{"id":"https://openalex.org/W1883453076","doi":"https://doi.org/10.1099/0022-1317-81-2-407","title":"Diminished secondary CTL response in draining lymph nodes on cutaneous challenge with herpes simplex virus","display_name":"Diminished secondary CTL response in draining lymph nodes on cutaneous challenge with herpes simplex virus","publication_year":2000,"publication_date":"2000-02-01","ids":{"openalex":"https://openalex.org/W1883453076","doi":"https://doi.org/10.1099/0022-1317-81-2-407","mag":"1883453076","pmid":"https://pubmed.ncbi.nlm.nih.gov/10644839"},"language":"en","primary_location":{"id":"doi:10.1099/0022-1317-81-2-407","doi":"https://doi.org/10.1099/0022-1317-81-2-407","is_oa":false,"landing_page_url":"https://doi.org/10.1099/0022-1317-81-2-407","pdf_url":null,"source":{"id":"https://openalex.org/S103035011","display_name":"Journal of General Virology","issn_l":"0022-1317","issn":["0022-1317","1465-2099"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320497","host_organization_name":"Microbiology Society","host_organization_lineage":["https://openalex.org/P4310320497"],"host_organization_lineage_names":["Microbiology Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of General Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018173229","display_name":"Claerwen M. Jones","orcid":"https://orcid.org/0000-0001-8594-9554","observed_orcids":["https://orcid.org/0000-0001-8594-9554"]},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Claerwen Jones","raw_affiliation_strings":["Department of Pathology and Immunology, Monash Medical School, Commercial Road, Prahran, Victoria 3181, Australia","Department of Pathology and Immunology, Monash Medical School, Commercial Road, Prahran, Victoria 3181, Australia1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Immunology, Monash Medical School, Commercial Road, Prahran, Victoria 3181, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Department of Pathology and Immunology, Monash Medical School, Commercial Road, Prahran, Victoria 3181, Australia1","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059544767","display_name":"Stephen Cose","orcid":"https://orcid.org/0000-0002-5156-037X","observed_orcids":["https://orcid.org/0000-0002-5156-037X"]},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Stephen Cose","raw_affiliation_strings":["Department of Pathology and Immunology, Monash Medical School, Commercial Road, Prahran, Victoria 3181, Australia","Department of Pathology and Immunology, Monash Medical School, Commercial Road, Prahran, Victoria 3181, Australia1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Immunology, Monash Medical School, Commercial Road, Prahran, Victoria 3181, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Department of Pathology and Immunology, Monash Medical School, Commercial Road, Prahran, Victoria 3181, Australia1","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044225458","display_name":"James M. McNally","orcid":"https://orcid.org/0000-0002-6043-8560","observed_orcids":["https://orcid.org/0000-0002-6043-8560"]},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]},{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James McNally","raw_affiliation_strings":["Department of Microbiology and Immunology, Louisiana State University Medical Center, School of Medicine in Shreveport, Shreveport, LA 71130, USA","Department of Microbiology and Immunology, Louisiana State University Medical Center, School of Medicine in Shreveport, Shreveport, LA 71130, USA2"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Louisiana State University Medical Center, School of Medicine in Shreveport, Shreveport, LA 71130, USA","institution_ids":["https://openalex.org/I121820613","https://openalex.org/I81020160"]},{"raw_affiliation_string":"Department of Microbiology and Immunology, Louisiana State University Medical Center, School of Medicine in Shreveport, Shreveport, LA 71130, USA2","institution_ids":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037574752","display_name":"William R. Heath","orcid":"https://orcid.org/0000-0001-9670-259X","observed_orcids":["https://orcid.org/0000-0001-9670-259X"]},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]},{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"funder","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I196021976","display_name":"Walter and Eliza Hall Institute of Medical Research","ror":"https://ror.org/01b6kha49","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I196021976"]},{"id":"https://openalex.org/I81020160","display_name":"Louisiana State University Health Sciences Center Shreveport","ror":"https://ror.org/03151rh82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"William Heath","raw_affiliation_strings":["Immunology Division, The Walter and Eliza Hall Institute of Medical Research, P.O. Royal Melbourne Hospital, Parkville, Victoria 3050, Australia","Department of Microbiology and Immunology, Louisiana State University Medical Center, School of Medicine in Shreveport, Shreveport, LA 71130, USA2"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology Division, The Walter and Eliza Hall Institute of Medical Research, P.O. Royal Melbourne Hospital, Parkville, Victoria 3050, Australia","institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I196021976"]},{"raw_affiliation_string":"Department of Microbiology and Immunology, Louisiana State University Medical Center, School of Medicine in Shreveport, Shreveport, LA 71130, USA2","institution_ids":["https://openalex.org/I121820613","https://openalex.org/I81020160"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004453226","display_name":"Francis R. Carbone","orcid":"https://orcid.org/0000-0001-7233-9466","observed_orcids":["https://orcid.org/0000-0001-7233-9466"]},"institutions":[{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"funder","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I196021976","display_name":"Walter and Eliza Hall Institute of Medical Research","ror":"https://ror.org/01b6kha49","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I196021976"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Francis Carbone","raw_affiliation_strings":["Department of Pathology and Immunology, Monash Medical School, Commercial Road, Prahran, Victoria 3181, Australia","Immunology Division, The Walter and Eliza Hall Institute of Medical Research, P.O. Royal Melbourne Hospital, Parkville, Victoria 3050, Australia3"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Immunology, Monash Medical School, Commercial Road, Prahran, Victoria 3181, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Immunology Division, The Walter and Eliza Hall Institute of Medical Research, P.O. Royal Melbourne Hospital, Parkville, Victoria 3050, Australia3","institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I196021976"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5352,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.67125378,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"81","issue":"2","first_page":"407","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.032499998807907104,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-1","display_name":"herpes simplex virus type 1","score":0.9800000190734863},{"id":"https://openalex.org/keywords/glycoprotein-b","display_name":"glycoprotein B","score":0.8830000162124634},{"id":"https://openalex.org/keywords/cytotoxic-cd8-t-cells","display_name":"CD8+ cytotoxic T lymphocytes","score":0.921999990940094},{"id":"https://openalex.org/keywords/draining-lymph-nodes","display_name":"draining lymph nodes","score":0.7929999828338623},{"id":"https://openalex.org/keywords/recall-response","display_name":"recall response","score":0.8600000143051147},{"id":"https://openalex.org/keywords/memory-t-cells","display_name":"memory T cells","score":0.7990000247955322},{"id":"https://openalex.org/keywords/t-cell-activation","display_name":"T cell activation","score":0.4440000057220459},{"id":"https://openalex.org/keywords/skin-infections","display_name":"skin infections","score":0.5839999914169312},{"id":"https://openalex.org/keywords/popliteal-lymph-nodes","display_name":"popliteal lymph nodes","score":0.7480000257492065},{"id":"https://openalex.org/keywords/c57bl-6-mice","display_name":"C57BL/6 mice","score":0.8429999947547913}],"concepts":[{"id":"https://openalex.org/C147969180","wikidata":"https://www.wikidata.org/wiki/Q5014579","display_name":"CTL*","level":4,"score":0.9464218020439148},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.7408518195152283},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.7195227742195129},{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.6941735148429871},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.6205958127975464},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.5962887406349182},{"id":"https://openalex.org/C73588182","wikidata":"https://www.wikidata.org/wiki/Q2663023","display_name":"Cytolysis","level":4,"score":0.5950355529785156},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5841017961502075},{"id":"https://openalex.org/C2780190958","wikidata":"https://www.wikidata.org/wiki/Q1878776","display_name":"Lymphocytic choriomeningitis","level":4,"score":0.5611643195152283},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5520758628845215},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5472577810287476},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4922000467777252},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.260399729013443},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21351423859596252},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1810043454170227},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.09396448731422424},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0657554566860199}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002522","descriptor_name":"Chlorocebus aethiops","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003602","descriptor_name":"Cytotoxicity, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006561","descriptor_name":"Herpes Simplex","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006561","descriptor_name":"Herpes Simplex","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D007156","descriptor_name":"Immunologic Memory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014709","descriptor_name":"Vero Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014759","descriptor_name":"Viral Envelope Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016056","descriptor_name":"Immunodominant Epitopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016693","descriptor_name":"Receptors, Antigen, T-Cell, alpha-beta","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018259","descriptor_name":"Herpesvirus 1, Human","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1099/0022-1317-81-2-407","doi":"https://doi.org/10.1099/0022-1317-81-2-407","is_oa":false,"landing_page_url":"https://doi.org/10.1099/0022-1317-81-2-407","pdf_url":null,"source":{"id":"https://openalex.org/S103035011","display_name":"Journal of General Virology","issn_l":"0022-1317","issn":["0022-1317","1465-2099"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320497","host_organization_name":"Microbiology Society","host_organization_lineage":["https://openalex.org/P4310320497"],"host_organization_lineage_names":["Microbiology Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of General Virology","raw_type":"journal-article"},{"id":"pmid:10644839","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10644839","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of general virology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W1485596855","https://openalex.org/W1509666796","https://openalex.org/W1527802692","https://openalex.org/W1538250327","https://openalex.org/W1559097928","https://openalex.org/W1560041852","https://openalex.org/W1564049621","https://openalex.org/W1568059997","https://openalex.org/W1569140775","https://openalex.org/W1599781349","https://openalex.org/W1642090213","https://openalex.org/W1643711876","https://openalex.org/W1762612902","https://openalex.org/W1785570868","https://openalex.org/W1867467496","https://openalex.org/W1920792271","https://openalex.org/W1963578378","https://openalex.org/W1967891206","https://openalex.org/W1974906492","https://openalex.org/W1984915215","https://openalex.org/W2006645462","https://openalex.org/W2010436799","https://openalex.org/W2013800646","https://openalex.org/W2014730581","https://openalex.org/W2015778512","https://openalex.org/W2016495145","https://openalex.org/W2035722496","https://openalex.org/W2040053821","https://openalex.org/W2041218370","https://openalex.org/W2042626190","https://openalex.org/W2048157537","https://openalex.org/W2049952729","https://openalex.org/W2063916242","https://openalex.org/W2067069532","https://openalex.org/W2069340283","https://openalex.org/W2079946290","https://openalex.org/W2081266951","https://openalex.org/W2084146385","https://openalex.org/W2112923458","https://openalex.org/W2115136218","https://openalex.org/W2117230571","https://openalex.org/W2125650988","https://openalex.org/W2125901635","https://openalex.org/W2132168007","https://openalex.org/W2138773604","https://openalex.org/W2139850147","https://openalex.org/W2140202337","https://openalex.org/W2160985360","https://openalex.org/W2171986697","https://openalex.org/W2410709630","https://openalex.org/W2992138720","https://openalex.org/W4376545216"],"related_works":["https://openalex.org/W1762612902","https://openalex.org/W2123448680","https://openalex.org/W2118472352","https://openalex.org/W2115136218","https://openalex.org/W1521443135","https://openalex.org/W2100024567","https://openalex.org/W2169163738","https://openalex.org/W2105895969","https://openalex.org/W7098902033","https://openalex.org/W1509666796"],"abstract_inverted_index":{"We":[0,77],"have":[1,58],"shown":[2],"that":[3,79,137],"C57BL/6-derived":[4],"CD8(+)":[5],"CTL":[6,44,64,72,110,174,232],"specific":[7],"for":[8],"an":[9],"immunodominant":[10],"herpes":[11],"simplex":[12],"virus":[13,130],"type":[14],"1":[15],"(HSV-1)":[16],"glycoprotein":[17],"B":[18],"(gB)":[19],"determinant":[20],"express":[21],"a":[22,149,182,230],"highly":[23],"conserved":[24],"Vbeta10/junctional":[25],"sequence":[26],"combination.":[27],"This":[28,143],"extreme":[29],"T":[30,114,154,191,223],"cell":[31,115,155],"receptor":[32],"beta-chain":[33],"bias":[34],"can":[35],"be":[36],"used":[37],"to":[38,74],"track":[39],"the":[40,49,60,66,97,106,112,140,159,169,194,200,206,235],"activation":[41,219],"of":[42,51,62,108,152,172,185,188,202,217,220,237],"gB-specific":[43,63,80,145,173],"in":[45,65,111,139,176,204,215,226],"lymph":[46,86,161,196],"nodes":[47,87,162,197],"draining":[48,88,160,238],"site":[50],"HSV-1":[52,75],"infection.":[53,76],"In":[54],"this":[55,103,164,177],"report":[56],"we":[57],"examined":[59],"accumulation":[61,107,175,187],"primary":[67,98,141,207],"and":[68,124,208],"secondary":[69,127,209,231],"or":[70],"recall":[71,165],"responses":[73],"found":[78,101,157],"cytolytic":[81,146],"activity":[82,147],"present":[83],"within":[84,158,193],"popliteal":[85,195],"HSV-infected":[89],"foot-pads":[90],"peaked":[91,120],"at":[92,234],"day":[93],"5":[94],"post-infection":[95],"during":[96,163,229],"response.":[99,142],"As":[100],"previously,":[102],"correlates":[104],"with":[105,129,168],"Vbeta10(+)CD8(+)":[109,153,189],"activated":[113,190],"subset.":[116],"Lymph":[117],"node-derived":[118],"cytotoxicity":[119],"between":[121],"days":[122],"3":[123],"4":[125],"on":[126],"challenge":[128],"and,":[131],"somewhat":[132],"surprisingly,":[133],"was":[134,181],"considerably":[135],"below":[136],"seen":[138],"reduced":[144],"mirrored":[148],"near":[150],"absence":[151],"enrichment":[156],"response,":[166],"consistent":[167],"overall":[170],"diminution":[171],"site.":[178],"Finally,":[179],"there":[180],"second":[183],"wave":[184],"biased":[186],"cells":[192,224],"well":[198],"after":[199],"resolution":[201],"infection":[203],"both":[205],"responses.":[210],"These":[211],"results":[212],"are":[213],"discussed":[214],"terms":[216],"preferential":[218],"virus-specific":[221],"memory":[222],"directly":[225],"infected":[227],"tissues":[228],"response":[233],"expense":[236],"lymphoid":[239],"organs.":[240]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}