{"id":"https://openalex.org/W1893982012","doi":"https://doi.org/10.1093/clinchem/22.8.1378","title":"Measurement of glucose in plasma, with use of immobilized glucose oxidase and peroxidase.","display_name":"Measurement of glucose in plasma, with use of immobilized glucose oxidase and peroxidase.","publication_year":1976,"publication_date":"1976-08-01","ids":{"openalex":"https://openalex.org/W1893982012","doi":"https://doi.org/10.1093/clinchem/22.8.1378","mag":"1893982012","pmid":"https://pubmed.ncbi.nlm.nih.gov/949848"},"language":"en","primary_location":{"id":"doi:10.1093/clinchem/22.8.1378","doi":"https://doi.org/10.1093/clinchem/22.8.1378","is_oa":false,"landing_page_url":"https://doi.org/10.1093/clinchem/22.8.1378","pdf_url":null,"source":{"id":"https://openalex.org/S139212996","display_name":"Clinical Chemistry","issn_l":"0009-9147","issn":["0009-9147","1530-8561"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320272","host_organization_name":"American Association for Clinical Chemistry","host_organization_lineage":["https://openalex.org/P4310320272"],"host_organization_lineage_names":["American Association for Clinical Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066325307","display_name":"Shiow-ling W Kiang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S W Kiang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065538290","display_name":"Jui\u2010Chang W. Kuan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J W Kuan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113600161","display_name":"Shia S. Kuan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S S Kuan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5108804011","display_name":"George G. Guilbault","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G G Guilbault","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4636,"currency":"USD","value_usd":4636},"apc_paid":null,"fwci":1.3074,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.76386564,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"22","issue":"8","first_page":"1378","last_page":"1382"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.6855000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.6855000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.1468999981880188,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.08389999717473984,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasma-glucose","display_name":"plasma glucose","score":0.7099999785423279},{"id":"https://openalex.org/keywords/glucose-oxidase","display_name":"glucose oxidase","score":0.7329999804496765},{"id":"https://openalex.org/keywords/peroxidase","display_name":"peroxidase","score":0.8399999737739563},{"id":"https://openalex.org/keywords/immobilized-enzymes","display_name":"immobilized enzymes","score":0.9200000166893005},{"id":"https://openalex.org/keywords/fluorometric-assay","display_name":"fluorometric assay","score":0.9340000152587891},{"id":"https://openalex.org/keywords/magnetic-stirrer","display_name":"magnetic stirrer","score":0.8700000047683716},{"id":"https://openalex.org/keywords/enzyme-stability","display_name":"enzyme stability","score":0.5669999718666077},{"id":"https://openalex.org/keywords/uric-acid","display_name":"uric acid","score":0.9670000076293945},{"id":"https://openalex.org/keywords/creatinine","display_name":"creatinine","score":0.7929999828338623},{"id":"https://openalex.org/keywords/hexokinase-method","display_name":"hexokinase method","score":0.9959999918937683}],"concepts":[{"id":"https://openalex.org/C2777197210","wikidata":"https://www.wikidata.org/wiki/Q419321","display_name":"Glucose oxidase","level":3,"score":0.8923372030258179},{"id":"https://openalex.org/C162008176","wikidata":"https://www.wikidata.org/wiki/Q419305","display_name":"Peroxidase","level":3,"score":0.8049256205558777},{"id":"https://openalex.org/C3020574416","wikidata":"https://www.wikidata.org/wiki/Q275157","display_name":"Plasma glucose","level":3,"score":0.7068714499473572},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5188154578208923},{"id":"https://openalex.org/C82706917","wikidata":"https://www.wikidata.org/wiki/Q10251","display_name":"Plasma","level":2,"score":0.4332350492477417},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.39739522337913513},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3958320915699005},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.2924502491950989},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.28616514801979065},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2555932402610779},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.16798582673072815},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001234","descriptor_name":"Aspergillus niger","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D001322","descriptor_name":"Autoanalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D005069","descriptor_name":"Evaluation Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005949","descriptor_name":"Glucose Oxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006719","descriptor_name":"Homovanillic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006735","descriptor_name":"Horseradish Peroxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008722","descriptor_name":"Methods","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010544","descriptor_name":"Peroxidases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013050","descriptor_name":"Spectrometry, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/clinchem/22.8.1378","doi":"https://doi.org/10.1093/clinchem/22.8.1378","is_oa":false,"landing_page_url":"https://doi.org/10.1093/clinchem/22.8.1378","pdf_url":null,"source":{"id":"https://openalex.org/S139212996","display_name":"Clinical Chemistry","issn_l":"0009-9147","issn":["0009-9147","1530-8561"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320272","host_organization_name":"American Association for Clinical Chemistry","host_organization_lineage":["https://openalex.org/P4310320272"],"host_organization_lineage_names":["American Association for Clinical Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry","raw_type":"journal-article"},{"id":"pmid:949848","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/949848","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4206008797","https://openalex.org/W2049134256","https://openalex.org/W2076920822","https://openalex.org/W2417355268","https://openalex.org/W2026557087","https://openalex.org/W2067183778","https://openalex.org/W1959561623","https://openalex.org/W2082842824","https://openalex.org/W2085751671","https://openalex.org/W2030516663"],"abstract_inverted_index":{"We":[0],"describe":[1],"a":[2],"novel":[3],"fluorometric":[4],"technique":[5,86],"for":[6,101,108],"simple,":[7],"rapid,":[8],"and":[9,20,35,56,63,87,104,113],"economical":[10],"assay":[11,74],"of":[12,16,60,72,80],"glucose":[13,18,81],"by":[14,84,88],"use":[15],"immobilized":[17,32,97],"oxidase":[19],"peroxidase.":[21],"A":[22],"cylindrical":[23],"magnetic":[24],"stirrer":[25],"was":[26,75],"specially":[27],"designed":[28],"to":[29,36,77],"hold":[30],"the":[31,38,73,89],"enzymes":[33,98],"firmly":[34],"allow":[37],"reaction":[39],"minzymic":[40],"transformation":[41],"quickly.":[42],"Blood":[43],"plasma":[44],"can":[45,105],"be":[46,106],"assayed":[47],"directly":[48],"with":[49],"no":[50],"pretreatment.":[51],"Ascrobic":[52],"acid,":[53,55],"uric":[54],"creatinine":[57],"in":[58],"concenctrations":[59],"0.25,":[61,62],"0.2":[64],"g/liter,":[65],"respectively,":[66],"did":[67],"not":[68],"interfere.":[69],"The":[70,96],"linearity":[71],"extended":[76],"4.0":[78],"g":[79],"concentrations.":[82],"Results":[83],"our":[85],"otoluidine":[90],"or":[91],"hexokinase":[92],"methods":[93],"agreed":[94],"well.":[95],"are":[99],"stable":[100],"several":[102,109],"months":[103],"used":[107],"hundred":[110],"highly":[111],"accurate":[112],"reproducible":[114],"assays.":[115]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}