{"id":"https://openalex.org/W1865247343","doi":null,"title":"The underrecognition and undertreatment of depression: what is the breadth and depth of the problem?","display_name":"The underrecognition and undertreatment of depression: what is the breadth and depth of the problem?","publication_year":1999,"publication_date":"1999-01-01","ids":{"openalex":"https://openalex.org/W1865247343","mag":"1865247343","pmid":"https://pubmed.ncbi.nlm.nih.gov/10326869"},"language":"en","primary_location":{"id":"pmid:10326869","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10326869","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical psychiatry","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101864584","display_name":"Jonathan R. T. Davidson","orcid":"https://orcid.org/0000-0002-8387-8913","observed_orcids":["https://orcid.org/0000-0002-8387-8913"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J R Davidson","raw_affiliation_strings":["Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000446863","display_name":"Samantha E Meltzer-Brody","orcid":"https://orcid.org/0000-0002-8509-408X","observed_orcids":["https://orcid.org/0000-0002-8509-408X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S E Meltzer-Brody","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":8.4043,"has_fulltext":false,"cited_by_count":279,"citation_normalized_percentile":{"value":0.98160163,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"60 Suppl 7","issue":null,"first_page":"4","last_page":"9; discussion 10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10272","display_name":"Mental Health Treatment and Access","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10272","display_name":"Mental Health Treatment and Access","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.018400000408291817,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":0.9459999799728394},{"id":"https://openalex.org/keywords/undertreatment-of-depression","display_name":"undertreatment of depression","score":0.8989999890327454},{"id":"https://openalex.org/keywords/underdiagnosis","display_name":"underdiagnosis","score":0.9679999947547913},{"id":"https://openalex.org/keywords/primary-care","display_name":"primary care","score":0.5370000004768372},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.6290000081062317},{"id":"https://openalex.org/keywords/disability","display_name":"disability","score":0.3700000047683716},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.6650000214576721},{"id":"https://openalex.org/keywords/non-pharmacological-treatment","display_name":"non-pharmacological treatment","score":0.9200000166893005},{"id":"https://openalex.org/keywords/barriers-to-treatment","display_name":"barriers to treatment","score":0.6010000109672546}],"concepts":[{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.8622381687164307},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5364220142364502},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5114387273788452},{"id":"https://openalex.org/C2777286182","wikidata":"https://www.wikidata.org/wiki/Q6746702","display_name":"Management of depression","level":3,"score":0.5104619264602661},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5084094405174255},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.48853573203086853},{"id":"https://openalex.org/C3020448403","wikidata":"https://www.wikidata.org/wiki/Q5282120","display_name":"Burden of disease","level":3,"score":0.4713442027568817},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.45690691471099854},{"id":"https://openalex.org/C2984752397","wikidata":"https://www.wikidata.org/wiki/Q3259956","display_name":"Primary care","level":2,"score":0.3266140818595886},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.15520983934402466},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.093828946352005},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000928","descriptor_name":"Antidepressive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003362","descriptor_name":"Cost-Benefit Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006306","descriptor_name":"Health Surveys","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010555","descriptor_name":"Personality Inventory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011320","descriptor_name":"Primary Health Care","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011613","descriptor_name":"Psychotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017048","descriptor_name":"Health Care Costs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:10326869","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10326869","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical psychiatry","raw_type":"Journal Article"},{"id":"mag:1865247343","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10326869","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W102458143","https://openalex.org/W1520406398","https://openalex.org/W1544781572","https://openalex.org/W1695539136","https://openalex.org/W1748046754","https://openalex.org/W1794946177","https://openalex.org/W1974395071","https://openalex.org/W1996695042","https://openalex.org/W1998714853","https://openalex.org/W2002741313","https://openalex.org/W2003548226","https://openalex.org/W2005564973","https://openalex.org/W2020727834","https://openalex.org/W2058034029","https://openalex.org/W2072833030","https://openalex.org/W2081401651","https://openalex.org/W2094856940","https://openalex.org/W2114613490","https://openalex.org/W2131806832","https://openalex.org/W2159061031","https://openalex.org/W2170332928","https://openalex.org/W2222014932","https://openalex.org/W2424082386","https://openalex.org/W2472195961","https://openalex.org/W2765030473","https://openalex.org/W4240757079","https://openalex.org/W4253268125"],"related_works":["https://openalex.org/W2498309807","https://openalex.org/W192863132","https://openalex.org/W1923157523","https://openalex.org/W790125562","https://openalex.org/W2068169176","https://openalex.org/W2412155497","https://openalex.org/W2076587084","https://openalex.org/W2413918471","https://openalex.org/W1794946177","https://openalex.org/W42450203"],"abstract_inverted_index":{"Currently,":[0],"1":[1],"in":[2,147,166],"6":[3],"of":[4,36,57,72,94,118,130,141,144,157,170],"the":[5,19,31,67,108,142,154,158,168,171],"population":[6],"will,":[7],"at":[8,124,152],"some":[9],"point":[10],"during":[11],"their":[12,105,114],"lives,":[13],"suffer":[14],"from":[15],"major":[16,27,95,162],"depression.":[17],"By":[18],"year":[20],"2020,":[21],"it":[22],"has":[23],"been":[24],"estimated":[25],"that":[26,75,112],"depression":[28,40,73,96,145],"will":[29],"be":[30,78,98],"second":[32],"most":[33,63],"important":[34,64],"cause":[35],"disability":[37],"worldwide.":[38],"Major":[39],"is":[41,74,137],"associated":[42,99],"not":[43],"only":[44],"with":[45,49,100,121],"significant":[46],"morbidity,":[47],"but":[48],"comorbid":[50],"chronic":[51],"illnesses":[52],"and":[53,60,69,92,107,132],"lost":[54],"productivity":[55],"because":[56],"excess":[58],"mortality":[59],"morbidity.":[61],"The":[62,116],"reason":[65],"for":[66,127],"recognition":[68],"adequate":[70],"treatment":[71,117],"symptoms":[76],"can":[77,97],"effectively":[79],"controlled.":[80],"Despite":[81],"this,":[82],"patients":[83,120],"are":[84],"frequently":[85],"neither":[86],"recognized":[87],"nor":[88],"treated":[89],"adequately.":[90],"Underdiagnosis":[91],"undertreatment":[93],"factors":[101],"relating":[102],"to":[103,164],"patients,":[104],"physicians,":[106],"health":[109],"care":[110],"systems":[111],"provide":[113],"care.":[115],"depressed":[119],"appropriate":[122,125,128,134],"agents,":[123],"doses,":[126],"periods":[129],"time,":[131],"incorporating":[133],"nonpharmacologic":[135],"strategies,":[136],"cost-effective.":[138],"Since":[139],"much":[140],"management":[143,156],"occurs":[146],"primary":[148],"care,":[149],"approaches":[150],"aimed":[151],"improving":[153],"overall":[155],"condition":[159],"have":[160],"a":[161],"role":[163],"play":[165],"lessening":[167],"burden":[169],"disease.":[172]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}