{"id":"https://openalex.org/W1861006803","doi":null,"title":"COMPARATIVE ASSESSMENT OF LIPID PROFILE IN PRE-MENOPAUSAL AND MENOPAUSAL WOMEN IN NNEWI NIGERIA","display_name":"COMPARATIVE ASSESSMENT OF LIPID PROFILE IN PRE-MENOPAUSAL AND MENOPAUSAL WOMEN IN NNEWI NIGERIA","publication_year":2015,"publication_date":"2015-10-29","ids":{"openalex":"https://openalex.org/W1861006803","mag":"1861006803"},"language":"en","primary_location":{"id":"mag:1861006803","doi":null,"is_oa":false,"landing_page_url":"http://eujournal.org/index.php/esj/article/viewFile/6354/6105","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034747484","display_name":"PO Manafa","orcid":"https://orcid.org/0000-0003-2356-0345","observed_orcids":["https://orcid.org/0000-0003-2356-0345"]},"institutions":[{"id":"https://openalex.org/I207227095","display_name":"Nnamdi Azikiwe University","ror":"https://ror.org/02r6pfc06","country_code":"NG","type":"education","lineage":["https://openalex.org/I207227095"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"PO Manafa","raw_affiliation_strings":["Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State"],"raw_orcid":"https://orcid.org/0000-0003-2356-0345","affiliations":[{"raw_affiliation_string":"Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State","institution_ids":["https://openalex.org/I207227095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025777169","display_name":"N C Aguiyi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I207227095","display_name":"Nnamdi Azikiwe University","ror":"https://ror.org/02r6pfc06","country_code":"NG","type":"education","lineage":["https://openalex.org/I207227095"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"N C Aguiyi","raw_affiliation_strings":["Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State","institution_ids":["https://openalex.org/I207227095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021226261","display_name":"Charles Chinedum Onyenekwe","orcid":"https://orcid.org/0000-0001-6181-9835","observed_orcids":["https://orcid.org/0000-0001-6181-9835","https://orcid.org/0000-0002-7011-4797"]},"institutions":[{"id":"https://openalex.org/I207227095","display_name":"Nnamdi Azikiwe University","ror":"https://ror.org/02r6pfc06","country_code":"NG","type":"education","lineage":["https://openalex.org/I207227095"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Onyenekwe C.C","raw_affiliation_strings":["Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State","institution_ids":["https://openalex.org/I207227095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087448745","display_name":"George Okechukwu Chukwuma","orcid":"https://orcid.org/0000-0002-7397-2391","observed_orcids":["https://orcid.org/0000-0002-7397-2391"]},"institutions":[{"id":"https://openalex.org/I207227095","display_name":"Nnamdi Azikiwe University","ror":"https://ror.org/02r6pfc06","country_code":"NG","type":"education","lineage":["https://openalex.org/I207227095"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"George O Chukwuma","raw_affiliation_strings":["Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State"],"raw_orcid":"https://orcid.org/0000-0002-7397-2391","affiliations":[{"raw_affiliation_string":"Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State","institution_ids":["https://openalex.org/I207227095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028382440","display_name":"Chizoba Okechukwu Okeke","orcid":"https://orcid.org/0000-0003-0269-095X","observed_orcids":["https://orcid.org/0000-0003-0269-095X"]},"institutions":[{"id":"https://openalex.org/I207227095","display_name":"Nnamdi Azikiwe University","ror":"https://ror.org/02r6pfc06","country_code":"NG","type":"education","lineage":["https://openalex.org/I207227095"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Chizoba Okeke","raw_affiliation_strings":["Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State","institution_ids":["https://openalex.org/I207227095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101635210","display_name":"Augustine Chinedu Ihim","orcid":"https://orcid.org/0000-0001-9991-0714","observed_orcids":["https://orcid.org/0000-0001-9991-0714"]},"institutions":[{"id":"https://openalex.org/I207227095","display_name":"Nnamdi Azikiwe University","ror":"https://ror.org/02r6pfc06","country_code":"NG","type":"education","lineage":["https://openalex.org/I207227095"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Augustine Chinedu Ihim","raw_affiliation_strings":["Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State"],"raw_orcid":"https://orcid.org/0000-0001-9991-0714","affiliations":[{"raw_affiliation_string":"Department of Medical of Medical Laboratory Science,#R##N#Faculty of Health Sciences and Technology,#R##N#Nnamdi Azikiwe University, Nnewi Campus, Anambra State","institution_ids":["https://openalex.org/I207227095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063616831","display_name":"Livinus O Okor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I207227095","display_name":"Nnamdi Azikiwe University","ror":"https://ror.org/02r6pfc06","country_code":"NG","type":"education","lineage":["https://openalex.org/I207227095"]},{"id":"https://openalex.org/I4210142707","display_name":"Nnamdi Azikiwe University Teaching Hospital","ror":"https://ror.org/041q3q398","country_code":"NG","type":"healthcare","lineage":["https://openalex.org/I4210142707"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Livinus O Okor","raw_affiliation_strings":["Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University#R##N#Teaching Hospital, Nnewi Anambra State"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University#R##N#Teaching Hospital, Nnewi Anambra State","institution_ids":["https://openalex.org/I207227095","https://openalex.org/I4210142707"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059823213","display_name":"Chibuzo C Manafa","orcid":"https://orcid.org/0000-0003-1065-4908","observed_orcids":["https://orcid.org/0000-0003-1065-4908"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chibuzor Charles Manafa","raw_affiliation_strings":["Ministry of Health, Rivers state, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ministry of Health, Rivers state, Nigeria","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"11","issue":"30","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/menopause","display_name":"menopause","score":0.9649999737739563},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.9589999914169312},{"id":"https://openalex.org/keywords/premenopausal-women","display_name":"premenopausal women","score":0.9229999780654907},{"id":"https://openalex.org/keywords/menopausal-women","display_name":"menopausal women","score":0.8870000243186951},{"id":"https://openalex.org/keywords/serum-cholesterol","display_name":"serum cholesterol","score":0.7070000171661377},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.8429999947547913},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.9559999704360962},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9950000047683716},{"id":"https://openalex.org/keywords/vldl-cholesterol","display_name":"VLDL cholesterol","score":0.9980000257492065},{"id":"https://openalex.org/keywords/atherogenic-lipids","display_name":"atherogenic lipids","score":0.7170000076293945},{"id":"https://openalex.org/keywords/menopause-duration","display_name":"menopause duration","score":0.9629999995231628}],"concepts":[{"id":"https://openalex.org/C2778562196","wikidata":"https://www.wikidata.org/wiki/Q177708","display_name":"Menopause","level":2,"score":0.7983897924423218},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.6235411763191223},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.6075624227523804},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.573168933391571},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5363854765892029},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5110307931900024},{"id":"https://openalex.org/C8243546","wikidata":"https://www.wikidata.org/wiki/Q419074","display_name":"Very low-density lipoprotein","level":4,"score":0.4752625823020935},{"id":"https://openalex.org/C3019550498","wikidata":"https://www.wikidata.org/wiki/Q28749","display_name":"Ldl cholesterol","level":3,"score":0.41843000054359436},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.41616880893707275},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.3457310199737549},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.32662516832351685}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:1861006803","doi":null,"is_oa":false,"landing_page_url":"http://eujournal.org/index.php/esj/article/viewFile/6354/6105","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W30713965","https://openalex.org/W194056597","https://openalex.org/W1486328468","https://openalex.org/W1565291421","https://openalex.org/W1947690049","https://openalex.org/W1964005327","https://openalex.org/W1964171460","https://openalex.org/W1973217236","https://openalex.org/W1974456981","https://openalex.org/W1977501396","https://openalex.org/W1985986220","https://openalex.org/W2005462461","https://openalex.org/W2024925719","https://openalex.org/W2031322508","https://openalex.org/W2031878247","https://openalex.org/W2054391347","https://openalex.org/W2056818983","https://openalex.org/W2089158718","https://openalex.org/W2090451475","https://openalex.org/W2094325605","https://openalex.org/W2116404316","https://openalex.org/W2137843473","https://openalex.org/W2160654636","https://openalex.org/W2160843928","https://openalex.org/W2186867402","https://openalex.org/W2218787476","https://openalex.org/W2264120673","https://openalex.org/W2782428779"],"related_works":["https://openalex.org/W1985986220","https://openalex.org/W4378567150","https://openalex.org/W2602373639","https://openalex.org/W4386620902","https://openalex.org/W7119493835","https://openalex.org/W3018856447","https://openalex.org/W2974740419","https://openalex.org/W2337359136","https://openalex.org/W2036591209","https://openalex.org/W4389400059"],"abstract_inverted_index":{"The":[0,149,235],"study":[1],"was":[2,44,65,91,126,183],"aimed":[3],"at":[4],"determining":[5],"the":[6,35,47,78,94,111,129,141,153,177,188,203,218,223,227,230],"effect":[7],"of":[8,15,49,62,74,96,113,120,156,191,200,205,210,222,229],"menopause":[9,201],"on":[10],"lipid":[11,231,244],"profile.":[12],"A":[13],"total":[14,75,192],"100":[16],"apparently":[17],"healthy":[18],"subjects":[19,179,225],"who":[20],"comprised":[21],"50":[22,31],"menopausal":[23,173,224,248],"women":[24,33,174,240],"aged":[25,36],"45":[26],"\u2013":[27],"77":[28],"years":[29,39],"and":[30,52,59,99,117,138,160,196,226],"pre-menopausal":[32],"between":[34,37],"20-52":[38],"were":[40,213],"recruited.":[41],"Ethical":[42],"approval":[43],"obtained":[45,66],"from":[46],"Faculty":[48],"Health":[50],"Science":[51],"Technology,":[53],"Nnamdi":[54],"Azikiwe":[55],"University":[56],"ethics":[57],"committee":[58],"informed":[60],"consent":[61],"each":[63],"participant":[64],"prior":[67],"to":[68],"recruitment.":[69],"We":[70],"estimated":[71,127],"serum":[72,157],"levels":[73,155,190,204,228],"cholesterol":[76,164],"using":[77,93,128],"enzymatic":[79,100,118,142],"end":[80],"point":[81],"method":[82,101,119,130,143],"as":[83,102,131,144],"described":[84,103,132,145],"by":[85,104,110,133,140,146],"Roeschlau":[86],"et":[87,106,122,135],"al.,":[88,107,123,136],"(1974),":[89],"HDL":[90],"performed":[92],"combination":[95,112],"phosphotungstate":[97],"precipitation":[98,116],"Burstein":[105],"(1980),":[108],"LDL":[109],"polyvinyl":[114],"sulphate":[115],"Assman":[121],"(1984),":[124],"VLDL":[125],"Friedwald":[134],"(1972)":[137],"triglycerides":[139,158],"Tietz":[147],"(1990).":[148],"results":[150],"shows":[151],"that":[152,238],"mean":[154,189],"(TG)":[159],"low":[161],"density":[162],"lipoprotein":[163],"(LDL":[165],"cholesterol)":[166],"showed":[167],"a":[168,184],"statistically":[169],"significant":[170,215],"increase":[171,186],"in":[172,187],"compared":[175],"with":[176,198,208],"premenopausal":[178,239],"(P":[180],"0.05).":[181],"There":[182,212],"progressive":[185],"cholesterol,":[193],"triglycerides,":[194],"LDL-cholesterol":[195],"VLDLcholesterol":[197],"duration":[199,209],"while":[202],"HDL-cholesterol":[206],"decreased":[207],"menopause.":[211],"no":[214],"variations":[216],"among":[217],"various":[219],"age":[220],"categories":[221],"parameters":[232],"studied":[233],"(p>0.05).":[234],"findings":[236],"suggest":[237],"have":[241],"less":[242],"proatherogenic":[243],"profile":[245],"than":[246],"their":[247],"counterparts.":[249]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2016-06-24T00:00:00"}
