{"id":"https://openalex.org/W187547537","doi":"https://doi.org/10.1007/978-3-642-50036-7_7","title":"Pharmacokinetic Models and Positron Emission Tomography: Studies of Physiologic and Pathophysiologic Conditions","display_name":"Pharmacokinetic Models and Positron Emission Tomography: Studies of Physiologic and Pathophysiologic Conditions","publication_year":1983,"publication_date":"1983-01-01","ids":{"openalex":"https://openalex.org/W187547537","doi":"https://doi.org/10.1007/978-3-642-50036-7_7","mag":"187547537"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-50036-7_7","doi":"https://doi.org/10.1007/978-3-642-50036-7_7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-50036-7_7","pdf_url":null,"source":{"id":"https://openalex.org/S4210168038","display_name":"Lecture notes in biomathematics","issn_l":"0341-633X","issn":["0341-633X","2196-9981"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Biomathematics","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2491491422","display_name":"Tracer Kinetics and Physiologic Modeling"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110236686","display_name":"Martin Reivich","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin Reivich","raw_affiliation_strings":["University of Pennsylvania, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088003622","display_name":"Abass A. Alavi","orcid":"https://orcid.org/0000-0002-2442-7901","observed_orcids":["https://orcid.org/0000-0002-2442-7901"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abass Alavi","raw_affiliation_strings":["University of Pennsylvania, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I79576946"],"apc_list":null,"apc_paid":null,"fwci":0.7558,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.73630137,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"345","last_page":"383"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.00800000037997961,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pharmacokinetic-modeling","display_name":"pharmacokinetic modeling","score":0.9629999995231628},{"id":"https://openalex.org/keywords/positron-emission-tomography","display_name":"positron emission tomography","score":0.9879999756813049},{"id":"https://openalex.org/keywords/regional-cerebral-blood-flow","display_name":"regional cerebral blood flow","score":0.8349999785423279},{"id":"https://openalex.org/keywords/cerebral-glucose-metabolism","display_name":"brain glucose metabolism","score":0.7260000109672546},{"id":"https://openalex.org/keywords/18f-fluorodeoxyglucose","display_name":"18F-fluorodeoxyglucose","score":0.9700000286102295},{"id":"https://openalex.org/keywords/hemispheric-asymmetry","display_name":"hemispheric lateralization","score":0.7200000286102295}],"concepts":[{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.8061807155609131},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.7968630194664001},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.6948422193527222},{"id":"https://openalex.org/C3018390542","wikidata":"https://www.wikidata.org/wiki/Q1073","display_name":"Brain function","level":2,"score":0.5233035087585449},{"id":"https://openalex.org/C2777415128","wikidata":"https://www.wikidata.org/wiki/Q419849","display_name":"Fluorodeoxyglucose","level":3,"score":0.5181423425674438},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.5169943571090698},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4748820662498474},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.4292212128639221},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.42398199439048767},{"id":"https://openalex.org/C202100949","wikidata":"https://www.wikidata.org/wiki/Q3229","display_name":"Positron","level":3,"score":0.4236159026622772},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39078912138938904},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.36736515164375305},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.27677279710769653},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.26469436287879944},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.17820242047309875},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07151895761489868},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C147120987","wikidata":"https://www.wikidata.org/wiki/Q2225","display_name":"Electron","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-642-50036-7_7","doi":"https://doi.org/10.1007/978-3-642-50036-7_7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-50036-7_7","pdf_url":null,"source":{"id":"https://openalex.org/S4210168038","display_name":"Lecture notes in biomathematics","issn_l":"0341-633X","issn":["0341-633X","2196-9981"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Biomathematics","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":171,"referenced_works":["https://openalex.org/W23097016","https://openalex.org/W83812766","https://openalex.org/W125570795","https://openalex.org/W170156558","https://openalex.org/W224993226","https://openalex.org/W569868034","https://openalex.org/W579244164","https://openalex.org/W589263364","https://openalex.org/W646969770","https://openalex.org/W647620331","https://openalex.org/W1210424432","https://openalex.org/W1212045103","https://openalex.org/W1525261957","https://openalex.org/W1587156225","https://openalex.org/W1614353075","https://openalex.org/W1681903657","https://openalex.org/W1875624699","https://openalex.org/W1964966413","https://openalex.org/W1967008186","https://openalex.org/W1968054082","https://openalex.org/W1968678910","https://openalex.org/W1969054327","https://openalex.org/W1969221733","https://openalex.org/W1969834435","https://openalex.org/W1970803763","https://openalex.org/W1972335150","https://openalex.org/W1972925419","https://openalex.org/W1973422620","https://openalex.org/W1976511025","https://openalex.org/W1976715146","https://openalex.org/W1978264368","https://openalex.org/W1978633932","https://openalex.org/W1978643925","https://openalex.org/W1978851091","https://openalex.org/W1982465545","https://openalex.org/W1987554583","https://openalex.org/W1987939219","https://openalex.org/W1990945773","https://openalex.org/W1992914341","https://openalex.org/W1994625228","https://openalex.org/W1995725269","https://openalex.org/W1996454733","https://openalex.org/W1996639080","https://openalex.org/W1997919191","https://openalex.org/W1998699743","https://openalex.org/W1999781780","https://openalex.org/W2004986025","https://openalex.org/W2005550961","https://openalex.org/W2007856779","https://openalex.org/W2007935128","https://openalex.org/W2008621328","https://openalex.org/W2010120109","https://openalex.org/W2011269223","https://openalex.org/W2012746413","https://openalex.org/W2012849393","https://openalex.org/W2013885616","https://openalex.org/W2015091323","https://openalex.org/W2015382915","https://openalex.org/W2018439295","https://openalex.org/W2020079102","https://openalex.org/W2020934004","https://openalex.org/W2021141393","https://openalex.org/W2021377024","https://openalex.org/W2022228074","https://openalex.org/W2022424636","https://openalex.org/W2022772618","https://openalex.org/W2022843424","https://openalex.org/W2023119770","https://openalex.org/W2024913110","https://openalex.org/W2026534529","https://openalex.org/W2027217568","https://openalex.org/W2028671462","https://openalex.org/W2028795001","https://openalex.org/W2028824290","https://openalex.org/W2030683917","https://openalex.org/W2034103378","https://openalex.org/W2034298442","https://openalex.org/W2037959172","https://openalex.org/W2043889745","https://openalex.org/W2046723869","https://openalex.org/W2050112450","https://openalex.org/W2051914288","https://openalex.org/W2051955410","https://openalex.org/W2052163178","https://openalex.org/W2052318178","https://openalex.org/W2052703739","https://openalex.org/W2054716745","https://openalex.org/W2056919475","https://openalex.org/W2057058516","https://openalex.org/W2059382850","https://openalex.org/W2061523281","https://openalex.org/W2062402128","https://openalex.org/W2063139320","https://openalex.org/W2065519093","https://openalex.org/W2068147451","https://openalex.org/W2068543581","https://openalex.org/W2068665108","https://openalex.org/W2070820559","https://openalex.org/W2073441246","https://openalex.org/W2075714485","https://openalex.org/W2076220552","https://openalex.org/W2077370148","https://openalex.org/W2081293666","https://openalex.org/W2084158465","https://openalex.org/W2084506343","https://openalex.org/W2084842110","https://openalex.org/W2084852011","https://openalex.org/W2087173000","https://openalex.org/W2090203522","https://openalex.org/W2090306035","https://openalex.org/W2090755970","https://openalex.org/W2090774324","https://openalex.org/W2095093571","https://openalex.org/W2097912113","https://openalex.org/W2100446760","https://openalex.org/W2104155521","https://openalex.org/W2105118669","https://openalex.org/W2106279260","https://openalex.org/W2108943156","https://openalex.org/W2126657498","https://openalex.org/W2136210314","https://openalex.org/W2139220163","https://openalex.org/W2139725823","https://openalex.org/W2141395957","https://openalex.org/W2141797002","https://openalex.org/W2146939272","https://openalex.org/W2147293981","https://openalex.org/W2153961094","https://openalex.org/W2158815034","https://openalex.org/W2159615205","https://openalex.org/W2161146662","https://openalex.org/W2164111076","https://openalex.org/W2167534910","https://openalex.org/W2168542458","https://openalex.org/W2170591739","https://openalex.org/W2177960617","https://openalex.org/W2243456881","https://openalex.org/W2253776861","https://openalex.org/W2256061676","https://openalex.org/W2277047617","https://openalex.org/W2295353816","https://openalex.org/W2315317701","https://openalex.org/W2315693760","https://openalex.org/W2318595692","https://openalex.org/W2324134059","https://openalex.org/W2327681121","https://openalex.org/W2327950567","https://openalex.org/W2330817629","https://openalex.org/W2335787466","https://openalex.org/W2396817529","https://openalex.org/W2407761715","https://openalex.org/W2410857416","https://openalex.org/W2418763445","https://openalex.org/W2418919605","https://openalex.org/W2431523525","https://openalex.org/W2464379742","https://openalex.org/W2468646816","https://openalex.org/W2491833585","https://openalex.org/W2625975446","https://openalex.org/W2740793970","https://openalex.org/W2753561812","https://openalex.org/W2771488840","https://openalex.org/W2780526305","https://openalex.org/W2889333363","https://openalex.org/W2980946502","https://openalex.org/W4205701318","https://openalex.org/W4239295342","https://openalex.org/W4252936338","https://openalex.org/W4253815668","https://openalex.org/W4285719527","https://openalex.org/W4298078826"],"related_works":["https://openalex.org/W1971967740","https://openalex.org/W3149083238","https://openalex.org/W1989780016","https://openalex.org/W204460627","https://openalex.org/W1957011301","https://openalex.org/W1494043695","https://openalex.org/W2502928391","https://openalex.org/W2338677407","https://openalex.org/W184208920","https://openalex.org/W2498930197"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}
