{"id":"https://openalex.org/W1871875262","doi":"https://doi.org/10.1128/br.41.3.543-567.1977","title":"Antiviral activity of interferons","display_name":"Antiviral activity of interferons","publication_year":1977,"publication_date":"1977-01-01","ids":{"openalex":"https://openalex.org/W1871875262","doi":"https://doi.org/10.1128/br.41.3.543-567.1977","mag":"1871875262","pmid":"https://pubmed.ncbi.nlm.nih.gov/199154","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/414016"},"language":"en","primary_location":{"id":"doi:10.1128/br.41.3.543-567.1977","doi":"https://doi.org/10.1128/br.41.3.543-567.1977","is_oa":false,"landing_page_url":"https://doi.org/10.1128/br.41.3.543-567.1977","pdf_url":null,"source":{"id":"https://openalex.org/S4210178662","display_name":"Bacteriological Reviews","issn_l":"0005-3678","issn":["0005-3678","2691-9443"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bacteriological Reviews","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC414016","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109118570","display_name":"Robert M. Friedman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"R M Friedman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5109118570"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":12.7034,"has_fulltext":false,"cited_by_count":226,"citation_normalized_percentile":{"value":0.99580468,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"41","issue":"3","first_page":"543","last_page":"567"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interferon","display_name":"interferon","score":0.9950000047683716},{"id":"https://openalex.org/keywords/antiviral-activity","display_name":"antiviral activity","score":0.9980000257492065},{"id":"https://openalex.org/keywords/viral-infection","display_name":"viral infection","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.5210185050964355},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5123387575149536},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.39095306396484375},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3186464309692383}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002474","descriptor_name":"Cell-Free System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004267","descriptor_name":"DNA Viruses","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004267","descriptor_name":"DNA Viruses","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005732","descriptor_name":"Gangliosides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007372","descriptor_name":"Interferons","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007372","descriptor_name":"Interferons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007372","descriptor_name":"Interferons","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D009052","descriptor_name":"Leukemia Virus, Murine","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012328","descriptor_name":"RNA Viruses","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012328","descriptor_name":"RNA Viruses","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012367","descriptor_name":"RNA, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013539","descriptor_name":"Simian virus 40","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013539","descriptor_name":"Simian virus 40","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1128/br.41.3.543-567.1977","doi":"https://doi.org/10.1128/br.41.3.543-567.1977","is_oa":false,"landing_page_url":"https://doi.org/10.1128/br.41.3.543-567.1977","pdf_url":null,"source":{"id":"https://openalex.org/S4210178662","display_name":"Bacteriological Reviews","issn_l":"0005-3678","issn":["0005-3678","2691-9443"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bacteriological Reviews","raw_type":"journal-article"},{"id":"doi:10.1128/mmbr.41.3.543-567.1977","doi":"https://doi.org/10.1128/mmbr.41.3.543-567.1977","is_oa":false,"landing_page_url":"https://doi.org/10.1128/mmbr.41.3.543-567.1977","pdf_url":null,"source":{"id":"https://openalex.org/S4210178662","display_name":"Bacteriological Reviews","issn_l":"0005-3678","issn":["0005-3678","2691-9443"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bacteriological Reviews","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:213814","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC414016","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:414016","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/414016","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bacteriol Rev","raw_type":"Text"},{"id":"pmid:199154","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/199154","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bacteriological reviews","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:213814","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC414016","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"score":0.766700029373169,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":151,"referenced_works":["https://openalex.org/W64190252","https://openalex.org/W176713720","https://openalex.org/W1482953112","https://openalex.org/W1503434985","https://openalex.org/W1507509336","https://openalex.org/W1508144137","https://openalex.org/W1512460569","https://openalex.org/W1514831135","https://openalex.org/W1518450694","https://openalex.org/W1519798017","https://openalex.org/W1533837550","https://openalex.org/W1552941365","https://openalex.org/W1553730538","https://openalex.org/W1564804563","https://openalex.org/W1586827238","https://openalex.org/W1589608483","https://openalex.org/W1594438978","https://openalex.org/W1599985774","https://openalex.org/W1605326822","https://openalex.org/W1662395509","https://openalex.org/W1701773888","https://openalex.org/W1722861930","https://openalex.org/W1755852965","https://openalex.org/W1758307309","https://openalex.org/W1789043736","https://openalex.org/W1892457264","https://openalex.org/W1913974569","https://openalex.org/W1920797582","https://openalex.org/W1937205275","https://openalex.org/W1956740351","https://openalex.org/W1965480496","https://openalex.org/W1966590285","https://openalex.org/W1967172564","https://openalex.org/W1969692384","https://openalex.org/W1973619328","https://openalex.org/W1981805788","https://openalex.org/W1982795083","https://openalex.org/W1983243504","https://openalex.org/W1984991332","https://openalex.org/W1985893537","https://openalex.org/W1988186667","https://openalex.org/W1988343864","https://openalex.org/W1989645056","https://openalex.org/W1991128945","https://openalex.org/W1991344798","https://openalex.org/W1992479112","https://openalex.org/W1994630501","https://openalex.org/W1994905155","https://openalex.org/W1995014058","https://openalex.org/W1996743466","https://openalex.org/W1997383588","https://openalex.org/W1997427139","https://openalex.org/W1998290353","https://openalex.org/W1999350161","https://openalex.org/W2000471952","https://openalex.org/W2001040823","https://openalex.org/W2004953150","https://openalex.org/W2004985169","https://openalex.org/W2007124329","https://openalex.org/W2007474046","https://openalex.org/W2008324411","https://openalex.org/W2008400469","https://openalex.org/W2008629616","https://openalex.org/W2009619990","https://openalex.org/W2010221019","https://openalex.org/W2010516990","https://openalex.org/W2011358976","https://openalex.org/W2012056984","https://openalex.org/W2012459745","https://openalex.org/W2013141442","https://openalex.org/W2014093451","https://openalex.org/W2015536221","https://openalex.org/W2015718622","https://openalex.org/W2015879577","https://openalex.org/W2016663703","https://openalex.org/W2019187844","https://openalex.org/W2019768043","https://openalex.org/W2021717812","https://openalex.org/W2023183967","https://openalex.org/W2024838935","https://openalex.org/W2025496329","https://openalex.org/W2026729363","https://openalex.org/W2028911170","https://openalex.org/W2032807009","https://openalex.org/W2033146669","https://openalex.org/W2034532274","https://openalex.org/W2038436174","https://openalex.org/W2040167525","https://openalex.org/W2040174517","https://openalex.org/W2042191344","https://openalex.org/W2047511510","https://openalex.org/W2050337487","https://openalex.org/W2050999959","https://openalex.org/W2052011052","https://openalex.org/W2053079475","https://openalex.org/W2053579980","https://openalex.org/W2053805303","https://openalex.org/W2054044362","https://openalex.org/W2054666300","https://openalex.org/W2057042710","https://openalex.org/W2057140176","https://openalex.org/W2057981421","https://openalex.org/W2060342012","https://openalex.org/W2061313150","https://openalex.org/W2062346223","https://openalex.org/W2063371319","https://openalex.org/W2063595006","https://openalex.org/W2063729075","https://openalex.org/W2064999289","https://openalex.org/W2066342343","https://openalex.org/W2067429712","https://openalex.org/W2069152963","https://openalex.org/W2071874260","https://openalex.org/W2072042076","https://openalex.org/W2077528494","https://openalex.org/W2077602553","https://openalex.org/W2078262206","https://openalex.org/W2078587814","https://openalex.org/W2081528692","https://openalex.org/W2082688310","https://openalex.org/W2083542338","https://openalex.org/W2083674012","https://openalex.org/W2086633956","https://openalex.org/W2087067045","https://openalex.org/W2087297100","https://openalex.org/W2088445029","https://openalex.org/W2091615096","https://openalex.org/W2092561993","https://openalex.org/W2092976807","https://openalex.org/W2094106168","https://openalex.org/W2099408094","https://openalex.org/W2099872899","https://openalex.org/W2099874422","https://openalex.org/W2120674905","https://openalex.org/W2126102830","https://openalex.org/W2132662997","https://openalex.org/W2140722870","https://openalex.org/W2149651066","https://openalex.org/W2157490015","https://openalex.org/W2164102919","https://openalex.org/W2165723837","https://openalex.org/W2170715582","https://openalex.org/W2171328380","https://openalex.org/W2313432370","https://openalex.org/W2318427794","https://openalex.org/W2323443958","https://openalex.org/W2328290737","https://openalex.org/W2411943647","https://openalex.org/W2414337552","https://openalex.org/W2462820322","https://openalex.org/W4313347962"],"related_works":["https://openalex.org/W2035449519","https://openalex.org/W2051751863","https://openalex.org/W7098514669","https://openalex.org/W2434182208","https://openalex.org/W2403480548","https://openalex.org/W2474767047","https://openalex.org/W2398572759","https://openalex.org/W2396239286","https://openalex.org/W2472999913","https://openalex.org/W2405696625"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}