100],"results":[102],"showed":[103,147,163],"that":[104,187],"exhibited":[108],"histopathological":[109],"changes":[110,175],"which":[111],"included":[112],"seminiferous":[113],"tubule":[114],"disruption":[115,148],"testes":[118],"characterised":[119],"by":[120],"vacuolar":[121],"degeneration":[122,165],"coagulative":[124,167],"necrosis":[125,168],"spermatogonia":[127],"Sertoli":[129],"cells":[130],"reduction":[132],"mitosis,":[134],"areas":[136],"interstitial":[138],"thickening":[139],"fibroblast":[141],"proliferation.":[142],"In":[143],"addition,":[144],"lungs":[146],"bronchiolar":[151,157],"wall":[152],"denudation":[154],"respiratory":[158],"epithelium":[159],"liver":[162],"hydropic":[164],"centrilobular":[171],"hepatocytes.":[172],"These":[173],"histotoxic":[174,194],"ameliorated":[177],"+":[181],"group.":[184],"We":[185],"conclude":[186],"protects":[191],"against":[192],"effects":[195],"could":[199],"be":[200,215],"a":[201,231],"consideration":[202],"for":[203],"supplementation":[204,220],"occupationally":[207],"environmentally":[209],"exposed":[210],"neonates.":[211],"However,":[212],"caution":[213],"should":[214],"taken":[216],"because":[221],"there":[222],"is":[223],"still":[224],"equivocal":[225],"evidence":[226],"surrounding":[227],"its":[228],"benefits":[229],"as":[230],"supplement":[232],"moment.":[235]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":3}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}