{"id":"https://openalex.org/W189019077","doi":null,"title":"Gain weight by \"going diet?\" Artificial sweeteners and the neurobiology of sugar cravings: Neuroscience 2010.","display_name":"Gain weight by \"going diet?\" Artificial sweeteners and the neurobiology of sugar cravings: Neuroscience 2010.","publication_year":2010,"publication_date":"2010-06-01","ids":{"openalex":"https://openalex.org/W189019077","mag":"189019077","pmid":"https://pubmed.ncbi.nlm.nih.gov/20589192","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2892765"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2892765","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2892765","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yale J Biol Med","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2892765","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101545579","display_name":"Qing H. Yang","orcid":"https://orcid.org/0009-0001-1481-5265","observed_orcids":["https://orcid.org/0009-0001-1481-5265"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Qing Yang","raw_affiliation_strings":["Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06511, USA. qing.yang@yale.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06511, USA. qing.yang@yale.edu","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5101545579"],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":null,"apc_paid":null,"fwci":9.3811,"has_fulltext":false,"cited_by_count":263,"citation_normalized_percentile":{"value":0.98405606,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"83","issue":"2","first_page":"101","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11584","display_name":"Biochemical Analysis and Sensing Techniques","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11584","display_name":"Biochemical Analysis and Sensing Techniques","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.007899999618530273,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-sweeteners","display_name":"artificial sweeteners","score":0.9990000128746033},{"id":"https://openalex.org/keywords/aspartame","display_name":"aspartame","score":0.8539999723434448},{"id":"https://openalex.org/keywords/sucralose","display_name":"sucralose","score":1.0},{"id":"https://openalex.org/keywords/weight-gain","display_name":"weight gain","score":0.8270000219345093},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9419999718666077},{"id":"https://openalex.org/keywords/sugar-cravings","display_name":"sugar cravings","score":0.8640000224113464},{"id":"https://openalex.org/keywords/food-reward","display_name":"food reward","score":0.953000009059906},{"id":"https://openalex.org/keywords/neurobiology-of-eating","display_name":"neurobiology of eating","score":0.8569999933242798},{"id":"https://openalex.org/keywords/dieting","display_name":"dieting","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C2776480571","wikidata":"https://www.wikidata.org/wiki/Q410209","display_name":"Sucralose","level":2,"score":0.8691439628601074},{"id":"https://openalex.org/C2911055575","wikidata":"https://www.wikidata.org/wiki/Q626292","display_name":"Artificial Sweetener","level":3,"score":0.6947807669639587},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5715970396995544},{"id":"https://openalex.org/C2778278337","wikidata":"https://www.wikidata.org/wiki/Q182040","display_name":"Aspartame","level":2,"score":0.48740723729133606},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.47296351194381714},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.45755115151405334},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.34937775135040283},{"id":"https://openalex.org/C2777108408","wikidata":"https://www.wikidata.org/wiki/Q11002","display_name":"Sugar","level":2,"score":0.295451819896698},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.2829413414001465},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20522606372833252},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009042","descriptor_name":"Motivation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D013395","descriptor_name":"Sucrose","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013549","descriptor_name":"Sweetening Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015430","descriptor_name":"Weight Gain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2892765","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2892765","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yale J Biol Med","raw_type":"Text"},{"id":"pmid:20589192","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20589192","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Yale journal of biology and medicine","raw_type":"Journal Article"},{"id":"mag:189019077","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20589192","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null},{"id":"mag:2465770572","doi":null,"is_oa":false,"landing_page_url":"http://www.feingold.org/Research/PDFstudies/Yang2010.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2892765","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2892765","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yale J Biol Med","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8560000061988831}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W99753603","https://openalex.org/W370404822","https://openalex.org/W1505241555","https://openalex.org/W1563351967","https://openalex.org/W1755490693","https://openalex.org/W1766326657","https://openalex.org/W1779095361","https://openalex.org/W1845795978","https://openalex.org/W1858394644","https://openalex.org/W1963981973","https://openalex.org/W1968201405","https://openalex.org/W1968823391","https://openalex.org/W1972102676","https://openalex.org/W1976052993","https://openalex.org/W1979700749","https://openalex.org/W1989944606","https://openalex.org/W1994785080","https://openalex.org/W1998773029","https://openalex.org/W2009709597","https://openalex.org/W2018846228","https://openalex.org/W2022478707","https://openalex.org/W2027234177","https://openalex.org/W2033233990","https://openalex.org/W2033941910","https://openalex.org/W2035066415","https://openalex.org/W2040106495","https://openalex.org/W2046460103","https://openalex.org/W2052366277","https://openalex.org/W2052959144","https://openalex.org/W2060432728","https://openalex.org/W2064071949","https://openalex.org/W2066725447","https://openalex.org/W2067059133","https://openalex.org/W2076601678","https://openalex.org/W2096546427","https://openalex.org/W2101301224","https://openalex.org/W2104546835","https://openalex.org/W2106411247","https://openalex.org/W2125063102","https://openalex.org/W2125745062","https://openalex.org/W2130481665","https://openalex.org/W2132779121","https://openalex.org/W2136550122","https://openalex.org/W2140703033","https://openalex.org/W2147496400","https://openalex.org/W2150599493","https://openalex.org/W2150685626","https://openalex.org/W2153546290","https://openalex.org/W2158287537","https://openalex.org/W2159187409","https://openalex.org/W2164839792","https://openalex.org/W2325749936","https://openalex.org/W2409563441","https://openalex.org/W2421218987"],"related_works":["https://openalex.org/W2465770572","https://openalex.org/W2806371225","https://openalex.org/W2797981032","https://openalex.org/W2338098990","https://openalex.org/W7126354334","https://openalex.org/W2794062868","https://openalex.org/W3084331852","https://openalex.org/W7160363341","https://openalex.org/W2030366150","https://openalex.org/W2908276145"],"abstract_inverted_index":{"America's":[0],"obesity":[1],"epidemic":[2],"has":[3],"gathered":[4],"much":[5],"media":[6],"attention":[7],"recently.":[8],"A":[9],"rise":[10],"in":[11,24,43,94,104,128],"the":[12,15,25,99,111,131],"percent":[13],"of":[14,28,101,130,133],"population":[16],"who":[17],"are":[18],"obese":[19],"coincides":[20],"with":[21,85],"an":[22],"increase":[23],"widespread":[26],"use":[27],"non-caloric":[29],"artificial":[30,71,102],"sweeteners,":[31],"such":[32],"as":[33],"aspartame":[34],"(e.g.,":[35,40],"Diet":[36],"Coke)":[37],"and":[38,50,113],"sucralose":[39],"Pepsi":[41],"One),":[42],"food":[44,134],"products":[45,63],"(Figure":[46],"1).":[47],"Both":[48],"forward":[49],"reverse":[51],"causalities":[52],"have":[53],"been":[54],"proposed.":[55],"While":[56],"people":[57],"often":[58],"choose":[59],"\"diet\"":[60],"or":[61],"\"light\"":[62],"to":[64,75,124],"lose":[65],"weight,":[66],"research":[67],"studies":[68],"suggest":[69],"that":[70],"sweeteners":[72,103],"may":[73],"contribute":[74],"weight":[76],"gain.":[77],"In":[78],"this":[79],"mini-review,":[80],"inspired":[81],"by":[82],"a":[83,105],"discussion":[84],"Dr.":[86],"Dana":[87],"Small":[88],"at":[89],"Yale's":[90],"Neuroscience":[91],"2010":[92],"conference":[93],"April,":[95],"I":[96,108,122],"first":[97],"examine":[98],"development":[100],"historic":[106],"context.":[107],"then":[109],"summarize":[110],"epidemiological":[112],"experimental":[114],"evidence":[115],"concerning":[116],"their":[117],"effects":[118,127],"on":[119],"weight.":[120],"Finally,":[121],"attempt":[123],"explain":[125],"those":[126],"light":[129],"neurobiology":[132],"reward.":[135]},"counts_by_year":[{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":24},{"year":2019,"cited_by_count":22},{"year":2018,"cited_by_count":34},{"year":2017,"cited_by_count":27},{"year":2016,"cited_by_count":26},{"year":2015,"cited_by_count":22},{"year":2014,"cited_by_count":17},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":13}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}