{"id":"https://openalex.org/W1879709643","doi":"https://doi.org/10.1111/j.1346-8138.2010.00931.x","title":"Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome with review of the relevant published work","display_name":"Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome with review of the relevant published work","publication_year":2010,"publication_date":"2010-11-11","ids":{"openalex":"https://openalex.org/W1879709643","doi":"https://doi.org/10.1111/j.1346-8138.2010.00931.x","mag":"1879709643","pmid":"https://pubmed.ncbi.nlm.nih.gov/21269311"},"language":"en","primary_location":{"id":"doi:10.1111/j.1346-8138.2010.00931.x","doi":"https://doi.org/10.1111/j.1346-8138.2010.00931.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1346-8138.2010.00931.x","pdf_url":null,"source":{"id":"https://openalex.org/S143887118","display_name":"The Journal of Dermatology","issn_l":"0385-2407","issn":["0385-2407","1346-8138"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Dermatology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1879709643"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101762700","display_name":"Zigang Zhao","orcid":"https://orcid.org/0000-0003-3004-1578","observed_orcids":["https://orcid.org/0000-0003-3004-1578"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zigang ZHAO","raw_affiliation_strings":["Department of Dermatology, PLA General Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, PLA General Hospital, Beijing, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100414049","display_name":"Ying Li","orcid":"https://orcid.org/0000-0001-7554-0958","observed_orcids":["https://orcid.org/0000-0001-7554-0958"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying LI","raw_affiliation_strings":["Departments of Dermatology","Radiology, the PLA General Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Dermatology","institution_ids":[]},{"raw_affiliation_string":"Radiology, the PLA General Hospital, Beijing, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100384461","display_name":"Yuanyuan Li","orcid":"https://orcid.org/0000-0003-4967-3890","observed_orcids":["https://orcid.org/0000-0003-4967-3890"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuanyuan LI","raw_affiliation_strings":["Departments of Dermatology","Radiology, the PLA General Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Dermatology","institution_ids":[]},{"raw_affiliation_string":"Radiology, the PLA General Hospital, Beijing, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103265405","display_name":"Hua Zhao","orcid":"https://orcid.org/0000-0002-8726-9058","observed_orcids":["https://orcid.org/0000-0002-8726-9058"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Hua ZHAO","raw_affiliation_strings":["Departments of Dermatology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Dermatology","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051742681","display_name":"Hengjin Li","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hengjin LI","raw_affiliation_strings":["Departments of Dermatology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Dermatology","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5103265405"],"corresponding_institution_ids":[],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":null,"fwci":2.4018,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.87451851,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"38","issue":"2","first_page":"155","last_page":"159"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13328","display_name":"Osteomyelitis and Bone Disorders Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13328","display_name":"Osteomyelitis and Bone Disorders Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12328","display_name":"Autoimmune and Inflammatory Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14057","display_name":"Hypertrophic osteoarthropathy and related conditions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sapho-syndrome","display_name":"SAPHO syndrome","score":1.0},{"id":"https://openalex.org/keywords/synovitis","display_name":"synovitis","score":0.9380000233650208},{"id":"https://openalex.org/keywords/acne-vulgaris","display_name":"acne","score":0.8420000076293945},{"id":"https://openalex.org/keywords/pustulosis","display_name":"pustulosis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/hyperostosis","display_name":"hyperostosis","score":0.9789999723434448},{"id":"https://openalex.org/keywords/osteitis","display_name":"osteitis","score":0.9929999709129333},{"id":"https://openalex.org/keywords/osteoarthropathy","display_name":"osteoarthropathy","score":0.9710000157356262},{"id":"https://openalex.org/keywords/anterior-chest-wall","display_name":"anterior chest wall","score":0.8539999723434448},{"id":"https://openalex.org/keywords/early-diagnosis","display_name":"early diagnosis","score":0.7149999737739563},{"id":"https://openalex.org/keywords/antibiotic-therapy","display_name":"antibiotic therapy","score":0.8339999914169312}],"concepts":[{"id":"https://openalex.org/C2776674182","wikidata":"https://www.wikidata.org/wiki/Q1515163","display_name":"SAPHO syndrome","level":5,"score":0.9866272211074829},{"id":"https://openalex.org/C2779234776","wikidata":"https://www.wikidata.org/wiki/Q7262033","display_name":"Pustulosis","level":4,"score":0.9569891095161438},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8945812582969666},{"id":"https://openalex.org/C2909516574","wikidata":"https://www.wikidata.org/wiki/Q2562329","display_name":"Palmoplantar pustulosis","level":3,"score":0.8871904611587524},{"id":"https://openalex.org/C2779782008","wikidata":"https://www.wikidata.org/wiki/Q1632552","display_name":"Hyperostosis","level":2,"score":0.8818730115890503},{"id":"https://openalex.org/C2781343496","wikidata":"https://www.wikidata.org/wiki/Q1178507","display_name":"Osteitis","level":3,"score":0.8661208152770996},{"id":"https://openalex.org/C2779244835","wikidata":"https://www.wikidata.org/wiki/Q538432","display_name":"Synovitis","level":3,"score":0.782345175743103},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.7496225833892822},{"id":"https://openalex.org/C2777673923","wikidata":"https://www.wikidata.org/wiki/Q79928","display_name":"Acne","level":2,"score":0.7367408871650696},{"id":"https://openalex.org/C2776387214","wikidata":"https://www.wikidata.org/wiki/Q2787011","display_name":"Chronic recurrent multifocal osteomyelitis","level":4,"score":0.45974403619766235},{"id":"https://openalex.org/C2780551157","wikidata":"https://www.wikidata.org/wiki/Q938983","display_name":"Osteomyelitis","level":2,"score":0.4393855631351471},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.24610310792922974},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.18411049246788025},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09174129366874695},{"id":"https://openalex.org/C2780564577","wikidata":"https://www.wikidata.org/wiki/Q179945","display_name":"Psoriasis","level":2,"score":0.07168266177177429}],"mesh":[{"descriptor_ui":"D000077339","descriptor_name":"Leflunomide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003879","descriptor_name":"Dermatologic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006229","descriptor_name":"Hand Dermatoses","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006229","descriptor_name":"Hand Dermatoses","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007555","descriptor_name":"Isoxazoles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007868","descriptor_name":"Leg Dermatoses","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D007868","descriptor_name":"Leg Dermatoses","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008727","descriptor_name":"Methotrexate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020083","descriptor_name":"Acquired Hyperostosis Syndrome","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D020083","descriptor_name":"Acquired Hyperostosis Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1346-8138.2010.00931.x","doi":"https://doi.org/10.1111/j.1346-8138.2010.00931.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1346-8138.2010.00931.x","pdf_url":null,"source":{"id":"https://openalex.org/S143887118","display_name":"The Journal of Dermatology","issn_l":"0385-2407","issn":["0385-2407","1346-8138"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Dermatology","raw_type":"journal-article"},{"id":"pmid:21269311","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21269311","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of dermatology","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1682906924","https://openalex.org/W2012623404","https://openalex.org/W2013489656","https://openalex.org/W2014343179","https://openalex.org/W2014961321","https://openalex.org/W2047978035","https://openalex.org/W2054218135","https://openalex.org/W2131952834","https://openalex.org/W2132989904","https://openalex.org/W2157705460","https://openalex.org/W2159598113","https://openalex.org/W2412575171"],"related_works":["https://openalex.org/W2412575171","https://openalex.org/W2415461705","https://openalex.org/W1999517175","https://openalex.org/W3044659102","https://openalex.org/W1556291589","https://openalex.org/W3204873637","https://openalex.org/W3082246015","https://openalex.org/W2925126481","https://openalex.org/W3025852423","https://openalex.org/W2002950632"],"abstract_inverted_index":{"Synovitis,":[0],"acne,":[1],"pustulosis,":[2],"hyperostosis":[3],"and":[4,14,40],"osteitis":[5],"(SAPHO)":[6],"syndrome":[7,51],"is":[8,33],"characterized":[9],"by":[10],"various":[11],"dermatological":[12],"manifestations":[13],"osteoarthropathy":[15],"frequently":[16],"localized":[17],"to":[18,35],"the":[19,55],"anterior":[20],"chest":[21],"wall.":[22],"Dermatologists":[23],"should":[24],"be":[25],"familiar":[26],"with":[27,52],"this":[28,50],"syndrome.":[29],"Its":[30],"early":[31],"diagnosis":[32],"important":[34],"avoid":[36],"prolonged":[37],"antibiotic":[38],"treatments":[39],"unnecessary":[41],"invasive":[42],"procedures.":[43],"We":[44],"report":[45],"a":[46],"new":[47],"case":[48],"of":[49,54],"review":[53],"relevant":[56],"published":[57],"work.":[58]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}