{"id":"https://openalex.org/W1898299209","doi":"https://doi.org/10.1101/gad.14.1.17","title":"Essential role for Max in early embryonic growth and development","display_name":"Essential role for Max in early embryonic growth and development","publication_year":2000,"publication_date":"2000-01-01","ids":{"openalex":"https://openalex.org/W1898299209","doi":"https://doi.org/10.1101/gad.14.1.17","mag":"1898299209","pmid":"https://pubmed.ncbi.nlm.nih.gov/10640271","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/316346"},"language":"en","primary_location":{"id":"doi:10.1101/gad.14.1.17","doi":"https://doi.org/10.1101/gad.14.1.17","is_oa":true,"landing_page_url":"https://doi.org/10.1101/gad.14.1.17","pdf_url":"http://genesdev.cshlp.org/content/14/1/17.full.pdf","source":{"id":"https://openalex.org/S168778273","display_name":"Genes & Development","issn_l":"0890-9369","issn":["0890-9369","1549-5477"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes & Development","raw_type":"journal-article"},"volume":null,"type":"preprint","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://genesdev.cshlp.org/content/14/1/17.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019658625","display_name":"Hong Shen-Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I19772626","display_name":"Yeshiva University","ror":"https://ror.org/045x93337","country_code":"US","type":"education","lineage":["https://openalex.org/I19772626"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hong Shen-Li","raw_affiliation_strings":["Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","Yeshiva University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","institution_ids":["https://openalex.org/I129975664","https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Yeshiva University","institution_ids":["https://openalex.org/I19772626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020307190","display_name":"R\u00f3n\u00e1n C. O\u2019Hagan","orcid":"https://orcid.org/0009-0004-2112-101X","observed_orcids":["https://orcid.org/0009-0004-2112-101X"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R\u00f3n\u00e1n C. O'Hagan","raw_affiliation_strings":["Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","Dana Farber Cancer Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","institution_ids":["https://openalex.org/I129975664","https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Dana Farber Cancer Institute","institution_ids":["https://openalex.org/I4210117453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113671753","display_name":"Harry Hou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I19772626","display_name":"Yeshiva University","ror":"https://ror.org/045x93337","country_code":"US","type":"education","lineage":["https://openalex.org/I19772626"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harry Hou","raw_affiliation_strings":["Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","Yeshiva University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","institution_ids":["https://openalex.org/I129975664","https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Yeshiva University","institution_ids":["https://openalex.org/I19772626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025651085","display_name":"James W. Horner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James W. Horner","raw_affiliation_strings":["Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","Dana Farber Cancer Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","institution_ids":["https://openalex.org/I129975664","https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Dana Farber Cancer Institute","institution_ids":["https://openalex.org/I4210117453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082881561","display_name":"Han\u2010Woong Lee","orcid":"https://orcid.org/0000-0001-9515-3605","observed_orcids":["https://orcid.org/0000-0001-9515-3605","https://orcid.org/0000-0002-3555-0980"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I19772626","display_name":"Yeshiva University","ror":"https://ror.org/045x93337","country_code":"US","type":"education","lineage":["https://openalex.org/I19772626"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR","US"],"is_corresponding":false,"raw_author_name":"Han-Woong Lee","raw_affiliation_strings":["Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","Sungkyunkwan University","Yeshiva University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","institution_ids":["https://openalex.org/I129975664","https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Sungkyunkwan University","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Yeshiva University","institution_ids":["https://openalex.org/I19772626"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008120994","display_name":"Ronald Anthony DePinho","orcid":"https://orcid.org/0000-0002-5625-577X","observed_orcids":["https://orcid.org/0000-0002-5625-577X"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald A. DePinho","raw_affiliation_strings":["Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","Harvard University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461 USA;\n                           2Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115 USA; \n                           3Department of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts 02115 USA","institution_ids":["https://openalex.org/I129975664","https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Harvard University","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":100,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"1","first_page":"17","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/max","display_name":"Max","score":0.8299999833106995},{"id":"https://openalex.org/keywords/embryonic-development","display_name":"embryonic development","score":0.7799999713897705},{"id":"https://openalex.org/keywords/developmental-arrest","display_name":"developmental arrest","score":0.7950000166893005},{"id":"https://openalex.org/keywords/blastocyst-outgrowth","display_name":"blastocyst outgrowth","score":0.8510000109672546},{"id":"https://openalex.org/keywords/extraembryonic-tissues","display_name":"extraembryonic tissues","score":0.7760000228881836},{"id":"https://openalex.org/keywords/brdu-incorporation","display_name":"BrdU incorporation","score":0.7260000109672546},{"id":"https://openalex.org/keywords/mouse-embryo","display_name":"mouse embryo","score":0.5}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9416953325271606},{"id":"https://openalex.org/C2778177303","wikidata":"https://www.wikidata.org/wiki/Q227717","display_name":"Blastocyst","level":4,"score":0.7999883890151978},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.735371470451355},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.7128504514694214},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6669015288352966},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.6349892616271973},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.47059452533721924},{"id":"https://openalex.org/C92028520","wikidata":"https://www.wikidata.org/wiki/Q7395025","display_name":"SUPERFAMILY","level":3,"score":0.4417647421360016},{"id":"https://openalex.org/C105951970","wikidata":"https://www.wikidata.org/wiki/Q1036748","display_name":"Loss function","level":4,"score":0.4378730356693268},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4279303550720215},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.41080915927886963},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.3653014302253723},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3024272918701172},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.2757614254951477},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14791086316108704},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005314","descriptor_name":"Embryonic and Fetal Development","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020287","descriptor_name":"In Situ Nick-End Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050976","descriptor_name":"Basic-Leucine Zipper Transcription Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051778","descriptor_name":"Basic Helix-Loop-Helix Leucine Zipper Transcription Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1101/gad.14.1.17","doi":"https://doi.org/10.1101/gad.14.1.17","is_oa":true,"landing_page_url":"https://doi.org/10.1101/gad.14.1.17","pdf_url":"http://genesdev.cshlp.org/content/14/1/17.full.pdf","source":{"id":"https://openalex.org/S168778273","display_name":"Genes & Development","issn_l":"0890-9369","issn":["0890-9369","1549-5477"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes & Development","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:316346","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/316346","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes Dev","raw_type":"Text"},{"id":"pmid:10640271","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10640271","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes & development","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1101/gad.14.1.17","doi":"https://doi.org/10.1101/gad.14.1.17","is_oa":true,"landing_page_url":"https://doi.org/10.1101/gad.14.1.17","pdf_url":"http://genesdev.cshlp.org/content/14/1/17.full.pdf","source":{"id":"https://openalex.org/S168778273","display_name":"Genes & Development","issn_l":"0890-9369","issn":["0890-9369","1549-5477"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes & Development","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1972781834","display_name":"REGULATION OF MYC NETWORK FUNCTION IN DEVELOPMENT","funder_award_id":"5r01hd028317-05","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2542423042","display_name":"MOLECULAR GENETICS OF LENS AND CATARACT DEVELOPMENT","funder_award_id":"5r01ey009300-10","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2786049298","display_name":null,"funder_award_id":"R01EY09300","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G6733923751","display_name":null,"funder_award_id":"R01 HD28317","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G9000877850","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA013330","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000911608","display_name":"Dana-Farber/Harvard Cancer Center","funder_award_id":"P30CA006516","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G918485426","display_name":null,"funder_award_id":"5-P30 CA06516","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1898299209.pdf","grobid_xml":"https://content.openalex.org/works/W1898299209.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W209857828","https://openalex.org/W1502418486","https://openalex.org/W1509850974","https://openalex.org/W1549051606","https://openalex.org/W1560485148","https://openalex.org/W1770334357","https://openalex.org/W1861123116","https://openalex.org/W1887854518","https://openalex.org/W1953035097","https://openalex.org/W1966286195","https://openalex.org/W1968710429","https://openalex.org/W1969117475","https://openalex.org/W1972394744","https://openalex.org/W1975489321","https://openalex.org/W1980110416","https://openalex.org/W1981391513","https://openalex.org/W1984903030","https://openalex.org/W1994600118","https://openalex.org/W2010745413","https://openalex.org/W2028701813","https://openalex.org/W2047277868","https://openalex.org/W2049114614","https://openalex.org/W2051970761","https://openalex.org/W2059560408","https://openalex.org/W2072469348","https://openalex.org/W2082657038","https://openalex.org/W2085213714","https://openalex.org/W2097774235","https://openalex.org/W2102532208","https://openalex.org/W2102614730","https://openalex.org/W2118862408","https://openalex.org/W2119368674","https://openalex.org/W2124330611","https://openalex.org/W2130760866","https://openalex.org/W2163307259","https://openalex.org/W2402107217","https://openalex.org/W2413112814","https://openalex.org/W2433014878","https://openalex.org/W2468496770","https://openalex.org/W2979237768","https://openalex.org/W4236512674","https://openalex.org/W4254480971","https://openalex.org/W6641776850","https://openalex.org/W6718014892"],"related_works":["https://openalex.org/W2003916413","https://openalex.org/W7027939352","https://openalex.org/W2152133635","https://openalex.org/W2049128910","https://openalex.org/W3129355644","https://openalex.org/W2095054048","https://openalex.org/W2132740145","https://openalex.org/W2022698393","https://openalex.org/W2169614179","https://openalex.org/W2475872962"],"abstract_inverted_index":{"Loss":[0],"of":[1,12,28,78,92],"Max":[2,30,60,79],"function":[3,88],"in":[4,8,32,36,39,42,49,70,81],"the":[5,33,64],"mouse":[6],"resulted":[7],"generalized":[9],"developmental":[10],"arrest":[11],"both":[13],"embryonic":[14],"and":[15,38,51,56,74],"extraembryonic":[16],"tissues":[17],"at":[18],"early":[19,71],"postimplantation":[20],"(approximately":[21],"E5.5-6.5),":[22],"coincident":[23],"with":[24],"loss":[25],"or":[26],"dilution":[27],"maternal":[29,76],"stores":[31],"expanding":[34],"embryo":[35],"vivo":[37],"blastocyst":[40],"outgrowths":[41],"vitro.":[43],"Developmentally":[44],"arrested":[45],"embryos":[46],"were":[47],"reduced":[48],"size":[50],"exhibited":[52],"widespread":[53],"cytological":[54],"degeneration":[55],"feeble":[57],"BrdU":[58],"incorporation.":[59],"and,":[61],"by":[62],"extension,":[63],"Myc":[65,86],"superfamily,":[66],"serve":[67],"essential":[68],"roles":[69],"mammalian":[72],"development":[73],"a":[75],"reservoir":[77],"exists":[80],"sufficient":[82],"amount":[83],"to":[84],"sustain":[85],"superfamily":[87],"through":[89],"preimplantation":[90],"stages":[91],"development.":[93]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}