{"id":"https://openalex.org/W187359374","doi":"https://doi.org/10.1073/pnas.012540899","title":"The glycosynapse","display_name":"The glycosynapse","publication_year":2002,"publication_date":"2002-01-02","ids":{"openalex":"https://openalex.org/W187359374","doi":"https://doi.org/10.1073/pnas.012540899","mag":"187359374","pmid":"https://pubmed.ncbi.nlm.nih.gov/11773621","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/117543"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.012540899","doi":"https://doi.org/10.1073/pnas.012540899","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.012540899","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/117543","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070398233","display_name":"Sen\u2010itiroh Hakomori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sen-itiroh Hakomori","raw_affiliation_strings":["Pacific Northwest Research Institute, 720 Broadway, Seattle, WA 98122-4327, and Departments of Pathobiology and Microbiology, University of Washington, Seattle, WA 98195","Division of Biomembrane Research, Pacific Northwest Research Institute, 720 Broadway, Seattle, WA 98122-4327","Pacific Northwest Research Institute, 720 Broadway, Seattle, WA 98122-4327,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pacific Northwest Research Institute, 720 Broadway, Seattle, WA 98122-4327, and Departments of Pathobiology and Microbiology, University of Washington, Seattle, WA 98195","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Division of Biomembrane Research, Pacific Northwest Research Institute, 720 Broadway, Seattle, WA 98122-4327","institution_ids":[]},{"raw_affiliation_string":"Pacific Northwest Research Institute, 720 Broadway, Seattle, WA 98122-4327,","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5070398233"],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":null,"apc_paid":null,"fwci":2.8575,"has_fulltext":false,"cited_by_count":505,"citation_normalized_percentile":{"value":0.93363914,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"99","issue":"1","first_page":"225","last_page":"232"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.510699987411499,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.510699987411499,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.2361000031232834,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.21119999885559082,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipid-rafts","display_name":"lipid rafts","score":0.781000018119812},{"id":"https://openalex.org/keywords/glycosphingolipids","display_name":"glycosphingolipids","score":0.8930000066757202},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.8840000033378601},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"signal transduction","score":0.9980000257492065},{"id":"https://openalex.org/keywords/tetraspanins","display_name":"tetraspanins","score":0.9610000252723694},{"id":"https://openalex.org/keywords/mucin-type-glycoproteins","display_name":"mucin-type glycoproteins","score":0.8949999809265137},{"id":"https://openalex.org/keywords/o-glycosylation","display_name":"O-glycosylation","score":0.8960000276565552},{"id":"https://openalex.org/keywords/n-glycosylation","display_name":"N-glycosylation","score":0.8169999718666077},{"id":"https://openalex.org/keywords/gangliosides","display_name":"gangliosides","score":0.9599999785423279},{"id":"https://openalex.org/keywords/immunological-synapse","display_name":"immunological synapse","score":0.8500000238418579}],"concepts":[{"id":"https://openalex.org/C2777208748","wikidata":"https://www.wikidata.org/wiki/Q24773957","display_name":"Tetraspanin","level":3,"score":0.9320414066314697},{"id":"https://openalex.org/C134088382","wikidata":"https://www.wikidata.org/wiki/Q6556364","display_name":"Lipid microdomain","level":3,"score":0.6854062080383301},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6025214195251465},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.5688216686248779},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.5431526899337769},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5386867523193359},{"id":"https://openalex.org/C79266657","wikidata":"https://www.wikidata.org/wiki/Q424178","display_name":"Lipid raft","level":3,"score":0.5125398635864258},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.492617666721344},{"id":"https://openalex.org/C9756297","wikidata":"https://www.wikidata.org/wiki/Q126223","display_name":"Immunological synapse","level":5,"score":0.4666908383369446},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.41580620408058167},{"id":"https://openalex.org/C118892022","wikidata":"https://www.wikidata.org/wiki/Q7834587","display_name":"Transmembrane domain","level":3,"score":0.41543513536453247},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3708600103855133},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2236289381980896},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.21814975142478943},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.20049849152565002},{"id":"https://openalex.org/C19317047","wikidata":"https://www.wikidata.org/wiki/Q412037","display_name":"T-cell receptor","level":4,"score":0.17319971323013306},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.1288594901561737},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.10069015622138977},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005732","descriptor_name":"Gangliosides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006028","descriptor_name":"Glycosphingolipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006031","descriptor_name":"Glycosylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.012540899","doi":"https://doi.org/10.1073/pnas.012540899","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.012540899","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:117543","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/117543","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:11773621","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11773621","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"mag:2987732462","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/naid/80015142532","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Proc Natl Acad Sci USA","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:117543","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/117543","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1275593604","display_name":"SPHINGOSINE DEPENDENT KINASE AND CARCINOGENESIS","funder_award_id":"R01CA082167","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G401348875","display_name":"GLYCOLIPIDS--CELL INTERACTION/PROLIFERATION/ONCOGENESIS","funder_award_id":"R35CA042505","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5049934685","display_name":"Glycosynapses in cancer cell adhesion and signaling","funder_award_id":"R01CA080054","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":137,"referenced_works":["https://openalex.org/W24722359","https://openalex.org/W92485630","https://openalex.org/W565817114","https://openalex.org/W595883607","https://openalex.org/W606298846","https://openalex.org/W1222044264","https://openalex.org/W1480374655","https://openalex.org/W1482008147","https://openalex.org/W1488620239","https://openalex.org/W1511331055","https://openalex.org/W1515952044","https://openalex.org/W1522379684","https://openalex.org/W1525426202","https://openalex.org/W1527325255","https://openalex.org/W1531203186","https://openalex.org/W1532637157","https://openalex.org/W1537880401","https://openalex.org/W1544796307","https://openalex.org/W1546312651","https://openalex.org/W1549194476","https://openalex.org/W1549953248","https://openalex.org/W1550055978","https://openalex.org/W1551978087","https://openalex.org/W1564861448","https://openalex.org/W1565376547","https://openalex.org/W1569852946","https://openalex.org/W1574227588","https://openalex.org/W1575603949","https://openalex.org/W1582740601","https://openalex.org/W1585454125","https://openalex.org/W1588043332","https://openalex.org/W1602804242","https://openalex.org/W1626592142","https://openalex.org/W1636416079","https://openalex.org/W1680920356","https://openalex.org/W1714107821","https://openalex.org/W1820870565","https://openalex.org/W1923199073","https://openalex.org/W1965046777","https://openalex.org/W1965252376","https://openalex.org/W1965315184","https://openalex.org/W1966530743","https://openalex.org/W1972921528","https://openalex.org/W1973096034","https://openalex.org/W1977088739","https://openalex.org/W1979877576","https://openalex.org/W1980773456","https://openalex.org/W1986812906","https://openalex.org/W1988492494","https://openalex.org/W1994570495","https://openalex.org/W1994665715","https://openalex.org/W1994772282","https://openalex.org/W1995611890","https://openalex.org/W1996912052","https://openalex.org/W1997775470","https://openalex.org/W1997916071","https://openalex.org/W1998217618","https://openalex.org/W1999156442","https://openalex.org/W1999595098","https://openalex.org/W2000653700","https://openalex.org/W2001475156","https://openalex.org/W2004999534","https://openalex.org/W2005723964","https://openalex.org/W2007181246","https://openalex.org/W2008367326","https://openalex.org/W2008640020","https://openalex.org/W2010251088","https://openalex.org/W2010458094","https://openalex.org/W2011397220","https://openalex.org/W2012744885","https://openalex.org/W2017469968","https://openalex.org/W2017532159","https://openalex.org/W2017767253","https://openalex.org/W2024152313","https://openalex.org/W2029231027","https://openalex.org/W2031174583","https://openalex.org/W2036145275","https://openalex.org/W2036428426","https://openalex.org/W2037053580","https://openalex.org/W2037997375","https://openalex.org/W2038577306","https://openalex.org/W2041985227","https://openalex.org/W2044846660","https://openalex.org/W2045371776","https://openalex.org/W2047916715","https://openalex.org/W2048065251","https://openalex.org/W2052750543","https://openalex.org/W2053521858","https://openalex.org/W2053947462","https://openalex.org/W2054092526","https://openalex.org/W2056525230","https://openalex.org/W2061503461","https://openalex.org/W2061533577","https://openalex.org/W2064754325","https://openalex.org/W2065268746","https://openalex.org/W2069083843","https://openalex.org/W2071292533","https://openalex.org/W2072384875","https://openalex.org/W2077192156","https://openalex.org/W2077613352","https://openalex.org/W2081025984","https://openalex.org/W2088028688","https://openalex.org/W2089643815","https://openalex.org/W2092190463","https://openalex.org/W2092296126","https://openalex.org/W2092569072","https://openalex.org/W2098862614","https://openalex.org/W2100704206","https://openalex.org/W2101730120","https://openalex.org/W2113406360","https://openalex.org/W2116364705","https://openalex.org/W2121493672","https://openalex.org/W2121936687","https://openalex.org/W2122534065","https://openalex.org/W2127230663","https://openalex.org/W2128963767","https://openalex.org/W2131545125","https://openalex.org/W2133776873","https://openalex.org/W2140449516","https://openalex.org/W2141367941","https://openalex.org/W2146025254","https://openalex.org/W2148932927","https://openalex.org/W2150642877","https://openalex.org/W2151260274","https://openalex.org/W2152708819","https://openalex.org/W2154346498","https://openalex.org/W2164839855","https://openalex.org/W2166371391","https://openalex.org/W2172027132","https://openalex.org/W2261648044","https://openalex.org/W2322195974","https://openalex.org/W2346006175","https://openalex.org/W2461356528","https://openalex.org/W2476144830","https://openalex.org/W2576742884","https://openalex.org/W4235077732","https://openalex.org/W4253103333"],"related_works":["https://openalex.org/W2105225386","https://openalex.org/W2033533993","https://openalex.org/W4234392447","https://openalex.org/W2020994320","https://openalex.org/W2067845342","https://openalex.org/W2329120949","https://openalex.org/W1222044264","https://openalex.org/W2327355792","https://openalex.org/W2151260274","https://openalex.org/W2050007504"],"abstract_inverted_index":{"Physically":[0],"distinguishable":[1],"microdomains":[2,23,37,56],"associated":[3,127],"with":[4,102,109,119,140,147],"various":[5],"functional":[6,31],"membrane":[7,84],"proteins":[8],"are":[9,74,95],"one":[10],"of":[11,33,86,93,163,167],"the":[12,30,50,83,148],"major":[13],"current":[14],"topics":[15],"in":[16,21,36,55,78],"cell":[17,58,124],"biology.":[18],"Glycosphingolipids":[19,100],"present":[20],"such":[22,72],"have":[24,46],"been":[25],"used":[26],"as":[27,144],"\"markers;\"":[28],"however,":[29],"role":[32],"glycosyl":[34,53],"epitopes":[35,54],"has":[38],"received":[39],"little":[40],"attention.":[41],"In":[42],"this":[43],"review,":[44],"I":[45],"tried":[47],"to":[48,80,159],"summarize":[49],"evidence":[51],"that":[52,64,70,155],"mediate":[57],"adhesion":[59,88,125,137],"and":[60,89,106,126,133,142,165],"signal":[61,104,128],"transduction":[62],"events":[63],"affect":[65],"cellular":[66],"phenotypes.":[67,168],"Molecular":[68],"assemblies":[69],"perform":[71],"functions":[73],"hereby":[75],"termed":[76],"\"glycosynapse\"":[77],"analogy":[79],"\"immunological":[81],"synapse,\"":[82],"assembly":[85],"immunocyte":[87],"signaling.":[90],"Three":[91],"types":[92],"glycosynapses":[94,156],"so":[96],"far":[97],"distinguishable:":[98],"(i)":[99],"organized":[101],"cytoplasmic":[103],"transducers":[105,129],"proteolipid":[107],"tetraspanin":[108,141],"or":[110],"without":[111],"growth":[112],"factor":[113],"receptors;":[114],"(ii)":[115],"transmembrane":[116,136],"mucin-type":[117],"glycoproteins":[118],"clustered":[120],"O-linked":[121],"glycoepitopes":[122],"for":[123],"at":[130],"lipid":[131],"domain;":[132],"(iii)":[134],"N-glycosylated":[135],"receptors":[138],"complexed":[139],"gangliosides,":[143],"typically":[145],"seen":[146],"integrin-tetraspanin-ganglioside":[149],"complex.":[150],"The":[151],"possibility":[152],"is":[153],"discussed":[154],"give":[157],"rise":[158],"a":[160],"high":[161],"degree":[162],"diversity":[164],"complexity":[166]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":20},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":18},{"year":2014,"cited_by_count":21},{"year":2013,"cited_by_count":19},{"year":2012,"cited_by_count":20}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}