{"id":"https://openalex.org/W1893072959","doi":null,"title":"Causes of death in renal transplant recipients: a study of 102 autopsies from 1968 to 1991.","display_name":"Causes of death in renal transplant recipients: a study of 102 autopsies from 1968 to 1991.","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W1893072959","mag":"1893072959","pmid":"https://pubmed.ncbi.nlm.nih.gov/7884765","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1295069"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:206733","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1295069","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC1295069","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008230762","display_name":"Marlene Ant\u00f4nia dos Reis","orcid":"https://orcid.org/0000-0003-2523-2097","observed_orcids":["https://orcid.org/0000-0003-2523-2097"]},"institutions":[{"id":"https://openalex.org/I4210106570","display_name":"Universidade Federal do Tri\u00e2ngulo Mineiro","ror":"https://ror.org/01av3m334","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210106570"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"M A Reis","raw_affiliation_strings":["Department of General Pathology, Faculty of Medicine of Tri\u00e2ngulo Mineiro, Uberaba, MG"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Pathology, Faculty of Medicine of Tri\u00e2ngulo Mineiro, Uberaba, MG","institution_ids":["https://openalex.org/I4210106570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036230248","display_name":"Roberto Silva Costa","orcid":"https://orcid.org/0000-0003-3639-0189","observed_orcids":["https://orcid.org/0000-0003-3639-0189"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R S Costa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103834637","display_name":"Agenor Spallini Ferraz","orcid":"https://orcid.org/0009-0004-9578-5206","observed_orcids":["https://orcid.org/0009-0004-9578-5206"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A S Ferraz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.0253,"has_fulltext":false,"cited_by_count":90,"citation_normalized_percentile":{"value":0.94722955,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"88","issue":"1","first_page":"24","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9707000255584717,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9707000255584717,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11163","display_name":"Organ Donation and Transplantation","score":0.006899999920278788,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kidney-transplant-recipients","display_name":"kidney transplant recipients","score":0.8149999976158142},{"id":"https://openalex.org/keywords/causes-of-death","display_name":"causes of death","score":0.8849999904632568},{"id":"https://openalex.org/keywords/post-transplant-infection","display_name":"post-transplant infection","score":0.6819999814033508},{"id":"https://openalex.org/keywords/disseminated-infection","display_name":"disseminated infection","score":0.6949999928474426},{"id":"https://openalex.org/keywords/pneumonia","display_name":"pneumonia","score":0.8410000205039978},{"id":"https://openalex.org/keywords/acute-pyelonephritis","display_name":"acute pyelonephritis","score":0.9629999995231628},{"id":"https://openalex.org/keywords/fungal-infection","display_name":"fungal infection","score":0.6110000014305115},{"id":"https://openalex.org/keywords/cryptococcus","display_name":"Cryptococcus","score":0.8100000023841858},{"id":"https://openalex.org/keywords/pneumocystis-carinii","display_name":"Pneumocystis carinii","score":0.843999981880188},{"id":"https://openalex.org/keywords/herpes-simplex-virus","display_name":"herpes simplex virus","score":0.7689999938011169},{"id":"https://openalex.org/keywords/cytomegalovirus","display_name":"cytomegalovirus","score":0.9480000138282776},{"id":"https://openalex.org/keywords/graft-rejection","display_name":"graft rejection","score":0.7160000205039978},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.75},{"id":"https://openalex.org/keywords/autopsy-findings","display_name":"autopsy findings","score":0.5370000004768372}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6752036809921265},{"id":"https://openalex.org/C2993443204","wikidata":"https://www.wikidata.org/wiki/Q134478","display_name":"Pneumocystis carinii","level":4,"score":0.6299377679824829},{"id":"https://openalex.org/C2779504383","wikidata":"https://www.wikidata.org/wiki/Q41482","display_name":"Autopsy","level":2,"score":0.5313891172409058},{"id":"https://openalex.org/C29374701","wikidata":"https://www.wikidata.org/wiki/Q1931388","display_name":"Cause of death","level":3,"score":0.506646454334259},{"id":"https://openalex.org/C2779448432","wikidata":"https://www.wikidata.org/wiki/Q135175","display_name":"Nocardia","level":3,"score":0.45690006017684937},{"id":"https://openalex.org/C2779196057","wikidata":"https://www.wikidata.org/wiki/Q835718","display_name":"Opportunistic infection","level":4,"score":0.44147711992263794},{"id":"https://openalex.org/C2909201284","wikidata":"https://www.wikidata.org/wiki/Q835718","display_name":"AIDS-Related Opportunistic Infections","level":5,"score":0.42799991369247437},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41263580322265625},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.4064411222934723},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3560641407966614},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.33192309737205505},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3104197680950165},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23992487788200378},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.22892844676971436},{"id":"https://openalex.org/C2777559004","wikidata":"https://www.wikidata.org/wiki/Q134478","display_name":"Pneumocystis jirovecii","level":3,"score":0.20432281494140625},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.18624764680862427},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.16722503304481506},{"id":"https://openalex.org/C2776452011","wikidata":"https://www.wikidata.org/wiki/Q311463","display_name":"Sida","level":4,"score":0.15502148866653442},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001344","descriptor_name":"Autopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D002423","descriptor_name":"Cause of Death","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005767","descriptor_name":"Gastrointestinal Diseases","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007165","descriptor_name":"Immunosuppression Therapy","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009894","descriptor_name":"Opportunistic Infections","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true}],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:206733","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1295069","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:7884765","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7884765","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Royal Society of Medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1295069","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1295069/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J R Soc Med","raw_type":"Text"},{"id":"mag:1893072959","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7884765","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:206733","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1295069","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W2014273647","https://openalex.org/W2014976706","https://openalex.org/W2047688396","https://openalex.org/W2049219987","https://openalex.org/W2049496890","https://openalex.org/W2051281491","https://openalex.org/W2079378902","https://openalex.org/W2091218086","https://openalex.org/W2238879922","https://openalex.org/W2323841893","https://openalex.org/W2399292310","https://openalex.org/W2406918002","https://openalex.org/W2412573535","https://openalex.org/W2462969968","https://openalex.org/W4290214810"],"related_works":["https://openalex.org/W2412573535","https://openalex.org/W218775925","https://openalex.org/W2060608300","https://openalex.org/W2265333498","https://openalex.org/W2028388165","https://openalex.org/W2047850053","https://openalex.org/W1877296918","https://openalex.org/W2442434723","https://openalex.org/W1486186956","https://openalex.org/W7095407709"],"abstract_inverted_index":{"A":[0],"study":[1],"was":[2,45,159,168,175],"conducted":[3],"on":[4,36],"102":[5],"patients":[6,90,102,166,183],"submitted":[7],"to":[8,29,47,196],"renal":[9,186],"transplant":[10,187],"who":[11],"died":[12],"and":[13,42,64,117,128,136,152,167],"were":[14],"autopsied":[15],"at":[16],"the":[17,50,68,97,162,197],"University":[18],"Hospital,":[19],"Faculty":[20],"of":[21,23,33,39,49,71,164],"Medicine":[22],"Ribeir\u00e3o":[24],"Preto,":[25],"Brazil,":[26],"from":[27],"1968":[28],"1991.":[30],"The":[31,104],"cause":[32],"death,":[34],"based":[35],"a":[37],"review":[38],"medical":[40],"records":[41],"autopsy":[43],"reports,":[44],"assigned":[46],"one":[48],"following":[51],"categories:":[52],"infectious":[53],"(69.6%);":[54],"cardiovascular":[55],"(12.7%);":[56],"gastrointestinal":[57],"(7.8%);":[58],"graft":[59],"rejection":[60],"(6.9%);":[61],"tumoral":[62],"(2.0%);":[63],"undetermined":[65],"(1.0%).":[66],"Among":[67],"71":[69],"cases":[70],"death":[72,173],"caused":[73],"by":[74,93,123,144],"infection,":[75],"28":[76],"(39.4%)":[77],"showed":[78],"disseminated":[79],"agents":[80,107],"involving":[81],"two":[82],"or":[83],"more":[84],"organs.":[85],"Isolated":[86],"pneumonia":[87],"involved":[88],"17":[89],"(23.9%),":[91],"followed":[92],"acute":[94],"pyelonephritis":[95],"in":[96,100,161],"transplanted":[98],"kidney":[99],"10":[101],"(14.1%).":[103],"most":[105],"frequent":[106],"were:":[108],"bacteria":[109],"(58.0%),":[110],"divided":[111],"into":[112],"'non-classified'":[113],"(83.0%),":[114],"Nocardia":[115],"(10.6%)":[116],"Mycobacterium":[118],"(6.4%);":[119],"fungi":[120],"(27.5%)":[121],"represented":[122,143],"Cryptococcus":[124],"(22.7%),":[125],"Aspergillus,":[126],"Candida":[127],"Pneumocystis":[129],"carinii":[130],"(18.1%":[131],"each),":[132],"Histoplasma":[133],"(13.6%),":[134],"Mucor":[135],"Paracoccidioides":[137],"brasiliensis":[138],"(4.5%":[139],"each);":[140],"viruses":[141],"(6.2%)":[142],"Herpes":[145],"simplex":[146],"(60.0%);":[147],"metazoa":[148],"(5.0%,":[149],"S.":[150],"stercoralis),":[151],"protozoa":[153],"(2.5%,":[154],"T.":[155],"cruzi).":[156],"Cytomegalovirus":[157],"(CMV)":[158],"identified":[160],"lungs":[163],"12":[165],"not":[169],"directly":[170],"correlated":[171],"with":[172,177],"but":[174],"associated":[176],"other":[178],"agents.":[179],"In":[180],"conclusion,":[181],"immunodepressed":[182],"such":[184],"as":[185],"recipients":[188],"should":[189],"be":[190],"carefully":[191],"monitored":[192],"for":[193],"infection":[194],"due":[195],"high":[198],"mortality":[199],"rate.":[200]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}