{"id":"https://openalex.org/W1892962033","doi":"https://doi.org/10.1039/c5sc01402f","title":"A fully synthetic self-adjuvanting globo H-Based vaccine elicited strong T cell-mediated antitumor immunity","display_name":"A fully synthetic self-adjuvanting globo H-Based vaccine elicited strong T cell-mediated antitumor immunity","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W1892962033","doi":"https://doi.org/10.1039/c5sc01402f","mag":"1892962033","pmid":"https://pubmed.ncbi.nlm.nih.gov/26918109","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4762603"},"language":"en","primary_location":{"id":"doi:10.1039/c5sc01402f","doi":"https://doi.org/10.1039/c5sc01402f","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c5sc01402f","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2015/sc/c5sc01402f","source":{"id":"https://openalex.org/S184645833","display_name":"Chemical Science","issn_l":"2041-6520","issn":["2041-6520","2041-6539"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-3","ki-jl-2","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://pubs.rsc.org/en/content/articlepdf/2015/sc/c5sc01402f","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031295790","display_name":"Zhifang Zhou","orcid":"https://orcid.org/0000-0002-4703-2320","observed_orcids":["https://orcid.org/0000-0002-4703-2320"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhifang Zhou","raw_affiliation_strings":["Department of Chemistry","Detroit","USA","Wayne State University","Department of Chemistry, Wayne State University, 1501 Cass Avenue, Detroit, Michigan 48202, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry","institution_ids":[]},{"raw_affiliation_string":"Detroit","institution_ids":[]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Wayne State University","institution_ids":["https://openalex.org/I185443292"]},{"raw_affiliation_string":"Department of Chemistry, Wayne State University, 1501 Cass Avenue, Detroit, Michigan 48202, United States","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048423176","display_name":"Guochao Liao","orcid":"https://orcid.org/0000-0001-6112-5040","observed_orcids":["https://orcid.org/0000-0001-6112-5040"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guochao Liao","raw_affiliation_strings":["Department of Chemistry","Detroit","USA","Wayne State University","Department of Chemistry, Wayne State University, 1501 Cass Avenue,Detroit,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry","institution_ids":[]},{"raw_affiliation_string":"Detroit","institution_ids":[]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Wayne State University","institution_ids":["https://openalex.org/I185443292"]},{"raw_affiliation_string":"Department of Chemistry, Wayne State University, 1501 Cass Avenue,Detroit,USA","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113873578","display_name":"Satadru Sekhar Mandal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Satadru S. Mandal","raw_affiliation_strings":["Department of Chemistry","Detroit","USA","Wayne State University","Department of Chemistry, Wayne State University, 1501 Cass Avenue,Detroit,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry","institution_ids":[]},{"raw_affiliation_string":"Detroit","institution_ids":[]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Wayne State University","institution_ids":["https://openalex.org/I185443292"]},{"raw_affiliation_string":"Department of Chemistry, Wayne State University, 1501 Cass Avenue,Detroit,USA","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060040819","display_name":"Sharad Suryawanshi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sharad Suryawanshi","raw_affiliation_strings":["Department of Chemistry","Detroit","USA","Wayne State University","Department of Chemistry, Wayne State University, 1501 Cass Avenue,Detroit,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry","institution_ids":[]},{"raw_affiliation_string":"Detroit","institution_ids":[]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Wayne State University","institution_ids":["https://openalex.org/I185443292"]},{"raw_affiliation_string":"Department of Chemistry, Wayne State University, 1501 Cass Avenue,Detroit,USA","institution_ids":["https://openalex.org/I185443292"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051316812","display_name":"Zhongwu Guo","orcid":"https://orcid.org/0000-0001-5302-6456","observed_orcids":["https://orcid.org/0000-0001-5302-6456"]},"institutions":[{"id":"https://openalex.org/I185443292","display_name":"Wayne State University","ror":"https://ror.org/01070mq45","country_code":"US","type":"education","lineage":["https://openalex.org/I185443292"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Zhongwu Guo","raw_affiliation_strings":["Department of Chemistry","Detroit","USA","Wayne State University","Department of Chemistry, Wayne State University, 1501 Cass Avenue,Detroit,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry","institution_ids":[]},{"raw_affiliation_string":"Detroit","institution_ids":[]},{"raw_affiliation_string":"USA","institution_ids":[]},{"raw_affiliation_string":"Wayne State University","institution_ids":["https://openalex.org/I185443292"]},{"raw_affiliation_string":"Department of Chemistry, Wayne State University, 1501 Cass Avenue,Detroit,USA","institution_ids":["https://openalex.org/I185443292"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5051316812"],"corresponding_institution_ids":["https://openalex.org/I185443292"],"apc_list":null,"apc_paid":null,"fwci":3.2482,"has_fulltext":true,"cited_by_count":85,"citation_normalized_percentile":{"value":0.9271672,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"6","issue":"12","first_page":"7112","last_page":"7121"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.6753000020980835,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.6753000020980835,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.2549000084400177,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.06260000169277191,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cancer-vaccines","display_name":"cancer vaccines","score":0.7360000014305115},{"id":"https://openalex.org/keywords/self-adjuvanting-vaccine","display_name":"self-adjuvanting vaccine","score":0.8169999718666077},{"id":"https://openalex.org/keywords/monophosphoryl-lipid-a","display_name":"monophosphoryl lipid A","score":0.9589999914169312},{"id":"https://openalex.org/keywords/glycoconjugate-vaccines","display_name":"glycoconjugate vaccines","score":0.8880000114440918},{"id":"https://openalex.org/keywords/t-cell-mediated-immunity","display_name":"T cell immunity","score":0.8669999837875366},{"id":"https://openalex.org/keywords/t-cell-dependent-immune-response","display_name":"T cell-dependent immunity","score":0.718999981880188},{"id":"https://openalex.org/keywords/igg1-antibody-response","display_name":"IgG1 antibody response","score":0.8360000252723694},{"id":"https://openalex.org/keywords/complement-dependent-cytotoxicity","display_name":"complement-dependent cytotoxicity","score":0.968999981880188},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.7979999780654907},{"id":"https://openalex.org/keywords/keyhole-limpet-hemocyanin","display_name":"keyhole limpet hemocyanin","score":0.8489999771118164},{"id":"https://openalex.org/keywords/tumor-associated-glycans","display_name":"tumor-associated glycans","score":0.722000002861023}],"concepts":[{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.6902302503585815},{"id":"https://openalex.org/C197336794","wikidata":"https://www.wikidata.org/wiki/Q5161150","display_name":"Conjugate","level":2,"score":0.5450106859207153},{"id":"https://openalex.org/C3020653616","wikidata":"https://www.wikidata.org/wiki/Q189146","display_name":"Cell mediated immunity","level":4,"score":0.4395086467266083},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4279747009277344},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.3389071822166443},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31371843814849854},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1039/c5sc01402f","doi":"https://doi.org/10.1039/c5sc01402f","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c5sc01402f","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2015/sc/c5sc01402f","source":{"id":"https://openalex.org/S184645833","display_name":"Chemical Science","issn_l":"2041-6520","issn":["2041-6520","2041-6539"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-3","ki-jl-2","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Science","raw_type":"journal-article"},{"id":"pmid:26918109","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26918109","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical science","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4762603","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4762603/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chem Sci","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1039/c5sc01402f","doi":"https://doi.org/10.1039/c5sc01402f","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c5sc01402f","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2015/sc/c5sc01402f","source":{"id":"https://openalex.org/S184645833","display_name":"Chemical Science","issn_l":"2041-6520","issn":["2041-6520","2041-6539"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-3","ki-jl-2","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Science","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1278770830","display_name":null,"funder_award_id":"P30 CA022453","funder_id":"https://openalex.org/F4320317266","funder_display_name":"Barbara Ann Karmanos Cancer Institute"},{"id":"https://openalex.org/G2425540664","display_name":null,"funder_award_id":"P30 CA022453","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7430570504","display_name":"Acquisition of a Cyber-Enabled 600 MHz NMR Spectrometer for Research and Teaching","funder_award_id":"0840413","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8103822784","display_name":"Metabolic Engineering of Cancer for Selective Immunotargeting (NIH/NCI: 5R01CA095142-14)","funder_award_id":"R01CA095142","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000905662","display_name":"CANCER CENTER SUPPORT GRANT","funder_award_id":"P30CA022453","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320309272","display_name":"Wayne State University","ror":"https://ror.org/01070mq45"},{"id":"https://openalex.org/F4320317266","display_name":"Barbara Ann Karmanos Cancer Institute","ror":"https://ror.org/00ee40h97"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337393","display_name":"Division of Chemistry","ror":"https://ror.org/01ar8dr59"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1892962033.pdf","grobid_xml":"https://content.openalex.org/works/W1892962033.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W399092470","https://openalex.org/W581670567","https://openalex.org/W1518310590","https://openalex.org/W1569852946","https://openalex.org/W1593582113","https://openalex.org/W1672501298","https://openalex.org/W1963617213","https://openalex.org/W1964243035","https://openalex.org/W1971270966","https://openalex.org/W1971353492","https://openalex.org/W1976760334","https://openalex.org/W1982895831","https://openalex.org/W1983073871","https://openalex.org/W1991676798","https://openalex.org/W2018453381","https://openalex.org/W2019479596","https://openalex.org/W2021911250","https://openalex.org/W2023990508","https://openalex.org/W2024809403","https://openalex.org/W2025689119","https://openalex.org/W2026813736","https://openalex.org/W2035096211","https://openalex.org/W2037466942","https://openalex.org/W2038270516","https://openalex.org/W2044535505","https://openalex.org/W2046667705","https://openalex.org/W2053085424","https://openalex.org/W2054183568","https://openalex.org/W2054254905","https://openalex.org/W2054476963","https://openalex.org/W2054646347","https://openalex.org/W2059675969","https://openalex.org/W2061202275","https://openalex.org/W2069825381","https://openalex.org/W2069891967","https://openalex.org/W2072347337","https://openalex.org/W2077432635","https://openalex.org/W2077547071","https://openalex.org/W2078731100","https://openalex.org/W2082718424","https://openalex.org/W2083515629","https://openalex.org/W2092591554","https://openalex.org/W2092795404","https://openalex.org/W2098315731","https://openalex.org/W2108471741","https://openalex.org/W2121229568","https://openalex.org/W2123501358","https://openalex.org/W2127934565","https://openalex.org/W2130655121","https://openalex.org/W2136383144","https://openalex.org/W2138101780","https://openalex.org/W2147365150","https://openalex.org/W2150484311","https://openalex.org/W2152916164","https://openalex.org/W2163670729","https://openalex.org/W2165001335","https://openalex.org/W2167991675","https://openalex.org/W2171217845","https://openalex.org/W2227399362","https://openalex.org/W2296221004","https://openalex.org/W2323853830","https://openalex.org/W3127349307","https://openalex.org/W4234317413","https://openalex.org/W4313379446"],"related_works":["https://openalex.org/W2750701643","https://openalex.org/W4405420744","https://openalex.org/W3161438163","https://openalex.org/W2019479596","https://openalex.org/W2044535505","https://openalex.org/W2317274483","https://openalex.org/W4412672832","https://openalex.org/W2080655915","https://openalex.org/W2035096211","https://openalex.org/W7215160915"],"abstract_inverted_index":{"Therapeutic":[0],"cancer":[1,10,43,60,174,190],"vaccines":[2,47],"based":[3],"on":[4,9,38],"the":[5,14,27,68,118,131,158,178,183,193],"abnormal":[6],"glycans":[7],"expressed":[8],"cells,":[11],"such":[12,46,51],"as":[13,41,52],"globo":[15,34,79,119,171,184,194],"H":[16,35,80],"antigen,":[17],"have":[18,48,180],"witnessed":[19],"great":[20],"progress":[21],"in":[22,54,59],"recent":[23],"years.":[24],"For":[25],"example,":[26],"keyhole":[28],"limpet":[29],"hemocyanin":[30],"(KLH)":[31],"conjugate":[32,186,196],"of":[33,78,133,177],"has":[36],"been":[37],"clinical":[39],"trials":[40],"a":[42,70,142,147,188],"vaccine.":[44],"However,":[45],"intrinsic":[49],"problems,":[50],"inconsistence":[53],"eliciting":[55],"T":[56,100],"cell-mediated":[57],"immunity":[58],"patients":[61],"and":[62,81,99,109,113,165,200,205],"difficult":[63],"quality":[64],"control.":[65],"To":[66],"address":[67],"issue,":[69],"structurally":[71],"defined":[72],"fully":[73],"synthetic":[74],"glycoconjugate":[75],"vaccine":[76,90,143,160,191],"composed":[77],"monophosphoryl":[82],"lipid":[83],"A":[84],"(MPLA)":[85],"was":[86,91,124,139,151],"developed.":[87],"The":[88],"new":[89,159],"shown":[92],"to":[93,164,170],"elicit":[94],"robust":[95],"IgG1":[96],"antibody":[97],"responses":[98,116,129],"cell-dependent":[101],"immunity,":[102],"which":[103],"is":[104,187,201],"desired":[105],"for":[106],"anticancer":[107],"vaccine,":[108],"induce":[110],"significantly":[111],"faster":[112],"stronger":[114],"immune":[115,128],"than":[117,192],"H-KLH":[120,195],"conjugate.":[121],"Moreover,":[122],"it":[123],"self-adjuvanting,":[125],"namely,":[126],"inducing":[127],"without":[130],"use":[132],"an":[134],"external":[135],"adjuvant,":[136],"thus":[137],"MPLA":[138],"not":[140],"only":[141],"carrier":[144],"but":[145],"also":[146,152],"build-in":[148],"adjuvant.":[149],"It":[150],"found":[153],"that":[154,182],"antibodies":[155],"induced":[156],"by":[157],"could":[161],"selectively":[162],"bind":[163],"mediate":[166],"strong":[167],"complement-dependent":[168],"cytotoxicity":[169],"H-expressing":[172],"MCF-7":[173],"cell.":[175],"All":[176],"results":[179],"demonstrated":[181],"H-MPLA":[185],"better":[189],"under":[197],"experimental":[198],"conditions":[199],"worth":[202],"further":[203],"investigation":[204],"development.":[206]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":6}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
